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The map label for this gene is tlpA [H]

Identifier: 154245681

GI number: 154245681

Start: 1954428

End: 1955060

Strand: Reverse

Name: tlpA [H]

Synonym: Xaut_1737

Alternate gene names: 154245681

Gene position: 1955060-1954428 (Counterclockwise)

Preceding gene: 154245685

Following gene: 154245680

Centisome position: 36.83

GC content: 70.14

Gene sequence:

>633_bases
ATGAACCGCCTCCCCGGCAATGCACAGGCGCCTCAGGTCACCTCCGCGCCGGCCGCGGAGCCGGCTGCGTTCAAGGTGTC
GGATGCCGCCTGCCAGGGCACCGTGGAGCGCGCGCGGGCGTTCGTGCCGCTGGCCAAGGGCGGCCTTGCCGCCTTCTCCC
CGGCCACCGAGCCGCGCCGCCTGCCGCCCCTCGCCTTTACCGGCGCCAATGGCAAGGAGGTGACGCTGGCCGACTTCAAA
GGCCGGGTGGTTTTGCTCAATCTCTGGGCGACCTGGTGCGTCCCCTGCCGAAAGGAGATGCCGGACCTCGACCGGCTTCA
GGGCAGCCTGGGCGGGCCGGATTTCGAGGTGGTGGCGGTCAATCTCGACACCCGCGATCCCGACAAGCCTCGGGCCTTCC
TCGACGAGATCGGGGTGAAGCGCCTTGCCTTCTATGCCGACCCGGCAACGAAGACTTTCCAGGCCCTGCGCGGGGTTGGA
CGGGGGTTCGGCCTGCCCACCACGGTCATCGTGGACCGTGACGGCTGCGAGATGGGTTACCTTGCGGGACCTGCCGAATG
GGGCGGTGCCGAGGCTGAGGCTCTGGTCCGCGCGGCGATCGGGACCGGCGCGAGCACATCGCCGGTGCGGTAA

Upstream 100 bases:

>100_bases
GCCTCCCAAGGGGCGGCGCGGCTCCGGCGTGCGGACCGTCGGTCTCGTCGCGCTGGCGACGCTGGCGGGCGCCGTTGCCG
GCGCGCTCGCCCTATACGGG

Downstream 100 bases:

>100_bases
CACCATGTAGGCGTGAATTTCGCATTTTGCGAAATAAGGATTTTGGGCTTAAGTGTCGCTCAACCTTCTCTGTTCACAGT
GCGTGACCATGGAAGGGGAG

Product: redoxin domain-containing protein

Products: NA

Alternate protein names: Cytochrome c biogenesis protein tlpA [H]

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MNRLPGNAQAPQVTSAPAAEPAAFKVSDAACQGTVERARAFVPLAKGGLAAFSPATEPRRLPPLAFTGANGKEVTLADFK
GRVVLLNLWATWCVPCRKEMPDLDRLQGSLGGPDFEVVAVNLDTRDPDKPRAFLDEIGVKRLAFYADPATKTFQALRGVG
RGFGLPTTVIVDRDGCEMGYLAGPAEWGGAEAEALVRAAIGTGASTSPVR

Sequences:

>Translated_210_residues
MNRLPGNAQAPQVTSAPAAEPAAFKVSDAACQGTVERARAFVPLAKGGLAAFSPATEPRRLPPLAFTGANGKEVTLADFK
GRVVLLNLWATWCVPCRKEMPDLDRLQGSLGGPDFEVVAVNLDTRDPDKPRAFLDEIGVKRLAFYADPATKTFQALRGVG
RGFGLPTTVIVDRDGCEMGYLAGPAEWGGAEAEALVRAAIGTGASTSPVR
>Mature_210_residues
MNRLPGNAQAPQVTSAPAAEPAAFKVSDAACQGTVERARAFVPLAKGGLAAFSPATEPRRLPPLAFTGANGKEVTLADFK
GRVVLLNLWATWCVPCRKEMPDLDRLQGSLGGPDFEVVAVNLDTRDPDKPRAFLDEIGVKRLAFYADPATKTFQALRGVG
RGFGLPTTVIVDRDGCEMGYLAGPAEWGGAEAEALVRAAIGTGASTSPVR

Specific function: Involved in cytochrome aa3 assembly [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013740
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 22078; Mature: 22078

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRLPGNAQAPQVTSAPAAEPAAFKVSDAACQGTVERARAFVPLAKGGLAAFSPATEPRR
CCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCC
LPPLAFTGANGKEVTLADFKGRVVLLNLWATWCVPCRKEMPDLDRLQGSLGGPDFEVVAV
CCCEEEECCCCCEEEEEECCCCEEEEEEHHHHHHHHHHCCCCHHHHHHCCCCCCEEEEEE
NLDTRDPDKPRAFLDEIGVKRLAFYADPATKTFQALRGVGRGFGLPTTVIVDRDGCEMGY
EECCCCCCCHHHHHHHHCHHHEEEECCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCE
LAGPAEWGGAEAEALVRAAIGTGASTSPVR
ECCCCCCCCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNRLPGNAQAPQVTSAPAAEPAAFKVSDAACQGTVERARAFVPLAKGGLAAFSPATEPRR
CCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCC
LPPLAFTGANGKEVTLADFKGRVVLLNLWATWCVPCRKEMPDLDRLQGSLGGPDFEVVAV
CCCEEEECCCCCEEEEEECCCCEEEEEEHHHHHHHHHHCCCCHHHHHHCCCCCCEEEEEE
NLDTRDPDKPRAFLDEIGVKRLAFYADPATKTFQALRGVGRGFGLPTTVIVDRDGCEMGY
EECCCCCCCHHHHHHHHCHHHEEEECCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCE
LAGPAEWGGAEAEALVRAAIGTGASTSPVR
ECCCCCCCCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8253065; 12597275 [H]