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The map label for this gene is htpX [H]

Identifier: 150398384

GI number: 150398384

Start: 3363794

End: 3364753

Strand: Reverse

Name: htpX [H]

Synonym: Smed_3192

Alternate gene names: 150398384

Gene position: 3364753-3363794 (Counterclockwise)

Preceding gene: 150398386

Following gene: 150398383

Centisome position: 88.97

GC content: 62.81

Gene sequence:

>960_bases
ATGAATCTCATGCGCACCGCAATGCTGCTAGCCTTCATGACCGTCCTGTTCATGGCCGTCGGCTATGTGATCGGCGGCCG
GGGTGGCATGATGATCGCCCTCGTCATTGCCGCGGGCATGAATTTCTTCTCCTATTGGAATTCCGATCGGATGGTGCTGC
GGATGTACCGGGCGCAGGAGGTCGATGAGCGAAGCGCCCCGGAATATTACGGCATCGTGCGTGACCTCGCAAAGAATGCC
GGCCTGCCGATGCCGCGCGTCTATGTCATCGACAGTCCCCAGCCGAACGCATTCGCCACCGGGCGCAATCCCGAAAACGC
CGCGGTCGCCGCTTCGACGGGACTGCTGCATTCGCTCTCCTACGAGGAGGTCGCCGGGGTGATGGCGCACGAGCTTGCCC
ATATCCAGTACCGCGATACCCTGACGATGACGATGACGGCAACGCTTGCCGGTGCGATTTCCATGCTCGGCAACTTTGCC
TTCTTTTTCGGCGGAAACCGCGAGAACAACAATCCGCTCGGCTTTATCGGCGTGCTGATCGCGATGATCGTCGCTCCGCT
GGCGGCGGCGCTCGTGCAGATGGCGATCAGCCGCACCCGCGAATATTCCGCCGACCGGCGCGGCGCGGAGATCTGCGGCA
ACCCGCTCTGGCTTTCCTCGGCGCTCCGCAAGATCGCCGGAGCGGCGCATGTCGTTCACAATCCCGATGCCGAGCGCAAT
CCTGCGACCGCGCATATGTTCATCATCAATCCCCTCTCGGGCGAGCGGATGGACAATCTGTTCTCGACCCATCCCAACAC
CGAGAACCGGGTCGTGGCCCTCGAGAGAATGGCCCGGGAGATGTCCACGGGGTCGACGGCACCCGTTCGGCCTGATAATG
CGGTGCGAAAATCGCGCTCTGTCCCGAGAACCGGCTGGGGTCGCGGTGGTTCCGAACCGCCGAAAGGCCCCTGGTCCTGA

Upstream 100 bases:

>100_bases
GATTCACGTGAAACCCTCGCACAGGGCTGATGGAGCGATGCGGCCGCAGGCGGCTTTCCACAGAGTGCGGAACGGATCAC
GAACTGGTTGGAGCTCATTC

Downstream 100 bases:

>100_bases
TGCCCGAAGACAGCAAGAACGATTCTCATCCGAAACGAATCCGAGAACACAGGCGCCCCGGATTGGGAGGGCCCAAGGCC
GGCGCGCTTGCCCCGGCCAA

Product: heat shock protein HtpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MNLMRTAMLLAFMTVLFMAVGYVIGGRGGMMIALVIAAGMNFFSYWNSDRMVLRMYRAQEVDERSAPEYYGIVRDLAKNA
GLPMPRVYVIDSPQPNAFATGRNPENAAVAASTGLLHSLSYEEVAGVMAHELAHIQYRDTLTMTMTATLAGAISMLGNFA
FFFGGNRENNNPLGFIGVLIAMIVAPLAAALVQMAISRTREYSADRRGAEICGNPLWLSSALRKIAGAAHVVHNPDAERN
PATAHMFIINPLSGERMDNLFSTHPNTENRVVALERMAREMSTGSTAPVRPDNAVRKSRSVPRTGWGRGGSEPPKGPWS

Sequences:

>Translated_319_residues
MNLMRTAMLLAFMTVLFMAVGYVIGGRGGMMIALVIAAGMNFFSYWNSDRMVLRMYRAQEVDERSAPEYYGIVRDLAKNA
GLPMPRVYVIDSPQPNAFATGRNPENAAVAASTGLLHSLSYEEVAGVMAHELAHIQYRDTLTMTMTATLAGAISMLGNFA
FFFGGNRENNNPLGFIGVLIAMIVAPLAAALVQMAISRTREYSADRRGAEICGNPLWLSSALRKIAGAAHVVHNPDAERN
PATAHMFIINPLSGERMDNLFSTHPNTENRVVALERMAREMSTGSTAPVRPDNAVRKSRSVPRTGWGRGGSEPPKGPWS
>Mature_319_residues
MNLMRTAMLLAFMTVLFMAVGYVIGGRGGMMIALVIAAGMNFFSYWNSDRMVLRMYRAQEVDERSAPEYYGIVRDLAKNA
GLPMPRVYVIDSPQPNAFATGRNPENAAVAASTGLLHSLSYEEVAGVMAHELAHIQYRDTLTMTMTATLAGAISMLGNFA
FFFGGNRENNNPLGFIGVLIAMIVAPLAAALVQMAISRTREYSADRRGAEICGNPLWLSSALRKIAGAAHVVHNPDAERN
PATAHMFIINPLSGERMDNLFSTHPNTENRVVALERMAREMSTGSTAPVRPDNAVRKSRSVPRTGWGRGGSEPPKGPWS

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=298, Percent_Identity=30.8724832214765, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 34724; Mature: 34724

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
6.6 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
6.6 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLMRTAMLLAFMTVLFMAVGYVIGGRGGMMIALVIAAGMNFFSYWNSDRMVLRMYRAQE
CCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
VDERSAPEYYGIVRDLAKNAGLPMPRVYVIDSPQPNAFATGRNPENAAVAASTGLLHSLS
HHHCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEECCCCCCCCEEEHHHHHHHHCC
YEEVAGVMAHELAHIQYRDTLTMTMTATLAGAISMLGNFAFFFGGNRENNNPLGFIGVLI
HHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHH
AMIVAPLAAALVQMAISRTREYSADRRGAEICGNPLWLSSALRKIAGAAHVVHNPDAERN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
PATAHMFIINPLSGERMDNLFSTHPNTENRVVALERMAREMSTGSTAPVRPDNAVRKSRS
CCEEEEEEEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCC
VPRTGWGRGGSEPPKGPWS
CCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNLMRTAMLLAFMTVLFMAVGYVIGGRGGMMIALVIAAGMNFFSYWNSDRMVLRMYRAQE
CCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
VDERSAPEYYGIVRDLAKNAGLPMPRVYVIDSPQPNAFATGRNPENAAVAASTGLLHSLS
HHHCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEECCCCCCCCEEEHHHHHHHHCC
YEEVAGVMAHELAHIQYRDTLTMTMTATLAGAISMLGNFAFFFGGNRENNNPLGFIGVLI
HHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHH
AMIVAPLAAALVQMAISRTREYSADRRGAEICGNPLWLSSALRKIAGAAHVVHNPDAERN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
PATAHMFIINPLSGERMDNLFSTHPNTENRVVALERMAREMSTGSTAPVRPDNAVRKSRS
CCEEEEEEEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCC
VPRTGWGRGGSEPPKGPWS
CCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]