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The map label for this gene is lepB-1 [H]

Identifier: 153934577

GI number: 153934577

Start: 646211

End: 646819

Strand: Direct

Name: lepB-1 [H]

Synonym: CLC_0630

Alternate gene names: 153934577

Gene position: 646211-646819 (Clockwise)

Preceding gene: 258676992

Following gene: 153937226

Centisome position: 17.18

GC content: 27.59

Gene sequence:

>609_bases
TTGGATAAAAAGAAGATTATAAAAGAGATTAAAGGTTGGATTTTTTCTATTTTAGGAGCTATTCTTATTGCAGGTTTAGT
TAATAGTAAGGTTTTTGCAAAGGTTAGAGTACAGCAAAGCTCTATGGAGAATACTTTACTTACTAATGAACAATTAGTAG
TAGATAAATTAAGCTATAACTTTGTAGAACCTAAAAAAGGAGATATAATTATTTTTCATGAAAATAAAGAAAAGGGAACT
ATAGCTGAGGATACTTTAGAAATGGTAGATAATATAATATCCATATTTAATAATAACAATAATTCTATAGAAAAAGATGA
TAGATTAATTAAAAGAGTAATTGGTATTCCAGGGGATGAAATTCATATTAAAGATGGACATTTATATTTAAATGGTAAAA
GACTTGAAGAACCCTATGTAAAAGGGGAGACTATTGAAAGAGAATTTAAACTTCCTATTCAGATTCCAGAAAACAAATTG
TTTGTTTTAGGTGATAACAGAATGATAAGTAAGGATAGTAGGATGTTTGGGCTTATTGATTATAAGCAAGTTGAAGGTAA
GGCAATATACAGGGTATATCCTTTCGATCACATAGGAAATATAAAGTAA

Upstream 100 bases:

>100_bases
GATTAGCTATTTTTATTATGATAAGAGAAATTAATTAATGTTTAAATTAATTACTATCATAACAATGTGATTTAATTTTT
GAATTGGAGGGGGATTTATT

Downstream 100 bases:

>100_bases
AATTGATATAAATATTGTGTTTAGGTAACGCAATTTTATTAGATTTTATTATTATAATAATTTAAAAACTAAATTAAAAT
TATAAAAAATTAAAGTGGTA

Product: signal peptidase I

Products: NA

Alternate protein names: SPase IB; Leader peptidase IB [H]

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MDKKKIIKEIKGWIFSILGAILIAGLVNSKVFAKVRVQQSSMENTLLTNEQLVVDKLSYNFVEPKKGDIIIFHENKEKGT
IAEDTLEMVDNIISIFNNNNNSIEKDDRLIKRVIGIPGDEIHIKDGHLYLNGKRLEEPYVKGETIEREFKLPIQIPENKL
FVLGDNRMISKDSRMFGLIDYKQVEGKAIYRVYPFDHIGNIK

Sequences:

>Translated_202_residues
MDKKKIIKEIKGWIFSILGAILIAGLVNSKVFAKVRVQQSSMENTLLTNEQLVVDKLSYNFVEPKKGDIIIFHENKEKGT
IAEDTLEMVDNIISIFNNNNNSIEKDDRLIKRVIGIPGDEIHIKDGHLYLNGKRLEEPYVKGETIEREFKLPIQIPENKL
FVLGDNRMISKDSRMFGLIDYKQVEGKAIYRVYPFDHIGNIK
>Mature_202_residues
MDKKKIIKEIKGWIFSILGAILIAGLVNSKVFAKVRVQQSSMENTLLTNEQLVVDKLSYNFVEPKKGDIIIFHENKEKGT
IAEDTLEMVDNIISIFNNNNNSIEKDDRLIKRVIGIPGDEIHIKDGHLYLNGKRLEEPYVKGETIEREFKLPIQIPENKL
FVLGDNRMISKDSRMFGLIDYKQVEGKAIYRVYPFDHIGNIK

Specific function: Essential for cell viability [H]

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 23247; Mature: 23247

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKKKIIKEIKGWIFSILGAILIAGLVNSKVFAKVRVQQSSMENTLLTNEQLVVDKLSYN
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHCCCHHHCCCCEEEEEECCCC
FVEPKKGDIIIFHENKEKGTIAEDTLEMVDNIISIFNNNNNSIEKDDRLIKRVIGIPGDE
CCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCE
IHIKDGHLYLNGKRLEEPYVKGETIEREFKLPIQIPENKLFVLGDNRMISKDSRMFGLID
EEEECCEEEECCCCCCCCCCCCCCCCEEEECCEEECCCEEEEEECCEEECCCCCEEEEEE
YKQVEGKAIYRVYPFDHIGNIK
EEECCCEEEEEEECCHHCCCCC
>Mature Secondary Structure
MDKKKIIKEIKGWIFSILGAILIAGLVNSKVFAKVRVQQSSMENTLLTNEQLVVDKLSYN
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHCCCHHHCCCCEEEEEECCCC
FVEPKKGDIIIFHENKEKGTIAEDTLEMVDNIISIFNNNNNSIEKDDRLIKRVIGIPGDE
CCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCE
IHIKDGHLYLNGKRLEEPYVKGETIEREFKLPIQIPENKLFVLGDNRMISKDSRMFGLID
EEEECCEEEECCCCCCCCCCCCCCCCEEEECCEEECCCEEEEEECCEEECCCCCEEEEEE
YKQVEGKAIYRVYPFDHIGNIK
EEECCCEEEEEEECCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA