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The map label for this gene is murB

Identifier: 154244281

GI number: 154244281

Start: 334428

End: 335465

Strand: Direct

Name: murB

Synonym: Xaut_0324

Alternate gene names: 154244281

Gene position: 334428-335465 (Clockwise)

Preceding gene: 154244279

Following gene: 154244282

Centisome position: 6.3

GC content: 70.71

Gene sequence:

>1038_bases
ATGGCGGCCCGGCAAAAGCCGGCGATGCTTGCCCTCGCGACCCTGTTATGGGAGAGCGACCCCTATGATGGACGGACAGG
CAGGATGAGCGTGGCACAGACACACCCGGCGGGGCAGGGCTTCGAGGACCTGGTCCCCGGCCTCAAGGCGCGCCTTCCGG
GATTGCGCGGCTCCCTGAAGGCCAACGCGCCGCTCGCCGAATTCACCTGGTTCCGGGCCGGCGGTCCGGCACAGGTGCTG
TTCGTGCCGGCGGACGAGGATGACCTCGCCACTTTCCTCGCCGGCCTGCCGGCGGAGGTGCCGGTGACCGTCATTGGCCT
CGGCTCCAACCTCATCGTGCGCGATGGCGGGGTGCCGGGGGTGGTGATCCGCCTTGCCCGCGGCTTCACGGATATCGCGG
TGGAAGGCAACCGCATCATCGCCGGCGCCGGCGTGCCGGACGTGAAGGTGGCGCGGGCGGCGGCCGATGCGGGGCTTGCC
GGCTTCTCCTTCCTGCGCGGCATTCCCGGTGCCGTGGGCGGCGCCCTGCGCATGAATGGCGGCGCCTATGGCGGCGAGAC
CAAGGATGTTCTGGTCAGCGCCGACGCCGTGACCCGAGCCGGCGCGAAGGTGCGCTTCACCAATGCCGAGATGGGCTTCA
CCTACCGCCATTGCGGCGTGCCGGCGGACGTGGTCTTCACCCGCGCCGTGTTCGAGGGCCGGCCCGGCGATCCGGCGGTG
ATCGCCGCCGAGATGGCGAAGATCACCGAAAGCCGGGAGGCGACCCAGCCCATCAAGAGCCGCACCGGCGGTTCCACCTT
CAAGAACCCGCCCGGCACCAGCGCCTGGAAGCTGGTGGACGCCGCCGGCTGCCGCGGCCTCACCATCGGCCGGGCGCAGG
TGTCCGAGCTGCACACCAACTTCCTCATCAATCTGGGCGGCGCCACCGCCGCCGAGATCGAGGGGCTGGGCGAGGAAGTG
CGCCGCCGGGTGAAGGCCCAGTGCGGCATCGAGCTGGAGTGGGAAATCAAGCGCATCGGCCTGCCTGCGGCGTCCTGA

Upstream 100 bases:

>100_bases
GCAGGGCCGGATCAGAGCCGATGTCGCTGTGAATGTCTTCGCTCATGGGGGCAGCTCCAGGCGAAAGGGAAGGGCGAATG
GTTCGCCATGATGCCACGTC

Downstream 100 bases:

>100_bases
GCGGGCCATTAGCAAAGGCGCAAGGCAATGGCGCCATCTTGAGGCGCCATTTGGGGCACTGGGCAGGAGCGTCATCGGGC
GCGCGGCCGAGCCGTGGATA

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MAARQKPAMLALATLLWESDPYDGRTGRMSVAQTHPAGQGFEDLVPGLKARLPGLRGSLKANAPLAEFTWFRAGGPAQVL
FVPADEDDLATFLAGLPAEVPVTVIGLGSNLIVRDGGVPGVVIRLARGFTDIAVEGNRIIAGAGVPDVKVARAAADAGLA
GFSFLRGIPGAVGGALRMNGGAYGGETKDVLVSADAVTRAGAKVRFTNAEMGFTYRHCGVPADVVFTRAVFEGRPGDPAV
IAAEMAKITESREATQPIKSRTGGSTFKNPPGTSAWKLVDAAGCRGLTIGRAQVSELHTNFLINLGGATAAEIEGLGEEV
RRRVKAQCGIELEWEIKRIGLPAAS

Sequences:

>Translated_345_residues
MAARQKPAMLALATLLWESDPYDGRTGRMSVAQTHPAGQGFEDLVPGLKARLPGLRGSLKANAPLAEFTWFRAGGPAQVL
FVPADEDDLATFLAGLPAEVPVTVIGLGSNLIVRDGGVPGVVIRLARGFTDIAVEGNRIIAGAGVPDVKVARAAADAGLA
GFSFLRGIPGAVGGALRMNGGAYGGETKDVLVSADAVTRAGAKVRFTNAEMGFTYRHCGVPADVVFTRAVFEGRPGDPAV
IAAEMAKITESREATQPIKSRTGGSTFKNPPGTSAWKLVDAAGCRGLTIGRAQVSELHTNFLINLGGATAAEIEGLGEEV
RRRVKAQCGIELEWEIKRIGLPAAS
>Mature_344_residues
AARQKPAMLALATLLWESDPYDGRTGRMSVAQTHPAGQGFEDLVPGLKARLPGLRGSLKANAPLAEFTWFRAGGPAQVLF
VPADEDDLATFLAGLPAEVPVTVIGLGSNLIVRDGGVPGVVIRLARGFTDIAVEGNRIIAGAGVPDVKVARAAADAGLAG
FSFLRGIPGAVGGALRMNGGAYGGETKDVLVSADAVTRAGAKVRFTNAEMGFTYRHCGVPADVVFTRAVFEGRPGDPAVI
AAEMAKITESREATQPIKSRTGGSTFKNPPGTSAWKLVDAAGCRGLTIGRAQVSELHTNFLINLGGATAAEIEGLGEEVR
RRVKAQCGIELEWEIKRIGLPAAS

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 35835; Mature: 35704

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAARQKPAMLALATLLWESDPYDGRTGRMSVAQTHPAGQGFEDLVPGLKARLPGLRGSLK
CCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCHHHHHCHHHHHCCCCCCCCC
ANAPLAEFTWFRAGGPAQVLFVPADEDDLATFLAGLPAEVPVTVIGLGSNLIVRDGGVPG
CCCCHHHEEEEECCCCEEEEEEECCCHHHHHHHHCCCCCCCEEEEEECCCEEEECCCCCH
VVIRLARGFTDIAVEGNRIIAGAGVPDVKVARAAADAGLAGFSFLRGIPGAVGGALRMNG
HHHHHHCCCEEEEEECCEEEEECCCCCHHHHHHHHHCCHHHHHHHHCCCCCCCCEEEECC
GAYGGETKDVLVSADAVTRAGAKVRFTNAEMGFTYRHCGVPADVVFTRAVFEGRPGDPAV
CCCCCCCCEEEEECHHHHHCCCEEEEECCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCE
IAAEMAKITESREATQPIKSRTGGSTFKNPPGTSAWKLVDAAGCRGLTIGRAQVSELHTN
EHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEHHCCCCCEEECHHHHHHHHCE
FLINLGGATAAEIEGLGEEVRRRVKAQCGIELEWEIKRIGLPAAS
EEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCC
>Mature Secondary Structure 
AARQKPAMLALATLLWESDPYDGRTGRMSVAQTHPAGQGFEDLVPGLKARLPGLRGSLK
CCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCHHHHHCHHHHHCCCCCCCCC
ANAPLAEFTWFRAGGPAQVLFVPADEDDLATFLAGLPAEVPVTVIGLGSNLIVRDGGVPG
CCCCHHHEEEEECCCCEEEEEEECCCHHHHHHHHCCCCCCCEEEEEECCCEEEECCCCCH
VVIRLARGFTDIAVEGNRIIAGAGVPDVKVARAAADAGLAGFSFLRGIPGAVGGALRMNG
HHHHHHCCCEEEEEECCEEEEECCCCCHHHHHHHHHCCHHHHHHHHCCCCCCCCEEEECC
GAYGGETKDVLVSADAVTRAGAKVRFTNAEMGFTYRHCGVPADVVFTRAVFEGRPGDPAV
CCCCCCCCEEEEECHHHHHCCCEEEEECCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCE
IAAEMAKITESREATQPIKSRTGGSTFKNPPGTSAWKLVDAAGCRGLTIGRAQVSELHTN
EHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEHHCCCCCEEECHHHHHHHHCE
FLINLGGATAAEIEGLGEEVRRRVKAQCGIELEWEIKRIGLPAAS
EEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA