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The map label for this gene is bioC [H]

Identifier: 152969359

GI number: 152969359

Start: 896142

End: 896897

Strand: Direct

Name: bioC [H]

Synonym: KPN_00802

Alternate gene names: 152969359

Gene position: 896142-896897 (Clockwise)

Preceding gene: 152969358

Following gene: 152969360

Centisome position: 16.86

GC content: 67.59

Gene sequence:

>756_bases
ATGGCCACAGTGAATAAGCAGGCGGTGGCCGCGGCGTTTGGCCGGGCGGCCAGCGGCTATACGCAACATGATGAACTGCA
GCGGCGCTGCGCCGATCTACTGCTGCGCCAGCTGGCGCGCCGCGATTTTGCGCAGGTGCTGGATGCCGGCTGCGGCCCCG
GCAGTATGAGTCGCTATTGGCGTGAGGCGGGCAGCGTGGTGACCGCGCTGGATCTCTCCGCCGGGATGCTCGCCCAGGCG
CAGCGTAACGACGCCGCGCAGCATTATCTGCTGGGGGATATTGAGGCGCTGCCGCTGCCGGACGCCTGCGTCGATCTGGC
GTGGAGCAATCTGGCGGTGCAGTGGTGCGACGATCTACGGGCGGCAATTGGCGAGCTGTACCGGGTGGCGCGTCCCGGCG
GCAGAGTGGCGTTTAGCACGCTGCTCGCCGACTCGCTGCCGGAGCTCAATCAGGCGTGGCAGGCCATCGACGACCGGCCG
CATGCCAACCGTTTCCTTAGCGAAGCGGCGGTGCGCGCGGCGCTTAGCGGCCTGCGCGCGACCGGCGAGGTTCATCAGAT
TAGCCTGCCGTTCGCCGATGCGCTGAGCGCTATGCGCTCGCTGAAGGGCATCGGCGCCACCCATTTGCACCAGGGGCGGA
CCGCCGCCCCGCTTGGCCGCGGCAAACTGCGCGAGCTGCAGCTGGCCTGGCCGCAGCGGCAGGGCATCTGCCCGCTGACG
TATTCTCTTTTTACAGGAGTCATTGAGCGTGACTAA

Upstream 100 bases:

>100_bases
ATCCGTCCACCGACGGTGCCGGTCGGCAGCGCGCGTTTGCGCCTGACCCTGACAGCCGCCCATCATACTGAAGACATTAA
CCGTTTACTGGAGGTGCTGC

Downstream 100 bases:

>100_bases
ACGTTTTTTTGTCACCGGGACCGATACTGAAGTCGGTAAAACCATCGCCAGCAGCGCCCTGCTGCAGGCGGCGAATCTGC
TGGGTTTTCACACTGCCGGC

Product: biotin biosynthesis protein BioC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MATVNKQAVAAAFGRAASGYTQHDELQRRCADLLLRQLARRDFAQVLDAGCGPGSMSRYWREAGSVVTALDLSAGMLAQA
QRNDAAQHYLLGDIEALPLPDACVDLAWSNLAVQWCDDLRAAIGELYRVARPGGRVAFSTLLADSLPELNQAWQAIDDRP
HANRFLSEAAVRAALSGLRATGEVHQISLPFADALSAMRSLKGIGATHLHQGRTAAPLGRGKLRELQLAWPQRQGICPLT
YSLFTGVIERD

Sequences:

>Translated_251_residues
MATVNKQAVAAAFGRAASGYTQHDELQRRCADLLLRQLARRDFAQVLDAGCGPGSMSRYWREAGSVVTALDLSAGMLAQA
QRNDAAQHYLLGDIEALPLPDACVDLAWSNLAVQWCDDLRAAIGELYRVARPGGRVAFSTLLADSLPELNQAWQAIDDRP
HANRFLSEAAVRAALSGLRATGEVHQISLPFADALSAMRSLKGIGATHLHQGRTAAPLGRGKLRELQLAWPQRQGICPLT
YSLFTGVIERD
>Mature_250_residues
ATVNKQAVAAAFGRAASGYTQHDELQRRCADLLLRQLARRDFAQVLDAGCGPGSMSRYWREAGSVVTALDLSAGMLAQAQ
RNDAAQHYLLGDIEALPLPDACVDLAWSNLAVQWCDDLRAAIGELYRVARPGGRVAFSTLLADSLPELNQAWQAIDDRPH
ANRFLSEAAVRAALSGLRATGEVHQISLPFADALSAMRSLKGIGATHLHQGRTAAPLGRGKLRELQLAWPQRQGICPLTY
SLFTGVIERD

Specific function: BioC is involved in an early, but chemically unexplored, step in the conversion of pimelic acid to biotin [H]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

Organism=Escherichia coli, GI1786994, Length=251, Percent_Identity=64.1434262948207, Blast_Score=301, Evalue=2e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011814
- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: NA

Molecular weight: Translated: 27168; Mature: 27037

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATVNKQAVAAAFGRAASGYTQHDELQRRCADLLLRQLARRDFAQVLDAGCGPGSMSRYW
CCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
REAGSVVTALDLSAGMLAQAQRNDAAQHYLLGDIEALPLPDACVDLAWSNLAVQWCDDLR
HHHCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AAIGELYRVARPGGRVAFSTLLADSLPELNQAWQAIDDRPHANRFLSEAAVRAALSGLRA
HHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHC
TGEVHQISLPFADALSAMRSLKGIGATHLHQGRTAAPLGRGKLRELQLAWPQRQGICPLT
CCCCEEEECCHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCCCHHH
YSLFTGVIERD
HHHHHHHHCCC
>Mature Secondary Structure 
ATVNKQAVAAAFGRAASGYTQHDELQRRCADLLLRQLARRDFAQVLDAGCGPGSMSRYW
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
REAGSVVTALDLSAGMLAQAQRNDAAQHYLLGDIEALPLPDACVDLAWSNLAVQWCDDLR
HHHCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AAIGELYRVARPGGRVAFSTLLADSLPELNQAWQAIDDRPHANRFLSEAAVRAALSGLRA
HHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHC
TGEVHQISLPFADALSAMRSLKGIGATHLHQGRTAAPLGRGKLRELQLAWPQRQGICPLT
CCCCEEEECCHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCCCHHH
YSLFTGVIERD
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3058702; 9278503 [H]