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The map label for this gene is trpD

Identifier: 150399086

GI number: 150399086

Start: 380902

End: 381867

Strand: Reverse

Name: trpD

Synonym: Mevan_0332

Alternate gene names: 150399086

Gene position: 381867-380902 (Counterclockwise)

Preceding gene: 150399087

Following gene: 150399085

Centisome position: 22.2

GC content: 34.06

Gene sequence:

>966_bases
ATGCTTAATAAGCTTGTAGAATGTGAAAACCTCACTTTTGAAGAATCATACGAATTATTTAACATGCTTTTAGAGGAAAG
TGAAATACGAATTGCAGCATATTTAACGGCTTTACAGACAAAAGGCGTTACTGCTGATGAAATTGCAGGATTTGCAAAAG
CAATGAGGGATAATGCGGTTAAAATTGATTTAGGGGAAGTTACGGATACTTGCGGAACCGGTGGAGATGGTTCAAAAACA
ATAAACGTTAGCACAGCAGTTTCGATAATATTAGCATGCTTTACGAAAGTTGCAAAACACGGAAACGTTTCAGTTACTTC
AAAAAGCGGTTCAGCAAACGTTTATGAGGCATTGGGATGTAAAATTTTGGAAAATCCAGATGAAGCGAAAGTTTCAATTG
AAAAAACAAATTTTGCATTTTTATTTGCTCCAAAATACCACCCAGCACTTAAAAAAATAATGCCTGTAAGAAGTGAATTG
AAAATAAAAACTGTATTTAACATATTGGGCCCTTTAGCAAACCCTGCAAATCCTAAATATCAAATACTTGGGGTAAATTC
TCCAGAACTTTCTGAAAAAGTAGCAAATGCCCTATCAAAAGTTGGCGGCGTTAAAAAAGCACTAGTTATAAATGGAAATG
GGCTTGACGAGTTAAATCCAAACGGGGCTTCAAAGATAACTGAATACAACGGAAAATTTGAAACCTACGAAATAACGCCA
GAAGACTTTGGATTGGAAAATACAAAAATAATTCCTTGTGAAAGCCCAAATGAAAGTGCAAGACGGTTAATTGATGTATT
TTCTGGAAAAATTAATGAAGATAGGAATTTTATATTGATGAATGCAGGAGCTGCACTTTATGCATCAGAAATTGTTTCTG
ACTTTTTAGAAGGTGTTGAAATTGCAAAAAATGCAATAGATTCGGGAAAAGTTCTTAAAAAGCTTGAGATGATAAAAAAT
GTATAA

Upstream 100 bases:

>100_bases
AACAGGCACTAAAGCATGCTAATGCTGCACTTATTGGAACATCATTTATGACAGCAAAATATCAAGAAGAATTCGTAAAA
AGCTTTGTTGAGGGAAAATA

Downstream 100 bases:

>100_bases
ATTGGATTACGTAAACCCGTTAAAACTTTATGGGGTTTTAAGGGATGAAGGAAAGTATCCAGTAATGCTTGAATCAAGAG
CTAAGGGGCAAATTAATGCA

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MLNKLVECENLTFEESYELFNMLLEESEIRIAAYLTALQTKGVTADEIAGFAKAMRDNAVKIDLGEVTDTCGTGGDGSKT
INVSTAVSIILACFTKVAKHGNVSVTSKSGSANVYEALGCKILENPDEAKVSIEKTNFAFLFAPKYHPALKKIMPVRSEL
KIKTVFNILGPLANPANPKYQILGVNSPELSEKVANALSKVGGVKKALVINGNGLDELNPNGASKITEYNGKFETYEITP
EDFGLENTKIIPCESPNESARRLIDVFSGKINEDRNFILMNAGAALYASEIVSDFLEGVEIAKNAIDSGKVLKKLEMIKN
V

Sequences:

>Translated_321_residues
MLNKLVECENLTFEESYELFNMLLEESEIRIAAYLTALQTKGVTADEIAGFAKAMRDNAVKIDLGEVTDTCGTGGDGSKT
INVSTAVSIILACFTKVAKHGNVSVTSKSGSANVYEALGCKILENPDEAKVSIEKTNFAFLFAPKYHPALKKIMPVRSEL
KIKTVFNILGPLANPANPKYQILGVNSPELSEKVANALSKVGGVKKALVINGNGLDELNPNGASKITEYNGKFETYEITP
EDFGLENTKIIPCESPNESARRLIDVFSGKINEDRNFILMNAGAALYASEIVSDFLEGVEIAKNAIDSGKVLKKLEMIKN
V
>Mature_321_residues
MLNKLVECENLTFEESYELFNMLLEESEIRIAAYLTALQTKGVTADEIAGFAKAMRDNAVKIDLGEVTDTCGTGGDGSKT
INVSTAVSIILACFTKVAKHGNVSVTSKSGSANVYEALGCKILENPDEAKVSIEKTNFAFLFAPKYHPALKKIMPVRSEL
KIKTVFNILGPLANPANPKYQILGVNSPELSEKVANALSKVGGVKKALVINGNGLDELNPNGASKITEYNGKFETYEITP
EDFGLENTKIIPCESPNESARRLIDVFSGKINEDRNFILMNAGAALYASEIVSDFLEGVEIAKNAIDSGKVLKKLEMIKN
V

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=278, Percent_Identity=38.8489208633094, Blast_Score=182, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6320561, Length=320, Percent_Identity=33.4375, Blast_Score=142, Evalue=1e-34,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_METVS (A6UP19)

Other databases:

- EMBL:   CP000742
- RefSeq:   YP_001322853.1
- ProteinModelPortal:   A6UP19
- SMR:   A6UP19
- STRING:   A6UP19
- GeneID:   5325921
- GenomeReviews:   CP000742_GR
- KEGG:   mvn:Mevan_0332
- eggNOG:   arNOG05391
- HOGENOM:   HBG559996
- OMA:   HGNKSAS
- ProtClustDB:   PRK00188
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 34735; Mature: 34735

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNKLVECENLTFEESYELFNMLLEESEIRIAAYLTALQTKGVTADEIAGFAKAMRDNAV
CCCCHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCE
KIDLGEVTDTCGTGGDGSKTINVSTAVSIILACFTKVAKHGNVSVTSKSGSANVYEALGC
EEECCCHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHCC
KILENPDEAKVSIEKTNFAFLFAPKYHPALKKIMPVRSELKIKTVFNILGPLANPANPKY
EEECCCCCCEEEEEECCEEEEECCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCE
QILGVNSPELSEKVANALSKVGGVKKALVINGNGLDELNPNGASKITEYNGKFETYEITP
EEEECCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHEECCCCEEEEEECH
EDFGLENTKIIPCESPNESARRLIDVFSGKINEDRNFILMNAGAALYASEIVSDFLEGVE
HHCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHH
IAKNAIDSGKVLKKLEMIKNV
HHHHHCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MLNKLVECENLTFEESYELFNMLLEESEIRIAAYLTALQTKGVTADEIAGFAKAMRDNAV
CCCCHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCE
KIDLGEVTDTCGTGGDGSKTINVSTAVSIILACFTKVAKHGNVSVTSKSGSANVYEALGC
EEECCCHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHCC
KILENPDEAKVSIEKTNFAFLFAPKYHPALKKIMPVRSELKIKTVFNILGPLANPANPKY
EEECCCCCCEEEEEECCEEEEECCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCE
QILGVNSPELSEKVANALSKVGGVKKALVINGNGLDELNPNGASKITEYNGKFETYEITP
EEEECCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHEECCCCEEEEEECH
EDFGLENTKIIPCESPNESARRLIDVFSGKINEDRNFILMNAGAALYASEIVSDFLEGVE
HHCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHH
IAKNAIDSGKVLKKLEMIKNV
HHHHHCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA