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The map label for this gene is lsrR [H]

Identifier: 150398237

GI number: 150398237

Start: 3192219

End: 3193196

Strand: Direct

Name: lsrR [H]

Synonym: Smed_3043

Alternate gene names: 150398237

Gene position: 3192219-3193196 (Clockwise)

Preceding gene: 150398226

Following gene: 150398238

Centisome position: 84.41

GC content: 61.45

Gene sequence:

>978_bases
ATGTCGGAAGATGATGACGCGCTGATGGTGCGGGCGGCCTGGTTTTACTATGTCGGCGGCCTCAACCAGGAAATGACCGC
CGCCCGGCTGGGCCTCACCCGTGCCAGGGTCAATAAAATGCTGGCCGAGGCGCGCGAGAGCGGGCTTGTCAGCATTTCGA
TCGACCATCGGCGGGTCGGTGTCCTGCCGCTCGAGGACAGGCTGCGCACGCGCTTCGGGCTTGATTTCTGCATCTCCACA
CCGGCCTTCGGGTTTCACGATACGTCCAAGCAAGACAGCGAAGTGCGCAAGCAGATCGCCTTCCGAGCCGTGGGCGTGGC
TGCCGCCAATCACTTGAAAACATTGCTTTCCGAGAACGATTCCCTGACGGTCGGGACCGGTTGGGGCCGAACGATCGAAC
AGATGACCTTGCATCTGGCCGGCGTTCGGGCGCCGCATGCGCGCTTCATCTCGATCATGGGGTCGTTGACGGCAAACAAT
GCCTATAACCCGTTCGAAGTCGTGCACAGCCTCGCGAGACGCACCGGCGGCGAAGGTTATTTTCTTCCGGTGCCCTTCAT
CGCCGACTCGGTAGATGACAAAAAGGTCCTCATCTCACAACGTTCCGTGGTCAAGGCATTGGAAATCGCCCGCAGTGCTT
CCGTCTGCTTCATCAGCGCGGGTGAATTGACGGAGGAATCGCTTTTACGGCGCCAGGGCATGATCAGCGGCACCGAACTC
GAAAGCCTGCGGCAGGCCGGCGCCGTCGGCGACACCAACGGCATTTTCTTCGACAGCGAAGGGAGGCAGGTCGACCATGA
GCTCAACGAACGGACCATCGCACTGGGTTTCGAAGAGCTGAAGGCTCTGCCGGTGCTCCTGCTGATCGCCGGCCTGGAGA
AAATCCAGGCGGCCCGGGCCCTGCTTCGCAGCGGCGTCGTCAACGGTCTGATCATAGACGGCGATGCGGCCGAGGCGTTG
GCAGCGTTGGGCGAATAG

Upstream 100 bases:

>100_bases
GACCCACTTCCCCATTCGCGCTCACTAGGCGAATGCAGTCATGTAAATTGACAGCGTTACATTTGTCAACTTAAAATACA
TTTGTAAGGAAAGGGATGGA

Downstream 100 bases:

>100_bases
CTCGATCAGGATCCCTGCTACCAGCATGGCAATGCCAGTGTTGGAAACGGCCGCGATCGTGCGTCAGGCGCTTGTGCGCG
TCGAGATCGGGAAGCGCCTC

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MSEDDDALMVRAAWFYYVGGLNQEMTAARLGLTRARVNKMLAEARESGLVSISIDHRRVGVLPLEDRLRTRFGLDFCIST
PAFGFHDTSKQDSEVRKQIAFRAVGVAAANHLKTLLSENDSLTVGTGWGRTIEQMTLHLAGVRAPHARFISIMGSLTANN
AYNPFEVVHSLARRTGGEGYFLPVPFIADSVDDKKVLISQRSVVKALEIARSASVCFISAGELTEESLLRRQGMISGTEL
ESLRQAGAVGDTNGIFFDSEGRQVDHELNERTIALGFEELKALPVLLLIAGLEKIQAARALLRSGVVNGLIIDGDAAEAL
AALGE

Sequences:

>Translated_325_residues
MSEDDDALMVRAAWFYYVGGLNQEMTAARLGLTRARVNKMLAEARESGLVSISIDHRRVGVLPLEDRLRTRFGLDFCIST
PAFGFHDTSKQDSEVRKQIAFRAVGVAAANHLKTLLSENDSLTVGTGWGRTIEQMTLHLAGVRAPHARFISIMGSLTANN
AYNPFEVVHSLARRTGGEGYFLPVPFIADSVDDKKVLISQRSVVKALEIARSASVCFISAGELTEESLLRRQGMISGTEL
ESLRQAGAVGDTNGIFFDSEGRQVDHELNERTIALGFEELKALPVLLLIAGLEKIQAARALLRSGVVNGLIIDGDAAEAL
AALGE
>Mature_324_residues
SEDDDALMVRAAWFYYVGGLNQEMTAARLGLTRARVNKMLAEARESGLVSISIDHRRVGVLPLEDRLRTRFGLDFCISTP
AFGFHDTSKQDSEVRKQIAFRAVGVAAANHLKTLLSENDSLTVGTGWGRTIEQMTLHLAGVRAPHARFISIMGSLTANNA
YNPFEVVHSLARRTGGEGYFLPVPFIADSVDDKKVLISQRSVVKALEIARSASVCFISAGELTEESLLRRQGMISGTELE
SLRQAGAVGDTNGIFFDSEGRQVDHELNERTIALGFEELKALPVLLLIAGLEKIQAARALLRSGVVNGLIIDGDAAEALA
ALGE

Specific function: Regulates transcription of many different genes. In the absence of autoinducer 2 (AI-2), represses transcription of the lsr operon and its own transcription. In the presence of AI-2, lsrR is inactivated by binding phospho-AI-2, leading to the transcriptio

COG id: COG2390

COG function: function code K; Transcriptional regulator, contains sigma factor-related N-terminal domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sorC transcriptional regulatory family [H]

Homologues:

Organism=Escherichia coli, GI87082414, Length=319, Percent_Identity=28.2131661442006, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1787791, Length=333, Percent_Identity=28.2282282282282, Blast_Score=120, Evalue=8e-29,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04198 Sugar-bind [H]

EC number: NA

Molecular weight: Translated: 35238; Mature: 35107

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEDDDALMVRAAWFYYVGGLNQEMTAARLGLTRARVNKMLAEARESGLVSISIDHRRVG
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCEEE
VLPLEDRLRTRFGLDFCISTPAFGFHDTSKQDSEVRKQIAFRAVGVAAANHLKTLLSEND
ECCHHHHHHHHHCCHHEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SLTVGTGWGRTIEQMTLHLAGVRAPHARFISIMGSLTANNAYNPFEVVHSLARRTGGEGY
CEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCE
FLPVPFIADSVDDKKVLISQRSVVKALEIARSASVCFISAGELTEESLLRRQGMISGTEL
EEECCHHCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCCHHH
ESLRQAGAVGDTNGIFFDSEGRQVDHELNERTIALGFEELKALPVLLLIAGLEKIQAARA
HHHHHHCCCCCCCCEEECCCCCCHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHH
LLRSGVVNGLIIDGDAAEALAALGE
HHHCCCCCCEEECCCHHHHHHHHCC
>Mature Secondary Structure 
SEDDDALMVRAAWFYYVGGLNQEMTAARLGLTRARVNKMLAEARESGLVSISIDHRRVG
CCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCEEE
VLPLEDRLRTRFGLDFCISTPAFGFHDTSKQDSEVRKQIAFRAVGVAAANHLKTLLSEND
ECCHHHHHHHHHCCHHEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SLTVGTGWGRTIEQMTLHLAGVRAPHARFISIMGSLTANNAYNPFEVVHSLARRTGGEGY
CEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCE
FLPVPFIADSVDDKKVLISQRSVVKALEIARSASVCFISAGELTEESLLRRQGMISGTEL
EEECCHHCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCCHHH
ESLRQAGAVGDTNGIFFDSEGRQVDHELNERTIALGFEELKALPVLLLIAGLEKIQAARA
HHHHHHCCCCCCCCEEECCCCCCHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHH
LLRSGVVNGLIIDGDAAEALAALGE
HHHCCCCCCEEECCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA