Click here to switch to the map view.

The map label for this gene is bioC [H]

Identifier: 152976525

GI number: 152976525

Start: 2889442

End: 2890299

Strand: Reverse

Name: bioC [H]

Synonym: Bcer98_2814

Alternate gene names: 152976525

Gene position: 2890299-2889442 (Counterclockwise)

Preceding gene: 152976526

Following gene: 152976524

Centisome position: 70.72

GC content: 36.6

Gene sequence:

>858_bases
ATGATCAATAAAACATTGTTGCAAAAACGATTTAATAGAGCGGCTGTATCCTATGATCAATATGCCAATGTACAAAAGAA
AATGGCTCGTCATTTACTTTCGCAGTTGGAAAAACGATATAGCAAAGCAGCGGCGATTCGAATTTTAGAACTTGGCTGCG
GAACGGGATATATCACGGAGAAGCTTGTGCATTTATTTCCGAATGCACAGATTACAGCTATTGACTTCGCGGAGAGTATG
ATTGCTGTTGCGAAACAAAGACGCCATGTTGATGAAGTTACCTTTCGATGTGAAGATATTGAAAAGCTTATATTAGACGA
CTTCTATGATGTCATCATCTCCAATGCAACATTTCAATGGTTAAATGATTTGCAGGTGTCCCTTGTAAAGTTATATAAGC
ATTTAGCTGGAGAAGGCATCTTGTTATTTTCAACATTTGGAAATCGAACGTTCCAAGAACTCCATCGTGCTTTTGAACGA
GCGAAAGAAGAAAAAAATATAAAAAGTCATGTATCAATTGGACAGCGTCTTTTTACAAAAGCGCAGTTGCAAAATATATG
TTCCATAAAAAAAGGGAATGTTCATGTATCTGAAACATGTTACATAGAGAAATTTACTCATGTTAGAGACTTTTTTAAGT
CGATTCGCAAAGTTGGTGCAACAAATAGTAATGAAGATACGTATTGTCAAAGTCCTTCTCTCTTTCGGGCGATGCTTCGC
ATATATGAGAGAGACTTTACGAAAGAAGGGGAGATTATAGCAACGTACCATGCTTTATTTGCGCACATAGAAAAAGAGGG
GAAGAGGAGAAATGAAACAAATACAAACAAAAGTAGATTGGAAGAAAATTGCGTTTGA

Upstream 100 bases:

>100_bases
GCAACACTTAAAGTGATTCATCAAGCGGGGCATGCCATTTGTATAACGAATTTTGAATATTGCGCAAATGAAATTAATAA
ATTCATAGAGGGGATACGAA

Downstream 100 bases:

>100_bases
AGGGATAGAAGGAAAAAGGATAACGAAAGAGGATGCGTTAGCGATTTTAGAAGCAGATGATACAGAAGTATTAGAGATTA
TGAATGCTGCATATATGATT

Product: biotin biosynthesis protein BioC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MINKTLLQKRFNRAAVSYDQYANVQKKMARHLLSQLEKRYSKAAAIRILELGCGTGYITEKLVHLFPNAQITAIDFAESM
IAVAKQRRHVDEVTFRCEDIEKLILDDFYDVIISNATFQWLNDLQVSLVKLYKHLAGEGILLFSTFGNRTFQELHRAFER
AKEEKNIKSHVSIGQRLFTKAQLQNICSIKKGNVHVSETCYIEKFTHVRDFFKSIRKVGATNSNEDTYCQSPSLFRAMLR
IYERDFTKEGEIIATYHALFAHIEKEGKRRNETNTNKSRLEENCV

Sequences:

>Translated_285_residues
MINKTLLQKRFNRAAVSYDQYANVQKKMARHLLSQLEKRYSKAAAIRILELGCGTGYITEKLVHLFPNAQITAIDFAESM
IAVAKQRRHVDEVTFRCEDIEKLILDDFYDVIISNATFQWLNDLQVSLVKLYKHLAGEGILLFSTFGNRTFQELHRAFER
AKEEKNIKSHVSIGQRLFTKAQLQNICSIKKGNVHVSETCYIEKFTHVRDFFKSIRKVGATNSNEDTYCQSPSLFRAMLR
IYERDFTKEGEIIATYHALFAHIEKEGKRRNETNTNKSRLEENCV
>Mature_285_residues
MINKTLLQKRFNRAAVSYDQYANVQKKMARHLLSQLEKRYSKAAAIRILELGCGTGYITEKLVHLFPNAQITAIDFAESM
IAVAKQRRHVDEVTFRCEDIEKLILDDFYDVIISNATFQWLNDLQVSLVKLYKHLAGEGILLFSTFGNRTFQELHRAFER
AKEEKNIKSHVSIGQRLFTKAQLQNICSIKKGNVHVSETCYIEKFTHVRDFFKSIRKVGATNSNEDTYCQSPSLFRAMLR
IYERDFTKEGEIIATYHALFAHIEKEGKRRNETNTNKSRLEENCV

Specific function: BioC is involved in an early, but chemically unexplored, step in the conversion of pimelic acid to biotin [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

Organism=Escherichia coli, GI1786994, Length=269, Percent_Identity=25.6505576208178, Blast_Score=83, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011814
- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: NA

Molecular weight: Translated: 33083; Mature: 33083

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINKTLLQKRFNRAAVSYDQYANVQKKMARHLLSQLEKRYSKAAAIRILELGCGTGYITE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
KLVHLFPNAQITAIDFAESMIAVAKQRRHVDEVTFRCEDIEKLILDDFYDVIISNATFQW
HHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
LNDLQVSLVKLYKHLAGEGILLFSTFGNRTFQELHRAFERAKEEKNIKSHVSIGQRLFTK
HHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQLQNICSIKKGNVHVSETCYIEKFTHVRDFFKSIRKVGATNSNEDTYCQSPSLFRAMLR
HHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
IYERDFTKEGEIIATYHALFAHIEKEGKRRNETNTNKSRLEENCV
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCC
>Mature Secondary Structure
MINKTLLQKRFNRAAVSYDQYANVQKKMARHLLSQLEKRYSKAAAIRILELGCGTGYITE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
KLVHLFPNAQITAIDFAESMIAVAKQRRHVDEVTFRCEDIEKLILDDFYDVIISNATFQW
HHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
LNDLQVSLVKLYKHLAGEGILLFSTFGNRTFQELHRAFERAKEEKNIKSHVSIGQRLFTK
HHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQLQNICSIKKGNVHVSETCYIEKFTHVRDFFKSIRKVGATNSNEDTYCQSPSLFRAMLR
HHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
IYERDFTKEGEIIATYHALFAHIEKEGKRRNETNTNKSRLEENCV
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8250549 [H]