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The map label for this gene is czcR [H]

Identifier: 154244582

GI number: 154244582

Start: 707363

End: 708241

Strand: Direct

Name: czcR [H]

Synonym: Xaut_0630

Alternate gene names: 154244582

Gene position: 707363-708241 (Clockwise)

Preceding gene: 154244580

Following gene: 154244584

Centisome position: 13.32

GC content: 70.76

Gene sequence:

>879_bases
ATGGACACCGAGTTCGTCAGGACCGCAATCACCGTCATCGAGGAGCGGTCCATCGCCGCTGCGGCGCGCCGGCTCGGCCT
GACTGCCGGGGCCGTGGCGCTCCGGATCAAGACGCTGGAGAGCGAGCTTGGCACGGTGCTGATCGGCCGGGCGGGGCGCA
GCATCGCGCCGACTGCTTCGGCGGCGCGGCTGCTGCCTGGGCTGCGAGCCATGGTCGACCAGGCCACCGACCTCCAGAGG
CGGGCCACCGCCAGCGGCGGCATCTCCGGCGAACTGCGGCTGGGCACCATCGCCACTGCCAGCACCGGGATTCTGCCGCC
GTTGCTGTGCACCCTCACGCAGCGTCATCCCGACCTGGACGTGATGATCGAGCCGGGAACCTCTCTCGACCTGTGCGAGC
GGGTGCTGGATGGTTCGCTTGACGCCGCCATTGTGGTCGAACCCCCTGCGCCTTTGCGCAAGGGCGAGCGCTTCAGCCCC
TGGGCCGTCGAACCGCTGGTGCTGATCGCACCCCCCGCCTGCGCTGGACGCGACCCCATTGCGCTGCTCTCCAGCGAGGC
CTTCATCCGCTACGACCGGCGCAATTGGGGCGGCCGGATCGTCGACCGCTTTCTGCGCACCACCGGGATCGTGGTGCGCG
AGCGGATTGAGCTGGATGCCCTGGACGGGATCGTGGCCATGGTCTCCGCCGGCCTCGGCGTGGCTATCATCCCGGACTGG
ACCGGGCCGCGCCTTGAAGGGGCGAAGGTGGTGAGCCTGCCGCTGCCGCCGCCCCAGCCGTCACGCACCATCGGCCTCTA
CAGCCGCACCCTGTCGATCCGGCAGGACCTGATCGCCCTGGTCGAGGACAGCCACCGCGCCGGCGCCGGCAGGGTGTGA

Upstream 100 bases:

>100_bases
AAGCGACATGGGGCGATCTCCTGTGCGGCCCCTTGCTACGCCAGGTCAATTGGCGATAAAAGCTGCTGATGTCTGACTTC
AGACATCAGGAAAACTGCGG

Downstream 100 bases:

>100_bases
CCGGTCGGGCACAATGGTTGCGTGTCACGGTGCGCCGGGCGAGACCCCGATGCGCTTTCGCCCGCTCAAGGCCAGGGGCT
TCAGCAGCTCGGCGCAGACA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MDTEFVRTAITVIEERSIAAAARRLGLTAGAVALRIKTLESELGTVLIGRAGRSIAPTASAARLLPGLRAMVDQATDLQR
RATASGGISGELRLGTIATASTGILPPLLCTLTQRHPDLDVMIEPGTSLDLCERVLDGSLDAAIVVEPPAPLRKGERFSP
WAVEPLVLIAPPACAGRDPIALLSSEAFIRYDRRNWGGRIVDRFLRTTGIVVRERIELDALDGIVAMVSAGLGVAIIPDW
TGPRLEGAKVVSLPLPPPQPSRTIGLYSRTLSIRQDLIALVEDSHRAGAGRV

Sequences:

>Translated_292_residues
MDTEFVRTAITVIEERSIAAAARRLGLTAGAVALRIKTLESELGTVLIGRAGRSIAPTASAARLLPGLRAMVDQATDLQR
RATASGGISGELRLGTIATASTGILPPLLCTLTQRHPDLDVMIEPGTSLDLCERVLDGSLDAAIVVEPPAPLRKGERFSP
WAVEPLVLIAPPACAGRDPIALLSSEAFIRYDRRNWGGRIVDRFLRTTGIVVRERIELDALDGIVAMVSAGLGVAIIPDW
TGPRLEGAKVVSLPLPPPQPSRTIGLYSRTLSIRQDLIALVEDSHRAGAGRV
>Mature_292_residues
MDTEFVRTAITVIEERSIAAAARRLGLTAGAVALRIKTLESELGTVLIGRAGRSIAPTASAARLLPGLRAMVDQATDLQR
RATASGGISGELRLGTIATASTGILPPLLCTLTQRHPDLDVMIEPGTSLDLCERVLDGSLDAAIVVEPPAPLRKGERFSP
WAVEPLVLIAPPACAGRDPIALLSSEAFIRYDRRNWGGRIVDRFLRTTGIVVRERIELDALDGIVAMVSAGLGVAIIPDW
TGPRLEGAKVVSLPLPPPQPSRTIGLYSRTLSIRQDLIALVEDSHRAGAGRV

Specific function: Hydrogen Peroxide Sensor. Activates The Expression Of A Regulon Of Hydrogen Peroxide-Inducible Genes Such As Katg, Gor, Ahpc, Ahpf, Oxys (A Regulatory RNA), Dps, Fur And Grxa. Oxyr Expression Is Negatively Autoregulated By Binding To A 43 Bp Region Upstre

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=276, Percent_Identity=26.4492753623188, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI2367136, Length=253, Percent_Identity=27.6679841897233, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI145693105, Length=274, Percent_Identity=25.9124087591241, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87082132, Length=269, Percent_Identity=26.0223048327138, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788297, Length=254, Percent_Identity=25.1968503937008, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1790208, Length=245, Percent_Identity=27.3469387755102, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1788481, Length=262, Percent_Identity=25.5725190839695, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788748, Length=258, Percent_Identity=25.5813953488372, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787879, Length=249, Percent_Identity=25.3012048192771, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1787589, Length=160, Percent_Identity=32.5, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31031; Mature: 31031

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTEFVRTAITVIEERSIAAAARRLGLTAGAVALRIKTLESELGTVLIGRAGRSIAPTAS
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEHHHHHHHHCEEEEECCCCCCCCCHH
AARLLPGLRAMVDQATDLQRRATASGGISGELRLGTIATASTGILPPLLCTLTQRHPDLD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCHHHHHHHHHCCCCCCE
VMIEPGTSLDLCERVLDGSLDAAIVVEPPAPLRKGERFSPWAVEPLVLIAPPACAGRDPI
EEECCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCC
ALLSSEAFIRYDRRNWGGRIVDRFLRTTGIVVRERIELDALDGIVAMVSAGLGVAIIPDW
EEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCC
TGPRLEGAKVVSLPLPPPQPSRTIGLYSRTLSIRQDLIALVEDSHRAGAGRV
CCCCCCCCEEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MDTEFVRTAITVIEERSIAAAARRLGLTAGAVALRIKTLESELGTVLIGRAGRSIAPTAS
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEHHHHHHHHCEEEEECCCCCCCCCHH
AARLLPGLRAMVDQATDLQRRATASGGISGELRLGTIATASTGILPPLLCTLTQRHPDLD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCHHHHHHHHHCCCCCCE
VMIEPGTSLDLCERVLDGSLDAAIVVEPPAPLRKGERFSPWAVEPLVLIAPPACAGRDPI
EEECCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCC
ALLSSEAFIRYDRRNWGGRIVDRFLRTTGIVVRERIELDALDGIVAMVSAGLGVAIIPDW
EEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCC
TGPRLEGAKVVSLPLPPPQPSRTIGLYSRTLSIRQDLIALVEDSHRAGAGRV
CCCCCCCCEEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA