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The map label for this gene is ezrA

Identifier: 152977016

GI number: 152977016

Start: 3391391

End: 3393100

Strand: Reverse

Name: ezrA

Synonym: Bcer98_3321

Alternate gene names: 152977016

Gene position: 3393100-3391391 (Counterclockwise)

Preceding gene: 152977017

Following gene: 152977015

Centisome position: 83.02

GC content: 36.43

Gene sequence:

>1710_bases
ATGGATTCTATCTTAACGATCGTTATCATTGTGGTAAGCTCTATTCTAGTGCTACTCATGATAGAGCTCATGATAAGAAA
TCGTTCATATAAAGATATCGAAGCACTGGAACAGTGGCAACAAGAAATAAAAGATAAACCGGTTGCAGATGAATTGAAAC
GGGTAAAAGATTTAAATATGACAGGGCAAACAGAAGAGTTGTTTGGAAAGTGGCGTGAAGACTGGGATGAAATCGTAGCA
ACAATTCTTCCAAAAGCCGAAAAAGATTTAGAAGGCGCACGGAAATATGCCTCGCAATTTTCCTTCCGAAAAGCAAAGTA
TGCGATGAATGAAGCTATTAGCAACTTAGATGAAGCGGATAATCGTATCACGGATATTTTAAACGAATTACAGCAATTAT
TAGAGAGTCATGAGAAAAATAGTGCGGAAATTGATGGATTACGCGATGTATATCGTAATATGAAGAAGAGTGTACTTGCG
CACCGTCACATGTATGGCGCGGCAGAGCAGAAGATTGAAGAGTTGTTAGATGTCGAATCTGACAAATTTCAAAAATTTGA
GGAAGCAACAGCGAATGGTGATTATTTAAAAGCAAGAGACATTGTAATGAGTTTAGAAGAAGGGTTATCAAACTTGGAAG
GCATGATCCAGGAAGTTCCTGACTTATTAGTAGAGTGTCAGGCTACATTACCAGTACAATTAGAAGATTTATTACAAGGC
CATGACGAAATGAAAAAGCAAGGCTATGTCTTAAATCATTTGGAAATCCCTAAAGAAGTACGTGATATGACGAAACAACT
ACAAACATGTCTAATAGATATACAAGAGCTTCATATTACAGAAGCAGCAGAGAAAATTGAAGCTTTAAAGACGCGTTTAG
ACACGTTATATGATCAATTAGAAAAAGAAGTGCATGCGAAATATTATGTGGAGCAAAAAACGATACGTGTTTACGATGAC
TTAGAAGAGATTCATGAACAAGCGCTTGAAACAAAAGCAGAAACACAGTTTGTGAAACAAAGCTATCAGTTACAAGATAA
AGATATTGAATCGCAAAAGATCATTGAAAAGCAAATGCACATTTTGATGAAACGCTTTGAAGTATTGCAATTACGTGTTG
CAGAGCAAGATATTGCATTTTCTGTTATTCGTGAAGAACTTGAAGAGATTTATGAGCAATGTGAAACGTTAAAAGTCCTT
CATGCAGAATATAAAGAGATGCTACAGGCAATGCGTAAGGAAGAATTTGAAGCACGTGAGAAATTACAAGAGATGCGCAA
TATGATTTTAGAGACAAAACGTCTTATGCAAAAGTCTAACTTGCCAGGTCTTCCAGAGAGTATTATGGAAGAGTTACAAA
AGGGGCAAGAAGCAATGCAGGCTGTATATGGACACTTAGAATTAAAACCACTGAATATGCATGTAGTAAATAGCGAGTTA
GAGGAAGCATATGCGATTGTAAATGATGTATCTGAACGAACACAAGATGTGATTGGTCAAGCATATTTAGTAGAAAAATT
AATTCAATATGGTAATCGCTATCGTAGCCAAGATATGGATTTAGCCTATAGTTTAGACAACGCGGAGAGATTATTCCGTG
AATATGAATATGATGCGGCTTTAGAACAAGCAGCTTCCGTTTTAGAACAACTGGAACCTGGTGTTGTTCAAAAAATTGCT
GAGTTTGTAGATAATGAACAAACCTCTTGA

Upstream 100 bases:

>100_bases
TAGTTGTTAAATATAGGGGATTTCCCTTTTTATACATAATGCCTTCCATTTCATAAACGGAACGGACAAAAATAGAGATA
CAATTAGGAGGCTTTTTTGC

Downstream 100 bases:

>100_bases
TGAAAAGAGGTTTGTTTTTTTATGTCTCAATGTGTAAATTAACAGATGATGTTGTTATAATGAATAGCGGAATAACACAA
AGCTTTTCGTTTCAAGATAC

Product: septation ring formation regulator EzrA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 569; Mature: 569

Protein sequence:

>569_residues
MDSILTIVIIVVSSILVLLMIELMIRNRSYKDIEALEQWQQEIKDKPVADELKRVKDLNMTGQTEELFGKWREDWDEIVA
TILPKAEKDLEGARKYASQFSFRKAKYAMNEAISNLDEADNRITDILNELQQLLESHEKNSAEIDGLRDVYRNMKKSVLA
HRHMYGAAEQKIEELLDVESDKFQKFEEATANGDYLKARDIVMSLEEGLSNLEGMIQEVPDLLVECQATLPVQLEDLLQG
HDEMKKQGYVLNHLEIPKEVRDMTKQLQTCLIDIQELHITEAAEKIEALKTRLDTLYDQLEKEVHAKYYVEQKTIRVYDD
LEEIHEQALETKAETQFVKQSYQLQDKDIESQKIIEKQMHILMKRFEVLQLRVAEQDIAFSVIREELEEIYEQCETLKVL
HAEYKEMLQAMRKEEFEAREKLQEMRNMILETKRLMQKSNLPGLPESIMEELQKGQEAMQAVYGHLELKPLNMHVVNSEL
EEAYAIVNDVSERTQDVIGQAYLVEKLIQYGNRYRSQDMDLAYSLDNAERLFREYEYDAALEQAASVLEQLEPGVVQKIA
EFVDNEQTS

Sequences:

>Translated_569_residues
MDSILTIVIIVVSSILVLLMIELMIRNRSYKDIEALEQWQQEIKDKPVADELKRVKDLNMTGQTEELFGKWREDWDEIVA
TILPKAEKDLEGARKYASQFSFRKAKYAMNEAISNLDEADNRITDILNELQQLLESHEKNSAEIDGLRDVYRNMKKSVLA
HRHMYGAAEQKIEELLDVESDKFQKFEEATANGDYLKARDIVMSLEEGLSNLEGMIQEVPDLLVECQATLPVQLEDLLQG
HDEMKKQGYVLNHLEIPKEVRDMTKQLQTCLIDIQELHITEAAEKIEALKTRLDTLYDQLEKEVHAKYYVEQKTIRVYDD
LEEIHEQALETKAETQFVKQSYQLQDKDIESQKIIEKQMHILMKRFEVLQLRVAEQDIAFSVIREELEEIYEQCETLKVL
HAEYKEMLQAMRKEEFEAREKLQEMRNMILETKRLMQKSNLPGLPESIMEELQKGQEAMQAVYGHLELKPLNMHVVNSEL
EEAYAIVNDVSERTQDVIGQAYLVEKLIQYGNRYRSQDMDLAYSLDNAERLFREYEYDAALEQAASVLEQLEPGVVQKIA
EFVDNEQTS
>Mature_569_residues
MDSILTIVIIVVSSILVLLMIELMIRNRSYKDIEALEQWQQEIKDKPVADELKRVKDLNMTGQTEELFGKWREDWDEIVA
TILPKAEKDLEGARKYASQFSFRKAKYAMNEAISNLDEADNRITDILNELQQLLESHEKNSAEIDGLRDVYRNMKKSVLA
HRHMYGAAEQKIEELLDVESDKFQKFEEATANGDYLKARDIVMSLEEGLSNLEGMIQEVPDLLVECQATLPVQLEDLLQG
HDEMKKQGYVLNHLEIPKEVRDMTKQLQTCLIDIQELHITEAAEKIEALKTRLDTLYDQLEKEVHAKYYVEQKTIRVYDD
LEEIHEQALETKAETQFVKQSYQLQDKDIESQKIIEKQMHILMKRFEVLQLRVAEQDIAFSVIREELEEIYEQCETLKVL
HAEYKEMLQAMRKEEFEAREKLQEMRNMILETKRLMQKSNLPGLPESIMEELQKGQEAMQAVYGHLELKPLNMHVVNSEL
EEAYAIVNDVSERTQDVIGQAYLVEKLIQYGNRYRSQDMDLAYSLDNAERLFREYEYDAALEQAASVLEQLEPGVVQKIA
EFVDNEQTS

Specific function: Negative regulator of ftsZ ring formation; modulates the frequency and position of ftsZ ring formation. Inhibits ftsZ ring formation at polar sites. Interacts either with ftsZ or with one of its binding partners to promote depolymerization

COG id: COG4477

COG function: function code D; Negative regulator of septation ring formation

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein. Note=Colocalized with ftsZ to the nascent septal site (By similarity)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ezrA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): EZRA_BACCN (A7GTT0)

Other databases:

- EMBL:   CP000764
- RefSeq:   YP_001376533.1
- STRING:   A7GTT0
- EnsemblBacteria:   EBBACT00000039452
- GeneID:   5347076
- GenomeReviews:   CP000764_GR
- KEGG:   bcy:Bcer98_3321
- eggNOG:   COG4477
- GeneTree:   EBGT00050000000289
- HOGENOM:   HBG345654
- OMA:   MDIQELH
- ProtClustDB:   PRK04778
- BioCyc:   BCER315749:BCER98_3321-MONOMER
- HAMAP:   MF_00728
- InterPro:   IPR010379

Pfam domain/function: PF06160 EzrA

EC number: NA

Molecular weight: Translated: 66414; Mature: 66414

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x22d063e8)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSILTIVIIVVSSILVLLMIELMIRNRSYKDIEALEQWQQEIKDKPVADELKRVKDLNM
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
TGQTEELFGKWREDWDEIVATILPKAEKDLEGARKYASQFSFRKAKYAMNEAISNLDEAD
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NRITDILNELQQLLESHEKNSAEIDGLRDVYRNMKKSVLAHRHMYGAAEQKIEELLDVES
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
DKFQKFEEATANGDYLKARDIVMSLEEGLSNLEGMIQEVPDLLVECQATLPVQLEDLLQG
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCC
HDEMKKQGYVLNHLEIPKEVRDMTKQLQTCLIDIQELHITEAAEKIEALKTRLDTLYDQL
HHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKEVHAKYYVEQKTIRVYDDLEEIHEQALETKAETQFVKQSYQLQDKDIESQKIIEKQMH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
ILMKRFEVLQLRVAEQDIAFSVIREELEEIYEQCETLKVLHAEYKEMLQAMRKEEFEARE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLQEMRNMILETKRLMQKSNLPGLPESIMEELQKGQEAMQAVYGHLELKPLNMHVVNSEL
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECHHHHHHHHH
EEAYAIVNDVSERTQDVIGQAYLVEKLIQYGNRYRSQDMDLAYSLDNAERLFREYEYDAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHHHH
LEQAASVLEQLEPGVVQKIAEFVDNEQTS
HHHHHHHHHHHCCHHHHHHHHHHCCCCCH
>Mature Secondary Structure
MDSILTIVIIVVSSILVLLMIELMIRNRSYKDIEALEQWQQEIKDKPVADELKRVKDLNM
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
TGQTEELFGKWREDWDEIVATILPKAEKDLEGARKYASQFSFRKAKYAMNEAISNLDEAD
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NRITDILNELQQLLESHEKNSAEIDGLRDVYRNMKKSVLAHRHMYGAAEQKIEELLDVES
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
DKFQKFEEATANGDYLKARDIVMSLEEGLSNLEGMIQEVPDLLVECQATLPVQLEDLLQG
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCC
HDEMKKQGYVLNHLEIPKEVRDMTKQLQTCLIDIQELHITEAAEKIEALKTRLDTLYDQL
HHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKEVHAKYYVEQKTIRVYDDLEEIHEQALETKAETQFVKQSYQLQDKDIESQKIIEKQMH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
ILMKRFEVLQLRVAEQDIAFSVIREELEEIYEQCETLKVLHAEYKEMLQAMRKEEFEARE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLQEMRNMILETKRLMQKSNLPGLPESIMEELQKGQEAMQAVYGHLELKPLNMHVVNSEL
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECHHHHHHHHH
EEAYAIVNDVSERTQDVIGQAYLVEKLIQYGNRYRSQDMDLAYSLDNAERLFREYEYDAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHHHH
LEQAASVLEQLEPGVVQKIAEFVDNEQTS
HHHHHHHHHHHCCHHHHHHHHHHCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA