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The map label for this gene is malR [H]

Identifier: 152976423

GI number: 152976423

Start: 2795482

End: 2796510

Strand: Reverse

Name: malR [H]

Synonym: Bcer98_2711

Alternate gene names: 152976423

Gene position: 2796510-2795482 (Counterclockwise)

Preceding gene: 152976424

Following gene: 152976420

Centisome position: 68.42

GC content: 37.8

Gene sequence:

>1029_bases
ATGACAGTTACGATTAAAGACGTAGCGAAAAAAGCGAATGTTGCGCCATCAACGGTGTCTCGTGTGATTGCTGATAATCC
AAGTATAAGTGAAAAGACGAAGCGGCGAGTTCGTAAAGTCATGAGCGAGCTCGGATATCATCCGAATTTAAATGCAAGAA
GCCTTGCCAATCAAACGACGAAAACGATTGGTCTTGTTATGCCAAGTTCTGCAAATAAAGCATTTCAAAACCCGTTTTTT
CCAGAAGTTATTCGTGGGATTAGTTCGTTTGCTCATGTTGAAGGGTATGCTTTATATATGTCAACGGGGGAGACGGAAGA
AGAGATTTTTAACGGGGTCATCAAAATGGTGCAAGGACGTCAAATCGGAGGCATTATCTTACTGTATTCACGTGAAAATG
ACCGGATTATTCAATATTTAAATGAGAAAAATTTCCCGTTTGTTTTAATTGGAAAACCATATGACAAAAAAGACAAAATT
ACATATGTCGATAATGATAACTATACAGCTGCAAGAGAAGTTGCAGAATATTTTATTTCTTTAGGGCATAAACGAATTGC
GTTTATCGGCGGTGGTTCCGATTTACTCGTAACAAAAGATCGTTTAGCTGGGATGAGTGATGCTTTAAAGTTAGCGGATA
TTCAGTTACCGAGTGAATATATTTTCCATTTAGATTTCTCAAGGGAAAGTGGTCAGCAAGCTGTAGAAGAATTAATGGGA
CTAAAAGAACCGCCAACAGCAATTATGGCTACAGACGATCTAATTGGTCTTGGTGTATTAAGTGCCCTTACAGCAAAAGG
GATTTCCGTACCGAAAGATGTTTCGTTAGTGAGCTTTAATAATGTGTTGTTATCCGAGATTGCGAGTCCACCTTTGACAA
CAGTAGATGTCAATATTTATCAATTAGGTTATGAAGCTGCAAAAGCATTAGTCGATAAAGTGGAACATTCAGAATCAAGT
TCAAAATGTATTGTGATTCCACATAAATTATTGAAACGTCAGACTTGTGAGGGTTGTGAAAAAAGCTAA

Upstream 100 bases:

>100_bases
ATAATTTAGTAAAACGCGAAAGAAATGGGACTTTTTTCTATAACCCACAAATTTGCAAAATCAAAATAGATGAAGAATGA
TGCAGAGAGGAGGAGAGGTT

Downstream 100 bases:

>100_bases
GAATGTTCATGAAGTGCACCTCAATTGTTAGACATAGTCTAACAATTGGAGGTGCACTTCATTTATCTCTTCGTTGTTTG
TTTGAAGAAATTTTCTAAAC

Product: alanine racemase

Products: NA

Alternate protein names: Maltose operon transcriptional repressor [H]

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MTVTIKDVAKKANVAPSTVSRVIADNPSISEKTKRRVRKVMSELGYHPNLNARSLANQTTKTIGLVMPSSANKAFQNPFF
PEVIRGISSFAHVEGYALYMSTGETEEEIFNGVIKMVQGRQIGGIILLYSRENDRIIQYLNEKNFPFVLIGKPYDKKDKI
TYVDNDNYTAAREVAEYFISLGHKRIAFIGGGSDLLVTKDRLAGMSDALKLADIQLPSEYIFHLDFSRESGQQAVEELMG
LKEPPTAIMATDDLIGLGVLSALTAKGISVPKDVSLVSFNNVLLSEIASPPLTTVDVNIYQLGYEAAKALVDKVEHSESS
SKCIVIPHKLLKRQTCEGCEKS

Sequences:

>Translated_342_residues
MTVTIKDVAKKANVAPSTVSRVIADNPSISEKTKRRVRKVMSELGYHPNLNARSLANQTTKTIGLVMPSSANKAFQNPFF
PEVIRGISSFAHVEGYALYMSTGETEEEIFNGVIKMVQGRQIGGIILLYSRENDRIIQYLNEKNFPFVLIGKPYDKKDKI
TYVDNDNYTAAREVAEYFISLGHKRIAFIGGGSDLLVTKDRLAGMSDALKLADIQLPSEYIFHLDFSRESGQQAVEELMG
LKEPPTAIMATDDLIGLGVLSALTAKGISVPKDVSLVSFNNVLLSEIASPPLTTVDVNIYQLGYEAAKALVDKVEHSESS
SKCIVIPHKLLKRQTCEGCEKS
>Mature_341_residues
TVTIKDVAKKANVAPSTVSRVIADNPSISEKTKRRVRKVMSELGYHPNLNARSLANQTTKTIGLVMPSSANKAFQNPFFP
EVIRGISSFAHVEGYALYMSTGETEEEIFNGVIKMVQGRQIGGIILLYSRENDRIIQYLNEKNFPFVLIGKPYDKKDKIT
YVDNDNYTAAREVAEYFISLGHKRIAFIGGGSDLLVTKDRLAGMSDALKLADIQLPSEYIFHLDFSRESGQQAVEELMGL
KEPPTAIMATDDLIGLGVLSALTAKGISVPKDVSLVSFNNVLLSEIASPPLTTVDVNIYQLGYEAAKALVDKVEHSESSS
KCIVIPHKLLKRQTCEGCEKS

Specific function: Transcriptional repressor of the maltosaccharide utilization operons malxCD and malMP [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=322, Percent_Identity=33.5403726708075, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI1787948, Length=333, Percent_Identity=30.03003003003, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1787580, Length=332, Percent_Identity=29.2168674698795, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1790194, Length=332, Percent_Identity=28.0120481927711, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1789202, Length=292, Percent_Identity=31.5068493150685, Blast_Score=141, Evalue=6e-35,
Organism=Escherichia coli, GI1789068, Length=304, Percent_Identity=29.6052631578947, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1788474, Length=298, Percent_Identity=29.8657718120805, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1787906, Length=341, Percent_Identity=25.2199413489736, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1786540, Length=337, Percent_Identity=27.893175074184, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1789456, Length=339, Percent_Identity=25.0737463126844, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI48994940, Length=329, Percent_Identity=25.531914893617, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790715, Length=345, Percent_Identity=25.5072463768116, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1786268, Length=295, Percent_Identity=24.7457627118644, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1790689, Length=340, Percent_Identity=24.4117647058824, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37622; Mature: 37490

Theoretical pI: Translated: 7.59; Mature: 7.59

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVTIKDVAKKANVAPSTVSRVIADNPSISEKTKRRVRKVMSELGYHPNLNARSLANQTT
CEEEHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
KTIGLVMPSSANKAFQNPFFPEVIRGISSFAHVEGYALYMSTGETEEEIFNGVIKMVQGR
HEEEEEECCCCCHHHCCCCHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHCCC
QIGGIILLYSRENDRIIQYLNEKNFPFVLIGKPYDKKDKITYVDNDNYTAAREVAEYFIS
CCCCEEEEEECCCCHHHHHHCCCCCCEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHH
LGHKRIAFIGGGSDLLVTKDRLAGMSDALKLADIQLPSEYIFHLDFSRESGQQAVEELMG
CCCCEEEEEECCCCEEEEHHHHCCHHHHHHHHHEECCCCEEEEEECCCCHHHHHHHHHHC
LKEPPTAIMATDDLIGLGVLSALTAKGISVPKDVSLVSFNNVLLSEIASPPLTTVDVNIY
CCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHCCCCCEEEEEEHH
QLGYEAAKALVDKVEHSESSSKCIVIPHKLLKRQTCEGCEKS
HHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TVTIKDVAKKANVAPSTVSRVIADNPSISEKTKRRVRKVMSELGYHPNLNARSLANQTT
EEEHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
KTIGLVMPSSANKAFQNPFFPEVIRGISSFAHVEGYALYMSTGETEEEIFNGVIKMVQGR
HEEEEEECCCCCHHHCCCCHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHCCC
QIGGIILLYSRENDRIIQYLNEKNFPFVLIGKPYDKKDKITYVDNDNYTAAREVAEYFIS
CCCCEEEEEECCCCHHHHHHCCCCCCEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHH
LGHKRIAFIGGGSDLLVTKDRLAGMSDALKLADIQLPSEYIFHLDFSRESGQQAVEELMG
CCCCEEEEEECCCCEEEEHHHHCCHHHHHHHHHEECCCCEEEEEECCCCHHHHHHHHHHC
LKEPPTAIMATDDLIGLGVLSALTAKGISVPKDVSLVSFNNVLLSEIASPPLTTVDVNIY
CCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHCCCCCEEEEEEHH
QLGYEAAKALVDKVEHSESSSKCIVIPHKLLKRQTCEGCEKS
HHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11463916 [H]