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The map label for this gene is mhpR [H]

Identifier: 154244876

GI number: 154244876

Start: 1044414

End: 1045226

Strand: Reverse

Name: mhpR [H]

Synonym: Xaut_0926

Alternate gene names: 154244876

Gene position: 1045226-1044414 (Counterclockwise)

Preceding gene: 154244877

Following gene: 154244860

Centisome position: 19.69

GC content: 67.53

Gene sequence:

>813_bases
ATGGGCCAGCGACTGGCTGACGAGCGCGCGACCACGCCGGACCGCAGCGACAGCGTGCGCGCCTTGCGCCGAGGGCTCGC
GGTGCTGCGCTATATCAACGCGGTGGGCAGCACCAATGCCGCCTCCATCGCCCGCGCCCTCGATATCCCGCGCCCCACCG
TCTACCGCCTGCTGCAAACCCTGGAGGAGGAAGGCTACGTGGCCTTTTCCGCCTCCTCGACGCAGGTCCGGGTCACGCGC
CTCTCCGCCAGTCTTGGCGACGGCTATGCAGCGCATTCCCGGGTGTGCCAGGTCGCGGCCCCGGTGTTCGGCGAATACGG
CCCGCGTCTGGTGTGGCCGCTCGACCTGACGGTGTATGAGAACGCCGCCATGGTGATCCACGAGACCACGCACACGCGCA
GCCCGCTCTCCATCGACCGTGGCATGATCGGCTATCGCTTGCCCATGCTGCGTACCTCGGCCGGCCGGGCCTACCTGGCC
TTCTGCAGGGAGGAGGAGCGGGCAATGATCCTGGATCACCTGCGCCGCATCCACGATCCCGAGGACCGCCCTTTCCTCGA
CGAGGCATGGCTTGGACGCATGATCGAGGAGACCCGGCGGCGCGCCGTTGCCGTGCGCGACGGGGGTGAGTTCAGGCCGA
AGACATCCAGCATTGCCGTTCCCGTCTTGATCGGCGACCGCGTCGAGGCGGTGGTATCGATGATCTGGATCCGCTCCGCG
CTGTCCCTGGATGATGCCCTTTCGGCCCATTCCGAGGCGCTGGCATCTATCGCGACCGCCATTGCGCGTGACGTCTCCGC
TCAGCAGAAATAG

Upstream 100 bases:

>100_bases
CCGGGCAAGTCTGGGCACGGCATGTTCAAAACGTATACCATGTGAACCAAAAGACCGGATCGTCCGGCTGGGTGGGGAAC
GCCGAGGATTGGGTCGGACC

Downstream 100 bases:

>100_bases
GTGCTGCACGATAGCCCTGCCGACCGGTGCAGGCGTGCAAGCGCGGGGCAGATGCACGTCCGCAGCATGCTCAATCTGCG
CCAGCGCGGCGATCTTGAGG

Product: DNA-binding transcriptional activator MhpR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MGQRLADERATTPDRSDSVRALRRGLAVLRYINAVGSTNAASIARALDIPRPTVYRLLQTLEEEGYVAFSASSTQVRVTR
LSASLGDGYAAHSRVCQVAAPVFGEYGPRLVWPLDLTVYENAAMVIHETTHTRSPLSIDRGMIGYRLPMLRTSAGRAYLA
FCREEERAMILDHLRRIHDPEDRPFLDEAWLGRMIEETRRRAVAVRDGGEFRPKTSSIAVPVLIGDRVEAVVSMIWIRSA
LSLDDALSAHSEALASIATAIARDVSAQQK

Sequences:

>Translated_270_residues
MGQRLADERATTPDRSDSVRALRRGLAVLRYINAVGSTNAASIARALDIPRPTVYRLLQTLEEEGYVAFSASSTQVRVTR
LSASLGDGYAAHSRVCQVAAPVFGEYGPRLVWPLDLTVYENAAMVIHETTHTRSPLSIDRGMIGYRLPMLRTSAGRAYLA
FCREEERAMILDHLRRIHDPEDRPFLDEAWLGRMIEETRRRAVAVRDGGEFRPKTSSIAVPVLIGDRVEAVVSMIWIRSA
LSLDDALSAHSEALASIATAIARDVSAQQK
>Mature_269_residues
GQRLADERATTPDRSDSVRALRRGLAVLRYINAVGSTNAASIARALDIPRPTVYRLLQTLEEEGYVAFSASSTQVRVTRL
SASLGDGYAAHSRVCQVAAPVFGEYGPRLVWPLDLTVYENAAMVIHETTHTRSPLSIDRGMIGYRLPMLRTSAGRAYLAF
CREEERAMILDHLRRIHDPEDRPFLDEAWLGRMIEETRRRAVAVRDGGEFRPKTSSIAVPVLIGDRVEAVVSMIWIRSAL
SLDDALSAHSEALASIATAIARDVSAQQK

Specific function: Activator of the mhpRABCDEF operon coding for components of the 3-hydroxyphenylpropionate degradation pathway [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI145693096, Length=258, Percent_Identity=35.2713178294574, Blast_Score=127, Evalue=9e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 29857; Mature: 29726

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQRLADERATTPDRSDSVRALRRGLAVLRYINAVGSTNAASIARALDIPRPTVYRLLQT
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHH
LEEEGYVAFSASSTQVRVTRLSASLGDGYAAHSRVCQVAAPVFGEYGPRLVWPLDLTVYE
HHHCCEEEEECCCCEEEEEEEHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEC
NAAMVIHETTHTRSPLSIDRGMIGYRLPMLRTSAGRAYLAFCREEERAMILDHLRRIHDP
CCEEEEEECCCCCCCCCCCCCCHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
EDRPFLDEAWLGRMIEETRRRAVAVRDGGEFRPKTSSIAVPVLIGDRVEAVVSMIWIRSA
CCCCCHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHH
LSLDDALSAHSEALASIATAIARDVSAQQK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GQRLADERATTPDRSDSVRALRRGLAVLRYINAVGSTNAASIARALDIPRPTVYRLLQT
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHH
LEEEGYVAFSASSTQVRVTRLSASLGDGYAAHSRVCQVAAPVFGEYGPRLVWPLDLTVYE
HHHCCEEEEECCCCEEEEEEEHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEC
NAAMVIHETTHTRSPLSIDRGMIGYRLPMLRTSAGRAYLAFCREEERAMILDHLRRIHDP
CCEEEEEECCCCCCCCCCCCCCHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
EDRPFLDEAWLGRMIEETRRRAVAVRDGGEFRPKTSSIAVPVLIGDRVEAVVSMIWIRSA
CCCCCHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHH
LSLDDALSAHSEALASIATAIARDVSAQQK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]