Click here to switch to the map view.

The map label for this gene is glsA [H]

Identifier: 154245111

GI number: 154245111

Start: 1338991

End: 1339986

Strand: Direct

Name: glsA [H]

Synonym: Xaut_1163

Alternate gene names: 154245111

Gene position: 1338991-1339986 (Clockwise)

Preceding gene: 154245110

Following gene: 154245113

Centisome position: 25.22

GC content: 66.57

Gene sequence:

>996_bases
ATGCCGGACGTGTCATCGATCCCGGAGAACGAGCGGGTGTATGGGCTCAAGGGTGTGCTGGAGCATAGCTTCGAGCGCAC
CCGCCACGACGCCTCAGGCGCGCTTGCCGACTACATTCCCGAACTCGCCAAGGCCGATCCCGACCGTTTCGGCATCGCAA
TGGCCTCGGTCTCCGGCGAGGTGGTGGGCGTGGGCGACGTGGATCTGCCCTTCACCATCCAGTCCATTTCCAAGGCGCTG
GCCTATTGCCTGGCGCTGGAGGCGCTGGGCCGGGACAAGGTGCTCGCCCATGTGGGCGTCGAGCCGTCCGGCGATGCCTT
CAACGCCATCGTCTTCGATGCGCTGTCCAACCGCCCCTTCAATCCCATGGTGAATGCCGGGGCCATCACCGTGTCCGGCC
TTCTTTCGGAAGCGTTCGGGGCGGAGGCATTCGAGGTGGTGCTGGATCGCTTCTCCGCTGCCGCCGGCCGCCGGCTGGTG
ATGGACGAGACCGTGTTCCGCTCCGAGGCGCAGACCGGCCACCGCAACCGCGGCATCGCCCATCTGCTGAAATGCGCGGG
CGCGCTCGGCGCCGATGTGGACGACGCGGTCGACCTTTATTTCCGCCAGTGCTCCATCCTCGTCACCGCCACGGATCTTG
CGGTGATGGGGGCGACGCTGGCCAATATCGGTGAAAATCCGCTCACCGGCAGCGCCGCGTTCGCGGTGGAGGCGGTGCGC
AACACCCTGTCGGTGATGTTCACCTGCGGCATGTATGATTTTGCCGGCAACTGGGCCTTCGACGTGGGCGTGCCGGCGAA
AAGCGGAGTGGGCGGCGGCATCCTCGGCGTGGTGAACCGCCAATTGGGCATCGGCACCTATTCGCCGCGCCTGGACGCCA
AGGGCAATTCGGTGCGCGGCATCTCGGCCTTCCGCGACCTCGCCGAAGAGATGGGGCTGCACGTGTTCGACCCCACCAAC
CGCGGCTCGTCCCTGCTCAGCGCCTATCGGCGCTGA

Upstream 100 bases:

>100_bases
GAACGCGGTCCCGCCGCGCCGCCGCCGGCCCGTCTCTTGCATGATATTCAGGCACAAGCCGAATCGGACCTGATCCGGCC
GATCGGCGGGGCGGGAAGGA

Downstream 100 bases:

>100_bases
ACCGGCTTTTGCGCTCCAGCGCGGCAGGGAAGGACTGAAGGGGAAACGGCCGGCTCAAGGCCGGCCGGATCAGGCGTGCG
GCTCAGGAGCAGCGCACATA

Product: glutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MPDVSSIPENERVYGLKGVLEHSFERTRHDASGALADYIPELAKADPDRFGIAMASVSGEVVGVGDVDLPFTIQSISKAL
AYCLALEALGRDKVLAHVGVEPSGDAFNAIVFDALSNRPFNPMVNAGAITVSGLLSEAFGAEAFEVVLDRFSAAAGRRLV
MDETVFRSEAQTGHRNRGIAHLLKCAGALGADVDDAVDLYFRQCSILVTATDLAVMGATLANIGENPLTGSAAFAVEAVR
NTLSVMFTCGMYDFAGNWAFDVGVPAKSGVGGGILGVVNRQLGIGTYSPRLDAKGNSVRGISAFRDLAEEMGLHVFDPTN
RGSSLLSAYRR

Sequences:

>Translated_331_residues
MPDVSSIPENERVYGLKGVLEHSFERTRHDASGALADYIPELAKADPDRFGIAMASVSGEVVGVGDVDLPFTIQSISKAL
AYCLALEALGRDKVLAHVGVEPSGDAFNAIVFDALSNRPFNPMVNAGAITVSGLLSEAFGAEAFEVVLDRFSAAAGRRLV
MDETVFRSEAQTGHRNRGIAHLLKCAGALGADVDDAVDLYFRQCSILVTATDLAVMGATLANIGENPLTGSAAFAVEAVR
NTLSVMFTCGMYDFAGNWAFDVGVPAKSGVGGGILGVVNRQLGIGTYSPRLDAKGNSVRGISAFRDLAEEMGLHVFDPTN
RGSSLLSAYRR
>Mature_330_residues
PDVSSIPENERVYGLKGVLEHSFERTRHDASGALADYIPELAKADPDRFGIAMASVSGEVVGVGDVDLPFTIQSISKALA
YCLALEALGRDKVLAHVGVEPSGDAFNAIVFDALSNRPFNPMVNAGAITVSGLLSEAFGAEAFEVVLDRFSAAAGRRLVM
DETVFRSEAQTGHRNRGIAHLLKCAGALGADVDDAVDLYFRQCSILVTATDLAVMGATLANIGENPLTGSAAFAVEAVRN
TLSVMFTCGMYDFAGNWAFDVGVPAKSGVGGGILGVVNRQLGIGTYSPRLDAKGNSVRGISAFRDLAEEMGLHVFDPTNR
GSSLLSAYRR

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaminase family [H]

Homologues:

Organism=Homo sapiens, GI156104878, Length=302, Percent_Identity=43.7086092715232, Blast_Score=245, Evalue=5e-65,
Organism=Homo sapiens, GI20336214, Length=315, Percent_Identity=42.8571428571429, Blast_Score=237, Evalue=1e-62,
Organism=Escherichia coli, GI1786693, Length=302, Percent_Identity=38.0794701986755, Blast_Score=204, Evalue=8e-54,
Organism=Escherichia coli, GI1787804, Length=301, Percent_Identity=35.5481727574751, Blast_Score=176, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17507019, Length=320, Percent_Identity=40, Blast_Score=233, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI17532727, Length=309, Percent_Identity=38.8349514563107, Blast_Score=232, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI193204073, Length=308, Percent_Identity=37.3376623376623, Blast_Score=214, Evalue=5e-56,
Organism=Caenorhabditis elegans, GI193204075, Length=310, Percent_Identity=36.7741935483871, Blast_Score=213, Evalue=1e-55,
Organism=Drosophila melanogaster, GI24653162, Length=307, Percent_Identity=38.4364820846906, Blast_Score=230, Evalue=1e-60,
Organism=Drosophila melanogaster, GI281363239, Length=307, Percent_Identity=38.4364820846906, Blast_Score=230, Evalue=1e-60,
Organism=Drosophila melanogaster, GI24653158, Length=307, Percent_Identity=38.4364820846906, Blast_Score=229, Evalue=1e-60,
Organism=Drosophila melanogaster, GI281363241, Length=307, Percent_Identity=38.4364820846906, Blast_Score=229, Evalue=1e-60,
Organism=Drosophila melanogaster, GI24653166, Length=307, Percent_Identity=38.4364820846906, Blast_Score=229, Evalue=1e-60,
Organism=Drosophila melanogaster, GI24653164, Length=307, Percent_Identity=38.4364820846906, Blast_Score=229, Evalue=1e-60,
Organism=Drosophila melanogaster, GI24653156, Length=307, Percent_Identity=38.4364820846906, Blast_Score=229, Evalue=2e-60,
Organism=Drosophila melanogaster, GI116008307, Length=307, Percent_Identity=38.4364820846906, Blast_Score=229, Evalue=2e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015868 [H]

Pfam domain/function: PF04960 Glutaminase [H]

EC number: =3.5.1.2 [H]

Molecular weight: Translated: 34879; Mature: 34748

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDVSSIPENERVYGLKGVLEHSFERTRHDASGALADYIPELAKADPDRFGIAMASVSGE
CCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHEEEEEECCCC
VVGVGDVDLPFTIQSISKALAYCLALEALGRDKVLAHVGVEPSGDAFNAIVFDALSNRPF
EEEECCCCCCEEHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCC
NPMVNAGAITVSGLLSEAFGAEAFEVVLDRFSAAAGRRLVMDETVFRSEAQTGHRNRGIA
CCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHCCCCCCCHH
HLLKCAGALGADVDDAVDLYFRQCSILVTATDLAVMGATLANIGENPLTGSAAFAVEAVR
HHHHHHHHCCCCHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
NTLSVMFTCGMYDFAGNWAFDVGVPAKSGVGGGILGVVNRQLGIGTYSPRLDAKGNSVRG
HHHHHHHHHCCHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCH
ISAFRDLAEEMGLHVFDPTNRGSSLLSAYRR
HHHHHHHHHHCCCEEECCCCCCHHHHHHHCC
>Mature Secondary Structure 
PDVSSIPENERVYGLKGVLEHSFERTRHDASGALADYIPELAKADPDRFGIAMASVSGE
CCCCCCCCCCCEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHEEEEEECCCC
VVGVGDVDLPFTIQSISKALAYCLALEALGRDKVLAHVGVEPSGDAFNAIVFDALSNRPF
EEEECCCCCCEEHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCC
NPMVNAGAITVSGLLSEAFGAEAFEVVLDRFSAAAGRRLVMDETVFRSEAQTGHRNRGIA
CCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHCCCCCCCHH
HLLKCAGALGADVDDAVDLYFRQCSILVTATDLAVMGATLANIGENPLTGSAAFAVEAVR
HHHHHHHHCCCCHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
NTLSVMFTCGMYDFAGNWAFDVGVPAKSGVGGGILGVVNRQLGIGTYSPRLDAKGNSVRG
HHHHHHHHHCCHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCH
ISAFRDLAEEMGLHVFDPTNRGSSLLSAYRR
HHHHHHHHHHCCCEEECCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA