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The map label for this gene is 150400487

Identifier: 150400487

GI number: 150400487

Start: 55173

End: 57080

Strand: Reverse

Name: 150400487

Synonym: Maeo_0049

Alternate gene names: NA

Gene position: 57080-55173 (Counterclockwise)

Preceding gene: 150400488

Following gene: 150400485

Centisome position: 3.64

GC content: 33.81

Gene sequence:

>1908_bases
TTGTCAGCCGAAGATATTTTAAATGAAATAAAAAATCATGTAATGAAAACAGCACCAGGAAATGCTGCAATTACAGATGT
GCAATTTGAAGGACCCGAAGTAGTAATATATGCCAAAAATCCAGAGATTTTTTCCAACACATTTGTAAGAGAATTGGCAA
AATTATTTAGAAAAAGGATAGCCATAAGACCAGACCCTTCTGTTTTAATGGAGCCAGAAATAGCAAAAAAGAAAATTTTA
GAAATTATACCTGATGATGCCGAAATTACAAACTGCATATTTGATGCAAATACTGGAGAAATAATTATAGAATCAAAAAA
ACCAGGGTTGGTAATCGGAAAAGAAGGTAGCACATTAGAAGAATTGAAAAAAGAAATAAAATGGGCACCTAAGCCAGTTC
GAACCCCTCCAATTTCATCCGAAACTGTTAATGCCATAAGGGCAACATTATACAGGGAACGAATGGATGTAAAAGAAATT
CTTAGGAGAGTTGGAAAGGTAATACATAGAGATGTTAAATTAAGAGAAGATTCATGGATAAGAATGTCTTTTTTAGGTGG
GGCTCGAGAAGTAGGTAGAACTTGTAATTATCTACAAACCCCTGAAAGTAGAATATTAATTGATTGCGGTATAAATGTGG
CAATGGATGGAGACAGAGCTTTTCCACATTTCGATGCTCCTGAATTTGCAGTTGAAGAAATTGATGCCGTAGTAGTTACT
CACGCTCATTTAGACCATTGCGGTTTTGTCCCGGGGCTTTTTAGGTATGGATATGATGGTCCAATTTATTGTTCCAAACC
AACCAGAGATTTAATGACTCTTTTACAAAAAGATTATATTGATATTGCTGAAAAAGAAGGAAAAGTTGTTCCATATTCTT
CAAAAGATATTAAAAAATGTGTTAAACATATTATTCCTATTGATTATGGAGTAACAACCGATGTTGCACCTGCCATAAAA
TTAACCATGCATAATGCAGGGCATATACTTGGTTCAGCAATAGCTCACTGCCATATCGGAGATGGATTATATAATATAGC
ATATACAGGAGACATAAAATTTGAAGCCTCCCGATTATTGGAACCGGCCGTATGCAATTTCCCAAGATTAGAAACTTTAA
TTATAGAATCTACCTATGGGGCTTATGATGATGTTTTACCGGATAAAGGAGAAACAGAACAGAACTTTTTAAAAGTAATT
GCTGAAACAATTAAAAGAAAAGGAAAAATTATAATTCCTGTATTTGGAATTGGTAGGGCACAGGAATTAATGTTGGTATT
AGAAGAAGGATATAATCAAGGCATATTTAATGCCCCTGTTTATTTAGATGGTATGATTTGGGAAGCTACGGCAATACATA
CAGCATATCCTGAATATTTATCAAAAAATATGAGAAATAGGATATTCCACGAAGGAGATAATCCATTCCTTTCGGAAGTA
TTTAAAAAAGTAAGAAATACCAACAATAGACGAAACATAATTGATAGCGATGAGCCCTGTATTATATTGACCACATCTGG
AATGCTTAGCGGCGGTCCAAGTGTAGAATACTTTAAATCATTGGCTCATGATGAAAGAAACGCAATTGTATTTGTTGGTT
ATCAATCAGAAGGAACTATGGGAAGAAAAATCCAAAGAGGCTGGAATGAAATCCCAGTAATGAATAGAAATGGAAAATCA
AGAGCTGTAAAAGTAAATTTAAGTGTTCATACATTTGAAGGATTTTCAGGACATAGCGATAGAAGACAGCTTATAAAATA
TTTAAGAAAGTTAAAACCTATGCCCGATAGAATATTAACAGTTCATGGGGAATCCTCTAAATGTATAGATTTAGCTAGTG
CCGCATATAAATTATTTAAAAAAGAAACAAGAGCTCCGATGAATTTAGATGCCGTTAGATTAAAATAA

Upstream 100 bases:

>100_bases
CTATTATTTTACAATTTAACCTATATTTTATACCACATATATCAACATATATATTTTATATCAAGATTATAATTTAATAA
ATTTAATAGAGGAGTTTATT

Downstream 100 bases:

>100_bases
AAAATATGAATATATGCTTTGGAGCTCCCATATTTTGCAATACAAAATCCAAATGATTTTGTTCAAAAGCAGAGCTTTTG
AATACTAAAAATAAAAATAT

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 635; Mature: 634

Protein sequence:

>635_residues
MSAEDILNEIKNHVMKTAPGNAAITDVQFEGPEVVIYAKNPEIFSNTFVRELAKLFRKRIAIRPDPSVLMEPEIAKKKIL
EIIPDDAEITNCIFDANTGEIIIESKKPGLVIGKEGSTLEELKKEIKWAPKPVRTPPISSETVNAIRATLYRERMDVKEI
LRRVGKVIHRDVKLREDSWIRMSFLGGAREVGRTCNYLQTPESRILIDCGINVAMDGDRAFPHFDAPEFAVEEIDAVVVT
HAHLDHCGFVPGLFRYGYDGPIYCSKPTRDLMTLLQKDYIDIAEKEGKVVPYSSKDIKKCVKHIIPIDYGVTTDVAPAIK
LTMHNAGHILGSAIAHCHIGDGLYNIAYTGDIKFEASRLLEPAVCNFPRLETLIIESTYGAYDDVLPDKGETEQNFLKVI
AETIKRKGKIIIPVFGIGRAQELMLVLEEGYNQGIFNAPVYLDGMIWEATAIHTAYPEYLSKNMRNRIFHEGDNPFLSEV
FKKVRNTNNRRNIIDSDEPCIILTTSGMLSGGPSVEYFKSLAHDERNAIVFVGYQSEGTMGRKIQRGWNEIPVMNRNGKS
RAVKVNLSVHTFEGFSGHSDRRQLIKYLRKLKPMPDRILTVHGESSKCIDLASAAYKLFKKETRAPMNLDAVRLK

Sequences:

>Translated_635_residues
MSAEDILNEIKNHVMKTAPGNAAITDVQFEGPEVVIYAKNPEIFSNTFVRELAKLFRKRIAIRPDPSVLMEPEIAKKKIL
EIIPDDAEITNCIFDANTGEIIIESKKPGLVIGKEGSTLEELKKEIKWAPKPVRTPPISSETVNAIRATLYRERMDVKEI
LRRVGKVIHRDVKLREDSWIRMSFLGGAREVGRTCNYLQTPESRILIDCGINVAMDGDRAFPHFDAPEFAVEEIDAVVVT
HAHLDHCGFVPGLFRYGYDGPIYCSKPTRDLMTLLQKDYIDIAEKEGKVVPYSSKDIKKCVKHIIPIDYGVTTDVAPAIK
LTMHNAGHILGSAIAHCHIGDGLYNIAYTGDIKFEASRLLEPAVCNFPRLETLIIESTYGAYDDVLPDKGETEQNFLKVI
AETIKRKGKIIIPVFGIGRAQELMLVLEEGYNQGIFNAPVYLDGMIWEATAIHTAYPEYLSKNMRNRIFHEGDNPFLSEV
FKKVRNTNNRRNIIDSDEPCIILTTSGMLSGGPSVEYFKSLAHDERNAIVFVGYQSEGTMGRKIQRGWNEIPVMNRNGKS
RAVKVNLSVHTFEGFSGHSDRRQLIKYLRKLKPMPDRILTVHGESSKCIDLASAAYKLFKKETRAPMNLDAVRLK
>Mature_634_residues
SAEDILNEIKNHVMKTAPGNAAITDVQFEGPEVVIYAKNPEIFSNTFVRELAKLFRKRIAIRPDPSVLMEPEIAKKKILE
IIPDDAEITNCIFDANTGEIIIESKKPGLVIGKEGSTLEELKKEIKWAPKPVRTPPISSETVNAIRATLYRERMDVKEIL
RRVGKVIHRDVKLREDSWIRMSFLGGAREVGRTCNYLQTPESRILIDCGINVAMDGDRAFPHFDAPEFAVEEIDAVVVTH
AHLDHCGFVPGLFRYGYDGPIYCSKPTRDLMTLLQKDYIDIAEKEGKVVPYSSKDIKKCVKHIIPIDYGVTTDVAPAIKL
TMHNAGHILGSAIAHCHIGDGLYNIAYTGDIKFEASRLLEPAVCNFPRLETLIIESTYGAYDDVLPDKGETEQNFLKVIA
ETIKRKGKIIIPVFGIGRAQELMLVLEEGYNQGIFNAPVYLDGMIWEATAIHTAYPEYLSKNMRNRIFHEGDNPFLSEVF
KKVRNTNNRRNIIDSDEPCIILTTSGMLSGGPSVEYFKSLAHDERNAIVFVGYQSEGTMGRKIQRGWNEIPVMNRNGKSR
AVKVNLSVHTFEGFSGHSDRRQLIKYLRKLKPMPDRILTVHGESSKCIDLASAAYKLFKKETRAPMNLDAVRLK

Specific function: Unknown

COG id: COG1782

COG function: function code R; Predicted metal-dependent RNase, consists of a metallo-beta-lactamase domain and an RNA-binding KH domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI33300633, Length=461, Percent_Identity=30.58568329718, Blast_Score=227, Evalue=2e-59,
Organism=Homo sapiens, GI7706427, Length=460, Percent_Identity=30.8695652173913, Blast_Score=215, Evalue=9e-56,
Organism=Homo sapiens, GI34101288, Length=375, Percent_Identity=22.4, Blast_Score=91, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI32564696, Length=460, Percent_Identity=30.2173913043478, Blast_Score=214, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI32566029, Length=463, Percent_Identity=30.8855291576674, Blast_Score=196, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI17559452, Length=383, Percent_Identity=22.976501305483, Blast_Score=86, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6323307, Length=454, Percent_Identity=28.8546255506608, Blast_Score=184, Evalue=4e-47,
Organism=Drosophila melanogaster, GI21358523, Length=455, Percent_Identity=31.4285714285714, Blast_Score=226, Evalue=4e-59,
Organism=Drosophila melanogaster, GI24648013, Length=469, Percent_Identity=29.2110874200426, Blast_Score=209, Evalue=3e-54,
Organism=Drosophila melanogaster, GI21358013, Length=378, Percent_Identity=23.2804232804233, Blast_Score=91, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022712
- InterPro:   IPR001279
- InterPro:   IPR004087
- InterPro:   IPR019975
- InterPro:   IPR004044
- InterPro:   IPR011108 [H]

Pfam domain/function: PF10996 Beta-Casp; PF07650 KH_2; PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 71461; Mature: 71330

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: PS50084 KH_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAEDILNEIKNHVMKTAPGNAAITDVQFEGPEVVIYAKNPEIFSNTFVRELAKLFRKRI
CCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHC
AIRPDPSVLMEPEIAKKKILEIIPDDAEITNCIFDANTGEIIIESKKPGLVIGKEGSTLE
CCCCCCCCEECCHHHHHHHHHHCCCCHHHHHEEEECCCCCEEEECCCCCEEEECCCCHHH
ELKKEIKWAPKPVRTPPISSETVNAIRATLYRERMDVKEILRRVGKVIHRDVKLREDSWI
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCEECCCCEE
RMSFLGGAREVGRTCNYLQTPESRILIDCGINVAMDGDRAFPHFDAPEFAVEEIDAVVVT
EEEECCCHHHHHHCCCCCCCCCCCEEEEECCEEEECCCCCCCCCCCCHHHHHHHCEEEEE
HAHLDHCGFVPGLFRYGYDGPIYCSKPTRDLMTLLQKDYIDIAEKEGKVVPYSSKDIKKC
EHHHHHCCCHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
VKHIIPIDYGVTTDVAPAIKLTMHNAGHILGSAIAHCHIGDGLYNIAYTGDIKFEASRLL
HHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHEEECCCEEEEEEECCEEECHHHCC
EPAVCNFPRLETLIIESTYGAYDDVLPDKGETEQNFLKVIAETIKRKGKIIIPVFGIGRA
CHHHCCCCCCEEEEEECCCCCHHCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCH
QELMLVLEEGYNQGIFNAPVYLDGMIWEATAIHTAYPEYLSKNMRNRIFHEGDNPFLSEV
HHHHHHHHCCCCCCCCCCCEEECCEEEEHHHHHHHCHHHHHHHHHHHHEECCCCHHHHHH
FKKVRNTNNRRNIIDSDEPCIILTTSGMLSGGPSVEYFKSLAHDERNAIVFVGYQSEGTM
HHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCEEEEEEECCCCCC
GRKIQRGWNEIPVMNRNGKSRAVKVNLSVHTFEGFSGHSDRRQLIKYLRKLKPMPDRILT
HHHHHCCCCCCCCCCCCCCCEEEEEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCEEE
VHGESSKCIDLASAAYKLFKKETRAPMNLDAVRLK
EECCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEC
>Mature Secondary Structure 
SAEDILNEIKNHVMKTAPGNAAITDVQFEGPEVVIYAKNPEIFSNTFVRELAKLFRKRI
CHHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHC
AIRPDPSVLMEPEIAKKKILEIIPDDAEITNCIFDANTGEIIIESKKPGLVIGKEGSTLE
CCCCCCCCEECCHHHHHHHHHHCCCCHHHHHEEEECCCCCEEEECCCCCEEEECCCCHHH
ELKKEIKWAPKPVRTPPISSETVNAIRATLYRERMDVKEILRRVGKVIHRDVKLREDSWI
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCEECCCCEE
RMSFLGGAREVGRTCNYLQTPESRILIDCGINVAMDGDRAFPHFDAPEFAVEEIDAVVVT
EEEECCCHHHHHHCCCCCCCCCCCEEEEECCEEEECCCCCCCCCCCCHHHHHHHCEEEEE
HAHLDHCGFVPGLFRYGYDGPIYCSKPTRDLMTLLQKDYIDIAEKEGKVVPYSSKDIKKC
EHHHHHCCCHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
VKHIIPIDYGVTTDVAPAIKLTMHNAGHILGSAIAHCHIGDGLYNIAYTGDIKFEASRLL
HHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHEEECCCEEEEEEECCEEECHHHCC
EPAVCNFPRLETLIIESTYGAYDDVLPDKGETEQNFLKVIAETIKRKGKIIIPVFGIGRA
CHHHCCCCCCEEEEEECCCCCHHCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCH
QELMLVLEEGYNQGIFNAPVYLDGMIWEATAIHTAYPEYLSKNMRNRIFHEGDNPFLSEV
HHHHHHHHCCCCCCCCCCCEEECCEEEEHHHHHHHCHHHHHHHHHHHHEECCCCHHHHHH
FKKVRNTNNRRNIIDSDEPCIILTTSGMLSGGPSVEYFKSLAHDERNAIVFVGYQSEGTM
HHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCEEEEEEECCCCCC
GRKIQRGWNEIPVMNRNGKSRAVKVNLSVHTFEGFSGHSDRRQLIKYLRKLKPMPDRILT
HHHHHCCCCCCCCCCCCCCCEEEEEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCEEE
VHGESSKCIDLASAAYKLFKKETRAPMNLDAVRLK
EECCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]