Click here to switch to the map view.

The map label for this gene is gltC [H]

Identifier: 152977017

GI number: 152977017

Start: 3393318

End: 3394157

Strand: Reverse

Name: gltC [H]

Synonym: Bcer98_3322

Alternate gene names: 152977017

Gene position: 3394157-3393318 (Counterclockwise)

Preceding gene: 152977019

Following gene: 152977016

Centisome position: 83.05

GC content: 36.9

Gene sequence:

>840_bases
ATGGATTTTGAAGCGATACGATCGCTAATTGAGGTCAAACAGCAAAAGAGTTTATCGAAAGCGAGTAAACTGCTGCATAT
TTCGCAACCGGCGCTGAGTAAGCAAATTCAGAGGTTAGAAGCAGACCTTGAGGTGACAATATTAAAGCGATCTGCTCAAG
GAGTTGAATTAACAGAAGCTGGGGAATTATTTTTAAGCCGGATGGAACCCATTTTAAAACAAATCAATGAAGTGAAGATG
GAACTAAGGGGATATCAAGTAAAGAAAAAAATTTCTCTTGGTATATTGCCGAGTTTAGCAGCTCATTATATATCGAGATA
TAAAGGAATATTGGAAAAAACATACGAAGTAGAATGGTATATTGAGCATACAAAAATATTAATGGAATTATTTAAAGCGC
GGAAGATAGATGCGATGTTAATTGATTCTTCCGTAGATGATGCAAAGTATATAAGAAAAGTACGCCAAGAACATATCGTT
TGTGTTGTTTCAAGTGAGCATATATATAAAGGTAAAAAAATTATAAAAGTGAGCGACTTGCAGCATGAAAAACTCATTAT
TTATCCAGAGATTTGTGATGTGAGAAAAATGATTATGACAGTATTTCAGGGAGTGGGAGTCAAGCCGACAATCGCTGTTG
AAACACCGTATGCGGAGCCGATGTTGGCGATGGTACGAGCGGGAGTAGGAATTACACTACTGCCAGAAATCGCAGTAAAA
CAAGGGGGGAAAGAAGGTATTTGTATGATTCCTATAGAGCCAGCATTAACGAGATGCATTTATTTTGTATCTCATAGGGA
AGAGGAAACGTTTGTACAAATATTTGGAGAGATAGATTAA

Upstream 100 bases:

>100_bases
CATCAAATGAAGCATGAAGAGAGTATAGCGCTTGTTTAATAGATAGAGGAAATACCGTTTTTTTATAACGGCTATAATTT
TTAGTTAGAGGTGTATGGTT

Downstream 100 bases:

>100_bases
AATTGGATATTTATGTAAAAGAGATATAGAAATATGCCCCTTATAACAAAAGAAACATGAAATTTTAAAAAAACTAGGTC
AAAAACAAGGCATAACATGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MDFEAIRSLIEVKQQKSLSKASKLLHISQPALSKQIQRLEADLEVTILKRSAQGVELTEAGELFLSRMEPILKQINEVKM
ELRGYQVKKKISLGILPSLAAHYISRYKGILEKTYEVEWYIEHTKILMELFKARKIDAMLIDSSVDDAKYIRKVRQEHIV
CVVSSEHIYKGKKIIKVSDLQHEKLIIYPEICDVRKMIMTVFQGVGVKPTIAVETPYAEPMLAMVRAGVGITLLPEIAVK
QGGKEGICMIPIEPALTRCIYFVSHREEETFVQIFGEID

Sequences:

>Translated_279_residues
MDFEAIRSLIEVKQQKSLSKASKLLHISQPALSKQIQRLEADLEVTILKRSAQGVELTEAGELFLSRMEPILKQINEVKM
ELRGYQVKKKISLGILPSLAAHYISRYKGILEKTYEVEWYIEHTKILMELFKARKIDAMLIDSSVDDAKYIRKVRQEHIV
CVVSSEHIYKGKKIIKVSDLQHEKLIIYPEICDVRKMIMTVFQGVGVKPTIAVETPYAEPMLAMVRAGVGITLLPEIAVK
QGGKEGICMIPIEPALTRCIYFVSHREEETFVQIFGEID
>Mature_279_residues
MDFEAIRSLIEVKQQKSLSKASKLLHISQPALSKQIQRLEADLEVTILKRSAQGVELTEAGELFLSRMEPILKQINEVKM
ELRGYQVKKKISLGILPSLAAHYISRYKGILEKTYEVEWYIEHTKILMELFKARKIDAMLIDSSVDDAKYIRKVRQEHIV
CVVSSEHIYKGKKIIKVSDLQHEKLIIYPEICDVRKMIMTVFQGVGVKPTIAVETPYAEPMLAMVRAGVGITLLPEIAVK
QGGKEGICMIPIEPALTRCIYFVSHREEETFVQIFGEID

Specific function: Positive regulator of glutamate biosynthesis (gltAB genes). Negatively regulates its own expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=271, Percent_Identity=24.3542435424354, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI157672245, Length=268, Percent_Identity=24.6268656716418, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI145693105, Length=277, Percent_Identity=22.7436823104693, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI2367136, Length=279, Percent_Identity=22.2222222222222, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788297, Length=107, Percent_Identity=31.7757009345794, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1789204, Length=282, Percent_Identity=25.531914893617, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1787601, Length=108, Percent_Identity=38.8888888888889, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788887, Length=99, Percent_Identity=36.3636363636364, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788748, Length=268, Percent_Identity=22.3880597014925, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31800; Mature: 31800

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFEAIRSLIEVKQQKSLSKASKLLHISQPALSKQIQRLEADLEVTILKRSAQGVELTEA
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEECCCCCCEEHHH
GELFLSRMEPILKQINEVKMELRGYQVKKKISLGILPSLAAHYISRYKGILEKTYEVEWY
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEEE
IEHTKILMELFKARKIDAMLIDSSVDDAKYIRKVRQEHIVCVVSSEHIYKGKKIIKVSDL
EHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHEEEEEECCCHHCCCEEEEEECC
QHEKLIIYPEICDVRKMIMTVFQGVGVKPTIAVETPYAEPMLAMVRAGVGITLLPEIAVK
CCCEEEEEHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHCCCCEEECHHHHHH
QGGKEGICMIPIEPALTRCIYFVSHREEETFVQIFGEID
CCCCCCEEEEECCHHHHHHHHHHHCCCHHHHHHHHCCCC
>Mature Secondary Structure
MDFEAIRSLIEVKQQKSLSKASKLLHISQPALSKQIQRLEADLEVTILKRSAQGVELTEA
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEECCCCCCEEHHH
GELFLSRMEPILKQINEVKMELRGYQVKKKISLGILPSLAAHYISRYKGILEKTYEVEWY
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEEE
IEHTKILMELFKARKIDAMLIDSSVDDAKYIRKVRQEHIVCVVSSEHIYKGKKIIKVSDL
EHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHEEEEEECCCHHCCCEEEEEECC
QHEKLIIYPEICDVRKMIMTVFQGVGVKPTIAVETPYAEPMLAMVRAGVGITLLPEIAVK
CCCEEEEEHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHCCCCEEECHHHHHH
QGGKEGICMIPIEPALTRCIYFVSHREEETFVQIFGEID
CCCCCCEEEEECCHHHHHHHHHHHCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2548995; 9384377 [H]