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The map label for this gene is purL [H]

Identifier: 152974114

GI number: 152974114

Start: 312963

End: 315182

Strand: Direct

Name: purL [H]

Synonym: Bcer98_0273

Alternate gene names: 152974114

Gene position: 312963-315182 (Clockwise)

Preceding gene: 152974113

Following gene: 152974115

Centisome position: 7.66

GC content: 40.63

Gene sequence:

>2220_bases
ATGTCGTTAATGCTTGAACCAAATCCAACACAAATTAAAGAAGAACGTATATATGCGGAAATGGGGTTAACAGACGAAGA
GTTTGCCATGATTGAAAAGATTTTAGGACGTCTGCCGAACTATACGGAAACAGGGCTTTTCTCTGTTATGTGGTCAGAGC
ATTGTAGTTATAAAAACTCAAAACCAGTTCTTCGCAAGTTCCCAACAACAGGAGAACGTGTATTACAAGGACCTGGAGAA
GGCGCAGGTATTGTAGATATTGGTGATAATCAAGCAGTTGTATTTAAAATGGAAAGTCACAATCATCCTTCGGCAATTGA
GCCGTATCAAGGTGCAGCAACAGGGGTTGGCGGTATTATTCGTGATATATTCTCTATGGGAGCACGTCCGGTTGCATTAT
TGAACTCACTGCGCTTCGGTGAACTCCAATCACCACGCGTGAAGTATTTATTTGAAGAAGTAGTTGCAGGGATTGCAGGA
TACGGTAACTGTATTGGTATTCCAACTGTTGGCGGAGAAGTACAATTTGATCCATGTTATGAAGGAAACCCACTTGTCAA
TGCAATGTGCGTTGGGTTAATTCATCATGAAGATATAAAAAAAGGGCAAGCGCACGGTGCTGGTAACACGGTTATGTATG
TCGGTGCTTCAACAGGACGAGACGGTATTCATGGTGCAACTTTCGCATCAGAAGAACTATCTGAGAGTTCAGAAGCAAAA
CGCCCAGCAGTACAAGTAGGCGATCCGTTTATGGAGAAACTTCTTATTGAAGCATGCTTAGAGTTAATCCAATCTGATGC
GCTTGTTGGAATTCAAGATATGGGCGCTGCGGGCTTAACATCATCTTCTGCGGAAATGGCAAGTAAAGCGGGAATGGGTA
TTGAAATGTATTTAGACGATGTGCCACAGCGTGAAACAGGTATGACACCATATGAAATGATGTTATCTGAATCACAGGAA
CGTATGTTGATTGTGGTGAAAAAAGGTAGAGAGCAAGAAGTTGTAGAGTTATTTGAAAAGTATGGCTTAGCGGCAGTTGC
GATGGGAAAAGTAACGGAAGATAAAATGCTTCGTTTATTCCATAAAGGTGAAATGGTAGCAGAAGTACCTGCGGATGCAT
TAGCAGAAGAAGCGCCAATTTATCATAAACCTTCAAAAGAGGCAGCATATTTTAGGGAATTTCAAGAAATGAAAATGAAG
ACGCCAAAAGTAGATAACTATAAAGAAACATTACTAGCTTTATTACAACAACCAACGATTGCAAGTAAAGAATGGGTATA
TGATCAGTATGATTATCAAGTACGCACAAGTACTGTTGTTACACCAGGATCAGATGCAGCGGTGGTGCGAGTACGTGGTA
CAGAGAAGGCATTAGCAATCACAACGGACTGTAACTCTCGTTATATTTACTTAGATCCTGAAACGGGCGGTAAAATTGCA
GTAGCAGAAGCTGCGCGTAATATTGTATGTTCTGGCGGAGAACCACTTGCAATCACAGATTGCTTAAATTTTGGTAATCC
AGAGAAACCAGAAATTTTCTGGCAAATTGAGAAATCAGTAGATGGTATGAGCGAAGCTTGTCGTACATTACAAACTCCAG
TTATTGGTGGAAATGTATCAATGTACAACGAGCGCAGCGGTGAAGCTGTATATCCAACACCAACTGTTGGAATGGTTGGG
CTTGTTCACGATTTAAAACATGTAACAACACAAGAATTTAAGCAAGCTGGGGATCTTATTTATGTTATGGGTGAAACGAA
AGCTGAATTTGGTGGAAGTGAATTACAGAAGATGATGTACGGTAAAATCTTCGGTCAATCACCAAGTATTGATTTAGAAG
TAGAAGCAAAACGTCAAAAACAATTACTAGAAGCAATTCAGGCGGGACTTGTTCAATCGGCACATGACGTTGCAGAAGGC
GGATTAGCAGTTGCGATTGCTGAAAGTGCAATCGGTGCGAAAGGATTAGGTGCTACTGTGAAATTAGCTGGGGAGGCAAC
AGCGGCATTATTCGCAGAATCACAATCTCGTTTTGTTGTAACAGTAAAACGTGAACAACAAGAAGCGTTTGAAAAAGTAG
TAGAAGCAATTCAAGTTGGTGAAGTCACAAATACAAATGAAGTAACAATTCATAATGAAGAAAATGAAGTACTACTTACA
GCAAATGTTGATGAAATGAGAAAGGCTTGGAAAGGGGCAATCCCATGCTTGCTGAAATAA

Upstream 100 bases:

>100_bases
GGCATGATGCCACACCCAGAGCGTGCTGTGAATGAAATTCTTGGCGGTGCAGAAGGGTTAAAAGTCTTTCAATCTATTTT
GAAATATTGGAGGGAAACAT

Downstream 100 bases:

>100_bases
AGGGGTTAAATGAAGAATGTGGCATCTTCGGAATTTGGGGGCATGAAAATGCAGCACAAGTTACGTACTACGGATTGCAT
AGTTTACAGCACCGTGGGCA

Product: phosphoribosylformylglycinamidine synthase II

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase II; FGAM synthase II [H]

Number of amino acids: Translated: 739; Mature: 738

Protein sequence:

>739_residues
MSLMLEPNPTQIKEERIYAEMGLTDEEFAMIEKILGRLPNYTETGLFSVMWSEHCSYKNSKPVLRKFPTTGERVLQGPGE
GAGIVDIGDNQAVVFKMESHNHPSAIEPYQGAATGVGGIIRDIFSMGARPVALLNSLRFGELQSPRVKYLFEEVVAGIAG
YGNCIGIPTVGGEVQFDPCYEGNPLVNAMCVGLIHHEDIKKGQAHGAGNTVMYVGASTGRDGIHGATFASEELSESSEAK
RPAVQVGDPFMEKLLIEACLELIQSDALVGIQDMGAAGLTSSSAEMASKAGMGIEMYLDDVPQRETGMTPYEMMLSESQE
RMLIVVKKGREQEVVELFEKYGLAAVAMGKVTEDKMLRLFHKGEMVAEVPADALAEEAPIYHKPSKEAAYFREFQEMKMK
TPKVDNYKETLLALLQQPTIASKEWVYDQYDYQVRTSTVVTPGSDAAVVRVRGTEKALAITTDCNSRYIYLDPETGGKIA
VAEAARNIVCSGGEPLAITDCLNFGNPEKPEIFWQIEKSVDGMSEACRTLQTPVIGGNVSMYNERSGEAVYPTPTVGMVG
LVHDLKHVTTQEFKQAGDLIYVMGETKAEFGGSELQKMMYGKIFGQSPSIDLEVEAKRQKQLLEAIQAGLVQSAHDVAEG
GLAVAIAESAIGAKGLGATVKLAGEATAALFAESQSRFVVTVKREQQEAFEKVVEAIQVGEVTNTNEVTIHNEENEVLLT
ANVDEMRKAWKGAIPCLLK

Sequences:

>Translated_739_residues
MSLMLEPNPTQIKEERIYAEMGLTDEEFAMIEKILGRLPNYTETGLFSVMWSEHCSYKNSKPVLRKFPTTGERVLQGPGE
GAGIVDIGDNQAVVFKMESHNHPSAIEPYQGAATGVGGIIRDIFSMGARPVALLNSLRFGELQSPRVKYLFEEVVAGIAG
YGNCIGIPTVGGEVQFDPCYEGNPLVNAMCVGLIHHEDIKKGQAHGAGNTVMYVGASTGRDGIHGATFASEELSESSEAK
RPAVQVGDPFMEKLLIEACLELIQSDALVGIQDMGAAGLTSSSAEMASKAGMGIEMYLDDVPQRETGMTPYEMMLSESQE
RMLIVVKKGREQEVVELFEKYGLAAVAMGKVTEDKMLRLFHKGEMVAEVPADALAEEAPIYHKPSKEAAYFREFQEMKMK
TPKVDNYKETLLALLQQPTIASKEWVYDQYDYQVRTSTVVTPGSDAAVVRVRGTEKALAITTDCNSRYIYLDPETGGKIA
VAEAARNIVCSGGEPLAITDCLNFGNPEKPEIFWQIEKSVDGMSEACRTLQTPVIGGNVSMYNERSGEAVYPTPTVGMVG
LVHDLKHVTTQEFKQAGDLIYVMGETKAEFGGSELQKMMYGKIFGQSPSIDLEVEAKRQKQLLEAIQAGLVQSAHDVAEG
GLAVAIAESAIGAKGLGATVKLAGEATAALFAESQSRFVVTVKREQQEAFEKVVEAIQVGEVTNTNEVTIHNEENEVLLT
ANVDEMRKAWKGAIPCLLK
>Mature_738_residues
SLMLEPNPTQIKEERIYAEMGLTDEEFAMIEKILGRLPNYTETGLFSVMWSEHCSYKNSKPVLRKFPTTGERVLQGPGEG
AGIVDIGDNQAVVFKMESHNHPSAIEPYQGAATGVGGIIRDIFSMGARPVALLNSLRFGELQSPRVKYLFEEVVAGIAGY
GNCIGIPTVGGEVQFDPCYEGNPLVNAMCVGLIHHEDIKKGQAHGAGNTVMYVGASTGRDGIHGATFASEELSESSEAKR
PAVQVGDPFMEKLLIEACLELIQSDALVGIQDMGAAGLTSSSAEMASKAGMGIEMYLDDVPQRETGMTPYEMMLSESQER
MLIVVKKGREQEVVELFEKYGLAAVAMGKVTEDKMLRLFHKGEMVAEVPADALAEEAPIYHKPSKEAAYFREFQEMKMKT
PKVDNYKETLLALLQQPTIASKEWVYDQYDYQVRTSTVVTPGSDAAVVRVRGTEKALAITTDCNSRYIYLDPETGGKIAV
AEAARNIVCSGGEPLAITDCLNFGNPEKPEIFWQIEKSVDGMSEACRTLQTPVIGGNVSMYNERSGEAVYPTPTVGMVGL
VHDLKHVTTQEFKQAGDLIYVMGETKAEFGGSELQKMMYGKIFGQSPSIDLEVEAKRQKQLLEAIQAGLVQSAHDVAEGG
LAVAIAESAIGAKGLGATVKLAGEATAALFAESQSRFVVTVKREQQEAFEKVVEAIQVGEVTNTNEVTIHNEENEVLLTA
NVDEMRKAWKGAIPCLLK

Specific function: Unknown

COG id: COG0046

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGAMS family [H]

Homologues:

Organism=Homo sapiens, GI31657129, Length=721, Percent_Identity=23.7170596393897, Blast_Score=113, Evalue=5e-25,
Organism=Escherichia coli, GI48994899, Length=771, Percent_Identity=25.5512321660182, Blast_Score=140, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17553022, Length=679, Percent_Identity=21.5022091310751, Blast_Score=101, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6321498, Length=728, Percent_Identity=22.3901098901099, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24582111, Length=638, Percent_Identity=23.9811912225705, Blast_Score=106, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24582109, Length=638, Percent_Identity=23.9811912225705, Blast_Score=106, Evalue=6e-23,
Organism=Drosophila melanogaster, GI17137292, Length=638, Percent_Identity=23.9811912225705, Blast_Score=106, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR010074
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 80335; Mature: 80203

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLMLEPNPTQIKEERIYAEMGLTDEEFAMIEKILGRLPNYTETGLFSVMWSEHCSYKNS
CCEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCC
KPVLRKFPTTGERVLQGPGEGAGIVDIGDNQAVVFKMESHNHPSAIEPYQGAATGVGGII
CCHHHHCCCCCHHHHCCCCCCCCEEEECCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHH
RDIFSMGARPVALLNSLRFGELQSPRVKYLFEEVVAGIAGYGNCIGIPTVGGEVQFDPCY
HHHHHCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCCEEEECCCC
EGNPLVNAMCVGLIHHEDIKKGQAHGAGNTVMYVGASTGRDGIHGATFASEELSESSEAK
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHC
RPAVQVGDPFMEKLLIEACLELIQSDALVGIQDMGAAGLTSSSAEMASKAGMGIEMYLDD
CCCEECCCHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCHHHHHHHCCCCEEEEECC
VPQRETGMTPYEMMLSESQERMLIVVKKGREQEVVELFEKYGLAAVAMGKVTEDKMLRLF
CCCCCCCCCHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHH
HKGEMVAEVPADALAEEAPIYHKPSKEAAYFREFQEMKMKTPKVDNYKETLLALLQQPTI
HCCCEEECCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCC
ASKEWVYDQYDYQVRTSTVVTPGSDAAVVRVRGTEKALAITTDCNSRYIYLDPETGGKIA
CCCCCCCCCCCEEEEEEEEECCCCCEEEEEEECCCCEEEEEECCCCEEEEECCCCCCEEE
VAEAARNIVCSGGEPLAITDCLNFGNPEKPEIFWQIEKSVDGMSEACRTLQTPVIGGNVS
EEHHHCCEEECCCCCEEEEEHHCCCCCCCCEEEEEEHHHHCHHHHHHHHHCCCEECCCEE
MYNERSGEAVYPTPTVGMVGLVHDLKHVTTQEFKQAGDLIYVMGETKAEFGGSELQKMMY
EECCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHCCHHHHHHHHH
GKIFGQSPSIDLEVEAKRQKQLLEAIQAGLVQSAHDVAEGGLAVAIAESAIGAKGLGATV
HHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHCCCCCCCCEE
KLAGEATAALFAESQSRFVVTVKREQQEAFEKVVEAIQVGEVTNTNEVTIHNEENEVLLT
EECCCHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEE
ANVDEMRKAWKGAIPCLLK
ECHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SLMLEPNPTQIKEERIYAEMGLTDEEFAMIEKILGRLPNYTETGLFSVMWSEHCSYKNS
CEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCC
KPVLRKFPTTGERVLQGPGEGAGIVDIGDNQAVVFKMESHNHPSAIEPYQGAATGVGGII
CCHHHHCCCCCHHHHCCCCCCCCEEEECCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHH
RDIFSMGARPVALLNSLRFGELQSPRVKYLFEEVVAGIAGYGNCIGIPTVGGEVQFDPCY
HHHHHCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCCEEEECCCC
EGNPLVNAMCVGLIHHEDIKKGQAHGAGNTVMYVGASTGRDGIHGATFASEELSESSEAK
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHC
RPAVQVGDPFMEKLLIEACLELIQSDALVGIQDMGAAGLTSSSAEMASKAGMGIEMYLDD
CCCEECCCHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCHHHHHHHCCCCEEEEECC
VPQRETGMTPYEMMLSESQERMLIVVKKGREQEVVELFEKYGLAAVAMGKVTEDKMLRLF
CCCCCCCCCHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHH
HKGEMVAEVPADALAEEAPIYHKPSKEAAYFREFQEMKMKTPKVDNYKETLLALLQQPTI
HCCCEEECCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCC
ASKEWVYDQYDYQVRTSTVVTPGSDAAVVRVRGTEKALAITTDCNSRYIYLDPETGGKIA
CCCCCCCCCCCEEEEEEEEECCCCCEEEEEEECCCCEEEEEECCCCEEEEECCCCCCEEE
VAEAARNIVCSGGEPLAITDCLNFGNPEKPEIFWQIEKSVDGMSEACRTLQTPVIGGNVS
EEHHHCCEEECCCCCEEEEEHHCCCCCCCCEEEEEEHHHHCHHHHHHHHHCCCEECCCEE
MYNERSGEAVYPTPTVGMVGLVHDLKHVTTQEFKQAGDLIYVMGETKAEFGGSELQKMMY
EECCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHCCHHHHHHHHH
GKIFGQSPSIDLEVEAKRQKQLLEAIQAGLVQSAHDVAEGGLAVAIAESAIGAKGLGATV
HHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHCCCCCCCCEE
KLAGEATAALFAESQSRFVVTVKREQQEAFEKVVEAIQVGEVTNTNEVTIHNEENEVLLT
EECCCHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEE
ANVDEMRKAWKGAIPCLLK
ECHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA