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The map label for this gene is yciR [C]

Identifier: 154245685

GI number: 154245685

Start: 1958527

End: 1959858

Strand: Reverse

Name: yciR [C]

Synonym: Xaut_1741

Alternate gene names: 154245685

Gene position: 1959858-1958527 (Counterclockwise)

Preceding gene: 154245686

Following gene: 154245681

Centisome position: 36.92

GC content: 65.92

Gene sequence:

>1332_bases
GTGAGCGACGCCGACGATGGAGCGCGTGGACCCTGGAAATCGGAATATCTTGCCCTGCACGACCCGGTGACCAGCCTGCC
CAATCGCCTCTTGATGACCGAGTTCCTCGCCGGCGCGCTCAGCTCGCCGCAGGAAACCCGGCGGATGTTGGCCGTTTTCT
GCATCGACCTCGATAATTTCCACCATTTCAACGAGATGTTCGGCCTGGACGCGGGTGACCTCATCCTCGCCGAGACCGCG
CGGCGGATCCGCCGGTGCGTGCGCGACCATGACCTGGTGGCGCGGGTGGATGCCGACACCTTCATCATCGTCGCCACCGG
TGTCGGGGATGCGAAGGCGGTGGACGGCCTGACCCGACGGCTTCAGTCGGCCCTGAACGCGCCCATCGGCATGTCGTCCG
GCGCGGTGGCCTACCCGCTGGTCAACATGGGCATCGCCCTCGCCCCGCTCGATGCGGAGGATGCCGAGGGTCTCGTGCGC
TGCGCCGAGTTGGCGCTGGAGCAGGCCAAGGCCGACGGTCCCGGCACCTGTTCCTACTTCGCCGACGATGTGAACGAGGA
GATGAGCGGACGGCGGACGCTGGAAGGCGACCTCAGGCGGGCCATCGTATCCGACGAGTTCGTGCTGCTGTTCCAGCCGC
GCTGCGACGCGCGGACGCTGAAGCTGCTCGGGGTGGAGGCCCTGATCCGCTGGGACCATCCCCAGCTGGGGTTGCTGACC
CCCGACGCGTTCGTCCCCATCGCCGAGAAGAGCGGCCTCGTCATTCCCATCGGCGAATGGGTGCTGCGCAAGGCGTGCGA
CACCATCTCCCGCCTGCCGGAGCTGAACGTCTCCGTCAACGTCTCGGTGGTGCAGTTCCGCAATGATGCGCTCGTCAACA
CGGTGGATGCGGTGCTCAAAAGCACCCGCGTTGCGCCGGAGCGGCTTGAGCTCGAAATCACCGAGAGCGTACTGATCGAG
AATGCCGAGAAGGCGCTTGAGGTGCTGGAGGGCCTGAAAAACCTGGGCGTGCGCCTGTCCATGGACGATTTCGGCACCGG
CTATTCATCGCTGGGCTATCTGCGGACCTTCCCGTTCGACGCCCTGAAGATCGATCGGCGCTTTGTCGGCGACCTGGACA
ATTCCAAGGGCGCGCTTGCCATCGTGCAGGCGATCCTGGGCCTTGGGCGCGCGCTCGGCATGCAGGTGGTGGCGGAAGGG
GTGGAGACGGAGAGCCAGCTCGCCATTCTCAGGGCCGATTCCTGCGACGAGGTCCAGGGCTTCTTCCTGGGCCATCCCAT
GACCGAAGAGGCGTTGCTCGCCTTTATCGCCGACCGCCGGCTGGCGAGCTGA

Upstream 100 bases:

>100_bases
GGCCGGGGGACGAGGGGATGTGCCAATCGTCGAAGGGGCCGACCTTCTGGGGCGTCCCGGTCGCCGGCGGGCCATCGCAA
CGATCGGCATTGGGTGATTT

Downstream 100 bases:

>100_bases
GCGCCGGCCCGGTCCGGCCTGCGTGCAGCGTCATCGAGGGCAGGCGGACGAGGGCAGGCGGATAACGCCCTCCAGACTCA
GGCCAGCCAGGGCGCGGGGC

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 442

Protein sequence:

>443_residues
MSDADDGARGPWKSEYLALHDPVTSLPNRLLMTEFLAGALSSPQETRRMLAVFCIDLDNFHHFNEMFGLDAGDLILAETA
RRIRRCVRDHDLVARVDADTFIIVATGVGDAKAVDGLTRRLQSALNAPIGMSSGAVAYPLVNMGIALAPLDAEDAEGLVR
CAELALEQAKADGPGTCSYFADDVNEEMSGRRTLEGDLRRAIVSDEFVLLFQPRCDARTLKLLGVEALIRWDHPQLGLLT
PDAFVPIAEKSGLVIPIGEWVLRKACDTISRLPELNVSVNVSVVQFRNDALVNTVDAVLKSTRVAPERLELEITESVLIE
NAEKALEVLEGLKNLGVRLSMDDFGTGYSSLGYLRTFPFDALKIDRRFVGDLDNSKGALAIVQAILGLGRALGMQVVAEG
VETESQLAILRADSCDEVQGFFLGHPMTEEALLAFIADRRLAS

Sequences:

>Translated_443_residues
MSDADDGARGPWKSEYLALHDPVTSLPNRLLMTEFLAGALSSPQETRRMLAVFCIDLDNFHHFNEMFGLDAGDLILAETA
RRIRRCVRDHDLVARVDADTFIIVATGVGDAKAVDGLTRRLQSALNAPIGMSSGAVAYPLVNMGIALAPLDAEDAEGLVR
CAELALEQAKADGPGTCSYFADDVNEEMSGRRTLEGDLRRAIVSDEFVLLFQPRCDARTLKLLGVEALIRWDHPQLGLLT
PDAFVPIAEKSGLVIPIGEWVLRKACDTISRLPELNVSVNVSVVQFRNDALVNTVDAVLKSTRVAPERLELEITESVLIE
NAEKALEVLEGLKNLGVRLSMDDFGTGYSSLGYLRTFPFDALKIDRRFVGDLDNSKGALAIVQAILGLGRALGMQVVAEG
VETESQLAILRADSCDEVQGFFLGHPMTEEALLAFIADRRLAS
>Mature_442_residues
SDADDGARGPWKSEYLALHDPVTSLPNRLLMTEFLAGALSSPQETRRMLAVFCIDLDNFHHFNEMFGLDAGDLILAETAR
RIRRCVRDHDLVARVDADTFIIVATGVGDAKAVDGLTRRLQSALNAPIGMSSGAVAYPLVNMGIALAPLDAEDAEGLVRC
AELALEQAKADGPGTCSYFADDVNEEMSGRRTLEGDLRRAIVSDEFVLLFQPRCDARTLKLLGVEALIRWDHPQLGLLTP
DAFVPIAEKSGLVIPIGEWVLRKACDTISRLPELNVSVNVSVVQFRNDALVNTVDAVLKSTRVAPERLELEITESVLIEN
AEKALEVLEGLKNLGVRLSMDDFGTGYSSLGYLRTFPFDALKIDRRFVGDLDNSKGALAIVQAILGLGRALGMQVVAEGV
ETESQLAILRADSCDEVQGFFLGHPMTEEALLAFIADRRLAS

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=430, Percent_Identity=32.7906976744186, Blast_Score=247, Evalue=1e-66,
Organism=Escherichia coli, GI87081921, Length=431, Percent_Identity=30.1624129930394, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI226510982, Length=420, Percent_Identity=28.0952380952381, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1790496, Length=243, Percent_Identity=31.6872427983539, Blast_Score=148, Evalue=6e-37,
Organism=Escherichia coli, GI87081845, Length=252, Percent_Identity=35.7142857142857, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI87081980, Length=240, Percent_Identity=32.0833333333333, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1788502, Length=245, Percent_Identity=31.8367346938775, Blast_Score=134, Evalue=8e-33,
Organism=Escherichia coli, GI1786507, Length=244, Percent_Identity=31.9672131147541, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1787055, Length=390, Percent_Identity=27.1794871794872, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI87081743, Length=242, Percent_Identity=28.5123966942149, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI87082096, Length=437, Percent_Identity=25.858123569794, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1788849, Length=250, Percent_Identity=28.8, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI87081977, Length=156, Percent_Identity=26.9230769230769, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1787410, Length=227, Percent_Identity=25.9911894273128, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014
- InterPro:   IPR013767 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT; PF00989 PAS [H]

EC number: NA

Molecular weight: Translated: 48207; Mature: 48076

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDADDGARGPWKSEYLALHDPVTSLPNRLLMTEFLAGALSSPQETRRMLAVFCIDLDNF
CCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEECCCH
HHFNEMFGLDAGDLILAETARRIRRCVRDHDLVARVDADTFIIVATGVGDAKAVDGLTRR
HHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCEEEEEEECCCCHHHHHHHHHH
LQSALNAPIGMSSGAVAYPLVNMGIALAPLDAEDAEGLVRCAELALEQAKADGPGTCSYF
HHHHHCCCCCCCCCCHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHH
ADDVNEEMSGRRTLEGDLRRAIVSDEFVLLFQPRCDARTLKLLGVEALIRWDHPQLGLLT
HHHHHHHHCCCCCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHEECCCCCCCEEC
PDAFVPIAEKSGLVIPIGEWVLRKACDTISRLPELNVSVNVSVVQFRNDALVNTVDAVLK
CCCCCEEECCCCEEEEHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCHHHHHHHHHHH
STRVAPERLELEITESVLIENAEKALEVLEGLKNLGVRLSMDDFGTGYSSLGYLRTFPFD
HHCCCHHHHEEEHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHCCCCHHHCCHHHHCCCH
ALKIDRRFVGDLDNSKGALAIVQAILGLGRALGMQVVAEGVETESQLAILRADSCDEVQG
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHH
FFLGHPMTEEALLAFIADRRLAS
HHCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SDADDGARGPWKSEYLALHDPVTSLPNRLLMTEFLAGALSSPQETRRMLAVFCIDLDNF
CCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEECCCH
HHFNEMFGLDAGDLILAETARRIRRCVRDHDLVARVDADTFIIVATGVGDAKAVDGLTRR
HHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCEEEEEEECCCCHHHHHHHHHH
LQSALNAPIGMSSGAVAYPLVNMGIALAPLDAEDAEGLVRCAELALEQAKADGPGTCSYF
HHHHHCCCCCCCCCCHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHH
ADDVNEEMSGRRTLEGDLRRAIVSDEFVLLFQPRCDARTLKLLGVEALIRWDHPQLGLLT
HHHHHHHHCCCCCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHEECCCCCCCEEC
PDAFVPIAEKSGLVIPIGEWVLRKACDTISRLPELNVSVNVSVVQFRNDALVNTVDAVLK
CCCCCEEECCCCEEEEHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCHHHHHHHHHHH
STRVAPERLELEITESVLIENAEKALEVLEGLKNLGVRLSMDDFGTGYSSLGYLRTFPFD
HHCCCHHHHEEEHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHCCCCHHHCCHHHHCCCH
ALKIDRRFVGDLDNSKGALAIVQAILGLGRALGMQVVAEGVETESQLAILRADSCDEVQG
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHH
FFLGHPMTEEALLAFIADRRLAS
HHCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]