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The map label for this gene is gst [H]

Identifier: 152970525

GI number: 152970525

Start: 2169677

End: 2170282

Strand: Direct

Name: gst [H]

Synonym: KPN_01973

Alternate gene names: 152970525

Gene position: 2169677-2170282 (Clockwise)

Preceding gene: 152970524

Following gene: 152970531

Centisome position: 40.82

GC content: 57.1

Gene sequence:

>606_bases
ATGAAACTGTTCTACAAACCCGGCGCCTGTTCCCTTGCCTCGCATATTGCCCTGCGCGAAAGCGGTCTGGATTTTACCCT
GCAGAGCGTGGATCTGGCCCAAAAACGGCTGGAAAACGGGGAAGACTATCTGCTGATCAACCCGAAAGGTCAGGTGCCGG
CGCTGCTGCTGGATGATGATATCCTGCTCACTGAGGGCGTAGCCATCATGCAGTACATCGCAGACCAGGTGCCGGATCGT
CATCTGCTGGCGCCGGTGGGCTCGATTGCGCGCTATCAGACTCTCGAATGGCTGAACTATGTGGCCACCGAGCTGCATAA
AAGCTTTACCCCGCTGTTCCGCCCGGATACCCCGGAGGACTATAAGCCTGTCGCGCGGGGGCTGCTTGAGAAAAAGCTGC
AATACGTTGATGCAGCGCTGGCAGACAAACAGTGGCTGACCGGCCATCGCTTCACCATTGCCGATGGTTATCTGTTTACG
GTGCTGCGCTGGGCCTATGCTATAAAATTGGATATGGCTGCCTATGGTCATATCGGCAGCTGGATGACGCAGGTGGCAGC
GCGTCCGGCGGTGGCTGCCGCACTGGCGGCTGAAGGCTTAAAATAA

Upstream 100 bases:

>100_bases
AAAACTAATTATTTTTAAGCCGCTAACGTTAGTTTAGCGGCTTTTTTTTTACCCCTGGCAGGACTAACATACAGAAAACT
GCAGCCACGAGGAGTCACGC

Downstream 100 bases:

>100_bases
GGCCTGAACCTGCCCGGCGGACCGTCGGCAGGCCCTGGGAGTTACAGCCGGGTGGCGCTGAAGCAGTGCTCCGGTACGGC
GATGCGATCCTGCGCCGCTA

Product: glutathionine S-transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MKLFYKPGACSLASHIALRESGLDFTLQSVDLAQKRLENGEDYLLINPKGQVPALLLDDDILLTEGVAIMQYIADQVPDR
HLLAPVGSIARYQTLEWLNYVATELHKSFTPLFRPDTPEDYKPVARGLLEKKLQYVDAALADKQWLTGHRFTIADGYLFT
VLRWAYAIKLDMAAYGHIGSWMTQVAARPAVAAALAAEGLK

Sequences:

>Translated_201_residues
MKLFYKPGACSLASHIALRESGLDFTLQSVDLAQKRLENGEDYLLINPKGQVPALLLDDDILLTEGVAIMQYIADQVPDR
HLLAPVGSIARYQTLEWLNYVATELHKSFTPLFRPDTPEDYKPVARGLLEKKLQYVDAALADKQWLTGHRFTIADGYLFT
VLRWAYAIKLDMAAYGHIGSWMTQVAARPAVAAALAAEGLK
>Mature_201_residues
MKLFYKPGACSLASHIALRESGLDFTLQSVDLAQKRLENGEDYLLINPKGQVPALLLDDDILLTEGVAIMQYIADQVPDR
HLLAPVGSIARYQTLEWLNYVATELHKSFTPLFRPDTPEDYKPVARGLLEKKLQYVDAALADKQWLTGHRFTIADGYLFT
VLRWAYAIKLDMAAYGHIGSWMTQVAARPAVAAALAAEGLK

Specific function: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles [H]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787923, Length=201, Percent_Identity=74.1293532338308, Blast_Score=302, Evalue=1e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: =2.5.1.18 [H]

Molecular weight: Translated: 22375; Mature: 22375

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLFYKPGACSLASHIALRESGLDFTLQSVDLAQKRLENGEDYLLINPKGQVPALLLDDD
CCEEECCCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHCCCCCEEEECCCCCCCEEEECCC
ILLTEGVAIMQYIADQVPDRHLLAPVGSIARYQTLEWLNYVATELHKSFTPLFRPDTPED
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
YKPVARGLLEKKLQYVDAALADKQWLTGHRFTIADGYLFTVLRWAYAIKLDMAAYGHIGS
HHHHHHHHHHHHHHHHHHHHHCCHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
WMTQVAARPAVAAALAAEGLK
HHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKLFYKPGACSLASHIALRESGLDFTLQSVDLAQKRLENGEDYLLINPKGQVPALLLDDD
CCEEECCCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHCCCCCEEEECCCCCCCEEEECCC
ILLTEGVAIMQYIADQVPDRHLLAPVGSIARYQTLEWLNYVATELHKSFTPLFRPDTPED
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
YKPVARGLLEKKLQYVDAALADKQWLTGHRFTIADGYLFTVLRWAYAIKLDMAAYGHIGS
HHHHHHHHHHHHHHHHHHHHHCCHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
WMTQVAARPAVAAALAAEGLK
HHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]