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The map label for this gene is metA

Identifier: 152977586

GI number: 152977586

Start: 3977340

End: 3978245

Strand: Reverse

Name: metA

Synonym: Bcer98_3924

Alternate gene names: 152977586

Gene position: 3978245-3977340 (Counterclockwise)

Preceding gene: 152977587

Following gene: 152977585

Centisome position: 97.34

GC content: 35.21

Gene sequence:

>906_bases
ATGCCAATCATAATTGACAAGGATTTACCAGCTCGTAAAGTGTTGCAAGAAGAAAATATTTTTACCATGACAAAGGAGCG
AGCAGAAAAACAAGATATTAGAGCTTTAAAAATTGCAATTTTGAACTTAATGCCCAAAAAGCAAGAAACCGAGGCACAAT
TACTTAGATTACTCGGTAATACGCCCCTCCAATTGGATATGCATTTACTTCATATGGAGTCGCATATTTCTCGCAATGTA
GCGCAAGATCATTTAACAAGTTTTTATAAAACATTTCGCGATATTGAAAAAGAGAGATTTGATGGGCTTATTATTACAGG
AGCTCCGATTGAAACTCTTCCATTTGAAGATGTGGATTATTGGGAAGAACTCAAGAAAATCATGGATTATTCGAAAACGA
ATGTAACGTCTACATTGCATATTTGTTGGGGAGCACAAGCTGGATTGTACTATCATTATGGGATTCCTAAATATCCGCTT
GCAGAAAAAATGTTCGGTGTGTTCGAACATGAAGTACTTGAGCAACATGTGAAATTATTACAAGGATTTGATGAGCTCTT
TTTTGCACCGCATTCTCGTCATACAGAAGTACATGCAGCAGACATAGAAAAGGTAGAAGACTTGAAATTGCTTGCGATTT
CAGAAGAAGCGGGTGTTTATCTTGTTATCGGACAAAATGGAAAACATATTTTTGTTCTTGGGCATAGCGAATATAGCTGT
GATACATTAAAACGAGAATATGAACGGGATATACAAAGAGGATTGAATATAGCAGTTCCAAAAAACTATTTCAAGTATAA
TAATCCAGATGAAAAACCACTTGTTAGATGGCGAAGTCATGGCAATTTACTATTTTCGAATTGGCTTAATTATTATGTGT
ATCAGGAAACCCCTTATATTTTGTAA

Upstream 100 bases:

>100_bases
GCCGGTGTTACGTCAGATTTAATTCGTTTATCAGTTGGTATAGAAGATGTTTCTGATATTATTGCTGATTTGGAAGCAGC
TTTAATTGGAGGCAAAACAA

Downstream 100 bases:

>100_bases
AGGATGCTATAACATGTGGTGGCGTTTTCTTTACGTAGACCAATTTTTATTTTTTGAATGTTCTAAATACATTGTTTTTC
GGAATTTTAAACTATATAAT

Product: homoserine O-succinyltransferase

Products: NA

Alternate protein names: Homoserine O-transsuccinylase; HTS

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MPIIIDKDLPARKVLQEENIFTMTKERAEKQDIRALKIAILNLMPKKQETEAQLLRLLGNTPLQLDMHLLHMESHISRNV
AQDHLTSFYKTFRDIEKERFDGLIITGAPIETLPFEDVDYWEELKKIMDYSKTNVTSTLHICWGAQAGLYYHYGIPKYPL
AEKMFGVFEHEVLEQHVKLLQGFDELFFAPHSRHTEVHAADIEKVEDLKLLAISEEAGVYLVIGQNGKHIFVLGHSEYSC
DTLKREYERDIQRGLNIAVPKNYFKYNNPDEKPLVRWRSHGNLLFSNWLNYYVYQETPYIL

Sequences:

>Translated_301_residues
MPIIIDKDLPARKVLQEENIFTMTKERAEKQDIRALKIAILNLMPKKQETEAQLLRLLGNTPLQLDMHLLHMESHISRNV
AQDHLTSFYKTFRDIEKERFDGLIITGAPIETLPFEDVDYWEELKKIMDYSKTNVTSTLHICWGAQAGLYYHYGIPKYPL
AEKMFGVFEHEVLEQHVKLLQGFDELFFAPHSRHTEVHAADIEKVEDLKLLAISEEAGVYLVIGQNGKHIFVLGHSEYSC
DTLKREYERDIQRGLNIAVPKNYFKYNNPDEKPLVRWRSHGNLLFSNWLNYYVYQETPYIL
>Mature_300_residues
PIIIDKDLPARKVLQEENIFTMTKERAEKQDIRALKIAILNLMPKKQETEAQLLRLLGNTPLQLDMHLLHMESHISRNVA
QDHLTSFYKTFRDIEKERFDGLIITGAPIETLPFEDVDYWEELKKIMDYSKTNVTSTLHICWGAQAGLYYHYGIPKYPLA
EKMFGVFEHEVLEQHVKLLQGFDELFFAPHSRHTEVHAADIEKVEDLKLLAISEEAGVYLVIGQNGKHIFVLGHSEYSCD
TLKREYERDIQRGLNIAVPKNYFKYNNPDEKPLVRWRSHGNLLFSNWLNYYVYQETPYIL

Specific function: Methionine biosynthesis; HTS variant; first step. [C]

COG id: COG1897

COG function: function code E; Homoserine trans-succinylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HTS family

Homologues:

Organism=Escherichia coli, GI1790443, Length=301, Percent_Identity=52.4916943521595, Blast_Score=333, Evalue=7e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): META_BACCN (A7GVF0)

Other databases:

- EMBL:   CP000764
- RefSeq:   YP_001377103.1
- ProteinModelPortal:   A7GVF0
- SMR:   A7GVF0
- STRING:   A7GVF0
- EnsemblBacteria:   EBBACT00000038207
- GeneID:   5344200
- GenomeReviews:   CP000764_GR
- KEGG:   bcy:Bcer98_3924
- eggNOG:   COG1897
- GeneTree:   EBGT00050000001387
- HOGENOM:   HBG362506
- OMA:   QAGLYYH
- ProtClustDB:   PRK05368
- BioCyc:   BCER315749:BCER98_3924-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00295
- InterPro:   IPR005697
- PANTHER:   PTHR20919
- PIRSF:   PIRSF000450
- ProDom:   PD037892
- TIGRFAMs:   TIGR01001

Pfam domain/function: PF04204 HTS

EC number: =2.3.1.46

Molecular weight: Translated: 35282; Mature: 35151

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: ACT_SITE 142-142

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIIIDKDLPARKVLQEENIFTMTKERAEKQDIRALKIAILNLMPKKQETEAQLLRLLGN
CCEEECCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
TPLQLDMHLLHMESHISRNVAQDHLTSFYKTFRDIEKERFDGLIITGAPIETLPFEDVDY
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCHH
WEELKKIMDYSKTNVTSTLHICWGAQAGLYYHYGIPKYPLAEKMFGVFEHEVLEQHVKLL
HHHHHHHHCCCCCCCCEEEEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
QGFDELFFAPHSRHTEVHAADIEKVEDLKLLAISEEAGVYLVIGQNGKHIFVLGHSEYSC
HHHHHHHCCCCCCCCEEEHHHHHHHCCEEEEEEECCCCEEEEECCCCCEEEEEECCCCCH
DTLKREYERDIQRGLNIAVPKNYFKYNNPDEKPLVRWRSHGNLLFSNWLNYYVYQETPYI
HHHHHHHHHHHHCCCEEECCCHHCCCCCCCCCHHHHHHCCCCEEEECHHCEEEEECCCCC
L
C
>Mature Secondary Structure 
PIIIDKDLPARKVLQEENIFTMTKERAEKQDIRALKIAILNLMPKKQETEAQLLRLLGN
CEEECCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
TPLQLDMHLLHMESHISRNVAQDHLTSFYKTFRDIEKERFDGLIITGAPIETLPFEDVDY
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCHH
WEELKKIMDYSKTNVTSTLHICWGAQAGLYYHYGIPKYPLAEKMFGVFEHEVLEQHVKLL
HHHHHHHHCCCCCCCCEEEEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
QGFDELFFAPHSRHTEVHAADIEKVEDLKLLAISEEAGVYLVIGQNGKHIFVLGHSEYSC
HHHHHHHCCCCCCCCEEEHHHHHHHCCEEEEEEECCCCEEEEECCCCCEEEEEECCCCCH
DTLKREYERDIQRGLNIAVPKNYFKYNNPDEKPLVRWRSHGNLLFSNWLNYYVYQETPYI
HHHHHHHHHHHHCCCEEECCCHHCCCCCCCCCHHHHHHCCCCEEEECHHCEEEEECCCCC
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA