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The map label for this gene is glpC [C]

Identifier: 150401146

GI number: 150401146

Start: 736107

End: 737723

Strand: Direct

Name: glpC [C]

Synonym: Maeo_0717

Alternate gene names: 150401146

Gene position: 736107-737723 (Clockwise)

Preceding gene: 150401145

Following gene: 150401147

Centisome position: 46.9

GC content: 30.06

Gene sequence:

>1617_bases
ATGAAACAAATAAAATTAAAAATAAAATTAAATGGAGTATTTAAAGAATATTTCGTTCCAAATAATATAACTGTTTTAGA
AGCATTAGAATACATAAATAAAACATACAACGAAAATATACAATATAGGGCATCATGTAGGGCAGGACAGTGTGGAAGTT
GTGCCATGACGATAAATAACGAACCAAAACTTGCCTGTAAAACAAAAGTAGAGCATAACACAACAATAGAACCATTGAAA
AATTTCATTGTGATTAAAGATTTAATAGTAGATAGGGAACAATATTATAAAAAATTGAATAATATAAGAAATTATGTAGA
AAATGAAAAGGAAATTTTTTCTGGCGAAAATATTCAAAATAAAGAAGATACAATAAATGATTCGGAGAATACAGAAAATA
ATAAAATAGATACCTTAAAAGACAAAACAATAACAGCAATAAACAGCGCCGGGGACATAACCAATATAAAAAAAATAAGG
GGTTGCATAGATTGCCTGTCTTGTCTCTCAAAATGTCCAGCAAAGGAGTTTTCAGAATACCCTGGTCCAACTTTAATGAG
ACAGATTGCAAGATTTGCATTTGATAAAAGAGACAATATAAACAGGTGTGAAATGGCATTTTTTGAAAATTTACCAAATT
GCACAACCTGTGGAAAATGTGTTGAAGTGTGTCCAAAAGAAATTGACATAGTACATAATGCCGTGGAAAAATTAAGGGCA
AAAGCCTTTGAAAATGGATATTATTTAAAGGAGCATATGGAAGTTCGAAAAAATGTATTAAATAAAAATAATAACAACAG
GTCTATAATTAAAGAGAAAACTCCATTGTTGGAAGAAGTGCATAATGAGTATATTGTTGAACATGAAAAAATGAGGGTGG
CCTTTTTTACGGGCTGTTTGGTGGATTATAGACTTCAAGATGTGGGAAAAAGTGCTATAAAAATATTAAATGCTCATGGA
ATTTCTGTAATTATTCCAAAAAATCAAATTTGTTGCGGTTCTCCATTTATACGAACAGGTCAAACGGATGTGGCCAATAC
TTTAAAAAATCATAATTTAAATATATTTAACAATTTAGAAGTTGATGCCATAATTACTGTATGTGCGGGGTGCGGTAGCA
CACTTAAAAACGATTACAAAGAAAAAGAATTTAAAGTTATGGATATCACCGAAATATTAAACAAAGTGGGACTTATAAAC
TATAATCCACTTAAAGACCATACAAAATTAATAGGAATTCCAACAGAGGAACACGATAAAAAAATAAAAATAACATATCA
TGATCCATGTCATTTGAGAAGGGGACAAGGCATATTTGTTGAACCACGAAAAATATTAAGACATATTCCAAATTTGGAAT
TTATTGAGATGGAGCTCCCTGACCAATGTTGTGGTGCTGGTGGCGGTGTAAGAAGTGGAAAACCAGAATTAGCAAGTGCA
ATAGGAAAAAGAAAAGCTAAAATGATAGCAGATACAGATGCCGATTTTGTAATTACTGTATGTCCATTTTGCGAATACCA
TATAAAAGATAGCATAAATAAATACAATAAAGAAAATGATATTAAAAAAGATACTAAGGTATTAAATATAGTATCTCTAC
TTGATAAGGTGATTTAA

Upstream 100 bases:

>100_bases
TTAATTTTAATTTATTTAGGATTTATATTATTTATTTCCAATATATTATAAATAGATAGATATATAGATAAATAGATAAA
TAATAACACATCGTGATACA

Downstream 100 bases:

>100_bases
GTGGAAGATAATAATAATAATAATAATAATAATAATAATATAGATATATCCGAAATTATAAATAAATTAAAAAATAAAGA
AATAAAGCCATATCAATTAG

Product: succinate dehydrogenase/fumarate reductase iron-sulfur subunit

Products: fumarate; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 538; Mature: 538

Protein sequence:

>538_residues
MKQIKLKIKLNGVFKEYFVPNNITVLEALEYINKTYNENIQYRASCRAGQCGSCAMTINNEPKLACKTKVEHNTTIEPLK
NFIVIKDLIVDREQYYKKLNNIRNYVENEKEIFSGENIQNKEDTINDSENTENNKIDTLKDKTITAINSAGDITNIKKIR
GCIDCLSCLSKCPAKEFSEYPGPTLMRQIARFAFDKRDNINRCEMAFFENLPNCTTCGKCVEVCPKEIDIVHNAVEKLRA
KAFENGYYLKEHMEVRKNVLNKNNNNRSIIKEKTPLLEEVHNEYIVEHEKMRVAFFTGCLVDYRLQDVGKSAIKILNAHG
ISVIIPKNQICCGSPFIRTGQTDVANTLKNHNLNIFNNLEVDAIITVCAGCGSTLKNDYKEKEFKVMDITEILNKVGLIN
YNPLKDHTKLIGIPTEEHDKKIKITYHDPCHLRRGQGIFVEPRKILRHIPNLEFIEMELPDQCCGAGGGVRSGKPELASA
IGKRKAKMIADTDADFVITVCPFCEYHIKDSINKYNKENDIKKDTKVLNIVSLLDKVI

Sequences:

>Translated_538_residues
MKQIKLKIKLNGVFKEYFVPNNITVLEALEYINKTYNENIQYRASCRAGQCGSCAMTINNEPKLACKTKVEHNTTIEPLK
NFIVIKDLIVDREQYYKKLNNIRNYVENEKEIFSGENIQNKEDTINDSENTENNKIDTLKDKTITAINSAGDITNIKKIR
GCIDCLSCLSKCPAKEFSEYPGPTLMRQIARFAFDKRDNINRCEMAFFENLPNCTTCGKCVEVCPKEIDIVHNAVEKLRA
KAFENGYYLKEHMEVRKNVLNKNNNNRSIIKEKTPLLEEVHNEYIVEHEKMRVAFFTGCLVDYRLQDVGKSAIKILNAHG
ISVIIPKNQICCGSPFIRTGQTDVANTLKNHNLNIFNNLEVDAIITVCAGCGSTLKNDYKEKEFKVMDITEILNKVGLIN
YNPLKDHTKLIGIPTEEHDKKIKITYHDPCHLRRGQGIFVEPRKILRHIPNLEFIEMELPDQCCGAGGGVRSGKPELASA
IGKRKAKMIADTDADFVITVCPFCEYHIKDSINKYNKENDIKKDTKVLNIVSLLDKVI
>Mature_538_residues
MKQIKLKIKLNGVFKEYFVPNNITVLEALEYINKTYNENIQYRASCRAGQCGSCAMTINNEPKLACKTKVEHNTTIEPLK
NFIVIKDLIVDREQYYKKLNNIRNYVENEKEIFSGENIQNKEDTINDSENTENNKIDTLKDKTITAINSAGDITNIKKIR
GCIDCLSCLSKCPAKEFSEYPGPTLMRQIARFAFDKRDNINRCEMAFFENLPNCTTCGKCVEVCPKEIDIVHNAVEKLRA
KAFENGYYLKEHMEVRKNVLNKNNNNRSIIKEKTPLLEEVHNEYIVEHEKMRVAFFTGCLVDYRLQDVGKSAIKILNAHG
ISVIIPKNQICCGSPFIRTGQTDVANTLKNHNLNIFNNLEVDAIITVCAGCGSTLKNDYKEKEFKVMDITEILNKVGLIN
YNPLKDHTKLIGIPTEEHDKKIKITYHDPCHLRRGQGIFVEPRKILRHIPNLEFIEMELPDQCCGAGGGVRSGKPELASA
IGKRKAKMIADTDADFVITVCPFCEYHIKDSINKYNKENDIKKDTKVLNIVSLLDKVI

Specific function: Electron Transfer Protein; May Also Function As The Membrane Anchor For The Glpab Dimer. [C]

COG id: COG0247

COG function: function code C; Fe-S oxidoreductase

Gene ontology:

Cell location: Loosely Bound To The Cytoplasm Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=214, Percent_Identity=30.3738317757009, Blast_Score=93, Evalue=7e-19,
Organism=Escherichia coli, GI1788576, Length=397, Percent_Identity=25.4408060453401, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1790596, Length=223, Percent_Identity=31.8385650224215, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1786943, Length=221, Percent_Identity=27.6018099547511, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1786497, Length=253, Percent_Identity=24.1106719367589, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17533915, Length=216, Percent_Identity=26.8518518518519, Blast_Score=89, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6322987, Length=229, Percent_Identity=28.82096069869, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24643156, Length=224, Percent_Identity=25.8928571428571, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17137106, Length=216, Percent_Identity=27.7777777777778, Blast_Score=88, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR004017
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: PF02754 CCG; PF00111 Fer2 [H]

EC number: 1.3.99.1

Molecular weight: Translated: 61313; Mature: 61313

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQIKLKIKLNGVFKEYFVPNNITVLEALEYINKTYNENIQYRASCRAGQCGSCAMTINN
CCEEEEEEEEECEEHHHCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEECC
EPKLACKTKVEHNTTIEPLKNFIVIKDLIVDREQYYKKLNNIRNYVENEKEIFSGENIQN
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCC
KEDTINDSENTENNKIDTLKDKTITAINSAGDITNIKKIRGCIDCLSCLSKCPAKEFSEY
CCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHCC
PGPTLMRQIARFAFDKRDNINRCEMAFFENLPNCTTCGKCVEVCPKEIDIVHNAVEKLRA
CCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHH
KAFENGYYLKEHMEVRKNVLNKNNNNRSIIKEKTPLLEEVHNEYIVEHEKMRVAFFTGCL
HHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHEEEEHHHHHH
VDYRLQDVGKSAIKILNAHGISVIIPKNQICCGSPFIRTGQTDVANTLKNHNLNIFNNLE
HHHHHHHHCHHHHHHHHCCCEEEEECCCCEECCCCCCCCCCHHHHHHHHCCCCCEECCCC
VDAIITVCAGCGSTLKNDYKEKEFKVMDITEILNKVGLINYNPLKDHTKLIGIPTEEHDK
HHHHHHHHHCCCHHHHHHHHHHHEEEEEHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCC
KIKITYHDPCHLRRGQGIFVEPRKILRHIPNLEFIEMELPDQCCGAGGGVRSGKPELASA
EEEEEECCCCCCCCCCCEEECHHHHHHHCCCCEEEEEECCHHHHCCCCCCCCCCHHHHHH
IGKRKAKMIADTDADFVITVCPFCEYHIKDSINKYNKENDIKKDTKVLNIVSLLDKVI
HHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MKQIKLKIKLNGVFKEYFVPNNITVLEALEYINKTYNENIQYRASCRAGQCGSCAMTINN
CCEEEEEEEEECEEHHHCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEECC
EPKLACKTKVEHNTTIEPLKNFIVIKDLIVDREQYYKKLNNIRNYVENEKEIFSGENIQN
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCC
KEDTINDSENTENNKIDTLKDKTITAINSAGDITNIKKIRGCIDCLSCLSKCPAKEFSEY
CCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHCC
PGPTLMRQIARFAFDKRDNINRCEMAFFENLPNCTTCGKCVEVCPKEIDIVHNAVEKLRA
CCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHH
KAFENGYYLKEHMEVRKNVLNKNNNNRSIIKEKTPLLEEVHNEYIVEHEKMRVAFFTGCL
HHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHEEEEHHHHHH
VDYRLQDVGKSAIKILNAHGISVIIPKNQICCGSPFIRTGQTDVANTLKNHNLNIFNNLE
HHHHHHHHCHHHHHHHHCCCEEEEECCCCEECCCCCCCCCCHHHHHHHHCCCCCEECCCC
VDAIITVCAGCGSTLKNDYKEKEFKVMDITEILNKVGLINYNPLKDHTKLIGIPTEEHDK
HHHHHHHHHCCCHHHHHHHHHHHEEEEEHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCC
KIKITYHDPCHLRRGQGIFVEPRKILRHIPNLEFIEMELPDQCCGAGGGVRSGKPELASA
EEEEEECCCCCCCCCCCEEECHHHHHHHCCCCEEEEEECCHHHHCCCCCCCCCCHHHHHH
IGKRKAKMIADTDADFVITVCPFCEYHIKDSINKYNKENDIKKDTKVLNIVSLLDKVI
HHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: succinate; acceptor

Specific reaction: succinate + acceptor = fumarate + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA