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The map label for this gene is tlpC [H]

Identifier: 150399841

GI number: 150399841

Start: 1109078

End: 1111270

Strand: Reverse

Name: tlpC [H]

Synonym: Mevan_1096

Alternate gene names: 150399841

Gene position: 1111270-1109078 (Counterclockwise)

Preceding gene: 150399842

Following gene: 150399834

Centisome position: 64.61

GC content: 30.83

Gene sequence:

>2193_bases
ATGAAAATAATAAACAAAAAACTAAGTAACAAATTACTGTTTTTTTCAGTAATTAGTGTTTTAATACCAATATTGATACT
GAGTTTTGTTGCAAATGACACTATTGAAAACATTTTAGACAATAATGCTAGATCATGTGTAGAAACGAGTATGAATACAT
TAAATCAATTAATTAATGTTAGAACTGTAGAAATTGGAAGTATTTGTGAATATTCGACAACTACTCCTGGAATAATTAAC
GGAATACTAAATCGAGATGAAAAAGAACTACTTCTTAGAATTCAAAATTTTAAAGATACTACAAATACAGATTTTATTGG
GATAGTTGATTCTAATGGACATATAATTACGTCAACAGCAGGAAAAGATGTTCAACTTGGAAATATTGTAACTAATATGA
GAAGTCAAGGTGTTGAAACTTCTTTTGAAATAATTTCAGATAATGCTGCATCTAAAATGAATAAAAATTATAAAGTTGAA
GGAGTAGCGGGTGCACTTTCATTAGTTATTGTAAAACCGGTTTATAGTGATGGGAAATATATTGGTTCAATTGTTGCAGT
TGAAATCCTTAACAATAACTACAATATAGTAGACGACGTAAAAAGACTTACTGGTGATGATGCATCAATTACTTTTGAAG
ATAAACGGATAAGTACTACTATCATTCGAGATGGAAGAAGAACCGTTAGTTTGGCAGTTTCTAATGGTATTTGGAGCCAA
GTTTATTCGAATCAACCTTATTTTGGGACTACTGATGTTTTAGGGGTTCAATATCTTACGGCATACTATCCAATTTATGA
TTCAAATAAAAAACCCGTTGGTATGATTGTTGTAGGTTCCCCTCAAACAAATGCAATTTTAGCAAAAAATGAAGCTAGAA
ACAGAATGATTTTAGTTGCATTAATTGGTACTATATTAGCTGTTTTAATATCTTTAATCACAAGTAAAAAAATAACAAAG
CCAGTTGAAGAGTTAAAACATGCAACTGAAGAATTTGGTAAGGGAAATTATGAATATAAGTCAGATATTAAAACTGGCGA
TGAATTAGAAGTATTATCAAATTCTTTTAATTCAATGGCTGAAAATGTTAAAAATTTAATGAAAACAATGGATATGGATA
AAGCAGAACTTGCAAAACTATTATCTGAAGTAACTACTGTAATGAACAACGTTTCAAAAGGAGACTTTACAGCAAGGGCA
AATGAAAATTCTAAAAATAACGAGTTACAAGTAGCAATCAATAAAGCAGTTTCAAACGTTGCTGTTTTAATTAAGGATTT
AAGAGAAGAAGTTACTTTATTAAATAAACAAGTTGTTAAATTAGAAGAACAGTCAAGTGGTGCAGAAGAAACTTCTAGTC
AGGTTGCAGATGCTGCAAATCAAGTTGCAACCGCTGCAAGCGACCAATCTGCAAAAGTTCAAGATATTTCAGATATGATT
GAAGAAGTATATGAAGGAACTAAAAATTCATACAAAAATGCAGAAGAAACCGTGAAAGCAACATCTGAAATTTCAGAAAA
CTCTGAAAACGGGGTTAAAAAGGTTGAAAATGCAATAAAAAGAATGCAGACAATTACAAACGTAATTGATGACCTTGGAC
GGTCAATTCAAATGCTTGGCGAAGATGGTAAAAAAATTAATGAAGTTACTGGACTAATTAAAGATATCGCTGAACAAACT
GGCCTTTTAGCACTGAATGCTTCAATTGAAGCAGCAAGGGCAGGTGAAGCTGGAAAGGGTTTTGCAGTTGTTGCAAGTGA
AATTAAGGCTTTAGCAGAAGAAATTAAAAAGTCAGTTGAAAATATTAATCAGACAATTAATGGAGTTCATAAACGAATCG
ATGAAACCGTTAAACTTGGAAATAAGGGTAAAGATGAAGTTGATAAAGGAGTAGTTGCAATTGATGATGTAAACAATGCA
CTTTTAAAAATTAATGAAAGTGTGAGTGGTGCAGTAATAAAGATAAATGGAATTAAAGATAATGCGAAATCTTCTGAAAT
AAATACTGAAAAAGTATTAAAAAGTGCTCAGGATATTGCAGCACTTTCAGAAGAATTTGCAGCAACTGCAGAAGAATTAA
CTGCATCAACTGAAGAATTATCTTCAATAATTGAGGAAATGAAACACGTATCCGAAGAAGTAGGTTCAGTTTCAAACAAC
ATTTCTGAAAAATCAAGTCGATTTAACATTTAA

Upstream 100 bases:

>100_bases
TTTCACCTTTTATTTTAAACTTTTGCCCACGTGAAAAAGATATAAACCCATAAAATAAAGATTATTGTATGGGCATTATT
TAGTGTACTTGGGTGCTAGT

Downstream 100 bases:

>100_bases
TATTCTTTTCTTTCCATTTTTTTGTCTGAAAGCGTTTTTACCAAATTTAAAGAAATTTCTCCTTCAACTGAAATATATCC
ATTAATTAAAGCCCTATCAA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 730; Mature: 730

Protein sequence:

>730_residues
MKIINKKLSNKLLFFSVISVLIPILILSFVANDTIENILDNNARSCVETSMNTLNQLINVRTVEIGSICEYSTTTPGIIN
GILNRDEKELLLRIQNFKDTTNTDFIGIVDSNGHIITSTAGKDVQLGNIVTNMRSQGVETSFEIISDNAASKMNKNYKVE
GVAGALSLVIVKPVYSDGKYIGSIVAVEILNNNYNIVDDVKRLTGDDASITFEDKRISTTIIRDGRRTVSLAVSNGIWSQ
VYSNQPYFGTTDVLGVQYLTAYYPIYDSNKKPVGMIVVGSPQTNAILAKNEARNRMILVALIGTILAVLISLITSKKITK
PVEELKHATEEFGKGNYEYKSDIKTGDELEVLSNSFNSMAENVKNLMKTMDMDKAELAKLLSEVTTVMNNVSKGDFTARA
NENSKNNELQVAINKAVSNVAVLIKDLREEVTLLNKQVVKLEEQSSGAEETSSQVADAANQVATAASDQSAKVQDISDMI
EEVYEGTKNSYKNAEETVKATSEISENSENGVKKVENAIKRMQTITNVIDDLGRSIQMLGEDGKKINEVTGLIKDIAEQT
GLLALNASIEAARAGEAGKGFAVVASEIKALAEEIKKSVENINQTINGVHKRIDETVKLGNKGKDEVDKGVVAIDDVNNA
LLKINESVSGAVIKINGIKDNAKSSEINTEKVLKSAQDIAALSEEFAATAEELTASTEELSSIIEEMKHVSEEVGSVSNN
ISEKSSRFNI

Sequences:

>Translated_730_residues
MKIINKKLSNKLLFFSVISVLIPILILSFVANDTIENILDNNARSCVETSMNTLNQLINVRTVEIGSICEYSTTTPGIIN
GILNRDEKELLLRIQNFKDTTNTDFIGIVDSNGHIITSTAGKDVQLGNIVTNMRSQGVETSFEIISDNAASKMNKNYKVE
GVAGALSLVIVKPVYSDGKYIGSIVAVEILNNNYNIVDDVKRLTGDDASITFEDKRISTTIIRDGRRTVSLAVSNGIWSQ
VYSNQPYFGTTDVLGVQYLTAYYPIYDSNKKPVGMIVVGSPQTNAILAKNEARNRMILVALIGTILAVLISLITSKKITK
PVEELKHATEEFGKGNYEYKSDIKTGDELEVLSNSFNSMAENVKNLMKTMDMDKAELAKLLSEVTTVMNNVSKGDFTARA
NENSKNNELQVAINKAVSNVAVLIKDLREEVTLLNKQVVKLEEQSSGAEETSSQVADAANQVATAASDQSAKVQDISDMI
EEVYEGTKNSYKNAEETVKATSEISENSENGVKKVENAIKRMQTITNVIDDLGRSIQMLGEDGKKINEVTGLIKDIAEQT
GLLALNASIEAARAGEAGKGFAVVASEIKALAEEIKKSVENINQTINGVHKRIDETVKLGNKGKDEVDKGVVAIDDVNNA
LLKINESVSGAVIKINGIKDNAKSSEINTEKVLKSAQDIAALSEEFAATAEELTASTEELSSIIEEMKHVSEEVGSVSNN
ISEKSSRFNI
>Mature_730_residues
MKIINKKLSNKLLFFSVISVLIPILILSFVANDTIENILDNNARSCVETSMNTLNQLINVRTVEIGSICEYSTTTPGIIN
GILNRDEKELLLRIQNFKDTTNTDFIGIVDSNGHIITSTAGKDVQLGNIVTNMRSQGVETSFEIISDNAASKMNKNYKVE
GVAGALSLVIVKPVYSDGKYIGSIVAVEILNNNYNIVDDVKRLTGDDASITFEDKRISTTIIRDGRRTVSLAVSNGIWSQ
VYSNQPYFGTTDVLGVQYLTAYYPIYDSNKKPVGMIVVGSPQTNAILAKNEARNRMILVALIGTILAVLISLITSKKITK
PVEELKHATEEFGKGNYEYKSDIKTGDELEVLSNSFNSMAENVKNLMKTMDMDKAELAKLLSEVTTVMNNVSKGDFTARA
NENSKNNELQVAINKAVSNVAVLIKDLREEVTLLNKQVVKLEEQSSGAEETSSQVADAANQVATAASDQSAKVQDISDMI
EEVYEGTKNSYKNAEETVKATSEISENSENGVKKVENAIKRMQTITNVIDDLGRSIQMLGEDGKKINEVTGLIKDIAEQT
GLLALNASIEAARAGEAGKGFAVVASEIKALAEEIKKSVENINQTINGVHKRIDETVKLGNKGKDEVDKGVVAIDDVNNA
LLKINESVSGAVIKINGIKDNAKSSEINTEKVLKSAQDIAALSEEFAATAEELTASTEELSSIIEEMKHVSEEVGSVSNN
ISEKSSRFNI

Specific function: Mediates Taxis To The Sugars Ribose And Galactose VIa An Interaction With The Periplasmic Ribose- Or Galactose-Binding Proteins. Chemotactic-Signal Transducers Respond To Changes In The Concentration Of Attractants And Repellents In The Environment, Trans

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=211, Percent_Identity=30.8056872037915, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI2367378, Length=163, Percent_Identity=30.0613496932515, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1788195, Length=193, Percent_Identity=27.4611398963731, Blast_Score=76, Evalue=8e-15,
Organism=Escherichia coli, GI1789453, Length=87, Percent_Identity=45.9770114942529, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1788194, Length=242, Percent_Identity=25.2066115702479, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 79335; Mature: 79335

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIINKKLSNKLLFFSVISVLIPILILSFVANDTIENILDNNARSCVETSMNTLNQLINV
CCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
RTVEIGSICEYSTTTPGIINGILNRDEKELLLRIQNFKDTTNTDFIGIVDSNGHIITSTA
EEEEECCCCCCCCCCCHHHHHHHCCCHHHHHHHHHCCCCCCCCCEEEEEECCCEEEEECC
GKDVQLGNIVTNMRSQGVETSFEIISDNAASKMNKNYKVEGVAGALSLVIVKPVYSDGKY
CCCEEHHHHHHHHHHCCCCCHHHHHCCCHHHHCCCCCEEEEHHHHEEHHEEECCCCCCCH
IGSIVAVEILNNNYNIVDDVKRLTGDDASITFEDKRISTTIIRDGRRTVSLAVSNGIWSQ
HHHHHEEEEECCCCCHHHHHHHHCCCCCEEEEECCHHEEHHHHCCCEEEEEEECCCHHHH
VYSNQPYFGTTDVLGVQYLTAYYPIYDSNKKPVGMIVVGSPQTNAILAKNEARNRMILVA
HHCCCCCCCCHHHHHHHHHHHHCCEECCCCCCEEEEEECCCCCCEEEECCCCCCCEEHHH
LIGTILAVLISLITSKKITKPVEELKHATEEFGKGNYEYKSDIKTGDELEVLSNSFNSMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
ENVKNLMKTMDMDKAELAKLLSEVTTVMNNVSKGDFTARANENSKNNELQVAINKAVSNV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEEHHHHHHHHH
AVLIKDLREEVTLLNKQVVKLEEQSSGAEETSSQVADAANQVATAASDQSAKVQDISDMI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
EEVYEGTKNSYKNAEETVKATSEISENSENGVKKVENAIKRMQTITNVIDDLGRSIQMLG
HHHHHCCCHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
EDGKKINEVTGLIKDIAEQTGLLALNASIEAARAGEAGKGFAVVASEIKALAEEIKKSVE
CCCHHHHHHHHHHHHHHHHCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
NINQTINGVHKRIDETVKLGNKGKDEVDKGVVAIDDVNNALLKINESVSGAVIKINGIKD
HHHHHHHHHHHHHHHHHHCCCCCCCHHHCCEEEEECCCCCCEEECCCCCCEEEEEECCCC
NAKSSEINTEKVLKSAQDIAALSEEFAATAEELTASTEELSSIIEEMKHVSEEVGSVSNN
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
ISEKSSRFNI
HHHHHHCCCC
>Mature Secondary Structure
MKIINKKLSNKLLFFSVISVLIPILILSFVANDTIENILDNNARSCVETSMNTLNQLINV
CCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
RTVEIGSICEYSTTTPGIINGILNRDEKELLLRIQNFKDTTNTDFIGIVDSNGHIITSTA
EEEEECCCCCCCCCCCHHHHHHHCCCHHHHHHHHHCCCCCCCCCEEEEEECCCEEEEECC
GKDVQLGNIVTNMRSQGVETSFEIISDNAASKMNKNYKVEGVAGALSLVIVKPVYSDGKY
CCCEEHHHHHHHHHHCCCCCHHHHHCCCHHHHCCCCCEEEEHHHHEEHHEEECCCCCCCH
IGSIVAVEILNNNYNIVDDVKRLTGDDASITFEDKRISTTIIRDGRRTVSLAVSNGIWSQ
HHHHHEEEEECCCCCHHHHHHHHCCCCCEEEEECCHHEEHHHHCCCEEEEEEECCCHHHH
VYSNQPYFGTTDVLGVQYLTAYYPIYDSNKKPVGMIVVGSPQTNAILAKNEARNRMILVA
HHCCCCCCCCHHHHHHHHHHHHCCEECCCCCCEEEEEECCCCCCEEEECCCCCCCEEHHH
LIGTILAVLISLITSKKITKPVEELKHATEEFGKGNYEYKSDIKTGDELEVLSNSFNSMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
ENVKNLMKTMDMDKAELAKLLSEVTTVMNNVSKGDFTARANENSKNNELQVAINKAVSNV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEEHHHHHHHHH
AVLIKDLREEVTLLNKQVVKLEEQSSGAEETSSQVADAANQVATAASDQSAKVQDISDMI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
EEVYEGTKNSYKNAEETVKATSEISENSENGVKKVENAIKRMQTITNVIDDLGRSIQMLG
HHHHHCCCHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
EDGKKINEVTGLIKDIAEQTGLLALNASIEAARAGEAGKGFAVVASEIKALAEEIKKSVE
CCCHHHHHHHHHHHHHHHHCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
NINQTINGVHKRIDETVKLGNKGKDEVDKGVVAIDDVNNALLKINESVSGAVIKINGIKD
HHHHHHHHHHHHHHHHHHCCCCCCCHHHCCEEEEECCCCCCEEECCCCCCEEEEEECCCC
NAKSSEINTEKVLKSAQDIAALSEEFAATAEELTASTEELSSIIEEMKHVSEEVGSVSNN
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
ISEKSSRFNI
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7921238; 7704255; 8969502; 9384377 [H]