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The map label for this gene is yfbQ [C]

Identifier: 150399458

GI number: 150399458

Start: 757630

End: 758931

Strand: Reverse

Name: yfbQ [C]

Synonym: Mevan_0707

Alternate gene names: 150399458

Gene position: 758931-757630 (Counterclockwise)

Preceding gene: 150399485

Following gene: 150399457

Centisome position: 44.12

GC content: 32.87

Gene sequence:

>1302_bases
ATGAGAACAGATATCGTAAGTTCGGGAGTTGGAGAATTGTCATATGAAATCAGGGAAATTGTGAAGGTGGCGAAAAGGGC
CGAAAATTCGGGATTGGAAATTGTCTGGGAAAATATTGGGGATCCAATTGCCAAGGGGGAAAAGCTTCCACACTGGATAA
AGGAAATTGTCGCAGAAACTGCAATGGAAGATAGTTCATACGGGTACTGCCCTACAAAAGGCCTTCTTGAAACACGTGAA
TTTTTAGCAGATTTAAACAATAGTAGAAATGGAGCGAATATATCTTCTGAAGATATTTTATTTTTTAACGGCCTTGGAGA
TGCCATAACAAATATATATGGACTTTTAAGGAAAGAATGTCGTGTAATCGGGCCAAAACCTGCTTATTCAACACATTCTT
CTGCAGAAGGCCTTCATGCAAACTGTCATCCGGTAATGTATGAGTTAAATAAAGATGACAACTGGAATCCGGATATTGAA
GACCTTACTAATAAAATAAAATATAATCCTTCAATTGCAGGAATTTTACTTATAAATCCAGGAAATCCAACTGGTGCAGT
TTATTCGAAAAAAGTACTGAGTAATATCGTTGATATTGCAAATGAATATGATTTATTTATTTTAACTGACGAAATATATT
CAAATATTGTTTATAACGGTAAAAAACATAATTATTTATCTGAAGTAATTGATGACGTTTCAGGAATTTCTTTAAAAGGC
ATTTCAAAAGATCTTCCGTGGCCAGGTTCACGATGCGGTTGGGCAGAGTTTTATAATGTTGAAAAAGACCCGATTTTCCA
TAAATACGTTGAAAACATATGTAAGTTTAAAATGATTGAAGTATGTTCAACAACGCTCCCTCAAAAAGTAATTCCAAGAG
TAATGTCCGATAACAGGTATGGTAAATATCTAGAAGAGCGAAAAAAACACTATGAATATGCTTCAAACTATGTTTACGAT
AGAATGAAAAAAATCGAAGGAGTTACGGTAAATAAAACTAACGGTGCATTTTACAACACATTAGTTTTAGAGAAAGAATA
TTTAAATGAAGATCAATCATTGAAAATTGAAGATAATGGACTTAAAAATTATATTGAAACTATTTCAAAGGGAATCCCAA
ATGACAAGAGGTTCGTATACTACCTTCTTGGTTCAACAGGAATTTGCACTGTTCCTTTAACATCCTTTTGTTCTGAACAC
AATGGCCTTAGATTTACACTTCTTGAAAGAAATATGGAAATTATGAATAACACATTTGAGATAATGGCTGAAAAAATTGA
AGAATATATTTTAAGTAATTAA

Upstream 100 bases:

>100_bases
ATACGAAGTATTAGAATCAAAATTTAAAAAAATGTAAAACACTTAAAAACAGTTAAAAACACTTAAAATTCAAGTTTTAA
CCCAGTTGGAGGTGGAAGCA

Downstream 100 bases:

>100_bases
TTTTACTATCTTAATTTTAATATTCTTTTAATGTTATTTTTAAACGTTATTTTGTAAATGCTATTTTTTTTAACTCCACC
TAATCCCTTTCCACTAGCTA

Product: aminotransferase

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MRTDIVSSGVGELSYEIREIVKVAKRAENSGLEIVWENIGDPIAKGEKLPHWIKEIVAETAMEDSSYGYCPTKGLLETRE
FLADLNNSRNGANISSEDILFFNGLGDAITNIYGLLRKECRVIGPKPAYSTHSSAEGLHANCHPVMYELNKDDNWNPDIE
DLTNKIKYNPSIAGILLINPGNPTGAVYSKKVLSNIVDIANEYDLFILTDEIYSNIVYNGKKHNYLSEVIDDVSGISLKG
ISKDLPWPGSRCGWAEFYNVEKDPIFHKYVENICKFKMIEVCSTTLPQKVIPRVMSDNRYGKYLEERKKHYEYASNYVYD
RMKKIEGVTVNKTNGAFYNTLVLEKEYLNEDQSLKIEDNGLKNYIETISKGIPNDKRFVYYLLGSTGICTVPLTSFCSEH
NGLRFTLLERNMEIMNNTFEIMAEKIEEYILSN

Sequences:

>Translated_433_residues
MRTDIVSSGVGELSYEIREIVKVAKRAENSGLEIVWENIGDPIAKGEKLPHWIKEIVAETAMEDSSYGYCPTKGLLETRE
FLADLNNSRNGANISSEDILFFNGLGDAITNIYGLLRKECRVIGPKPAYSTHSSAEGLHANCHPVMYELNKDDNWNPDIE
DLTNKIKYNPSIAGILLINPGNPTGAVYSKKVLSNIVDIANEYDLFILTDEIYSNIVYNGKKHNYLSEVIDDVSGISLKG
ISKDLPWPGSRCGWAEFYNVEKDPIFHKYVENICKFKMIEVCSTTLPQKVIPRVMSDNRYGKYLEERKKHYEYASNYVYD
RMKKIEGVTVNKTNGAFYNTLVLEKEYLNEDQSLKIEDNGLKNYIETISKGIPNDKRFVYYLLGSTGICTVPLTSFCSEH
NGLRFTLLERNMEIMNNTFEIMAEKIEEYILSN
>Mature_433_residues
MRTDIVSSGVGELSYEIREIVKVAKRAENSGLEIVWENIGDPIAKGEKLPHWIKEIVAETAMEDSSYGYCPTKGLLETRE
FLADLNNSRNGANISSEDILFFNGLGDAITNIYGLLRKECRVIGPKPAYSTHSSAEGLHANCHPVMYELNKDDNWNPDIE
DLTNKIKYNPSIAGILLINPGNPTGAVYSKKVLSNIVDIANEYDLFILTDEIYSNIVYNGKKHNYLSEVIDDVSGISLKG
ISKDLPWPGSRCGWAEFYNVEKDPIFHKYVENICKFKMIEVCSTTLPQKVIPRVMSDNRYGKYLEERKKHYEYASNYVYD
RMKKIEGVTVNKTNGAFYNTLVLEKEYLNEDQSLKIEDNGLKNYIETISKGIPNDKRFVYYLLGSTGICTVPLTSFCSEH
NGLRFTLLERNMEIMNNTFEIMAEKIEEYILSN

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=384, Percent_Identity=24.21875, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI4885351, Length=461, Percent_Identity=21.6919739696312, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI19263340, Length=455, Percent_Identity=20.8791208791209, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI215599424, Length=375, Percent_Identity=21.8666666666667, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1788627, Length=357, Percent_Identity=29.4117647058824, Blast_Score=149, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI17567663, Length=348, Percent_Identity=25.2873563218391, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71981209, Length=440, Percent_Identity=24.3181818181818, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71981215, Length=289, Percent_Identity=24.9134948096886, Blast_Score=71, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6320317, Length=363, Percent_Identity=29.2011019283747, Blast_Score=125, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6323118, Length=390, Percent_Identity=24.6153846153846, Blast_Score=102, Evalue=1e-22,
Organism=Drosophila melanogaster, GI18859735, Length=344, Percent_Identity=26.1627906976744, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI45551451, Length=455, Percent_Identity=25.0549450549451, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24641770, Length=455, Percent_Identity=25.0549450549451, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24641760, Length=455, Percent_Identity=25.0549450549451, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24641768, Length=455, Percent_Identity=25.0549450549451, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24641766, Length=455, Percent_Identity=25.0549450549451, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24641764, Length=455, Percent_Identity=25.0549450549451, Blast_Score=86, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 49234; Mature: 49234

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTDIVSSGVGELSYEIREIVKVAKRAENSGLEIVWENIGDPIAKGEKLPHWIKEIVAET
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEHHCCCHHHCCCCCHHHHHHHHHHH
AMEDSSYGYCPTKGLLETREFLADLNNSRNGANISSEDILFFNGLGDAITNIYGLLRKEC
HHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHH
RVIGPKPAYSTHSSAEGLHANCHPVMYELNKDDNWNPDIEDLTNKIKYNPSIAGILLINP
HCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCEEEEEEECC
GNPTGAVYSKKVLSNIVDIANEYDLFILTDEIYSNIVYNGKKHNYLSEVIDDVSGISLKG
CCCCCHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCHHHHHHHHHHHCCCEECC
ISKDLPWPGSRCGWAEFYNVEKDPIFHKYVENICKFKMIEVCSTTLPQKVIPRVMSDNRY
CCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCH
GKYLEERKKHYEYASNYVYDRMKKIEGVTVNKTNGAFYNTLVLEKEYLNEDQSLKIEDNG
HHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCEEHHEEEEHHHCCCCCCEEEECCH
LKNYIETISKGIPNDKRFVYYLLGSTGICTVPLTSFCSEHNGLRFTLLERNMEIMNNTFE
HHHHHHHHHHCCCCCCEEEEEEECCCCEEECCHHHHHCCCCCCEEEEECCCHHHHHHHHH
IMAEKIEEYILSN
HHHHHHHHHHCCC
>Mature Secondary Structure
MRTDIVSSGVGELSYEIREIVKVAKRAENSGLEIVWENIGDPIAKGEKLPHWIKEIVAET
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEHHCCCHHHCCCCCHHHHHHHHHHH
AMEDSSYGYCPTKGLLETREFLADLNNSRNGANISSEDILFFNGLGDAITNIYGLLRKEC
HHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHH
RVIGPKPAYSTHSSAEGLHANCHPVMYELNKDDNWNPDIEDLTNKIKYNPSIAGILLINP
HCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCEEEEEEECC
GNPTGAVYSKKVLSNIVDIANEYDLFILTDEIYSNIVYNGKKHNYLSEVIDDVSGISLKG
CCCCCHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCHHHHHHHHHHHCCCEECC
ISKDLPWPGSRCGWAEFYNVEKDPIFHKYVENICKFKMIEVCSTTLPQKVIPRVMSDNRY
CCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCH
GKYLEERKKHYEYASNYVYDRMKKIEGVTVNKTNGAFYNTLVLEKEYLNEDQSLKIEDNG
HHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCEEHHEEEEHHHCCCCCCEEEECCH
LKNYIETISKGIPNDKRFVYYLLGSTGICTVPLTSFCSEHNGLRFTLLERNMEIMNNTFE
HHHHHHHHHHCCCCCCEEEEEEECCCCEEECCHHHHHCCCCCCEEEEECCCHHHHHHHHH
IMAEKIEEYILSN
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]