Click here to switch to the map view.

The map label for this gene is kdgR [H]

Identifier: 153951454

GI number: 153951454

Start: 1290176

End: 1290937

Strand: Direct

Name: kdgR [H]

Synonym: JJD26997_1454

Alternate gene names: 153951454

Gene position: 1290176-1290937 (Clockwise)

Preceding gene: 153951990

Following gene: 153952285

Centisome position: 69.92

GC content: 23.88

Gene sequence:

>762_bases
ATGCATCAGCCCACTCTTAGAGTGTTAAATATTCTAGAATTACTTGCAAAAGAAAAGCTTACCTTAAGTACTATAGCTAA
AAAACTAAACATTCCTGCTGGAACTCTTTGGCCTATCTTACAAACTCTTCAAGAAAAAAAATATATCAAATGTGATTTAA
AAAATAAAAGTTATTATTTGGATTTTAAGATTATAGAATTAGGATGTAATATAAAAAACGAAAATAATATTTTTGAAATA
ATCAAAAAGCATATGAAAAATATAAGAAATTTAACCAATCAAACTTGTCAAATGGGAATTTTAAAAGATGGAAATGTGCT
TTATTTAGAAAAAATTGATGCCAATAATACGGTGCAATTAAAATCTTTTATAGGCACTTCGTATCCTGCTTATGCAACAT
CTTTAGGCAAAGCCTTACTATCAAACAAAAATAAAAAGGAATTAGAAAAACTTTATCCTAACAATTTTGATAAAATTACA
GAAAACACCTTAAATAATATAAATGAACTCTATCAACAAATCAAACAAATTAAAAAAGAAAAAATTGCCATAGAAATTGG
AGAAATGAATCCTCAAATTGAATGTATGGCTATAGGCATAGAACATAAAAATAAAATAATTGCTGCCATTAGCATATCTT
ATCTAATTTATTGCTCTAATAAAACTTTTAGAGAAAAAAATAAAAAAATACTTCTAGAAGAAAAAAATAAAATAGAAAAA
GTTTTAAAAATTTATTTTAATGATTTAGATACACTGTATTAA

Upstream 100 bases:

>100_bases
AAAATATTAAAATTAATAAATAATAAAAATTATGATTTTATGTTACTAAAAGTAAAAAATATGCTAAAATTTATAAAAAT
AAAACAAGGATAAAGACAAT

Downstream 100 bases:

>100_bases
TATAGCCCCAAAGGGCTATAAAATAGAATTTTATTCTTGTTCTTTAAGTTTTAAATTTTGTTCACCATAAAGCCCTGTTC
CAACAGGTATCATTCTACCT

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MHQPTLRVLNILELLAKEKLTLSTIAKKLNIPAGTLWPILQTLQEKKYIKCDLKNKSYYLDFKIIELGCNIKNENNIFEI
IKKHMKNIRNLTNQTCQMGILKDGNVLYLEKIDANNTVQLKSFIGTSYPAYATSLGKALLSNKNKKELEKLYPNNFDKIT
ENTLNNINELYQQIKQIKKEKIAIEIGEMNPQIECMAIGIEHKNKIIAAISISYLIYCSNKTFREKNKKILLEEKNKIEK
VLKIYFNDLDTLY

Sequences:

>Translated_253_residues
MHQPTLRVLNILELLAKEKLTLSTIAKKLNIPAGTLWPILQTLQEKKYIKCDLKNKSYYLDFKIIELGCNIKNENNIFEI
IKKHMKNIRNLTNQTCQMGILKDGNVLYLEKIDANNTVQLKSFIGTSYPAYATSLGKALLSNKNKKELEKLYPNNFDKIT
ENTLNNINELYQQIKQIKKEKIAIEIGEMNPQIECMAIGIEHKNKIIAAISISYLIYCSNKTFREKNKKILLEEKNKIEK
VLKIYFNDLDTLY
>Mature_253_residues
MHQPTLRVLNILELLAKEKLTLSTIAKKLNIPAGTLWPILQTLQEKKYIKCDLKNKSYYLDFKIIELGCNIKNENNIFEI
IKKHMKNIRNLTNQTCQMGILKDGNVLYLEKIDANNTVQLKSFIGTSYPAYATSLGKALLSNKNKKELEKLYPNNFDKIT
ENTLNNINELYQQIKQIKKEKIAIEIGEMNPQIECMAIGIEHKNKIIAAISISYLIYCSNKTFREKNKKILLEEKNKIEK
VLKIYFNDLDTLY

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=212, Percent_Identity=24.0566037735849, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1786468, Length=232, Percent_Identity=28.448275862069, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788581, Length=213, Percent_Identity=23.0046948356808, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790752, Length=173, Percent_Identity=30.0578034682081, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789999, Length=218, Percent_Identity=20.6422018348624, Blast_Score=60, Evalue=1e-10,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 29362; Mature: 29362

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHQPTLRVLNILELLAKEKLTLSTIAKKLNIPAGTLWPILQTLQEKKYIKCDLKNKSYYL
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCEEEEEECCCEEEE
DFKIIELGCNIKNENNIFEIIKKHMKNIRNLTNQTCQMGILKDGNVLYLEKIDANNTVQL
EEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEECCCEEEEEEECCCCEEEE
KSFIGTSYPAYATSLGKALLSNKNKKELEKLYPNNFDKITENTLNNINELYQQIKQIKKE
HHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KIAIEIGEMNPQIECMAIGIEHKNKIIAAISISYLIYCSNKTFREKNKKILLEEKNKIEK
HEEEEECCCCCCEEEEEEEECCCCCEEEEEEEEEEEEECCCHHHHCCCEEEEHHHHHHHH
VLKIYFNDLDTLY
HHHHHHHHHHHCC
>Mature Secondary Structure
MHQPTLRVLNILELLAKEKLTLSTIAKKLNIPAGTLWPILQTLQEKKYIKCDLKNKSYYL
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCEEEEEECCCEEEE
DFKIIELGCNIKNENNIFEIIKKHMKNIRNLTNQTCQMGILKDGNVLYLEKIDANNTVQL
EEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEECCCEEEEEEECCCCEEEE
KSFIGTSYPAYATSLGKALLSNKNKKELEKLYPNNFDKITENTLNNINELYQQIKQIKKE
HHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KIAIEIGEMNPQIECMAIGIEHKNKIIAAISISYLIYCSNKTFREKNKKILLEEKNKIEK
HEEEEECCCCCCEEEEEEEECCCCCEEEEEEEEEEEEECCCHHHHCCCEEEEHHHHHHHH
VLKIYFNDLDTLY
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]