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The map label for this gene is 150398497

Identifier: 150398497

GI number: 150398497

Start: 3498596

End: 3500617

Strand: Reverse

Name: 150398497

Synonym: Smed_3307

Alternate gene names: NA

Gene position: 3500617-3498596 (Counterclockwise)

Preceding gene: 150398498

Following gene: 150398496

Centisome position: 92.56

GC content: 63.11

Gene sequence:

>2022_bases
ATGGCAACGCGTATTGGTGTCGACATTGGCGGCACGTTCACCGATCTCGTCTATTTCGACGAGCGGACCGGCAAAACGGT
TGAAGGAAAGGTTCCGACCGTGCCTTCGGCGCCGGAGGAGGGGGTGGTCAATGCGATCACCCAGCACGTCCCGCAGGAGA
TTATCGAGGAAGCGCTGTTCTTTCTGCACGGGACGACCGTAGGCCTCAACGCTCTTCTCGAGCGGCGCGGCTCCAGGATC
GGCCTGATCACCACGACGGGTTTCCGCGACGTGCTGGAAATCCGCCGAGGCGACCGGGTGGAAATGTATAATCTGTTCTG
GAAGCAGACGGAGCCGCTGGTGCCACGTCGCCTGCGCCTCGAAGTCGATGGCCGCATGCTGGGCAATGGCCGCGAGTATC
GCCCGCTCGACGCCGACACCGTGAAAGCGGCGGCGCAAAAGATGATTGCGGAAAGCGTCGATGCCATCGCGGTCAGTCTG
ATCAACGCCTACGCCAATCCCGCCCACGAGCTCGAAGTCGAGCGGCTGTTGCGTGAGGAAGGCTTTGAAGGCGGTATCTC
GCTGTCCCACAGGATCTCGGGCGAGTATCGCGAGTATGAGCGCACTTCGACCACCTGCATCGATGCTTTCGTGCGTGGCC
GGATGTCGAACTACTTGCGCCGTCTCGACGGCCGCCTGCGCGAGATGGGCTTTAAGGGCACATCGCTGATCACCCGCTCC
GGTTCGGGTTCGATGACCTTCGCCGAGGCCGAGGACCGCCCGTTCGAAACCATCATGTCGGGACCGGTCGGCGGCGCGCA
AGGGGCGAGCGAACTCGCCAAGATGCTCGGCATCAAGGCCCTGGTCACCGCCGATGTCGGCGGCACCAGCTTCGACACCG
CTCTGGTGATCGACGGCAAGCCGCAGATCCTGTTCGAGGGCATGATCGACAATATGCCGATCCAGAGTCCCTGGGTCGAT
GTGCGCTCCATCGGTTCGGGAGGCGGCTCGATCGCCCATATCGATCCCGGTGGTCTGATGCGGGTCGGACCGCGTTCTGC
GCAGGCCGTCCCGGGGCCGGCCTGTTACGGCAAGGGCGGCACCGAACCCGCCATGACCGATGCGGCCGCATGGCTCGGTA
TGCTCGGGCCAGGCGATCTCGCCTCCGGCATTCACCTCAATATTGAAAAAGCGCGTGCAGCGCTTGAGTCGGTCGGCACC
CATATCGGTCAGGACGTCGAGGCGACGGCAGCGGGCGTCATGCGAATCTCATCGGCGGCAATGGCCAATGCCATGCGCGA
AATCTCGCTCGATCAGGGCCTCGATCCACGCACGATCACGCTTCTTCCCTTCGGCGGCGCCGGCCCGTTGATGGGGACGT
TGCTGGCCGACGAGCTTGAAATGAACCATGTCATCATCCCGCCGCTGGCGGGCAATTTCTCCGCATGGGGCCTGTTGGGC
GCCGACATGGTGCAATCGACGGCGCGCACGCGGGTTATCGGCTTTGCTCCCGGCGCCCTGACCGAGGTCGCCCGAATTCT
GGAAGAGCTGTTCGCAACATTGACGGAACGCAGCACGGCGCATGCCGGCGACGGCGTGCGCTCCGTACGTCTCGACCTGC
GCTACAAGGGTCAGGAGCATACTCTGTCCATCGAAGTCGAACTGGCCGAAGGACGTATTGCCGAAACCGAGGAGGCTATC
CTCGAGCGTTTCGTGGCCGAGTATGCCCGCACGTTCGGCTCGACGATGAACGAGGATGTCGAACTGGTCTCGGTCCGTGC
CAGCACCACGGTGCTCTTGCCGCGCCGGGAGCTGAGCTACACGTCCAAGCGCTCGGATGGCGAAGATGATAGGGTTATGG
AGGTCTATTCCTTCGAATCCAGGGCGCGACTGCCCTTCCGGATCATCCCCCGTGGCCGGATTTCCGGCGAGATCCGCGGC
CCCGCCATCATCACCGAAGACACGACGACCACCTATGTCGATGTCCAGTGGACCATCTCGAGCGGCAAAGCCGGCGAAAT
CATTTTGGAACGGACGCACTGA

Upstream 100 bases:

>100_bases
GCCGGTCGTCGTTCTCTCCGATGCCGTGACCAAGTTCACCTTCTCGCCGCTCCCCGACTATCGCTACTGGGCGAAATAAA
CTCTCCGGAGGAAAGAAAGA

Downstream 100 bases:

>100_bases
AATGGCTAGAAAACATGAATCCGTCACCCATAATGCCGGCATGTTCGGCCGCATCACCGATGCCAAGGCCGACCCGATCA
CCACCGAGGTCATTCGCCAC

Product: 5-oxoprolinase

Products: ADP; phosphate; N-carbamoylsarcosine

Alternate protein names: NA

Number of amino acids: Translated: 673; Mature: 672

Protein sequence:

>673_residues
MATRIGVDIGGTFTDLVYFDERTGKTVEGKVPTVPSAPEEGVVNAITQHVPQEIIEEALFFLHGTTVGLNALLERRGSRI
GLITTTGFRDVLEIRRGDRVEMYNLFWKQTEPLVPRRLRLEVDGRMLGNGREYRPLDADTVKAAAQKMIAESVDAIAVSL
INAYANPAHELEVERLLREEGFEGGISLSHRISGEYREYERTSTTCIDAFVRGRMSNYLRRLDGRLREMGFKGTSLITRS
GSGSMTFAEAEDRPFETIMSGPVGGAQGASELAKMLGIKALVTADVGGTSFDTALVIDGKPQILFEGMIDNMPIQSPWVD
VRSIGSGGGSIAHIDPGGLMRVGPRSAQAVPGPACYGKGGTEPAMTDAAAWLGMLGPGDLASGIHLNIEKARAALESVGT
HIGQDVEATAAGVMRISSAAMANAMREISLDQGLDPRTITLLPFGGAGPLMGTLLADELEMNHVIIPPLAGNFSAWGLLG
ADMVQSTARTRVIGFAPGALTEVARILEELFATLTERSTAHAGDGVRSVRLDLRYKGQEHTLSIEVELAEGRIAETEEAI
LERFVAEYARTFGSTMNEDVELVSVRASTTVLLPRRELSYTSKRSDGEDDRVMEVYSFESRARLPFRIIPRGRISGEIRG
PAIITEDTTTTYVDVQWTISSGKAGEIILERTH

Sequences:

>Translated_673_residues
MATRIGVDIGGTFTDLVYFDERTGKTVEGKVPTVPSAPEEGVVNAITQHVPQEIIEEALFFLHGTTVGLNALLERRGSRI
GLITTTGFRDVLEIRRGDRVEMYNLFWKQTEPLVPRRLRLEVDGRMLGNGREYRPLDADTVKAAAQKMIAESVDAIAVSL
INAYANPAHELEVERLLREEGFEGGISLSHRISGEYREYERTSTTCIDAFVRGRMSNYLRRLDGRLREMGFKGTSLITRS
GSGSMTFAEAEDRPFETIMSGPVGGAQGASELAKMLGIKALVTADVGGTSFDTALVIDGKPQILFEGMIDNMPIQSPWVD
VRSIGSGGGSIAHIDPGGLMRVGPRSAQAVPGPACYGKGGTEPAMTDAAAWLGMLGPGDLASGIHLNIEKARAALESVGT
HIGQDVEATAAGVMRISSAAMANAMREISLDQGLDPRTITLLPFGGAGPLMGTLLADELEMNHVIIPPLAGNFSAWGLLG
ADMVQSTARTRVIGFAPGALTEVARILEELFATLTERSTAHAGDGVRSVRLDLRYKGQEHTLSIEVELAEGRIAETEEAI
LERFVAEYARTFGSTMNEDVELVSVRASTTVLLPRRELSYTSKRSDGEDDRVMEVYSFESRARLPFRIIPRGRISGEIRG
PAIITEDTTTTYVDVQWTISSGKAGEIILERTH
>Mature_672_residues
ATRIGVDIGGTFTDLVYFDERTGKTVEGKVPTVPSAPEEGVVNAITQHVPQEIIEEALFFLHGTTVGLNALLERRGSRIG
LITTTGFRDVLEIRRGDRVEMYNLFWKQTEPLVPRRLRLEVDGRMLGNGREYRPLDADTVKAAAQKMIAESVDAIAVSLI
NAYANPAHELEVERLLREEGFEGGISLSHRISGEYREYERTSTTCIDAFVRGRMSNYLRRLDGRLREMGFKGTSLITRSG
SGSMTFAEAEDRPFETIMSGPVGGAQGASELAKMLGIKALVTADVGGTSFDTALVIDGKPQILFEGMIDNMPIQSPWVDV
RSIGSGGGSIAHIDPGGLMRVGPRSAQAVPGPACYGKGGTEPAMTDAAAWLGMLGPGDLASGIHLNIEKARAALESVGTH
IGQDVEATAAGVMRISSAAMANAMREISLDQGLDPRTITLLPFGGAGPLMGTLLADELEMNHVIIPPLAGNFSAWGLLGA
DMVQSTARTRVIGFAPGALTEVARILEELFATLTERSTAHAGDGVRSVRLDLRYKGQEHTLSIEVELAEGRIAETEEAIL
ERFVAEYARTFGSTMNEDVELVSVRASTTVLLPRRELSYTSKRSDGEDDRVMEVYSFESRARLPFRIIPRGRISGEIRGP
AIITEDTTTTYVDVQWTISSGKAGEIILERTH

Specific function: Unknown

COG id: COG0145

COG function: function code EQ; N-methylhydantoinase A/acetone carboxylase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

Organism=Homo sapiens, GI48314820, Length=733, Percent_Identity=27.5579809004093, Blast_Score=174, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI133901900, Length=385, Percent_Identity=28.3116883116883, Blast_Score=122, Evalue=7e-28,
Organism=Saccharomyces cerevisiae, GI6322634, Length=728, Percent_Identity=27.8846153846154, Blast_Score=186, Evalue=1e-47,
Organism=Drosophila melanogaster, GI45550492, Length=733, Percent_Identity=25.9208731241473, Blast_Score=182, Evalue=7e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008040
- InterPro:   IPR002821 [H]

Pfam domain/function: PF05378 Hydant_A_N; PF01968 Hydantoinase_A [H]

EC number: 3.5.2.14

Molecular weight: Translated: 72825; Mature: 72694

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATRIGVDIGGTFTDLVYFDERTGKTVEGKVPTVPSAPEEGVVNAITQHVPQEIIEEALF
CCEEEEEECCCCEEEEEEEECCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
FLHGTTVGLNALLERRGSRIGLITTTGFRDVLEIRRGDRVEMYNLFWKQTEPLVPRRLRL
HHCCCHHHHHHHHHHCCCEEEEEEECCHHHHHHHHCCCCEEEHHHHHHCCCCCCCCEEEE
EVDGRMLGNGREYRPLDADTVKAAAQKMIAESVDAIAVSLINAYANPAHELEVERLLREE
EECCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
GFEGGISLSHRISGEYREYERTSTTCIDAFVRGRMSNYLRRLDGRLREMGFKGTSLITRS
CCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
GSGSMTFAEAEDRPFETIMSGPVGGAQGASELAKMLGIKALVTADVGGTSFDTALVIDGK
CCCCEEEECCCCCCHHHHHCCCCCCCCCHHHHHHHHCCEEEEEECCCCCCCCEEEEECCC
PQILFEGMIDNMPIQSPWVDVRSIGSGGGSIAHIDPGGLMRVGPRSAQAVPGPACYGKGG
CCEEEECHHCCCCCCCCCCHHHHCCCCCCEEEEECCCCCEEECCCCCCCCCCCCCCCCCC
TEPAMTDAAAWLGMLGPGDLASGIHLNIEKARAALESVGTHIGQDVEATAAGVMRISSAA
CCCHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
MANAMREISLDQGLDPRTITLLPFGGAGPLMGTLLADELEMNHVIIPPLAGNFSAWGLLG
HHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHH
ADMVQSTARTRVIGFAPGALTEVARILEELFATLTERSTAHAGDGVRSVRLDLRYKGQEH
HHHHHHHHHCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCE
TLSIEVELAEGRIAETEEAILERFVAEYARTFGSTMNEDVELVSVRASTTVLLPRRELSY
EEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCEEEEECCHHHCC
TSKRSDGEDDRVMEVYSFESRARLPFRIIPRGRISGEIRGPAIITEDTTTTYVDVQWTIS
CCCCCCCCCCCEEEEEECCCCCCCCEEEECCCCCCCCCCCCEEEECCCCEEEEEEEEEEC
SGKAGEIILERTH
CCCCCEEEEEECC
>Mature Secondary Structure 
ATRIGVDIGGTFTDLVYFDERTGKTVEGKVPTVPSAPEEGVVNAITQHVPQEIIEEALF
CEEEEEECCCCEEEEEEEECCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
FLHGTTVGLNALLERRGSRIGLITTTGFRDVLEIRRGDRVEMYNLFWKQTEPLVPRRLRL
HHCCCHHHHHHHHHHCCCEEEEEEECCHHHHHHHHCCCCEEEHHHHHHCCCCCCCCEEEE
EVDGRMLGNGREYRPLDADTVKAAAQKMIAESVDAIAVSLINAYANPAHELEVERLLREE
EECCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
GFEGGISLSHRISGEYREYERTSTTCIDAFVRGRMSNYLRRLDGRLREMGFKGTSLITRS
CCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
GSGSMTFAEAEDRPFETIMSGPVGGAQGASELAKMLGIKALVTADVGGTSFDTALVIDGK
CCCCEEEECCCCCCHHHHHCCCCCCCCCHHHHHHHHCCEEEEEECCCCCCCCEEEEECCC
PQILFEGMIDNMPIQSPWVDVRSIGSGGGSIAHIDPGGLMRVGPRSAQAVPGPACYGKGG
CCEEEECHHCCCCCCCCCCHHHHCCCCCCEEEEECCCCCEEECCCCCCCCCCCCCCCCCC
TEPAMTDAAAWLGMLGPGDLASGIHLNIEKARAALESVGTHIGQDVEATAAGVMRISSAA
CCCHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
MANAMREISLDQGLDPRTITLLPFGGAGPLMGTLLADELEMNHVIIPPLAGNFSAWGLLG
HHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHH
ADMVQSTARTRVIGFAPGALTEVARILEELFATLTERSTAHAGDGVRSVRLDLRYKGQEH
HHHHHHHHHCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCE
TLSIEVELAEGRIAETEEAILERFVAEYARTFGSTMNEDVELVSVRASTTVLLPRRELSY
EEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCEEEEECCHHHCC
TSKRSDGEDDRVMEVYSFESRARLPFRIIPRGRISGEIRGPAIITEDTTTTYVDVQWTIS
CCCCCCCCCCCEEEEEECCCCCCCCEEEECCCCCCCCCCCCEEEECCCCEEEEEEEEEEC
SGKAGEIILERTH
CCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; N-methylimidazolidine-2,4-dione; H2O

Specific reaction: ATP + N-methylimidazolidine-2,4-dione + 2 H2O = ADP + phosphate + N-carbamoylsarcosine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]