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The map label for this gene is appB [H]

Identifier: 152970569

GI number: 152970569

Start: 2213366

End: 2214325

Strand: Direct

Name: appB [H]

Synonym: KPN_02020

Alternate gene names: 152970569

Gene position: 2213366-2214325 (Clockwise)

Preceding gene: 152970568

Following gene: 152970570

Centisome position: 41.64

GC content: 60.62

Gene sequence:

>960_bases
ATGAGAAATTTCATCCTGAGGCGCCTGCTGCAAACGCTGCCGATGCTGCTGCTGGCCTCCTTCATTATTTTTTTGCTGTT
TGCCAAAACCCCCGGCGACTTTATCGATGGCAATATCACCCTGACCGCTGCCCGCGCCGCGGAGCTGAAGGCGATCTACG
GCCTCGACCAGCCGCTGTTGACCCGCTACCTCCACTGGCTGGGACAGTTGCTGCGCGGTGATTTAGGCTTTTCGCTGCAG
TATCAGATCCCGGTCAGCCAGTTGCTCAACCAGTACATCTGGAACTCTTTTCTGCTGGCCAGCGTCGCGCTGGTCTTTTA
CTGGGGCATCGGCCTGGCGGTGGGCGTGGTTTCTGCCCTGCGCCCTGGCTCCTGGTTTGATCATCTGGTGAGCGTCGCGG
TGTTTGCCGCCATGTCGTTCCCCACCTTTTTCCTCTGCCTGCTGCTGATTAAATGGTTCGCCGTCGATCTCCACTGGCTG
CCGGTAGGCGGGATGACCAATACCGGCAGCGACGAGAGCGGCTGGCAGTATGTGCTGCAGGTGGCTGCCCATCTGGCGCT
GCCGGTGCTGGCGCTGGTGATGCTGCAGGCGGGCAGCCTGACGCGCTATGTGCGCGCCAGTATGCTCGACGTGGTGAAAA
TGGATTTTATCCGTACCGCCCGCGCCAAGGGGTTGCAGGAGCGCACGGTGATCCTCAAACATGCCCTGCGCAACGCCCTG
CTGCCGATTATCACCCTGCTGGGCTTCGAGCTGCCGGGGCTGTTCTCCGGGGCGATCATTACCGAAAAGGTATTCAACTG
GCCGGGGGCGGGCCACATTCATATCGACTCGCTGGCCGCCCGCGACTATCCGGTACTGATGGGGTTTACCCTGTTTCTGG
CGGTGCTGACGATAGTCGGGAATCTGCTCGCCGACGTGCTGTACGCCTGGGCCGATCCGCGTATTCGGGTGAGGTCATAA

Upstream 100 bases:

>100_bases
CCGGATATCTACAACGGCCTGACCGGCAGCCTGCCGGATGTAAAAATCGTCAAATAAATCCCTGGCCGCCGGGTTAACCG
GCGGCTGATGTGAGACCGTC

Downstream 100 bases:

>100_bases
TGATCCTGTCTTACTTAGTTTCCCGTCGCCGCCAGCGGCAGGCGGCTATCCCGGCGCTGGCGCACAATACCCCCTCTCCC
TGGCGCCAGGGGTGGCGACA

Product: oligopeptide ABC transporter, permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MRNFILRRLLQTLPMLLLASFIIFLLFAKTPGDFIDGNITLTAARAAELKAIYGLDQPLLTRYLHWLGQLLRGDLGFSLQ
YQIPVSQLLNQYIWNSFLLASVALVFYWGIGLAVGVVSALRPGSWFDHLVSVAVFAAMSFPTFFLCLLLIKWFAVDLHWL
PVGGMTNTGSDESGWQYVLQVAAHLALPVLALVMLQAGSLTRYVRASMLDVVKMDFIRTARAKGLQERTVILKHALRNAL
LPIITLLGFELPGLFSGAIITEKVFNWPGAGHIHIDSLAARDYPVLMGFTLFLAVLTIVGNLLADVLYAWADPRIRVRS

Sequences:

>Translated_319_residues
MRNFILRRLLQTLPMLLLASFIIFLLFAKTPGDFIDGNITLTAARAAELKAIYGLDQPLLTRYLHWLGQLLRGDLGFSLQ
YQIPVSQLLNQYIWNSFLLASVALVFYWGIGLAVGVVSALRPGSWFDHLVSVAVFAAMSFPTFFLCLLLIKWFAVDLHWL
PVGGMTNTGSDESGWQYVLQVAAHLALPVLALVMLQAGSLTRYVRASMLDVVKMDFIRTARAKGLQERTVILKHALRNAL
LPIITLLGFELPGLFSGAIITEKVFNWPGAGHIHIDSLAARDYPVLMGFTLFLAVLTIVGNLLADVLYAWADPRIRVRS
>Mature_319_residues
MRNFILRRLLQTLPMLLLASFIIFLLFAKTPGDFIDGNITLTAARAAELKAIYGLDQPLLTRYLHWLGQLLRGDLGFSLQ
YQIPVSQLLNQYIWNSFLLASVALVFYWGIGLAVGVVSALRPGSWFDHLVSVAVFAAMSFPTFFLCLLLIKWFAVDLHWL
PVGGMTNTGSDESGWQYVLQVAAHLALPVLALVMLQAGSLTRYVRASMLDVVKMDFIRTARAKGLQERTVILKHALRNAL
LPIITLLGFELPGLFSGAIITEKVFNWPGAGHIHIDSLAARDYPVLMGFTLFLAVLTIVGNLLADVLYAWADPRIRVRS

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=324, Percent_Identity=37.037037037037, Blast_Score=207, Evalue=6e-55,
Organism=Escherichia coli, GI1789965, Length=339, Percent_Identity=36.5781710914454, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1787497, Length=320, Percent_Identity=35, Blast_Score=192, Evalue=3e-50,
Organism=Escherichia coli, GI1789888, Length=321, Percent_Identity=36.1370716510903, Blast_Score=177, Evalue=9e-46,
Organism=Escherichia coli, GI1787761, Length=311, Percent_Identity=35.3697749196142, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1788504, Length=361, Percent_Identity=27.9778393351801, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787550, Length=272, Percent_Identity=27.5735294117647, Blast_Score=125, Evalue=5e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35484; Mature: 35484

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNFILRRLLQTLPMLLLASFIIFLLFAKTPGDFIDGNITLTAARAAELKAIYGLDQPLL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHCCCHHHH
TRYLHWLGQLLRGDLGFSLQYQIPVSQLLNQYIWNSFLLASVALVFYWGIGLAVGVVSAL
HHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RPGSWFDHLVSVAVFAAMSFPTFFLCLLLIKWFAVDLHWLPVGGMTNTGSDESGWQYVLQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCHHHHHHHH
VAAHLALPVLALVMLQAGSLTRYVRASMLDVVKMDFIRTARAKGLQERTVILKHALRNAL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
LPIITLLGFELPGLFSGAIITEKVFNWPGAGHIHIDSLAARDYPVLMGFTLFLAVLTIVG
HHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCEEECCHHCCCCHHHHHHHHHHHHHHHHH
NLLADVLYAWADPRIRVRS
HHHHHHHHHHCCCCEEECC
>Mature Secondary Structure
MRNFILRRLLQTLPMLLLASFIIFLLFAKTPGDFIDGNITLTAARAAELKAIYGLDQPLL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHCCCHHHH
TRYLHWLGQLLRGDLGFSLQYQIPVSQLLNQYIWNSFLLASVALVFYWGIGLAVGVVSAL
HHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RPGSWFDHLVSVAVFAAMSFPTFFLCLLLIKWFAVDLHWLPVGGMTNTGSDESGWQYVLQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCHHHHHHHH
VAAHLALPVLALVMLQAGSLTRYVRASMLDVVKMDFIRTARAKGLQERTVILKHALRNAL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
LPIITLLGFELPGLFSGAIITEKVFNWPGAGHIHIDSLAARDYPVLMGFTLFLAVLTIVG
HHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCEEECCHHCCCCHHHHHHHHHHHHHHHHH
NLLADVLYAWADPRIRVRS
HHHHHHHHHHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]