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The map label for this gene is 150399457

Identifier: 150399457

GI number: 150399457

Start: 755128

End: 757458

Strand: Reverse

Name: 150399457

Synonym: Mevan_0706

Alternate gene names: NA

Gene position: 757458-755128 (Counterclockwise)

Preceding gene: 150399458

Following gene: 150399456

Centisome position: 44.04

GC content: 29.82

Gene sequence:

>2331_bases
TTGCACATAAATCATCCATTAATAAAAAATAATATAATTGAAGCGAGAATTTACCAACAACTCGTAGTTGCAAATGCGTT
AAAGCAAAATACTTTGTGTGTTCTTGGAACAGGTTTAGGTAAAACTGCAATTGCAGCACTTACTATTGCAGGAATTTTAT
CAAAAAGAAATGGAAAAGTTTTAATTATTGCACCATCAAGACCCCTTGTAGATCAGCACCAAAAAAGTATGAATTCATTT
TTAAATATTGACCCAGAAAAAATAATTGTTTTAAATGGAAAAATTTCCCCTTTAAAACGAGAAGAAATGTGGAAAACCGG
GAAAATTTTTATTGCAACTCCTCAAGTTGCAGAAAATGATATAATTTCTGGAATTTTAAAGACAAAAGATTTTTCACTTT
TAATTGCAGATGAAGCACATCACACAACGGGAAATCATTCTTACACTTTTGTTGCAAATACTTTTAAACAAAATTCCCAT
ATTTTGGGTTTAACGGCATCTCCGGGTTCAAATATTGAAAAAATAATGGAAATATGTGAGAATTTAGGGGTTGAACACGT
CGAAATTAAAACTGAAGAAGATCCAGATGTTTTACCATATGTTGCAAAAGTTAAAATGAGGCCTAGAAAGGTAGAACTTC
CAAAAGAGTTTTTAGACAATTTAAAACTTTTGAAAAACGCATTAAAAGAACGTCTAACTATATTAAAAGATAATAAAGTA
ATTTATACTATAAACGTAAATAAATCCGACTTAATTGGGTTAAATAAAAAAATAATGACAATGGACGATTCAATTAAATA
CGAGATGTTAAAAGTGTCATCAGAAGCAGTTAAAATTGAACACGCAATAGAAATGCTTGAAACCCAAGGAAAAAGCACTT
TTTTAAATTACTATCAAAAAATGCTCTCACAAAACACGAAATCTGCAAAAAGTATTACATTAGACCATAGATTTTTACAA
GTCGTTGAAAATTTAAATGAAATTAATATAGAACATCCAAAATACGATAAACTTCTTGAAATCACGAAAGAAATTTTAGA
GCAGAATGAAAAAATGATTATTTTTGCACAGTATCGCGATACAGTTCAAAAAATTGTAGAATTACTCTCTAAACATAACA
TCGAAGCAATAACGTTTGTTGGGCAGTCTAATAAAGATGGAAAAGGAATGAGCCAAAAAGAACAGATAAAAGCTATTGAA
CGGTTTAAATCTGATGCAAATGTGCTTGTTTCAACAAGCGTTTCTGAGGAAGGAATAGACATTTCAAGCGTTAATTATGT
TTTATTTTACGAACCAGTTCCTTCAGAAATTAGAATGATTCAGCGAAGAGGACGTGCTGCAAGAGGCGAAGGTGGCGAAG
TAATAGTATTAATTGCCGAAAAAACACGAGATGAGGGTTATTACCGAGCAGGAATTTCTAAAGAAAAAAATATGAAAAAT
ATATTAAAAAATATGCAAGAAACACTAAATAAAAAACTTTCAGAGTCAAAATTTGAAAATTCTGAAATCAAAAATGAAAA
AAATAATAATTTGAATTTAAATAATATTGCAAGATTAAAAGCTGATGAAACAGTACTTAAAAAAGAAAATAGCGCCGTTA
AACTTGAAAATGAATCTAAATCCGAAACTCTGGATTACCTACTTACAGATAATATTGAAAGAGGCTTTGAAAATAAAAGT
TTGGCAAAAATAATAATTGATTCAAGAGAACGGCATATCGGTAGATACATCTCAAAAAAAGCAAATCTGGAATTTAAAAC
CCTCGAAATCGGAGATTATATCGTGAGTGACAGGGTTGCAGTTGAAAGAAAAACTGCAGAAGATTTTGAAAGCTCAATAA
TCGATAAAAGATTGTTTAATCAACTTATCGATTTAAAAAAATATGAAAAACCGCTTTTAATAATTGAAGGAGATAATTTT
TACAGACTTCGTGAAAATGCAATACAAGGAACGATATTTTCTATAATGATAGACTACCAAATTCCGATAATCTTTTCAAA
AAATATGGAAGATACTGCAAATATTTTAGTGAAAATTGCAGAAAAAGAGCAATTAAAGGAAAAGAGAGGAATATCTATAC
GATATGGTAAAAGACTAATGTCGATAAAAGAAAGGCAGAAGTTTTTGGTTGAAGGACTTCCCGATATTGGGCCAGTAATG
GCGGAAAATCTTTTAAATAGCCTTCAAACGGTTGAAAAAATATTTGGTGCAAGTGAAAAAGAATTAACCGCAGTTGAAGG
GATTGGAAAAATTACGGCTAAAAAAATACGTGAAGTAGTTACTAAAACTTATAACGAAAAAAATACAATGAAAAATGAGG
ATTTATTATGA

Upstream 100 bases:

>100_bases
AACTCCACCTAATCCCTTTCCACTAGCTATATATTTTATAAATACCTATTTTTTAAAGAAGAATGAAAATTTATTACTGT
CGACTTTAAGGTGTTGAATT

Downstream 100 bases:

>100_bases
TATGCATACCAATAATTGATAATACGGTAGAAAAAGCGTTAATTTCAGCAAAAGAAGCTTTAAAATATGGTGATATTGTT
GAATTTCGGCTTGATTTACT

Product: Hef nuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 776; Mature: 776

Protein sequence:

>776_residues
MHINHPLIKNNIIEARIYQQLVVANALKQNTLCVLGTGLGKTAIAALTIAGILSKRNGKVLIIAPSRPLVDQHQKSMNSF
LNIDPEKIIVLNGKISPLKREEMWKTGKIFIATPQVAENDIISGILKTKDFSLLIADEAHHTTGNHSYTFVANTFKQNSH
ILGLTASPGSNIEKIMEICENLGVEHVEIKTEEDPDVLPYVAKVKMRPRKVELPKEFLDNLKLLKNALKERLTILKDNKV
IYTINVNKSDLIGLNKKIMTMDDSIKYEMLKVSSEAVKIEHAIEMLETQGKSTFLNYYQKMLSQNTKSAKSITLDHRFLQ
VVENLNEINIEHPKYDKLLEITKEILEQNEKMIIFAQYRDTVQKIVELLSKHNIEAITFVGQSNKDGKGMSQKEQIKAIE
RFKSDANVLVSTSVSEEGIDISSVNYVLFYEPVPSEIRMIQRRGRAARGEGGEVIVLIAEKTRDEGYYRAGISKEKNMKN
ILKNMQETLNKKLSESKFENSEIKNEKNNNLNLNNIARLKADETVLKKENSAVKLENESKSETLDYLLTDNIERGFENKS
LAKIIIDSRERHIGRYISKKANLEFKTLEIGDYIVSDRVAVERKTAEDFESSIIDKRLFNQLIDLKKYEKPLLIIEGDNF
YRLRENAIQGTIFSIMIDYQIPIIFSKNMEDTANILVKIAEKEQLKEKRGISIRYGKRLMSIKERQKFLVEGLPDIGPVM
AENLLNSLQTVEKIFGASEKELTAVEGIGKITAKKIREVVTKTYNEKNTMKNEDLL

Sequences:

>Translated_776_residues
MHINHPLIKNNIIEARIYQQLVVANALKQNTLCVLGTGLGKTAIAALTIAGILSKRNGKVLIIAPSRPLVDQHQKSMNSF
LNIDPEKIIVLNGKISPLKREEMWKTGKIFIATPQVAENDIISGILKTKDFSLLIADEAHHTTGNHSYTFVANTFKQNSH
ILGLTASPGSNIEKIMEICENLGVEHVEIKTEEDPDVLPYVAKVKMRPRKVELPKEFLDNLKLLKNALKERLTILKDNKV
IYTINVNKSDLIGLNKKIMTMDDSIKYEMLKVSSEAVKIEHAIEMLETQGKSTFLNYYQKMLSQNTKSAKSITLDHRFLQ
VVENLNEINIEHPKYDKLLEITKEILEQNEKMIIFAQYRDTVQKIVELLSKHNIEAITFVGQSNKDGKGMSQKEQIKAIE
RFKSDANVLVSTSVSEEGIDISSVNYVLFYEPVPSEIRMIQRRGRAARGEGGEVIVLIAEKTRDEGYYRAGISKEKNMKN
ILKNMQETLNKKLSESKFENSEIKNEKNNNLNLNNIARLKADETVLKKENSAVKLENESKSETLDYLLTDNIERGFENKS
LAKIIIDSRERHIGRYISKKANLEFKTLEIGDYIVSDRVAVERKTAEDFESSIIDKRLFNQLIDLKKYEKPLLIIEGDNF
YRLRENAIQGTIFSIMIDYQIPIIFSKNMEDTANILVKIAEKEQLKEKRGISIRYGKRLMSIKERQKFLVEGLPDIGPVM
AENLLNSLQTVEKIFGASEKELTAVEGIGKITAKKIREVVTKTYNEKNTMKNEDLL
>Mature_776_residues
MHINHPLIKNNIIEARIYQQLVVANALKQNTLCVLGTGLGKTAIAALTIAGILSKRNGKVLIIAPSRPLVDQHQKSMNSF
LNIDPEKIIVLNGKISPLKREEMWKTGKIFIATPQVAENDIISGILKTKDFSLLIADEAHHTTGNHSYTFVANTFKQNSH
ILGLTASPGSNIEKIMEICENLGVEHVEIKTEEDPDVLPYVAKVKMRPRKVELPKEFLDNLKLLKNALKERLTILKDNKV
IYTINVNKSDLIGLNKKIMTMDDSIKYEMLKVSSEAVKIEHAIEMLETQGKSTFLNYYQKMLSQNTKSAKSITLDHRFLQ
VVENLNEINIEHPKYDKLLEITKEILEQNEKMIIFAQYRDTVQKIVELLSKHNIEAITFVGQSNKDGKGMSQKEQIKAIE
RFKSDANVLVSTSVSEEGIDISSVNYVLFYEPVPSEIRMIQRRGRAARGEGGEVIVLIAEKTRDEGYYRAGISKEKNMKN
ILKNMQETLNKKLSESKFENSEIKNEKNNNLNLNNIARLKADETVLKKENSAVKLENESKSETLDYLLTDNIERGFENKS
LAKIIIDSRERHIGRYISKKANLEFKTLEIGDYIVSDRVAVERKTAEDFESSIIDKRLFNQLIDLKKYEKPLLIIEGDNF
YRLRENAIQGTIFSIMIDYQIPIIFSKNMEDTANILVKIAEKEQLKEKRGISIRYGKRLMSIKERQKFLVEGLPDIGPVM
AENLLNSLQTVEKIFGASEKELTAVEGIGKITAKKIREVVTKTYNEKNTMKNEDLL

Specific function: Unknown

COG id: COG1111

COG function: function code L; ERCC4-like helicases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI74959747, Length=536, Percent_Identity=27.9850746268657, Blast_Score=204, Evalue=2e-52,
Organism=Homo sapiens, GI27886568, Length=540, Percent_Identity=26.6666666666667, Blast_Score=99, Evalue=2e-20,
Organism=Homo sapiens, GI27881482, Length=508, Percent_Identity=24.8031496062992, Blast_Score=96, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6322192, Length=537, Percent_Identity=28.6778398510242, Blast_Score=186, Evalue=9e-48,
Organism=Drosophila melanogaster, GI116008407, Length=545, Percent_Identity=27.5229357798165, Blast_Score=202, Evalue=8e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR020819
- InterPro:   IPR006166
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR000445
- InterPro:   IPR003583
- InterPro:   IPR011335
- InterPro:   IPR010994 [H]

Pfam domain/function: PF00270 DEAD; PF02732 ERCC4; PF00271 Helicase_C; PF00633 HHH [H]

EC number: =3.6.4.13 [H]

Molecular weight: Translated: 88385; Mature: 88385

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHINHPLIKNNIIEARIYQQLVVANALKQNTLCVLGTGLGKTAIAALTIAGILSKRNGKV
CCCCCCCHHCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCEE
LIIAPSRPLVDQHQKSMNSFLNIDPEKIIVLNGKISPLKREEMWKTGKIFIATPQVAEND
EEEECCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHCCCCCEEEECCCHHHHH
IISGILKTKDFSLLIADEAHHTTGNHSYTFVANTFKQNSHILGLTASPGSNIEKIMEICE
HHHHHHCCCCCEEEEECCCCCCCCCCEEEEEEEEECCCCEEEEEECCCCCCHHHHHHHHH
NLGVEHVEIKTEEDPDVLPYVAKVKMRPRKVELPKEFLDNLKLLKNALKERLTILKDNKV
HCCCEEEEEECCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCEE
IYTINVNKSDLIGLNKKIMTMDDSIKYEMLKVSSEAVKIEHAIEMLETQGKSTFLNYYQK
EEEEECCCHHHCCCCCEEEECCCCCHHHHEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
MLSQNTKSAKSITLDHRFLQVVENLNEINIEHPKYDKLLEITKEILEQNEKMIIFAQYRD
HHHCCCCCHHEEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEEHHHH
TVQKIVELLSKHNIEAITFVGQSNKDGKGMSQKEQIKAIERFKSDANVLVSTSVSEEGID
HHHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCC
ISSVNYVLFYEPVPSEIRMIQRRGRAARGEGGEVIVLIAEKTRDEGYYRAGISKEKNMKN
EECEEEEEEECCCCHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCEEECCCCCCHHHHH
ILKNMQETLNKKLSESKFENSEIKNEKNNNLNLNNIARLKADETVLKKENSAVKLENESK
HHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCEEEECCCHHHHHCCCCEEEECCCCC
SETLDYLLTDNIERGFENKSLAKIIIDSRERHIGRYISKKANLEFKTLEIGDYIVSDRVA
HHHHHHHHHCCHHCCCCCCCHHHHHHCCHHHHHHHHHHHHCCCEEEEEEECCCHHCCCHH
VERKTAEDFESSIIDKRLFNQLIDLKKYEKPLLIIEGDNFYRLRENAIQGTIFSIMIDYQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEHHHHHCCEEEEEEEEEE
IPIIFSKNMEDTANILVKIAEKEQLKEKRGISIRYGKRLMSIKERQKFLVEGLPDIGPVM
EEEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHCCCCCHHHH
AENLLNSLQTVEKIFGASEKELTAVEGIGKITAKKIREVVTKTYNEKNTMKNEDLL
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MHINHPLIKNNIIEARIYQQLVVANALKQNTLCVLGTGLGKTAIAALTIAGILSKRNGKV
CCCCCCCHHCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCEE
LIIAPSRPLVDQHQKSMNSFLNIDPEKIIVLNGKISPLKREEMWKTGKIFIATPQVAEND
EEEECCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHCCCCCEEEECCCHHHHH
IISGILKTKDFSLLIADEAHHTTGNHSYTFVANTFKQNSHILGLTASPGSNIEKIMEICE
HHHHHHCCCCCEEEEECCCCCCCCCCEEEEEEEEECCCCEEEEEECCCCCCHHHHHHHHH
NLGVEHVEIKTEEDPDVLPYVAKVKMRPRKVELPKEFLDNLKLLKNALKERLTILKDNKV
HCCCEEEEEECCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCEE
IYTINVNKSDLIGLNKKIMTMDDSIKYEMLKVSSEAVKIEHAIEMLETQGKSTFLNYYQK
EEEEECCCHHHCCCCCEEEECCCCCHHHHEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
MLSQNTKSAKSITLDHRFLQVVENLNEINIEHPKYDKLLEITKEILEQNEKMIIFAQYRD
HHHCCCCCHHEEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEEHHHH
TVQKIVELLSKHNIEAITFVGQSNKDGKGMSQKEQIKAIERFKSDANVLVSTSVSEEGID
HHHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCC
ISSVNYVLFYEPVPSEIRMIQRRGRAARGEGGEVIVLIAEKTRDEGYYRAGISKEKNMKN
EECEEEEEEECCCCHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCEEECCCCCCHHHHH
ILKNMQETLNKKLSESKFENSEIKNEKNNNLNLNNIARLKADETVLKKENSAVKLENESK
HHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCEEEECCCHHHHHCCCCEEEECCCCC
SETLDYLLTDNIERGFENKSLAKIIIDSRERHIGRYISKKANLEFKTLEIGDYIVSDRVA
HHHHHHHHHCCHHCCCCCCCHHHHHHCCHHHHHHHHHHHHCCCEEEEEEECCCHHCCCHH
VERKTAEDFESSIIDKRLFNQLIDLKKYEKPLLIIEGDNFYRLRENAIQGTIFSIMIDYQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEHHHHHCCEEEEEEEEEE
IPIIFSKNMEDTANILVKIAEKEQLKEKRGISIRYGKRLMSIKERQKFLVEGLPDIGPVM
EEEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHCCCCCHHHH
AENLLNSLQTVEKIFGASEKELTAVEGIGKITAKKIREVVTKTYNEKNTMKNEDLL
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]