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The map label for this gene is tppB [H]

Identifier: 152970524

GI number: 152970524

Start: 2168094

End: 2169566

Strand: Direct

Name: tppB [H]

Synonym: KPN_01972

Alternate gene names: 152970524

Gene position: 2168094-2169566 (Clockwise)

Preceding gene: 152970522

Following gene: 152970525

Centisome position: 40.79

GC content: 56.21

Gene sequence:

>1473_bases
GTGAGTCTGAACGCTTTCAAACAACCACGCGCGTTCTATCTCATTTTCTCGATCGAGTTGTGGGAGCGTTTTGGTTACTA
CGGCCTGCAAGGGATCATGGCCGTTTACCTGGTAAAACAGCTGGGTATGTCGGAAGCGGATTCCATTACTCTGTTCTCCT
CCTTTAGCGCGCTGGTTTATGGCCTCGTCGCCATTGGCGGCTGGCTGGGTGATAAAGTGCTGGGTACCAAGCGTGTCATC
ATGCTGGGCGCTATCGTGCTGGCGATTGGCTATGCGCTGGTGGCCTGGTCCGGTCATGACGCCGCTATCGTCTATATGGG
TATGGCGACCATCGCCGTCGGTAACGGCCTGTTTAAAGCCAACCCGTCCTCCCTGCTTTCTACCTGCTATGACAAAAACG
ACCCACGTCTGGACGGTGCATTTACCATGTACTACATGTCCATCAACATCGGTTCGTTCTTCTCTATGCTGGCAACCCCG
TGGCTGGCCGCACGTTTTGGCTGGAGCGTAGCGTTTGCCCTCAGCGTGGTGGGGATGGTGATCACCATTATTAACTTCGC
CTTCTGTCAGAAATGGGTTAAACAGTACGGCTCTAAACCGGACTTTGTCCCGGTACACATGGGTAAACTGCTGGCGACCA
TCGCTGGCGTGGTGGTGCTGGTCGCTATCGCCACCTGGCTGCTGCACAACCAGGGTATCGCACGTATGGTGCTGGGCGTC
GTCGCACTGGGTATCGTCGTGATTTTCGCCAAAGAAACCATAGGCCTGAAAGGCGCTCCGCGTCGTAAAATGATCGTCGC
TTTCCTGCTGATGGTAGAAGCGATTGTCTTCTTCGTGTTGTACAGCCAGATGCCGACCTCGCTGAACTTCTTCGCCATCC
GTAACGTGGAGCACTCGATCCTCGGTCTCGCCTTTGAACCGGAACAGTATCAGGCGCTGAACCCGTTCTGGATCATGATT
GGTAGCCCGATTCTGGCCGCCATCTACAACAAGATGGGCGACCGCCTGCCGATGCCGCACAAATTTGCTATCGGTATGGT
ACTGTGCTCTGGCGCATTCCTCGTCCTGCCTTTAGGGGCGAAGTTCGCCAGCGACGCCGGTATCGTCTCGGTCAACTGGC
TGATTCTGAGCTACGCGCTGCAGTCTATCGGTGAACTGATGATTTCCGGCCTCGGCCTGGCGATGGTCGCTCAGCTGGTT
CCTCAGCGTCTGATGGGCTTCATTATGGGCAGCTGGTTCCTCACCACGGCAGGCGCGGCGATCATCGCCGGGAAAATCGC
TAACCTGATGGCAGTCCCGGAGAATGTCACCGATCCGCTGGTGTCGCTGGAAGTGTACGGTCACGTATTCCTGCAGATTG
GTATCGTCACCGCGGTTATCGCCGCCCTGATGCTGCTGACCGCGCCGAAACTGAATCGTATGACTCAGGACGACAGCGCG
GACATTAAAGCACGCGAAACCGCGGCTGCCTGA

Upstream 100 bases:

>100_bases
GGCGGTCCAACGAGATTGCGCCCCGAACACCCCCCAGTAAATATGGGATGTAAAAAAAGAGGTATATGTGTCTACTGCAA
ACAATAAACCAGCAGAAAGC

Downstream 100 bases:

>100_bases
CGCCGCAGGGAAAACTAATTATTTTTAAGCCGCTAACGTTAGTTTAGCGGCTTTTTTTTTACCCCTGGCAGGACTAACAT
ACAGAAAACTGCAGCCACGA

Product: putative tripeptide transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 489

Protein sequence:

>490_residues
MSLNAFKQPRAFYLIFSIELWERFGYYGLQGIMAVYLVKQLGMSEADSITLFSSFSALVYGLVAIGGWLGDKVLGTKRVI
MLGAIVLAIGYALVAWSGHDAAIVYMGMATIAVGNGLFKANPSSLLSTCYDKNDPRLDGAFTMYYMSINIGSFFSMLATP
WLAARFGWSVAFALSVVGMVITIINFAFCQKWVKQYGSKPDFVPVHMGKLLATIAGVVVLVAIATWLLHNQGIARMVLGV
VALGIVVIFAKETIGLKGAPRRKMIVAFLLMVEAIVFFVLYSQMPTSLNFFAIRNVEHSILGLAFEPEQYQALNPFWIMI
GSPILAAIYNKMGDRLPMPHKFAIGMVLCSGAFLVLPLGAKFASDAGIVSVNWLILSYALQSIGELMISGLGLAMVAQLV
PQRLMGFIMGSWFLTTAGAAIIAGKIANLMAVPENVTDPLVSLEVYGHVFLQIGIVTAVIAALMLLTAPKLNRMTQDDSA
DIKARETAAA

Sequences:

>Translated_490_residues
MSLNAFKQPRAFYLIFSIELWERFGYYGLQGIMAVYLVKQLGMSEADSITLFSSFSALVYGLVAIGGWLGDKVLGTKRVI
MLGAIVLAIGYALVAWSGHDAAIVYMGMATIAVGNGLFKANPSSLLSTCYDKNDPRLDGAFTMYYMSINIGSFFSMLATP
WLAARFGWSVAFALSVVGMVITIINFAFCQKWVKQYGSKPDFVPVHMGKLLATIAGVVVLVAIATWLLHNQGIARMVLGV
VALGIVVIFAKETIGLKGAPRRKMIVAFLLMVEAIVFFVLYSQMPTSLNFFAIRNVEHSILGLAFEPEQYQALNPFWIMI
GSPILAAIYNKMGDRLPMPHKFAIGMVLCSGAFLVLPLGAKFASDAGIVSVNWLILSYALQSIGELMISGLGLAMVAQLV
PQRLMGFIMGSWFLTTAGAAIIAGKIANLMAVPENVTDPLVSLEVYGHVFLQIGIVTAVIAALMLLTAPKLNRMTQDDSA
DIKARETAAA
>Mature_489_residues
SLNAFKQPRAFYLIFSIELWERFGYYGLQGIMAVYLVKQLGMSEADSITLFSSFSALVYGLVAIGGWLGDKVLGTKRVIM
LGAIVLAIGYALVAWSGHDAAIVYMGMATIAVGNGLFKANPSSLLSTCYDKNDPRLDGAFTMYYMSINIGSFFSMLATPW
LAARFGWSVAFALSVVGMVITIINFAFCQKWVKQYGSKPDFVPVHMGKLLATIAGVVVLVAIATWLLHNQGIARMVLGVV
ALGIVVIFAKETIGLKGAPRRKMIVAFLLMVEAIVFFVLYSQMPTSLNFFAIRNVEHSILGLAFEPEQYQALNPFWIMIG
SPILAAIYNKMGDRLPMPHKFAIGMVLCSGAFLVLPLGAKFASDAGIVSVNWLILSYALQSIGELMISGLGLAMVAQLVP
QRLMGFIMGSWFLTTAGAAIIAGKIANLMAVPENVTDPLVSLEVYGHVFLQIGIVTAVIAALMLLTAPKLNRMTQDDSAD
IKARETAAA

Specific function: Proton-dependent permease that transports di- and tripeptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpA subfamily [H]

Homologues:

Organism=Homo sapiens, GI4827008, Length=381, Percent_Identity=24.6719160104987, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI226371746, Length=358, Percent_Identity=24.0223463687151, Blast_Score=72, Evalue=9e-13,
Organism=Escherichia coli, GI1787922, Length=476, Percent_Identity=87.3949579831933, Blast_Score=854, Evalue=0.0,
Organism=Escherichia coli, GI1789911, Length=472, Percent_Identity=52.5423728813559, Blast_Score=504, Evalue=1e-144,
Organism=Escherichia coli, GI1790572, Length=474, Percent_Identity=29.746835443038, Blast_Score=190, Evalue=1e-49,
Organism=Escherichia coli, GI1786927, Length=435, Percent_Identity=27.816091954023, Blast_Score=184, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17541704, Length=375, Percent_Identity=25.3333333333333, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71987453, Length=376, Percent_Identity=23.6702127659574, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17569141, Length=370, Percent_Identity=24.5945945945946, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24639585, Length=335, Percent_Identity=26.865671641791, Blast_Score=96, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24639581, Length=327, Percent_Identity=26.9113149847095, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24639583, Length=327, Percent_Identity=26.9113149847095, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28571098, Length=367, Percent_Identity=25.0681198910082, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28571102, Length=367, Percent_Identity=25.0681198910082, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28571100, Length=367, Percent_Identity=25.0681198910082, Blast_Score=85, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 53009; Mature: 52878

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: PS00778 HIS_ACID_PHOSPHAT_2 ; PS50850 MFS ; PS01022 PTR2_1 ; PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLNAFKQPRAFYLIFSIELWERFGYYGLQGIMAVYLVKQLGMSEADSITLFSSFSALVY
CCCCCCCCCCEEEEEEEHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
GLVAIGGWLGDKVLGTKRVIMLGAIVLAIGYALVAWSGHDAAIVYMGMATIAVGNGLFKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEHHHHHHHCCCCCCC
NPSSLLSTCYDKNDPRLDGAFTMYYMSINIGSFFSMLATPWLAARFGWSVAFALSVVGMV
CHHHHHHHHHCCCCCCCCCEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITIINFAFCQKWVKQYGSKPDFVPVHMGKLLATIAGVVVLVAIATWLLHNQGIARMVLGV
HHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
VALGIVVIFAKETIGLKGAPRRKMIVAFLLMVEAIVFFVLYSQMPTSLNFFAIRNVEHSI
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHH
LGLAFEPEQYQALNPFWIMIGSPILAAIYNKMGDRLPMPHKFAIGMVLCSGAFLVLPLGA
EEEEECCHHHCCCCCEEEEECCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEECCC
KFASDAGIVSVNWLILSYALQSIGELMISGLGLAMVAQLVPQRLMGFIMGSWFLTTAGAA
CCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
IIAGKIANLMAVPENVTDPLVSLEVYGHVFLQIGIVTAVIAALMLLTAPKLNRMTQDDSA
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCC
DIKARETAAA
CCCCHHHCCC
>Mature Secondary Structure 
SLNAFKQPRAFYLIFSIELWERFGYYGLQGIMAVYLVKQLGMSEADSITLFSSFSALVY
CCCCCCCCCEEEEEEEHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
GLVAIGGWLGDKVLGTKRVIMLGAIVLAIGYALVAWSGHDAAIVYMGMATIAVGNGLFKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEHHHHHHHCCCCCCC
NPSSLLSTCYDKNDPRLDGAFTMYYMSINIGSFFSMLATPWLAARFGWSVAFALSVVGMV
CHHHHHHHHHCCCCCCCCCEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITIINFAFCQKWVKQYGSKPDFVPVHMGKLLATIAGVVVLVAIATWLLHNQGIARMVLGV
HHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
VALGIVVIFAKETIGLKGAPRRKMIVAFLLMVEAIVFFVLYSQMPTSLNFFAIRNVEHSI
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHH
LGLAFEPEQYQALNPFWIMIGSPILAAIYNKMGDRLPMPHKFAIGMVLCSGAFLVLPLGA
EEEEECCHHHCCCCCEEEEECCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEECCC
KFASDAGIVSVNWLILSYALQSIGELMISGLGLAMVAQLVPQRLMGFIMGSWFLTTAGAA
CCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
IIAGKIANLMAVPENVTDPLVSLEVYGHVFLQIGIVTAVIAALMLLTAPKLNRMTQDDSA
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCC
DIKARETAAA
CCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA