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The map label for this gene is ycgO [C]

Identifier: 150400915

GI number: 150400915

Start: 505625

End: 506884

Strand: Direct

Name: ycgO [C]

Synonym: Maeo_0483

Alternate gene names: 150400915

Gene position: 505625-506884 (Clockwise)

Preceding gene: 150400907

Following gene: 150400916

Centisome position: 32.22

GC content: 34.05

Gene sequence:

>1260_bases
ATGGATTTAGCCATTGCCATAGGGTATTTAGCACTGTTGTTTATTTCTGGTTCAATTATCGCTAAAATCGGAGAGAAATT
AAAACTTCCAGATATACCATTATTGTTAATATTTGGGTTAATAGCGGGACCTTTTTTAGGCATAATATCCACAGCAGACG
CCCAAAATATATTTGAATATGTAGCAAATATTGGATTAATAGTATTGTTATTAGGTGGGGCTCTTGACATGAGGTGGATT
GTCTTAAAGAGAGTGTTAAACACAGTTTTAAAGTTAGATGTTATTGGATTAATCGGTGTTTTTGGAATTTCAGGATTATT
ATTTAATTTTATTTTTAAAATACCATTATTTAGTCCAATTGGTTATTTATATGGTGCTATTGTATGTGCCACCGACCCAG
CTACACTTATGCCAGTATTTTCAAAATCAAAAATTGACCCAAAAATAGCTTTAACTCTTGAAGCAGAAAGTGTATTTAAT
GACCCATTGGGTATTGTAGTTACAACTATAATGTTATCTACGCTAGGTCTTGCAGAGAATTTAAACCCTATTTTGAATTT
CATAACTCTTGCAATCGGTGGAGTAGTATTGGGGATAATAGGGGGGAAAATATTTGAAAAAACAGTATTAAAATGTGATT
TTAAAGAGTTTGTAGCTCCATTAGGTATTGGGTTATCATTATTGTTGTGGTATTTTGGTGAAGAGCTATTTCCATTATTG
TCCTCAGGATACGAAATTAGCGGTTTTATGGCTGTTGCAATAATGGGATTATATTTGGGAAATACACTCACAAAATATGA
AAAACAGTCAAAATATATTGAGGAAATTGATGAATTTTGTAGTATGTTATCTACTTTATTTAGGGTATTGATATTTGTAT
TTTTAGGTGCAAGTATAAGTTTATCGGTATTATCTGAATACTGGATTTTAGGATTATTATGTGCGTTGGGCTCAATATTC
ATTGGAAGACCATTGGGAGTATTTGCTGCTACCTCAATACCGCCTGCAAGTGATATTAAAGAAAGAATATATTATTCATT
GGAAGGTCCAAGGGGCGTAGTTCCTGCGGCACTATCTGCCACCATCTATTCTTTAATAATGACTCACCCCGATGCAATTC
CTAGTGCCATCACAGCATACATAGCCCCAGATGCAATAGCTGGTTCAATACTTGTTGCTACCTTTATGACAATACTGTTA
AGTGTGGTTTTAGAGGCATCGTGGGCGGAGCTCCTGGGAAAAAAACTATTCAAATATTAA

Upstream 100 bases:

>100_bases
TTATACAATATCTAAACCATTTAAAATGGACATAATATTTAGTTAAGCAATGATAATAATATACAAATAATATACAAATT
ATTTTTATGAAGGTGTTTTA

Downstream 100 bases:

>100_bases
ATACATTAAATAATTTATTTTTTTTATCTTTATTTTTATTTTTATTTTTTTATTACATACATCGGTGATTAAATGAAGTT
GGACAAATCAAAGCAAAAGG

Product: sodium/hydrogen exchanger

Products: NA

Alternate protein names: MjNhaP2 [H]

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MDLAIAIGYLALLFISGSIIAKIGEKLKLPDIPLLLIFGLIAGPFLGIISTADAQNIFEYVANIGLIVLLLGGALDMRWI
VLKRVLNTVLKLDVIGLIGVFGISGLLFNFIFKIPLFSPIGYLYGAIVCATDPATLMPVFSKSKIDPKIALTLEAESVFN
DPLGIVVTTIMLSTLGLAENLNPILNFITLAIGGVVLGIIGGKIFEKTVLKCDFKEFVAPLGIGLSLLLWYFGEELFPLL
SSGYEISGFMAVAIMGLYLGNTLTKYEKQSKYIEEIDEFCSMLSTLFRVLIFVFLGASISLSVLSEYWILGLLCALGSIF
IGRPLGVFAATSIPPASDIKERIYYSLEGPRGVVPAALSATIYSLIMTHPDAIPSAITAYIAPDAIAGSILVATFMTILL
SVVLEASWAELLGKKLFKY

Sequences:

>Translated_419_residues
MDLAIAIGYLALLFISGSIIAKIGEKLKLPDIPLLLIFGLIAGPFLGIISTADAQNIFEYVANIGLIVLLLGGALDMRWI
VLKRVLNTVLKLDVIGLIGVFGISGLLFNFIFKIPLFSPIGYLYGAIVCATDPATLMPVFSKSKIDPKIALTLEAESVFN
DPLGIVVTTIMLSTLGLAENLNPILNFITLAIGGVVLGIIGGKIFEKTVLKCDFKEFVAPLGIGLSLLLWYFGEELFPLL
SSGYEISGFMAVAIMGLYLGNTLTKYEKQSKYIEEIDEFCSMLSTLFRVLIFVFLGASISLSVLSEYWILGLLCALGSIF
IGRPLGVFAATSIPPASDIKERIYYSLEGPRGVVPAALSATIYSLIMTHPDAIPSAITAYIAPDAIAGSILVATFMTILL
SVVLEASWAELLGKKLFKY
>Mature_419_residues
MDLAIAIGYLALLFISGSIIAKIGEKLKLPDIPLLLIFGLIAGPFLGIISTADAQNIFEYVANIGLIVLLLGGALDMRWI
VLKRVLNTVLKLDVIGLIGVFGISGLLFNFIFKIPLFSPIGYLYGAIVCATDPATLMPVFSKSKIDPKIALTLEAESVFN
DPLGIVVTTIMLSTLGLAENLNPILNFITLAIGGVVLGIIGGKIFEKTVLKCDFKEFVAPLGIGLSLLLWYFGEELFPLL
SSGYEISGFMAVAIMGLYLGNTLTKYEKQSKYIEEIDEFCSMLSTLFRVLIFVFLGASISLSVLSEYWILGLLCALGSIF
IGRPLGVFAATSIPPASDIKERIYYSLEGPRGVVPAALSATIYSLIMTHPDAIPSAITAYIAPDAIAGSILVATFMTILL
SVVLEASWAELLGKKLFKY

Specific function: This is probably a Na(+)/H(+) antiporter [H]

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family [H]

Homologues:

Organism=Homo sapiens, GI15529998, Length=356, Percent_Identity=26.685393258427, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI87081854, Length=335, Percent_Identity=26.865671641791, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI221510740, Length=299, Percent_Identity=23.7458193979933, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24585580, Length=299, Percent_Identity=23.7458193979933, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24585578, Length=299, Percent_Identity=23.7458193979933, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 45087; Mature: 45087

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLAIAIGYLALLFISGSIIAKIGEKLKLPDIPLLLIFGLIAGPFLGIISTADAQNIFEY
CCHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHH
VANIGLIVLLLGGALDMRWIVLKRVLNTVLKLDVIGLIGVFGISGLLFNFIFKIPLFSPI
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GYLYGAIVCATDPATLMPVFSKSKIDPKIALTLEAESVFNDPLGIVVTTIMLSTLGLAEN
HHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEEEEHHHHHCCCHHHHHHHHHHHHHHHHHH
LNPILNFITLAIGGVVLGIIGGKIFEKTVLKCDFKEFVAPLGIGLSLLLWYFGEELFPLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSGYEISGFMAVAIMGLYLGNTLTKYEKQSKYIEEIDEFCSMLSTLFRVLIFVFLGASIS
HCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LSVLSEYWILGLLCALGSIFIGRPLGVFAATSIPPASDIKERIYYSLEGPRGVVPAALSA
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHEECCCCCCCHHHHHHH
TIYSLIMTHPDAIPSAITAYIAPDAIAGSILVATFMTILLSVVLEASWAELLGKKLFKY
HHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDLAIAIGYLALLFISGSIIAKIGEKLKLPDIPLLLIFGLIAGPFLGIISTADAQNIFEY
CCHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHH
VANIGLIVLLLGGALDMRWIVLKRVLNTVLKLDVIGLIGVFGISGLLFNFIFKIPLFSPI
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GYLYGAIVCATDPATLMPVFSKSKIDPKIALTLEAESVFNDPLGIVVTTIMLSTLGLAEN
HHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEEEEHHHHHCCCHHHHHHHHHHHHHHHHHH
LNPILNFITLAIGGVVLGIIGGKIFEKTVLKCDFKEFVAPLGIGLSLLLWYFGEELFPLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSGYEISGFMAVAIMGLYLGNTLTKYEKQSKYIEEIDEFCSMLSTLFRVLIFVFLGASIS
HCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LSVLSEYWILGLLCALGSIFIGRPLGVFAATSIPPASDIKERIYYSLEGPRGVVPAALSA
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHEECCCCCCCHHHHHHH
TIYSLIMTHPDAIPSAITAYIAPDAIAGSILVATFMTILLSVVLEASWAELLGKKLFKY
HHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]