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The map label for this gene is aroA [H]

Identifier: 153951777

GI number: 153951777

Start: 814393

End: 815664

Strand: Direct

Name: aroA [H]

Synonym: JJD26997_0918

Alternate gene names: 153951777

Gene position: 814393-815664 (Clockwise)

Preceding gene: 153952099

Following gene: 153952263

Centisome position: 44.14

GC content: 30.97

Gene sequence:

>1272_bases
TTGCAAACCCCTGTAAATACTATACTTGAAAATATAGCAGCAGATAAAAGCATATCTCATCGTTTTGCCATATTTTCGCT
TTTAACACAAGGAGAAAATAAGGCTCGAAATTATCTCTTAGCTCAAGATACTTTAAATACTCTTGAGATTATAAAAAATC
TTGGAGCTAAAATTGAACAAAAAGATTCTTGCGTCAAAATTATACCCCCTAAAGAAATTTTATCTCCAAATTGTATTTTA
GACTGTGGAAATTCAGGAACTGCTATGCGTTTGATGATAGGATTTTTAGCAGGAATTTCTGGTTTTTTTGTTTTAAGTGG
AGATAAGTTTTTAAACAATCGTCCTATGAGAAGGATAAGCAAACCACTTACTCAAATAGGAGCTAGAATTTATGGAAGAA
ATGAGGCAAATTTAGCTCCACTTTGTATAGAAGGTCAAAATTTAAAAGCTTTTAATTATAAAAGCGAAATTTCTTCGGCT
CAAGTTAAAACAGCTATGATTTTATCTGCTTTTAGAGCTGATAATATATGCACTTTTAGTGAAATTTCTCTTAGTAGAAA
TCATAGTGAAAACATGTTAAAGGCTATGAAAGCTCCAATGAGGGTTAGTAATGATGGCTTAAATCTTGAAATAAGTCCTT
TAAAAAAACCCTTAAAAGCTCAAAATATAATCATTCCTAATGATCCTTCTTCGGCTTTTTATTTTGCTTTAGCAGCTATT
ATTTTGCCTAAATCTCAAATTATTTTAAAAAATATTTTACTTAATCCTACTCGTATAGAGGCGTATAAAATTTTGCAAAA
AATGGGTGCAAAACTTGAAATGACAATAACTCAAAATGATTTTGAAACTATTGGTGAGATCAGAGTAGAGTCTAGCAAGC
TTAATGGCATAGAAGTTAAAGATAATATCGCTTGGCTGATAGATGAAGCACCTGCTTTGGCTATAGCTTTTGCTTTAGCT
AAGGGTAAATCTAATTTAGTAAATGCTAAAGAATTACGCGTTAAAGAAAGCGATAGGATTGCTGTGATGGTTGAAAATCT
AAAGCTTTGTGGTGTTGAAGCTAAAGAATTTGATGATGGTTTTGAAATAGAAGGTGGATGCGAACTTAAATCTTCAAAAA
TTAAAAGCTATGGAGATCACCGTATTGCTATGAGTTTTGCTATTTTAGGTTTGCTTTGTGGAATTGAGATTGATGATAGT
GATTGTATAAAAACTTCTTTTCCAAATTTTATAGAGATTTTATCAAATTTAGGAGCTAGGATTGATTATTGA

Upstream 100 bases:

>100_bases
TAAATAAAACTCTAGAAGATAATCAAGTAAATGAATGCATGGATAAAATTTTAAATACTCTTAAAAATTTGGGGCTTGAT
TTAAGATGAAAATTTATAAA

Downstream 100 bases:

>100_bases
ATTAGCAAAAAATTATGGTTTTTGTTTTGGTGTTAAAAGGGCTATTAAAAAAGCAGAACAAATAAAAGATGCCGCAACTA
TAGGCCCTCTTATTCATAAC

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MQTPVNTILENIAADKSISHRFAIFSLLTQGENKARNYLLAQDTLNTLEIIKNLGAKIEQKDSCVKIIPPKEILSPNCIL
DCGNSGTAMRLMIGFLAGISGFFVLSGDKFLNNRPMRRISKPLTQIGARIYGRNEANLAPLCIEGQNLKAFNYKSEISSA
QVKTAMILSAFRADNICTFSEISLSRNHSENMLKAMKAPMRVSNDGLNLEISPLKKPLKAQNIIIPNDPSSAFYFALAAI
ILPKSQIILKNILLNPTRIEAYKILQKMGAKLEMTITQNDFETIGEIRVESSKLNGIEVKDNIAWLIDEAPALAIAFALA
KGKSNLVNAKELRVKESDRIAVMVENLKLCGVEAKEFDDGFEIEGGCELKSSKIKSYGDHRIAMSFAILGLLCGIEIDDS
DCIKTSFPNFIEILSNLGARIDY

Sequences:

>Translated_423_residues
MQTPVNTILENIAADKSISHRFAIFSLLTQGENKARNYLLAQDTLNTLEIIKNLGAKIEQKDSCVKIIPPKEILSPNCIL
DCGNSGTAMRLMIGFLAGISGFFVLSGDKFLNNRPMRRISKPLTQIGARIYGRNEANLAPLCIEGQNLKAFNYKSEISSA
QVKTAMILSAFRADNICTFSEISLSRNHSENMLKAMKAPMRVSNDGLNLEISPLKKPLKAQNIIIPNDPSSAFYFALAAI
ILPKSQIILKNILLNPTRIEAYKILQKMGAKLEMTITQNDFETIGEIRVESSKLNGIEVKDNIAWLIDEAPALAIAFALA
KGKSNLVNAKELRVKESDRIAVMVENLKLCGVEAKEFDDGFEIEGGCELKSSKIKSYGDHRIAMSFAILGLLCGIEIDDS
DCIKTSFPNFIEILSNLGARIDY
>Mature_423_residues
MQTPVNTILENIAADKSISHRFAIFSLLTQGENKARNYLLAQDTLNTLEIIKNLGAKIEQKDSCVKIIPPKEILSPNCIL
DCGNSGTAMRLMIGFLAGISGFFVLSGDKFLNNRPMRRISKPLTQIGARIYGRNEANLAPLCIEGQNLKAFNYKSEISSA
QVKTAMILSAFRADNICTFSEISLSRNHSENMLKAMKAPMRVSNDGLNLEISPLKKPLKAQNIIIPNDPSSAFYFALAAI
ILPKSQIILKNILLNPTRIEAYKILQKMGAKLEMTITQNDFETIGEIRVESSKLNGIEVKDNIAWLIDEAPALAIAFALA
KGKSNLVNAKELRVKESDRIAVMVENLKLCGVEAKEFDDGFEIEGGCELKSSKIKSYGDHRIAMSFAILGLLCGIEIDDS
DCIKTSFPNFIEILSNLGARIDY

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=420, Percent_Identity=28.0952380952381, Blast_Score=108, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6320332, Length=463, Percent_Identity=23.9740820734341, Blast_Score=91, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 46638; Mature: 46638

Theoretical pI: Translated: 8.30; Mature: 8.30

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTPVNTILENIAADKSISHRFAIFSLLTQGENKARNYLLAQDTLNTLEIIKNLGAKIEQ
CCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHCEEEEHHHHHHHHHHHHHCCCCCC
KDSCVKIIPPKEILSPNCILDCGNSGTAMRLMIGFLAGISGFFVLSGDKFLNNRPMRRIS
CCCEEEEECCHHHCCCCEEEECCCCCHHHHHHHHHHHHCCEEEEEECCHHHCCCCHHHHH
KPLTQIGARIYGRNEANLAPLCIEGQNLKAFNYKSEISSAQVKTAMILSAFRADNICTFS
HHHHHHHHHEECCCCCCCCEEEEECCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEH
EISLSRNHSENMLKAMKAPMRVSNDGLNLEISPLKKPLKAQNIIIPNDPSSAFYFALAAI
HHHCCCCCHHHHHHHHHCCCEECCCCCEEEEHHHCCCCCCCCEEECCCCCHHHHHHHHHH
ILPKSQIILKNILLNPTRIEAYKILQKMGAKLEMTITQNDFETIGEIRVESSKLNGIEVK
HCCCHHHHHHHHHCCCHHHHHHHHHHHHCCEEEEEEECCCHHHHHHEEEECCCCCCEEEE
DNIAWLIDEAPALAIAFALAKGKSNLVNAKELRVKESDRIAVMVENLKLCGVEAKEFDDG
CCEEEEECCCCHHHHHHHHHCCCCCCCCHHHHEECCCCCEEEEEECCEEECCCHHHCCCC
FEIEGGCELKSSKIKSYGDHRIAMSFAILGLLCGIEIDDSDCIKTSFPNFIEILSNLGAR
CCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHCCCHHHHHHHHHCCCC
IDY
CCC
>Mature Secondary Structure
MQTPVNTILENIAADKSISHRFAIFSLLTQGENKARNYLLAQDTLNTLEIIKNLGAKIEQ
CCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHCEEEEHHHHHHHHHHHHHCCCCCC
KDSCVKIIPPKEILSPNCILDCGNSGTAMRLMIGFLAGISGFFVLSGDKFLNNRPMRRIS
CCCEEEEECCHHHCCCCEEEECCCCCHHHHHHHHHHHHCCEEEEEECCHHHCCCCHHHHH
KPLTQIGARIYGRNEANLAPLCIEGQNLKAFNYKSEISSAQVKTAMILSAFRADNICTFS
HHHHHHHHHEECCCCCCCCEEEEECCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEH
EISLSRNHSENMLKAMKAPMRVSNDGLNLEISPLKKPLKAQNIIIPNDPSSAFYFALAAI
HHHCCCCCHHHHHHHHHCCCEECCCCCEEEEHHHCCCCCCCCEEECCCCCHHHHHHHHHH
ILPKSQIILKNILLNPTRIEAYKILQKMGAKLEMTITQNDFETIGEIRVESSKLNGIEVK
HCCCHHHHHHHHHCCCHHHHHHHHHHHHCCEEEEEEECCCHHHHHHEEEECCCCCCEEEE
DNIAWLIDEAPALAIAFALAKGKSNLVNAKELRVKESDRIAVMVENLKLCGVEAKEFDDG
CCEEEEECCCCHHHHHHHHHCCCCCCCCHHHHEECCCCCEEEEEECCEEECCCHHHCCCC
FEIEGGCELKSSKIKSYGDHRIAMSFAILGLLCGIEIDDSDCIKTSFPNFIEILSNLGAR
CCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHCCCHHHHHHHHHCCCC
IDY
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8973316 [H]