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The map label for this gene is deoR [H]

Identifier: 150398325

GI number: 150398325

Start: 3280545

End: 3281495

Strand: Direct

Name: deoR [H]

Synonym: Smed_3131

Alternate gene names: 150398325

Gene position: 3280545-3281495 (Clockwise)

Preceding gene: 150398324

Following gene: 150398326

Centisome position: 86.74

GC content: 62.67

Gene sequence:

>951_bases
ATGGGACGGCTCAACGAGCTTCGACTGATCGCCCGCGTAGCCCAGATGTACCATATCGAAAGCAAGAGGCAGGCCGAGAT
CGCCGAAATCATGCACATGTCGCAGGCAACCGTTTCCCGCATGCTGAAGCGCGCCGAGCAGGAAGACATCGTGCGCACCA
CGGTCATTCCCCCCGCCGGTACCTTTGCGGATCTCGAAACTGCATTGCGCGAGCGCTATGGCCTGACCGAAGCGATCGTC
ATCGACTGTTCGGAAGATCGCGATGGAGCGATCATGGCGCGCATCGGCGAGGCGGCTGCCCATTTCCTCGAAGTCACGCT
GCAGCAGGACGAGATCGTCGGGGTATCGAGCTGGAGTCAGACCATTCTGCGCATGGTGGACAACATCCACCCGCTGAAGA
ACGCCAAGGCGAAGTACATCGTGCAGATCCTCGGCGGCATGGGCGACGCCTCGGTGCAGACCCATGCCACGCAGCTGACC
GCGCGCCTTGCAAGACTCACCGGCGGCGAGCCGCGATTGCTTCTCGTTCAGGGGATCACCTCCTCACGCGAGGCGAAACT
CGTCATGCTCGCCGACCCGGTGGTGCGCGAGACGATGGACCTCTTCGGCCGCCTCAGCCTTGCGATCATCGGCATTGGCG
CGGTGGAACCATCGGAACTGCTCGCCCGCTCCGGCAACACCTTCTCCCGCCAGGAAATGGCGATGTTGCACGAGGCCGGG
GCGGTCGGCGAGATTTCCTACCGATTCTACGACAAGGGCGGAAAGCCGGTCGAAACCCCGCTTAACGACCGCGTAATCGG
CATCTCGCTGGAAGACCTGCGCAAGACCGGCCGCGTCATGGCGCTCGCGGGCGGCGAATCCAAAACCCAAGCCATTGCCG
GCGCCCTTAGACTTGGCGTTATCGATGTGCTCGTCACCGACAAGTTCACAGCAGCTCGGCTCACGGCCTGA

Upstream 100 bases:

>100_bases
CCGCAGATCGCCTCATGGTTTGGCAGGACGCAATCTACCGCTCGACCGTTCCAGGTCCTTCAATTATGAGTGAATAAAAA
TTCACCACTGGAGGATCCCG

Downstream 100 bases:

>100_bases
TCTGAAGATCGGTCCTGGCCCGTTGCGCATTATGGAGGAAAGACCATGAGACGTTTCGCAGGCCAGACGGTTTTCGTCAC
CGGCGGCAACAAGGGAATCG

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MGRLNELRLIARVAQMYHIESKRQAEIAEIMHMSQATVSRMLKRAEQEDIVRTTVIPPAGTFADLETALRERYGLTEAIV
IDCSEDRDGAIMARIGEAAAHFLEVTLQQDEIVGVSSWSQTILRMVDNIHPLKNAKAKYIVQILGGMGDASVQTHATQLT
ARLARLTGGEPRLLLVQGITSSREAKLVMLADPVVRETMDLFGRLSLAIIGIGAVEPSELLARSGNTFSRQEMAMLHEAG
AVGEISYRFYDKGGKPVETPLNDRVIGISLEDLRKTGRVMALAGGESKTQAIAGALRLGVIDVLVTDKFTAARLTA

Sequences:

>Translated_316_residues
MGRLNELRLIARVAQMYHIESKRQAEIAEIMHMSQATVSRMLKRAEQEDIVRTTVIPPAGTFADLETALRERYGLTEAIV
IDCSEDRDGAIMARIGEAAAHFLEVTLQQDEIVGVSSWSQTILRMVDNIHPLKNAKAKYIVQILGGMGDASVQTHATQLT
ARLARLTGGEPRLLLVQGITSSREAKLVMLADPVVRETMDLFGRLSLAIIGIGAVEPSELLARSGNTFSRQEMAMLHEAG
AVGEISYRFYDKGGKPVETPLNDRVIGISLEDLRKTGRVMALAGGESKTQAIAGALRLGVIDVLVTDKFTAARLTA
>Mature_315_residues
GRLNELRLIARVAQMYHIESKRQAEIAEIMHMSQATVSRMLKRAEQEDIVRTTVIPPAGTFADLETALRERYGLTEAIVI
DCSEDRDGAIMARIGEAAAHFLEVTLQQDEIVGVSSWSQTILRMVDNIHPLKNAKAKYIVQILGGMGDASVQTHATQLTA
RLARLTGGEPRLLLVQGITSSREAKLVMLADPVVRETMDLFGRLSLAIIGIGAVEPSELLARSGNTFSRQEMAMLHEAGA
VGEISYRFYDKGGKPVETPLNDRVIGISLEDLRKTGRVMALAGGESKTQAIAGALRLGVIDVLVTDKFTAARLTA

Specific function: Negative regulator of the dra-nupC-pdp operon. DeoR binds cooperatively to the operator DNA, which consists of a palindrome and a direct repeat sequence located 3' to the palindrome [H]

COG id: COG2390

COG function: function code K; Transcriptional regulator, contains sigma factor-related N-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sorC transcriptional regulatory family [H]

Homologues:

Organism=Escherichia coli, GI87082414, Length=311, Percent_Identity=30.5466237942122, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1787791, Length=306, Percent_Identity=28.7581699346405, Blast_Score=102, Evalue=3e-23,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR007630
- InterPro:   IPR007324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04545 Sigma70_r4; PF04198 Sugar-bind [H]

EC number: NA

Molecular weight: Translated: 34404; Mature: 34273

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRLNELRLIARVAQMYHIESKRQAEIAEIMHMSQATVSRMLKRAEQEDIVRTTVIPPAG
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCC
TFADLETALRERYGLTEAIVIDCSEDRDGAIMARIGEAAAHFLEVTLQQDEIVGVSSWSQ
CHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHEECCCCEEEHHHHHH
TILRMVDNIHPLKNAKAKYIVQILGGMGDASVQTHATQLTARLARLTGGEPRLLLVQGIT
HHHHHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
SSREAKLVMLADPVVRETMDLFGRLSLAIIGIGAVEPSELLARSGNTFSRQEMAMLHEAG
CCCCCEEEEECCHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHCCCCCHHHHHHHHHHCC
AVGEISYRFYDKGGKPVETPLNDRVIGISLEDLRKTGRVMALAGGESKTQAIAGALRLGV
CCCEEEEEEECCCCCCCCCCCCCCEEEEEHHHHHHCCCEEEEECCCHHHHHHHHHHHHHH
IDVLVTDKFTAARLTA
HHHEEECCCCHHHCCC
>Mature Secondary Structure 
GRLNELRLIARVAQMYHIESKRQAEIAEIMHMSQATVSRMLKRAEQEDIVRTTVIPPAG
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCC
TFADLETALRERYGLTEAIVIDCSEDRDGAIMARIGEAAAHFLEVTLQQDEIVGVSSWSQ
CHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHEECCCCEEEHHHHHH
TILRMVDNIHPLKNAKAKYIVQILGGMGDASVQTHATQLTARLARLTGGEPRLLLVQGIT
HHHHHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
SSREAKLVMLADPVVRETMDLFGRLSLAIIGIGAVEPSELLARSGNTFSRQEMAMLHEAG
CCCCCEEEEECCHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHCCCCCHHHHHHHHHHCC
AVGEISYRFYDKGGKPVETPLNDRVIGISLEDLRKTGRVMALAGGESKTQAIAGALRLGV
CCCEEEEEEECCCCCCCCCCCCCCEEEEEHHHHHHCCCEEEEECCCHHHHHHHHHHHHHH
IDVLVTDKFTAARLTA
HHHEEECCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8550462; 8867804; 9384377; 10074062; 10714997 [H]