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The map label for this gene is phoR [H]

Identifier: 150398898

GI number: 150398898

Start: 161722

End: 162987

Strand: Reverse

Name: phoR [H]

Synonym: Mevan_0142

Alternate gene names: 150398898

Gene position: 162987-161722 (Counterclockwise)

Preceding gene: 150398899

Following gene: 150398896

Centisome position: 9.48

GC content: 29.62

Gene sequence:

>1266_bases
ATGCACTCTGATAACGAAATATCACTTCGAGATAAAATTATTGGATTAGGAGAACGTTCAGCTAAAAAAAGCTACTATCC
TCAGTTACAGGAAAAATTAAAGTACCTTGAAGAAAAATCCATTGCACTTTTAAATATTTTAGAAGATTTAGAGGATTCTG
AAAAAGAATTAAGGGAAAGTGAAGCACTATTACAAATTGCTGGAAGAACTGCAAAATTTGGAGGATTTAGTGCAGACATT
GGTGAACAAAAAATTACGCTATCTAAACAGGCGGCTTTAATTTTTGAAATGCCGGAAAATTATTCACCATTAATAGATGA
GTTAATAGATTGCTATGATACAAAATACCAAAATATAGCAAAAGAACTTTTTTTTAACTGTGGAATAAATGGTACCCCAT
ATGACATTGAAGTTGAACTTATAACTAAAAATGGGAAAAAAATATGGGTTAGAACAACTGGCGAAGCAGTAAAAAACAGT
AAGAGAAATATTGTCAACGTATATGGGGCATTTCAAGACATTACTGAACAAAAACTTGCTGAACAAAAACTAAAAAAATC
TTATGATGAATTAAAGGAGTTAGATAGATTAAAGTCTGAATTTACTGCAATAATTTCCCACGAAATTAGAACGCCGATAA
CATCAATTAAAGGCTACACTGAATTATTAAATGATGAAAGCATGGGGAAACTTAATAATAATCAAAAAATGTGTTTAAAT
ACGATTTTAGAAAACGTTATAAGGCTTGGAAGACTAGTTTCAGACGTTTTAGACATTTCAAGAATAGAAAGAAATACATT
TACATTGAATATTCAAAAAGTAGATGTTAAAGACGTATTAGAGCATGTTTTAAGTGAATTAGCACCGATAGCTTTAAAAA
AACATATCAAATTGTCACTTGAAATACCTAATATCACTATCGATGCAGATAAGGATAGGTTAAATCAAGTCTTTACAAAC
ATTACCGAAAATGCAATAAAATTTAGTCCTGAAAATGAAAAAGTAGAAATTACTGGAAAAGAAGGATTAAATAGTGATAT
CCTAATAAGTATTAAGGATAATGGGATAGGAATTTCAAAAAACGAGTTTGAAAAGATATTTGATAGATTTTATCAAATTG
ATTCGTCAAATAGGCGGAAAAAAGGAGGAGCTGGATTAGGGCTTCCAATTTCTAAGGGGATTATTAAAGCACATAATGGA
AAAATATGGGTTGAAAGTGAACTTAATCAAGGAAGTACATTTTATATAAGTTTACCAAAAAAATAG

Upstream 100 bases:

>100_bases
AAGGAAATTCCATCACTTTCAATAAATGCCTTTAATGACCCGTGTATTGTAACTAATCCTAGAACTGCTACTTTAAATGA
TATTGAAATGGTGTATAAAA

Downstream 100 bases:

>100_bases
TTTAAAAAGCATTCTTTTTTTCGAGTTAATTTTTTAGAGCTTCCATTATTAAATCTAAATGTTTCAATAATATTTAATTA
GTAACGTATCTAATTACTCT

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MHSDNEISLRDKIIGLGERSAKKSYYPQLQEKLKYLEEKSIALLNILEDLEDSEKELRESEALLQIAGRTAKFGGFSADI
GEQKITLSKQAALIFEMPENYSPLIDELIDCYDTKYQNIAKELFFNCGINGTPYDIEVELITKNGKKIWVRTTGEAVKNS
KRNIVNVYGAFQDITEQKLAEQKLKKSYDELKELDRLKSEFTAIISHEIRTPITSIKGYTELLNDESMGKLNNNQKMCLN
TILENVIRLGRLVSDVLDISRIERNTFTLNIQKVDVKDVLEHVLSELAPIALKKHIKLSLEIPNITIDADKDRLNQVFTN
ITENAIKFSPENEKVEITGKEGLNSDILISIKDNGIGISKNEFEKIFDRFYQIDSSNRRKKGGAGLGLPISKGIIKAHNG
KIWVESELNQGSTFYISLPKK

Sequences:

>Translated_421_residues
MHSDNEISLRDKIIGLGERSAKKSYYPQLQEKLKYLEEKSIALLNILEDLEDSEKELRESEALLQIAGRTAKFGGFSADI
GEQKITLSKQAALIFEMPENYSPLIDELIDCYDTKYQNIAKELFFNCGINGTPYDIEVELITKNGKKIWVRTTGEAVKNS
KRNIVNVYGAFQDITEQKLAEQKLKKSYDELKELDRLKSEFTAIISHEIRTPITSIKGYTELLNDESMGKLNNNQKMCLN
TILENVIRLGRLVSDVLDISRIERNTFTLNIQKVDVKDVLEHVLSELAPIALKKHIKLSLEIPNITIDADKDRLNQVFTN
ITENAIKFSPENEKVEITGKEGLNSDILISIKDNGIGISKNEFEKIFDRFYQIDSSNRRKKGGAGLGLPISKGIIKAHNG
KIWVESELNQGSTFYISLPKK
>Mature_421_residues
MHSDNEISLRDKIIGLGERSAKKSYYPQLQEKLKYLEEKSIALLNILEDLEDSEKELRESEALLQIAGRTAKFGGFSADI
GEQKITLSKQAALIFEMPENYSPLIDELIDCYDTKYQNIAKELFFNCGINGTPYDIEVELITKNGKKIWVRTTGEAVKNS
KRNIVNVYGAFQDITEQKLAEQKLKKSYDELKELDRLKSEFTAIISHEIRTPITSIKGYTELLNDESMGKLNNNQKMCLN
TILENVIRLGRLVSDVLDISRIERNTFTLNIQKVDVKDVLEHVLSELAPIALKKHIKLSLEIPNITIDADKDRLNQVFTN
ITENAIKFSPENEKVEITGKEGLNSDILISIKDNGIGISKNEFEKIFDRFYQIDSSNRRKKGGAGLGLPISKGIIKAHNG
KIWVESELNQGSTFYISLPKK

Specific function: Member of the two-component regulatory system phoP/phoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates phoP in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=260, Percent_Identity=33.4615384615385, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1789149, Length=235, Percent_Identity=36.1702127659575, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI1786600, Length=240, Percent_Identity=29.1666666666667, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI145693157, Length=294, Percent_Identity=27.891156462585, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1788713, Length=264, Percent_Identity=34.0909090909091, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1788549, Length=344, Percent_Identity=26.7441860465116, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1788393, Length=242, Percent_Identity=27.2727272727273, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1786783, Length=222, Percent_Identity=28.3783783783784, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1786912, Length=230, Percent_Identity=28.695652173913, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1790436, Length=237, Percent_Identity=29.957805907173, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI87081816, Length=242, Percent_Identity=29.3388429752066, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1788279, Length=249, Percent_Identity=32.5301204819277, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI87082128, Length=253, Percent_Identity=25.6916996047431, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790346, Length=208, Percent_Identity=30.2884615384615, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790861, Length=208, Percent_Identity=26.9230769230769, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787894, Length=273, Percent_Identity=23.4432234432234, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790551, Length=224, Percent_Identity=25, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789403, Length=202, Percent_Identity=28.2178217821782, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787374, Length=214, Percent_Identity=25.2336448598131, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 47748; Mature: 47748

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSDNEISLRDKIIGLGERSAKKSYYPQLQEKLKYLEEKSIALLNILEDLEDSEKELRES
CCCCCCEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EALLQIAGRTAKFGGFSADIGEQKITLSKQAALIFEMPENYSPLIDELIDCYDTKYQNIA
HHHHHHHCCCCCCCCCCCCCCCCEEEEECCEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
KELFFNCGINGTPYDIEVELITKNGKKIWVRTTGEAVKNSKRNIVNVYGAFQDITEQKLA
HHHHHHCCCCCCCCEEEEEEEECCCCEEEEEECCHHHHCCCCCEEEHHHHHHHHHHHHHH
EQKLKKSYDELKELDRLKSEFTAIISHEIRTPITSIKGYTELLNDESMGKLNNNQKMCLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHHHH
TILENVIRLGRLVSDVLDISRIERNTFTLNIQKVDVKDVLEHVLSELAPIALKKHIKLSL
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHCEEEEE
EIPNITIDADKDRLNQVFTNITENAIKFSPENEKVEITGKEGLNSDILISIKDNGIGISK
ECCEEEEECCHHHHHHHHHHHHHHHEEECCCCCEEEEECCCCCCCCEEEEECCCCCCCCH
NEFEKIFDRFYQIDSSNRRKKGGAGLGLPISKGIIKAHNGKIWVESELNQGSTFYISLPK
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCEEEECCCEEEEEECCCCCCEEEEECCC
K
C
>Mature Secondary Structure
MHSDNEISLRDKIIGLGERSAKKSYYPQLQEKLKYLEEKSIALLNILEDLEDSEKELRES
CCCCCCEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EALLQIAGRTAKFGGFSADIGEQKITLSKQAALIFEMPENYSPLIDELIDCYDTKYQNIA
HHHHHHHCCCCCCCCCCCCCCCCEEEEECCEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
KELFFNCGINGTPYDIEVELITKNGKKIWVRTTGEAVKNSKRNIVNVYGAFQDITEQKLA
HHHHHHCCCCCCCCEEEEEEEECCCCEEEEEECCHHHHCCCCCEEEHHHHHHHHHHHHHH
EQKLKKSYDELKELDRLKSEFTAIISHEIRTPITSIKGYTELLNDESMGKLNNNQKMCLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHHHH
TILENVIRLGRLVSDVLDISRIERNTFTLNIQKVDVKDVLEHVLSELAPIALKKHIKLSL
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHCEEEEE
EIPNITIDADKDRLNQVFTNITENAIKFSPENEKVEITGKEGLNSDILISIKDNGIGISK
ECCEEEEECCHHHHHHHHHHHHHHHEEECCCCCEEEEECCCCCCCCEEEEECCCCCCCCH
NEFEKIFDRFYQIDSSNRRKKGGAGLGLPISKGIIKAHNGKIWVESELNQGSTFYISLPK
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCEEEECCCEEEEEECCCCCCEEEEECCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3142862; 9387221; 9384377 [H]