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The map label for this gene is mcpA [H]

Identifier: 150398091

GI number: 150398091

Start: 3034164

End: 3035933

Strand: Direct

Name: mcpA [H]

Synonym: Smed_2893

Alternate gene names: 150398091

Gene position: 3034164-3035933 (Clockwise)

Preceding gene: 150398090

Following gene: 150398100

Centisome position: 80.23

GC content: 62.54

Gene sequence:

>1770_bases
ATGTTCTCTTTCACCAGGAGCCTGGACGCACGGCAGATCATCGAAGCCCTGTCCAAGTCGCAGGCCATCATTCAGTTCGA
TCTGACCGGCAAAGTCATCCACGCGAACGAAAACTTCTGCAGGACGCTCGGCTACAGCCTGCAAGAGATCACGGGCCAAC
ACCATAGCATCTTCTGCGCCCCCGATTTCGTGGCGTCCGAGGAGTATCGCCACTTCTGGGCTCGCCTCGGCCGCGGCGAG
TTCGACAGCAATGCCTATCGACGTCTCGCCAAGGGCGGACGGGAGGTCTGGATCCAGGCGAGCTACAATCCAGTCTTCCG
CAACGGCAAGCCCTACAAGGTCGTCAAATTCGCAGCCGACATCACCGCAGCCAAGATGAAGGCCACGGAAAATGCCGGCA
AACTCGATGCCATTTCCCGCTCGCAGGCGATGATCGAGTTCACCCCGACCGGCGAGGTCCTGAGCGCCAACGAGAACTTC
TGCGATACGCTTGGCTACCACCTCTCCGAAATTCAGGGCCGGCACCACAGCATGTTCTGCGAACCCACATATACCGCCAC
AACCGAATATGCAGACTTCTGGAAGCGGCTCGCCCAGGGAGAATTCATCGCCAACGAGTTCGTCCGCTATGGCAAGGGCG
GCAAGGAAGTCTGGATCCAGGCAGCCTACAACCCGATCCGCGATCCGAACGGCCGGGTCTGCAAGGTGGTGAAGTTCGCG
ACCGACGTCACCGAGCGCATGGCTGCAATCAATTCCCTCGGCGCCGGCCTGCGTGCGCTTGCCGAGGGCGATCTGGCACA
ATCGCTCGATACACCCTTCGTTCCGAGCATGGAAAGGGTGCGCAAGGACTTCAACGAAGCGCTTGTGCGCCTCTGTCGGG
CCATGCAGACGGTCGGCGAGAACGCCAGCGCGATCGCCGCTGGATCGCGCGAGATCCGATCGGCTGCCGACGATCTGTCG
AAGCGCACAGAACAGCAGGCGGCCTCCGTTGAAGAGACGGCCGCAGCACTGGACGAGATCACCACGACCGTGACAGGCTC
GAGCCGCCGCGCTGAGGAGGCAGGCAATCTGGTTGCGAAGACGAAGGACGGCGCCGAGCGTTCCGGCCTCGTCGTCAAAA
ACGCTATCAGCGCCATGGATCAGATCGAACAGTCCTCGCGCGAGATCAGCAACATCATCGGCGTCATCGACGACATCGCC
TTCCAGACGAACCTGCTGGCCCTGAATGCCGGCGTCGAGGCGGCACGTGCCGGAGAGGCCGGCAAGGGCTTTGCCGTGGT
GGCTCAGGAGGTCCGCGAGCTGGCGCAGCGCTCGGCAAGCGCCGCAAAGGACATCAAGGCCCTGATCACCGCTTCAGGCG
AGCATGTGAGGAACGGCGTATCGCTGGTCGGTCAGACCGGGACCGCCCTGGAGACCATCCTGGCGCAGATGCAGGAGATA
AATCACAACGTGTCGGCGATCGTGAAAGCCGCCCGAGAGCAGTCGACCGGCCTCAAGGAGATCAATCAGGCGGTCAATGC
AATGGACCAGACGACGCAGCAGAACGCCGCCATGGTGGAGGAAAGCACGGCCGCGAGCCACAGGATGTCTCAAGAGGCCG
ACGCGCTGCACGCCATGCTCCGTCAGTTCCGCATCGGAGGGGAAGCGCCGTCCGCAAGCGACAACAGGGCACCCCATCCG
GCCACGCAACTGCACCCGACCGCGAAGGCGCTGCGCGGCGGCACGAGATCCAACCTCGCACTCGTGCCCGCCGATTGGGA
GAATTTCTGA

Upstream 100 bases:

>100_bases
TGAGCCTGCGCATCGTCAGCTTTCTGAGAACGGTTCGGCAAAACGAATCGTCCGCCGACAATGCGGACCTGCGCGCGCAT
CAAAAATTTCAGAGGGGATC

Downstream 100 bases:

>100_bases
TCTCGGCAGCGCCGCGTCTGCTGTACTGAATCGTCCCTCCAGTCCAATGACTTGGGCTGGCTGGCAACTGTGTTTGTCAG
GTGGTTCGTCGGAAGGTTGT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 589; Mature: 589

Protein sequence:

>589_residues
MFSFTRSLDARQIIEALSKSQAIIQFDLTGKVIHANENFCRTLGYSLQEITGQHHSIFCAPDFVASEEYRHFWARLGRGE
FDSNAYRRLAKGGREVWIQASYNPVFRNGKPYKVVKFAADITAAKMKATENAGKLDAISRSQAMIEFTPTGEVLSANENF
CDTLGYHLSEIQGRHHSMFCEPTYTATTEYADFWKRLAQGEFIANEFVRYGKGGKEVWIQAAYNPIRDPNGRVCKVVKFA
TDVTERMAAINSLGAGLRALAEGDLAQSLDTPFVPSMERVRKDFNEALVRLCRAMQTVGENASAIAAGSREIRSAADDLS
KRTEQQAASVEETAAALDEITTTVTGSSRRAEEAGNLVAKTKDGAERSGLVVKNAISAMDQIEQSSREISNIIGVIDDIA
FQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELAQRSASAAKDIKALITASGEHVRNGVSLVGQTGTALETILAQMQEI
NHNVSAIVKAAREQSTGLKEINQAVNAMDQTTQQNAAMVEESTAASHRMSQEADALHAMLRQFRIGGEAPSASDNRAPHP
ATQLHPTAKALRGGTRSNLALVPADWENF

Sequences:

>Translated_589_residues
MFSFTRSLDARQIIEALSKSQAIIQFDLTGKVIHANENFCRTLGYSLQEITGQHHSIFCAPDFVASEEYRHFWARLGRGE
FDSNAYRRLAKGGREVWIQASYNPVFRNGKPYKVVKFAADITAAKMKATENAGKLDAISRSQAMIEFTPTGEVLSANENF
CDTLGYHLSEIQGRHHSMFCEPTYTATTEYADFWKRLAQGEFIANEFVRYGKGGKEVWIQAAYNPIRDPNGRVCKVVKFA
TDVTERMAAINSLGAGLRALAEGDLAQSLDTPFVPSMERVRKDFNEALVRLCRAMQTVGENASAIAAGSREIRSAADDLS
KRTEQQAASVEETAAALDEITTTVTGSSRRAEEAGNLVAKTKDGAERSGLVVKNAISAMDQIEQSSREISNIIGVIDDIA
FQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELAQRSASAAKDIKALITASGEHVRNGVSLVGQTGTALETILAQMQEI
NHNVSAIVKAAREQSTGLKEINQAVNAMDQTTQQNAAMVEESTAASHRMSQEADALHAMLRQFRIGGEAPSASDNRAPHP
ATQLHPTAKALRGGTRSNLALVPADWENF
>Mature_589_residues
MFSFTRSLDARQIIEALSKSQAIIQFDLTGKVIHANENFCRTLGYSLQEITGQHHSIFCAPDFVASEEYRHFWARLGRGE
FDSNAYRRLAKGGREVWIQASYNPVFRNGKPYKVVKFAADITAAKMKATENAGKLDAISRSQAMIEFTPTGEVLSANENF
CDTLGYHLSEIQGRHHSMFCEPTYTATTEYADFWKRLAQGEFIANEFVRYGKGGKEVWIQAAYNPIRDPNGRVCKVVKFA
TDVTERMAAINSLGAGLRALAEGDLAQSLDTPFVPSMERVRKDFNEALVRLCRAMQTVGENASAIAAGSREIRSAADDLS
KRTEQQAASVEETAAALDEITTTVTGSSRRAEEAGNLVAKTKDGAERSGLVVKNAISAMDQIEQSSREISNIIGVIDDIA
FQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELAQRSASAAKDIKALITASGEHVRNGVSLVGQTGTALETILAQMQEI
NHNVSAIVKAAREQSTGLKEINQAVNAMDQTTQQNAAMVEESTAASHRMSQEADALHAMLRQFRIGGEAPSASDNRAPHP
ATQLHPTAKALRGGTRSNLALVPADWENF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=530, Percent_Identity=30.188679245283, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI1788195, Length=335, Percent_Identity=40.2985074626866, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI2367378, Length=269, Percent_Identity=43.8661710037175, Blast_Score=195, Evalue=6e-51,
Organism=Escherichia coli, GI1787690, Length=303, Percent_Identity=39.2739273927393, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI1788194, Length=238, Percent_Identity=45.3781512605042, Blast_Score=186, Evalue=3e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 63991; Mature: 63991

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50113 PAC ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSFTRSLDARQIIEALSKSQAIIQFDLTGKVIHANENFCRTLGYSLQEITGQHHSIFCA
CCCCCCCCCHHHHHHHHCCCCEEEEEECCCEEEECCCHHHHHHCCHHHHHCCCCCEEEEC
PDFVASEEYRHFWARLGRGEFDSNAYRRLAKGGREVWIQASYNPVFRNGKPYKVVKFAAD
CCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEEEEHHH
ITAAKMKATENAGKLDAISRSQAMIEFTPTGEVLSANENFCDTLGYHLSEIQGRHHSMFC
HHHHHHHHCCCCCCCHHHCCCCEEEEECCCCCEEECCCCHHHHHHHHHHHHCCCCCCEEE
EPTYTATTEYADFWKRLAQGEFIANEFVRYGKGGKEVWIQAAYNPIRDPNGRVCKVVKFA
CCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHEEEEECCCCCCCCCCCEEHHHHHH
TDVTERMAAINSLGAGLRALAEGDLAQSLDTPFVPSMERVRKDFNEALVRLCRAMQTVGE
HHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
NASAIAAGSREIRSAADDLSKRTEQQAASVEETAAALDEITTTVTGSSRRAEEAGNLVAK
CCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCEEEE
TKDGAERSGLVVKNAISAMDQIEQSSREISNIIGVIDDIAFQTNLLALNAGVEAARAGEA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHCCCC
GKGFAVVAQEVRELAQRSASAAKDIKALITASGEHVRNGVSLVGQTGTALETILAQMQEI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHCCCCHHHHHHHHHHHHH
NHNVSAIVKAAREQSTGLKEINQAVNAMDQTTQQNAAMVEESTAASHRMSQEADALHAML
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQFRIGGEAPSASDNRAPHPATQLHPTAKALRGGTRSNLALVPADWENF
HHHHCCCCCCCCCCCCCCCCCHHCCHHHHHHCCCCCCCEEEECCCCCCC
>Mature Secondary Structure
MFSFTRSLDARQIIEALSKSQAIIQFDLTGKVIHANENFCRTLGYSLQEITGQHHSIFCA
CCCCCCCCCHHHHHHHHCCCCEEEEEECCCEEEECCCHHHHHHCCHHHHHCCCCCEEEEC
PDFVASEEYRHFWARLGRGEFDSNAYRRLAKGGREVWIQASYNPVFRNGKPYKVVKFAAD
CCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEEEEHHH
ITAAKMKATENAGKLDAISRSQAMIEFTPTGEVLSANENFCDTLGYHLSEIQGRHHSMFC
HHHHHHHHCCCCCCCHHHCCCCEEEEECCCCCEEECCCCHHHHHHHHHHHHCCCCCCEEE
EPTYTATTEYADFWKRLAQGEFIANEFVRYGKGGKEVWIQAAYNPIRDPNGRVCKVVKFA
CCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHEEEEECCCCCCCCCCCEEHHHHHH
TDVTERMAAINSLGAGLRALAEGDLAQSLDTPFVPSMERVRKDFNEALVRLCRAMQTVGE
HHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
NASAIAAGSREIRSAADDLSKRTEQQAASVEETAAALDEITTTVTGSSRRAEEAGNLVAK
CCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCEEEE
TKDGAERSGLVVKNAISAMDQIEQSSREISNIIGVIDDIAFQTNLLALNAGVEAARAGEA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHCCCC
GKGFAVVAQEVRELAQRSASAAKDIKALITASGEHVRNGVSLVGQTGTALETILAQMQEI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHCCCCHHHHHHHHHHHHH
NHNVSAIVKAAREQSTGLKEINQAVNAMDQTTQQNAAMVEESTAASHRMSQEADALHAML
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQFRIGGEAPSASDNRAPHPATQLHPTAKALRGGTRSNLALVPADWENF
HHHHCCCCCCCCCCCCCCCCCHHCCHHHHHHCCCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]