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The map label for this gene is purQ [H]

Identifier: 152974113

GI number: 152974113

Start: 312296

End: 312979

Strand: Direct

Name: purQ [H]

Synonym: Bcer98_0272

Alternate gene names: 152974113

Gene position: 312296-312979 (Clockwise)

Preceding gene: 152974112

Following gene: 152974114

Centisome position: 7.64

GC content: 37.72

Gene sequence:

>684_bases
GTGAAATTTGCCGTAATCGTTTTTCCAGGTTCGAACTGTGATGTTGATATGTTTCATGCAATTAAAGATGAGCTTGGTGA
AGATGTAGATTATGTTTGGCATGATGCAGAGAACTTAGACGAATATGATGCGATTCTTTTACCAGGTGGATTCTCTTATG
GTGATTACCTTCGCTGCGGTGCCATTTCTCGATTTGCGAATGCAATGAAAGCAGTGCAAAAAGCTGCTGAGCAAGGAAAG
CCTATTTTAGGCGTGTGTAATGGATTCCAGATTCTTGTTGAATCAGGATTATTACCAGGGGTATTGATACGAAATCAAAA
CTTAAAATTCATGTGCCGAACTGTTCCGTTACGTGTTGAAAATAATGAAACGATGTTTACATCACAATATAACAAGGGGG
AAATCATTCATATCCCAATTGCACATGGTGAAGGAAATTATTATTGTGATGAAGCAACTCTTAAAAAATTAGAGCAGAAG
AATCAAATTGTATTCCGTTATGTAGACAATCCAAACGGAAGTGTTTCAGATATTGCAGGTATTGTAAATGAAAAAGGTAA
TGTGCTTGGCATGATGCCACACCCAGAGCGTGCTGTGAATGAAATTCTTGGCGGTGCAGAAGGGTTAAAAGTCTTTCAAT
CTATTTTGAAATATTGGAGGGAAACATATGTCGTTAATGCTTGA

Upstream 100 bases:

>100_bases
TAACTGATCTTGATAGAAAAGTAAAAGAAATGTGTGAAAAACTATTAGCAAACGTTGTAATGGAAGATTTCCGTTATGAA
ATTGAGGAGGTTGTCGCACA

Downstream 100 bases:

>100_bases
ACCAAATCCAACACAAATTAAAGAAGAACGTATATATGCGGAAATGGGGTTAACAGACGAAGAGTTTGCCATGATTGAAA
AGATTTTAGGACGTCTGCCG

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MKFAVIVFPGSNCDVDMFHAIKDELGEDVDYVWHDAENLDEYDAILLPGGFSYGDYLRCGAISRFANAMKAVQKAAEQGK
PILGVCNGFQILVESGLLPGVLIRNQNLKFMCRTVPLRVENNETMFTSQYNKGEIIHIPIAHGEGNYYCDEATLKKLEQK
NQIVFRYVDNPNGSVSDIAGIVNEKGNVLGMMPHPERAVNEILGGAEGLKVFQSILKYWRETYVVNA

Sequences:

>Translated_227_residues
MKFAVIVFPGSNCDVDMFHAIKDELGEDVDYVWHDAENLDEYDAILLPGGFSYGDYLRCGAISRFANAMKAVQKAAEQGK
PILGVCNGFQILVESGLLPGVLIRNQNLKFMCRTVPLRVENNETMFTSQYNKGEIIHIPIAHGEGNYYCDEATLKKLEQK
NQIVFRYVDNPNGSVSDIAGIVNEKGNVLGMMPHPERAVNEILGGAEGLKVFQSILKYWRETYVVNA
>Mature_227_residues
MKFAVIVFPGSNCDVDMFHAIKDELGEDVDYVWHDAENLDEYDAILLPGGFSYGDYLRCGAISRFANAMKAVQKAAEQGK
PILGVCNGFQILVESGLLPGVLIRNQNLKFMCRTVPLRVENNETMFTSQYNKGEIIHIPIAHGEGNYYCDEATLKKLEQK
NQIVFRYVDNPNGSVSDIAGIVNEKGNVLGMMPHPERAVNEILGGAEGLKVFQSILKYWRETYVVNA

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI31657129, Length=242, Percent_Identity=28.099173553719, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI48994899, Length=246, Percent_Identity=31.3008130081301, Blast_Score=85, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17553022, Length=235, Percent_Identity=26.3829787234043, Blast_Score=74, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6321498, Length=240, Percent_Identity=29.1666666666667, Blast_Score=73, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24582111, Length=230, Percent_Identity=28.695652173913, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24582109, Length=230, Percent_Identity=28.695652173913, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI17137292, Length=230, Percent_Identity=28.695652173913, Blast_Score=83, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR010075 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 25312; Mature: 25312

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFAVIVFPGSNCDVDMFHAIKDELGEDVDYVWHDAENLDEYDAILLPGGFSYGDYLRCG
CEEEEEEECCCCCCHHHHHHHHHHHCCCHHEEECCCCCCCCCCEEEECCCCCCCCHHHHH
AISRFANAMKAVQKAAEQGKPILGVCNGFQILVESGLLPGVLIRNQNLKFMCRTVPLRVE
HHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHCCCCCCEEEECCCCEEEEEEEEEEEC
NNETMFTSQYNKGEIIHIPIAHGEGNYYCDEATLKKLEQKNQIVFRYVDNPNGSVSDIAG
CCCEEEEECCCCCCEEEEEEEECCCCEEECHHHHHHHHHCCCEEEEEECCCCCCHHHHHH
IVNEKGNVLGMMPHPERAVNEILGGAEGLKVFQSILKYWRETYVVNA
HHCCCCCEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHEECCC
>Mature Secondary Structure
MKFAVIVFPGSNCDVDMFHAIKDELGEDVDYVWHDAENLDEYDAILLPGGFSYGDYLRCG
CEEEEEEECCCCCCHHHHHHHHHHHCCCHHEEECCCCCCCCCCEEEECCCCCCCCHHHHH
AISRFANAMKAVQKAAEQGKPILGVCNGFQILVESGLLPGVLIRNQNLKFMCRTVPLRVE
HHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHCCCCCCEEEECCCCEEEEEEEEEEEC
NNETMFTSQYNKGEIIHIPIAHGEGNYYCDEATLKKLEQKNQIVFRYVDNPNGSVSDIAG
CCCEEEEECCCCCCEEEEEEEECCCCEEECHHHHHHHHHCCCEEEEEECCCCCCHHHHHH
IVNEKGNVLGMMPHPERAVNEILGGAEGLKVFQSILKYWRETYVVNA
HHCCCCCEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA