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The map label for this gene is groS2 [H]

Identifier: 154245113

GI number: 154245113

Start: 1340912

End: 1341202

Strand: Direct

Name: groS2 [H]

Synonym: Xaut_1165

Alternate gene names: 154245113

Gene position: 1340912-1341202 (Clockwise)

Preceding gene: 154245111

Following gene: 154245114

Centisome position: 25.26

GC content: 65.29

Gene sequence:

>291_bases
ATGTCCTTCCGTCCCCTGCACGACCGCGTCGTGGTCAAGCGCATCGAAGCCGAGCAGAAGACCGCCGGCGGCATCATCAT
CCCCGACACCGCCAAGGAAAAGCCCCAGGAGGGCGAGGTGATCGCGGTGGGCGCCGGTGCGCGCGACGAGGCCGGCAAGC
TGGTTCCCCTCGACGTGAAGGCGGGCGACCGGGTGCTGTTCGGCAAGTGGTCCGGCACCGAAGTGAAGATCGACGGCCAG
GACCTTCTCATCATGAAGGAGAGCGACATCCTCGGTGTCATCACCAAGTGA

Upstream 100 bases:

>100_bases
GGGGTGGCCCGCTTATCTCCGCTGCGAGCTTGGCACTCCACCTTGGAGAGTGCCAGAACCGGCGGGCCAGAGGCTCGCGT
CCCTCGGAGAGGTAAAAACA

Downstream 100 bases:

>100_bases
GTGGTGTTGCCGGTTGAGTGTCGCTGCCGCGTGCGGGTTTCGCCAAGTGATGCCAGGTGATGGCGGCCTGAACGCACCCC
ATAATCCCAGAATTTAGGAG

Product: chaperonin Cpn10

Products: NA

Alternate protein names: GroES protein 2; Protein Cpn10 2 [H]

Number of amino acids: Translated: 96; Mature: 95

Protein sequence:

>96_residues
MSFRPLHDRVVVKRIEAEQKTAGGIIIPDTAKEKPQEGEVIAVGAGARDEAGKLVPLDVKAGDRVLFGKWSGTEVKIDGQ
DLLIMKESDILGVITK

Sequences:

>Translated_96_residues
MSFRPLHDRVVVKRIEAEQKTAGGIIIPDTAKEKPQEGEVIAVGAGARDEAGKLVPLDVKAGDRVLFGKWSGTEVKIDGQ
DLLIMKESDILGVITK
>Mature_95_residues
SFRPLHDRVVVKRIEAEQKTAGGIIIPDTAKEKPQEGEVIAVGAGARDEAGKLVPLDVKAGDRVLFGKWSGTEVKIDGQD
LLIMKESDILGVITK

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter [H]

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family [H]

Homologues:

Organism=Homo sapiens, GI4504523, Length=90, Percent_Identity=42.2222222222222, Blast_Score=70, Evalue=4e-13,
Organism=Homo sapiens, GI169210012, Length=90, Percent_Identity=40, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1790585, Length=95, Percent_Identity=52.6315789473684, Blast_Score=95, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17555568, Length=93, Percent_Identity=48.3870967741936, Blast_Score=97, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6324594, Length=96, Percent_Identity=40.625, Blast_Score=72, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21356029, Length=90, Percent_Identity=45.5555555555556, Blast_Score=79, Evalue=7e-16,
Organism=Drosophila melanogaster, GI21358317, Length=89, Percent_Identity=43.8202247191011, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032 [H]

Pfam domain/function: PF00166 Cpn10 [H]

EC number: NA

Molecular weight: Translated: 10351; Mature: 10220

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFRPLHDRVVVKRIEAEQKTAGGIIIPDTAKEKPQEGEVIAVGAGARDEAGKLVPLDVK
CCCCCCCCCEEEEECCCCCCCCCCEEECCCCCCCCCCCCEEEEECCCCCCCCCEEEEECC
AGDRVLFGKWSGTEVKIDGQDLLIMKESDILGVITK
CCCEEEEECCCCCEEEECCCEEEEEECCCEEEEEEC
>Mature Secondary Structure 
SFRPLHDRVVVKRIEAEQKTAGGIIIPDTAKEKPQEGEVIAVGAGARDEAGKLVPLDVK
CCCCCCCCEEEEECCCCCCCCCCEEECCCCCCCCCCCCEEEEECCCCCCCCCEEEEECC
AGDRVLFGKWSGTEVKIDGQDLLIMKESDILGVITK
CCCEEEEECCCCCEEEECCCEEEEEECCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]