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The map label for this gene is qor [H]

Identifier: 154244363

GI number: 154244363

Start: 436678

End: 437658

Strand: Direct

Name: qor [H]

Synonym: Xaut_0406

Alternate gene names: 154244363

Gene position: 436678-437658 (Clockwise)

Preceding gene: 154244359

Following gene: 154244368

Centisome position: 8.23

GC content: 70.44

Gene sequence:

>981_bases
ATGAAAGCGGTCGTCTGCGTGCGCCATGGTCCCCCCGACGCCCTCGAAATCCAGGATCTGCCTGATCCCGTGCCGGGGCC
GGGGGAGGTGGTGGTCGAGGTCTCGGCCATCGGGCTCAATTTCTTCGACACGCTGATCATCCGCGATCTCTACCAAGTCA
AGCCGGCCCTGCCGTTCTCGCCAGGCGCCGAGTTCGCCGGCCATGTGGCGGCGCTGGGCGCTGGCGTCACCGGCTTTGCC
GTAGGCGAGCGGGTGTGCGGCTATGTCACCCACGGCGCCGCGCGCGAGAAGGTGGTGGTGGAGGCCCGCTTCCTGGCGCG
GGTGCCGGACGACCTCGACCTGGTGAAGGCCGCCGGCCTCATCGTCACCTACGGCACCTCGCTCTATGCCCTGCGCGAGC
GCGGCAACCTGAAGGCGGGCGAGAGCCTCGCCGTCCTCGGCGCCTCGGGCGGGGTCGGGCTCGCGGCGGTGGAACTCGGG
CGCATCATGGGCGCGCGCATCCTCGCCTGCGCCTCGTCCGCCGAGAAGGTGGCCTTCGCCAAGGCCCACGGGGCGGACGA
GGGCTTCGACTATGCCGAGGGCGACCTCAAGGGCGCGCTCAAGGCGTTCGGCGGGCCCAAGGGTCTCGACATGGTCTATG
ATCCGGTGGGCGGCGACATGGCCGAGCAGGCTCTGCGGGCGCTCGGCTCCCTCGGCCGTTTCCTGGTGGTGGGGTTCGCC
GCCGGCGAAATCCCGAAGATCCCGCTCAACCTGTTGCTGCTGAAGAATTGCGACGCGCGCGGCGTGGCCTTCGGCACGGT
GGCGCGCAGTGATCCGGCGTGGCTTGCCGGCGTGGTGGCCGAACTGATGGAGCATGCGCGCACAGGCCGCATCTCCGCCC
ATGTGGACAAGACCTTCCCGCTGGAGCGCTGCGTCGATGCGCTGGGGGAGATCGCCGGGCGGCGCGTCAAGGGCAAGGTG
GTGCTCACCACCGGCCGCTGA

Upstream 100 bases:

>100_bases
GGCATGCCGCTGGGGAATGGATATGTATCCGGAGCTTTTGCGCCTCGGGGTTAAATTTTGGTAACCCGTCGCCCGATCCA
CCGTGACAGAAGGTGAGCCC

Downstream 100 bases:

>100_bases
CGGCTCGACGCCGGGATGCGGGCGCCCGGACGGTTCAGGCCGTCTCGTCTTTCAGGCGCCCCAGGGCGTCACGGGCGGCG
GTATAGTGCTCGGGCGTCAC

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MKAVVCVRHGPPDALEIQDLPDPVPGPGEVVVEVSAIGLNFFDTLIIRDLYQVKPALPFSPGAEFAGHVAALGAGVTGFA
VGERVCGYVTHGAAREKVVVEARFLARVPDDLDLVKAAGLIVTYGTSLYALRERGNLKAGESLAVLGASGGVGLAAVELG
RIMGARILACASSAEKVAFAKAHGADEGFDYAEGDLKGALKAFGGPKGLDMVYDPVGGDMAEQALRALGSLGRFLVVGFA
AGEIPKIPLNLLLLKNCDARGVAFGTVARSDPAWLAGVVAELMEHARTGRISAHVDKTFPLERCVDALGEIAGRRVKGKV
VLTTGR

Sequences:

>Translated_326_residues
MKAVVCVRHGPPDALEIQDLPDPVPGPGEVVVEVSAIGLNFFDTLIIRDLYQVKPALPFSPGAEFAGHVAALGAGVTGFA
VGERVCGYVTHGAAREKVVVEARFLARVPDDLDLVKAAGLIVTYGTSLYALRERGNLKAGESLAVLGASGGVGLAAVELG
RIMGARILACASSAEKVAFAKAHGADEGFDYAEGDLKGALKAFGGPKGLDMVYDPVGGDMAEQALRALGSLGRFLVVGFA
AGEIPKIPLNLLLLKNCDARGVAFGTVARSDPAWLAGVVAELMEHARTGRISAHVDKTFPLERCVDALGEIAGRRVKGKV
VLTTGR
>Mature_326_residues
MKAVVCVRHGPPDALEIQDLPDPVPGPGEVVVEVSAIGLNFFDTLIIRDLYQVKPALPFSPGAEFAGHVAALGAGVTGFA
VGERVCGYVTHGAAREKVVVEARFLARVPDDLDLVKAAGLIVTYGTSLYALRERGNLKAGESLAVLGASGGVGLAAVELG
RIMGARILACASSAEKVAFAKAHGADEGFDYAEGDLKGALKAFGGPKGLDMVYDPVGGDMAEQALRALGSLGRFLVVGFA
AGEIPKIPLNLLLLKNCDARGVAFGTVARSDPAWLAGVVAELMEHARTGRISAHVDKTFPLERCVDALGEIAGRRVKGKV
VLTTGR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI18379349, Length=312, Percent_Identity=31.4102564102564, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI194239674, Length=325, Percent_Identity=30.7692307692308, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI13236495, Length=325, Percent_Identity=30.7692307692308, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI22538446, Length=332, Percent_Identity=29.5180722891566, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI22538444, Length=332, Percent_Identity=29.5180722891566, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI194239676, Length=206, Percent_Identity=34.4660194174757, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI24308257, Length=343, Percent_Identity=28.2798833819242, Blast_Score=111, Evalue=8e-25,
Organism=Homo sapiens, GI28557745, Length=250, Percent_Identity=34.8, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI41872631, Length=304, Percent_Identity=28.2894736842105, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI67078404, Length=333, Percent_Identity=24.9249249249249, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI47519420, Length=370, Percent_Identity=25.4054054054054, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI197927207, Length=187, Percent_Identity=31.0160427807487, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI67078406, Length=294, Percent_Identity=24.8299319727891, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1790485, Length=249, Percent_Identity=32.9317269076305, Blast_Score=110, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17507255, Length=323, Percent_Identity=28.1733746130031, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17556000, Length=341, Percent_Identity=25.5131964809384, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17536829, Length=258, Percent_Identity=27.5193798449612, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=328, Percent_Identity=28.9634146341463, Blast_Score=121, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6323729, Length=293, Percent_Identity=25.2559726962457, Blast_Score=76, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6323961, Length=259, Percent_Identity=27.027027027027, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324486, Length=259, Percent_Identity=27.7992277992278, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319621, Length=215, Percent_Identity=26.046511627907, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI221330659, Length=268, Percent_Identity=26.1194029850746, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI19920632, Length=268, Percent_Identity=26.1194029850746, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI45550423, Length=321, Percent_Identity=25.2336448598131, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 33791; Mature: 33791

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVVCVRHGPPDALEIQDLPDPVPGPGEVVVEVSAIGLNFFDTLIIRDLYQVKPALPFS
CCEEEEEECCCCCCEEECCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCCC
PGAEFAGHVAALGAGVTGFAVGERVCGYVTHGAAREKVVVEARFLARVPDDLDLVKAAGL
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHCCCCHHHHHHCCE
IVTYGTSLYALRERGNLKAGESLAVLGASGGVGLAAVELGRIMGARILACASSAEKVAFA
EEEECCCEEEEHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCHHEEEH
KAHGADEGFDYAEGDLKGALKAFGGPKGLDMVYDPVGGDMAEQALRALGSLGRFLVVGFA
HHCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCEEEEEEC
AGEIPKIPLNLLLLKNCDARGVAFGTVARSDPAWLAGVVAELMEHARTGRISAHVDKTFP
CCCCCCCCEEEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCC
LERCVDALGEIAGRRVKGKVVLTTGR
HHHHHHHHHHHHCCEEECEEEEEECC
>Mature Secondary Structure
MKAVVCVRHGPPDALEIQDLPDPVPGPGEVVVEVSAIGLNFFDTLIIRDLYQVKPALPFS
CCEEEEEECCCCCCEEECCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCCC
PGAEFAGHVAALGAGVTGFAVGERVCGYVTHGAAREKVVVEARFLARVPDDLDLVKAAGL
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHCCCCHHHHHHCCE
IVTYGTSLYALRERGNLKAGESLAVLGASGGVGLAAVELGRIMGARILACASSAEKVAFA
EEEECCCEEEEHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCHHEEEH
KAHGADEGFDYAEGDLKGALKAFGGPKGLDMVYDPVGGDMAEQALRALGSLGRFLVVGFA
HHCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCEEEEEEC
AGEIPKIPLNLLLLKNCDARGVAFGTVARSDPAWLAGVVAELMEHARTGRISAHVDKTFP
CCCCCCCCEEEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCC
LERCVDALGEIAGRRVKGKVVLTTGR
HHHHHHHHHHHHCCEEECEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]