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The map label for this gene is ispH [H]

Identifier: 153952263

GI number: 153952263

Start: 815654

End: 816487

Strand: Direct

Name: ispH [H]

Synonym: JJD26997_0919

Alternate gene names: 153952263

Gene position: 815654-816487 (Clockwise)

Preceding gene: 153951777

Following gene: 153951138

Centisome position: 44.21

GC content: 29.74

Gene sequence:

>834_bases
TTGATTATTGAATTAGCAAAAAATTATGGTTTTTGTTTTGGTGTTAAAAGGGCTATTAAAAAAGCAGAACAAATAAAAGA
TGCCGCAACTATAGGCCCTCTTATTCATAACAATGAAGAAATTTCTCGTTTACAGAAAAATTTTAATGTCAAAACTTTAG
AAAATATAAAGTCTTTAAGCAATGAAACAAAGGCTATTATAAGAACCCACGGTATTACAAAGCAAGATTTAGAAGAATTG
AGAAAAAAAGATATAGAAATTTTTGACGCTACTTGTCCTTTTGTTACAAAACCACAACAAATTTGTGAACAAATGAGCAA
GGAGGGTTATGAAATTGTTATTTTTGGAGATGAAAATCATCCTGAAGTTAAAGGAGTAAAAAGCTATGTAAACACAAAAG
CTTATGTAGTTTTAGATAAAAAAGAACTGCAAAATATAAAACTTCCCAGTAAAATAGCCGTAGTAAGCCAAACAACTAAA
AAGCCTGAACATTTTATGGAGATAGTAAATTTTTTAATGCTTAAAGCCAAAGAAGTGAGAGTTTTTAACACTATATGTGA
TGCAACCTTTAAAAATCAAGATGCCATCAAAGAACTTTCACTTAAAAGCGATGTTATGGTTGTTGTAGGAGGTAAAAACT
CAGCCAATACAAAACAACTTTTTTTGATTGCGAAAACCAATTGTGAAGATAGTTATCTAATTGAAACTGAAGAAGAGTTG
AAAAAAGAATGGTTTTTAGATAAAAAACATTGCGGCATTAGCGCAGGTGCTAGCACTCCTGATTGGATCATACAAAAAGT
TATTGCCAAAATAGAAAATTTTGGAATTAATTAA

Upstream 100 bases:

>100_bases
ATTTTAGGTTTGCTTTGTGGAATTGAGATTGATGATAGTGATTGTATAAAAACTTCTTTTCCAAATTTTATAGAGATTTT
ATCAAATTTAGGAGCTAGGA

Downstream 100 bases:

>100_bases
AAAATGTTTTCATATAGAAAAAAGTCAAAAATTTAAAAAAAATTAACAAAAATAAAAAAAACTTAACACTAGTTAAAGAA
AAATAAGGTAAAATCAATCA

Product: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MIIELAKNYGFCFGVKRAIKKAEQIKDAATIGPLIHNNEEISRLQKNFNVKTLENIKSLSNETKAIIRTHGITKQDLEEL
RKKDIEIFDATCPFVTKPQQICEQMSKEGYEIVIFGDENHPEVKGVKSYVNTKAYVVLDKKELQNIKLPSKIAVVSQTTK
KPEHFMEIVNFLMLKAKEVRVFNTICDATFKNQDAIKELSLKSDVMVVVGGKNSANTKQLFLIAKTNCEDSYLIETEEEL
KKEWFLDKKHCGISAGASTPDWIIQKVIAKIENFGIN

Sequences:

>Translated_277_residues
MIIELAKNYGFCFGVKRAIKKAEQIKDAATIGPLIHNNEEISRLQKNFNVKTLENIKSLSNETKAIIRTHGITKQDLEEL
RKKDIEIFDATCPFVTKPQQICEQMSKEGYEIVIFGDENHPEVKGVKSYVNTKAYVVLDKKELQNIKLPSKIAVVSQTTK
KPEHFMEIVNFLMLKAKEVRVFNTICDATFKNQDAIKELSLKSDVMVVVGGKNSANTKQLFLIAKTNCEDSYLIETEEEL
KKEWFLDKKHCGISAGASTPDWIIQKVIAKIENFGIN
>Mature_277_residues
MIIELAKNYGFCFGVKRAIKKAEQIKDAATIGPLIHNNEEISRLQKNFNVKTLENIKSLSNETKAIIRTHGITKQDLEEL
RKKDIEIFDATCPFVTKPQQICEQMSKEGYEIVIFGDENHPEVKGVKSYVNTKAYVVLDKKELQNIKLPSKIAVVSQTTK
KPEHFMEIVNFLMLKAKEVRVFNTICDATFKNQDAIKELSLKSDVMVVVGGKNSANTKQLFLIAKTNCEDSYLIETEEEL
KKEWFLDKKHCGISAGASTPDWIIQKVIAKIENFGIN

Specific function: Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) [H]

COG id: COG0761

COG function: function code IM; Penicillin tolerance protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ispH family [H]

Homologues:

Organism=Escherichia coli, GI1786212, Length=288, Percent_Identity=29.8611111111111, Blast_Score=138, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003451 [H]

Pfam domain/function: PF02401 LYTB [H]

EC number: =1.17.1.2 [H]

Molecular weight: Translated: 31443; Mature: 31443

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIELAKNYGFCFGVKRAIKKAEQIKDAATIGPLIHNNEEISRLQKNFNVKTLENIKSLS
CEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHCCCHHHHHHHHHHH
NETKAIIRTHGITKQDLEELRKKDIEIFDATCPFVTKPQQICEQMSKEGYEIVIFGDENH
HHHHHHHHHCCCCHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHCCCEEEEECCCCC
PEVKGVKSYVNTKAYVVLDKKELQNIKLPSKIAVVSQTTKKPEHFMEIVNFLMLKAKEVR
CHHHHHHHHHCCEEEEEEEHHHHHCCCCCCCEEEHHHCCCCHHHHHHHHHHHHHHHHHHH
VFNTICDATFKNQDAIKELSLKSDVMVVVGGKNSANTKQLFLIAKTNCEDSYLIETEEEL
HHHHHHHHHCCCHHHHHHHCCCCCEEEEECCCCCCCCEEEEEEEECCCCCCEEECCHHHH
KKEWFLDKKHCGISAGASTPDWIIQKVIAKIENFGIN
HHHHCCCHHCCCCCCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIIELAKNYGFCFGVKRAIKKAEQIKDAATIGPLIHNNEEISRLQKNFNVKTLENIKSLS
CEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHCCCHHHHHHHHHHH
NETKAIIRTHGITKQDLEELRKKDIEIFDATCPFVTKPQQICEQMSKEGYEIVIFGDENH
HHHHHHHHHCCCCHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHCCCEEEEECCCCC
PEVKGVKSYVNTKAYVVLDKKELQNIKLPSKIAVVSQTTKKPEHFMEIVNFLMLKAKEVR
CHHHHHHHHHCCEEEEEEEHHHHHCCCCCCCEEEHHHCCCCHHHHHHHHHHHHHHHHHHH
VFNTICDATFKNQDAIKELSLKSDVMVVVGGKNSANTKQLFLIAKTNCEDSYLIETEEEL
HHHHHHHHHCCCHHHHHHHCCCCCEEEEECCCCCCCCEEEEEEEECCCCCCEEECCHHHH
KKEWFLDKKHCGISAGASTPDWIIQKVIAKIENFGIN
HHHHCCCHHCCCCCCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA