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The map label for this gene is kinB [H]

Identifier: 152976420

GI number: 152976420

Start: 2792374

End: 2793648

Strand: Reverse

Name: kinB [H]

Synonym: Bcer98_2708

Alternate gene names: 152976420

Gene position: 2793648-2792374 (Counterclockwise)

Preceding gene: 152976423

Following gene: 152976418

Centisome position: 68.35

GC content: 33.18

Gene sequence:

>1275_bases
ATGGAGCTAATCCGTGATTTAATGATCCAAGTTGCGATTATTATTTTGCCTCTATTTTTATATGAAGCAATCCGTCTCAA
TCATTATCAAAATATGCTTCCAAAGCCCAATTATTATTTTATTACATTTTTGTCCAGTGTTACACTTGTGCTTTCGATGA
CATATCCAATTTGTTTTGGAGAGATTTGTAATTTTAATTTTCATGCGATTCCAATTATGAGTAGTTTCTTATATGGTGGA
ATGATTGGTTTGATTCCAACTATGATTTTTCTTATATATGAATGGTTTTTACATGGTTTAAATTGGTTTCGGATCATAGA
GGTCATTGTGTTAGTCGTTATTCCATTATTATTATCCAAAAAGTGGACCGTCTTTCCAAGAAATAAAAAGCTTATTTTAT
CATTTATTGTGGCGTCTTTATATGTGCTAATTTGTCTCGTGATAGAAATATTTAATGTGTTATTAGGAACTGGATTTACT
TCTTCTACTTCACATGTATATAGCGGGTATATCGTTGCTTTATTTATTATGGTGATGACAATGGTATTTCAAGTATATTT
AACGGAGTACTTATATGAAAATGTATTACTGCGTGCAGAAATGCAAAAGTCAGAAAAATTAAATATCGTTAGTGAGCTAG
CTGCAAGTGTCGCACATGAAGTTAGAAATCCTCTTACTGTTGTGCGTGGTTTTATTCAATTACTCGATAGCACAGAAGAT
GTGAAAAATAAAGAGTATATGCGTCTTGTATTAGCTGAATTAGACCGAGCAGAACAAATTATTTCTGATTATTTAAATTT
AGCCAGACCACAAATTGAACAAAAAGAACATATTTGTTTATCTGCACAATTAATTGAAATGACTACGTTAATGTCTTCAT
TTGCAGCAATGCAAGGTGTGTATTTACAGGTTGAAATCTCTGAAAACCTTTATACGATAGGTGATAAGACGAAGCTGAAG
CAAGCGATTATGAATGTTGTAAAGAATGGAATCGAAGCGATTCAAGAAAACAAAGGCTATCTAAAGGTTACTGCTATTCA
GAAAGGTGACACCATTATTGTGCGAGTAAAAGATAGTGGAATTGGCATGACGAAAGAGCAACTAGCAAGACTTGGACAGC
CTTATTATTCTTTGAAAGAAAAAGGAACGGGCCTAGGGCTTATGGTAACATATCGTATTTTACAAGCCCATAACGGTACG
CTGGAATATAGTAGTGAAAGTGGGAAGGGGACAGAAGCAATTATTACATTACCAGCAGTTAAAAATAAGGAATAA

Upstream 100 bases:

>100_bases
AAATGATTTACAAATATAAATAGAAAAATCTAAATTTTGAAACAAAGTAGACTTTAAAATGATATAATCAAATCAAAATA
CATATAGGAGATGAAAGGCT

Downstream 100 bases:

>100_bases
AAGTTACCGTAAAAGGTAACTTTTTTTATATGAAAACTTGATTATTAGATAGTAAATTGTGACAAGGTAACACTCATGGA
TTTTTTTCTTGTTTTACACG

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MELIRDLMIQVAIIILPLFLYEAIRLNHYQNMLPKPNYYFITFLSSVTLVLSMTYPICFGEICNFNFHAIPIMSSFLYGG
MIGLIPTMIFLIYEWFLHGLNWFRIIEVIVLVVIPLLLSKKWTVFPRNKKLILSFIVASLYVLICLVIEIFNVLLGTGFT
SSTSHVYSGYIVALFIMVMTMVFQVYLTEYLYENVLLRAEMQKSEKLNIVSELAASVAHEVRNPLTVVRGFIQLLDSTED
VKNKEYMRLVLAELDRAEQIISDYLNLARPQIEQKEHICLSAQLIEMTTLMSSFAAMQGVYLQVEISENLYTIGDKTKLK
QAIMNVVKNGIEAIQENKGYLKVTAIQKGDTIIVRVKDSGIGMTKEQLARLGQPYYSLKEKGTGLGLMVTYRILQAHNGT
LEYSSESGKGTEAIITLPAVKNKE

Sequences:

>Translated_424_residues
MELIRDLMIQVAIIILPLFLYEAIRLNHYQNMLPKPNYYFITFLSSVTLVLSMTYPICFGEICNFNFHAIPIMSSFLYGG
MIGLIPTMIFLIYEWFLHGLNWFRIIEVIVLVVIPLLLSKKWTVFPRNKKLILSFIVASLYVLICLVIEIFNVLLGTGFT
SSTSHVYSGYIVALFIMVMTMVFQVYLTEYLYENVLLRAEMQKSEKLNIVSELAASVAHEVRNPLTVVRGFIQLLDSTED
VKNKEYMRLVLAELDRAEQIISDYLNLARPQIEQKEHICLSAQLIEMTTLMSSFAAMQGVYLQVEISENLYTIGDKTKLK
QAIMNVVKNGIEAIQENKGYLKVTAIQKGDTIIVRVKDSGIGMTKEQLARLGQPYYSLKEKGTGLGLMVTYRILQAHNGT
LEYSSESGKGTEAIITLPAVKNKE
>Mature_424_residues
MELIRDLMIQVAIIILPLFLYEAIRLNHYQNMLPKPNYYFITFLSSVTLVLSMTYPICFGEICNFNFHAIPIMSSFLYGG
MIGLIPTMIFLIYEWFLHGLNWFRIIEVIVLVVIPLLLSKKWTVFPRNKKLILSFIVASLYVLICLVIEIFNVLLGTGFT
SSTSHVYSGYIVALFIMVMTMVFQVYLTEYLYENVLLRAEMQKSEKLNIVSELAASVAHEVRNPLTVVRGFIQLLDSTED
VKNKEYMRLVLAELDRAEQIISDYLNLARPQIEQKEHICLSAQLIEMTTLMSSFAAMQGVYLQVEISENLYTIGDKTKLK
QAIMNVVKNGIEAIQENKGYLKVTAIQKGDTIIVRVKDSGIGMTKEQLARLGQPYYSLKEKGTGLGLMVTYRILQAHNGT
LEYSSESGKGTEAIITLPAVKNKE

Specific function: Phosphorylates the sporulation-regulatory proteins spo0A and spo0F. Spo0F is required for the kinB activity [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=283, Percent_Identity=29.6819787985866, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1788549, Length=236, Percent_Identity=33.0508474576271, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI145693157, Length=292, Percent_Identity=26.3698630136986, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1789149, Length=233, Percent_Identity=27.4678111587983, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87081816, Length=244, Percent_Identity=28.6885245901639, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI48994928, Length=257, Percent_Identity=24.9027237354086, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1786783, Length=232, Percent_Identity=28.0172413793103, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790300, Length=282, Percent_Identity=25.886524822695, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1788393, Length=239, Percent_Identity=22.1757322175732, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1786600, Length=218, Percent_Identity=23.394495412844, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1789808, Length=222, Percent_Identity=26.1261261261261, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1790551, Length=216, Percent_Identity=27.7777777777778, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788713, Length=243, Percent_Identity=25.9259259259259, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789403, Length=212, Percent_Identity=25.9433962264151, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48200; Mature: 48200

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELIRDLMIQVAIIILPLFLYEAIRLNHYQNMLPKPNYYFITFLSSVTLVLSMTYPICFG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHH
EICNFNFHAIPIMSSFLYGGMIGLIPTMIFLIYEWFLHGLNWFRIIEVIVLVVIPLLLSK
HHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
KWTVFPRNKKLILSFIVASLYVLICLVIEIFNVLLGTGFTSSTSHVYSGYIVALFIMVMT
CCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
MVFQVYLTEYLYENVLLRAEMQKSEKLNIVSELAASVAHEVRNPLTVVRGFIQLLDSTED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHH
VKNKEYMRLVLAELDRAEQIISDYLNLARPQIEQKEHICLSAQLIEMTTLMSSFAAMQGV
HCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
YLQVEISENLYTIGDKTKLKQAIMNVVKNGIEAIQENKGYLKVTAIQKGDTIIVRVKDSG
EEEEEECCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEEEEECCC
IGMTKEQLARLGQPYYSLKEKGTGLGLMVTYRILQAHNGTLEYSSESGKGTEAIITLPAV
CCCCHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCEEEEEECCC
KNKE
CCCC
>Mature Secondary Structure
MELIRDLMIQVAIIILPLFLYEAIRLNHYQNMLPKPNYYFITFLSSVTLVLSMTYPICFG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHH
EICNFNFHAIPIMSSFLYGGMIGLIPTMIFLIYEWFLHGLNWFRIIEVIVLVVIPLLLSK
HHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
KWTVFPRNKKLILSFIVASLYVLICLVIEIFNVLLGTGFTSSTSHVYSGYIVALFIMVMT
CCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
MVFQVYLTEYLYENVLLRAEMQKSEKLNIVSELAASVAHEVRNPLTVVRGFIQLLDSTED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHH
VKNKEYMRLVLAELDRAEQIISDYLNLARPQIEQKEHICLSAQLIEMTTLMSSFAAMQGV
HCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
YLQVEISENLYTIGDKTKLKQAIMNVVKNGIEAIQENKGYLKVTAIQKGDTIIVRVKDSG
EEEEEECCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEEEEECCC
IGMTKEQLARLGQPYYSLKEKGTGLGLMVTYRILQAHNGTLEYSSESGKGTEAIITLPAV
CCCCHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCEEEEEECCC
KNKE
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8497199; 9274030; 9384377 [H]