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The map label for this gene is yfmD [H]

Identifier: 150397691

GI number: 150397691

Start: 2576278

End: 2577300

Strand: Direct

Name: yfmD [H]

Synonym: Smed_2492

Alternate gene names: 150397691

Gene position: 2576278-2577300 (Clockwise)

Preceding gene: 150397690

Following gene: 150397692

Centisome position: 68.12

GC content: 58.94

Gene sequence:

>1023_bases
ATGGTGGTCATAGAGTCGGCGCGGCGCAACACCCCCGCGACGCGGATCTTTGCTTTTGGCCTGTTTGCGCTGCTGCTCGC
TCTGCTGAGCCTGTGGTCACTTACGATCGGCACCACTGCGATACCACTGGGTGATGCCTTGCGCGCGATAATATCGGAGG
GAACCAGCCATCAGGACGTAGTTATTTCCACTATCAGGTTACCACGAGTTCTCACCGCCATCATCGTAGGTTCGACATTG
GGCGTTGCCGGAGCCTTGATGCAGGCGGTCACAAACAATCCGCTGGCTTCGCCTGATCTGCTTGGCATAAGCGCCGGGGC
GGCTTTTGCGGTCGTTATATCCATCGTCTTCTTCGACGCGCAATCTCCGCTGGTGTTCCTGTGGTTCGCCTTTGGCGGCG
CCGCAGTAGCAGGGATCCTCGTTTATATGGTCGCGTCAACCGGCGTGTCCGGTGTGACCCCGGTGAAGCTCGCCCTGTCA
GGCGCGGTGTTGAGCGTTTTCCTCGGCTCGGTGTCCGCATCGCTGCTCATCTTCGACATGAAAGCCATCGACATTATCAG
GTTGTGGTCCGTTGGTTCATTGACGGGAAAGGATATGGCTGCCGTGGCAGCCGTGGCGCCTTTTGCCCTGGCAGGAGTTG
CTGCCACTCTGCTGCTGGCAAGAGAGGTGAGCACACTCAGTCTCGGGGCGGATGTCGCGCAGGCCGTCGGTCAGAATGTC
CTTTTATGGAGACTCGTTTCGGGAGCCCTCATGGTCCTGATGGCGGGAAGTTCGGTTGCGCTGGCAGGTCCTATCGGGTT
TGTCGGACTTGTGGTGCCACACATCGTGCGCTTGAGCCTCGGCACTGACTACCGCTGGATTCTTCCCTTCTGTGCAATTT
CGGGAGCGTTATTGGTTGTCATGGCAGACGGTCTGCAAAGAAGTTTGACGGGAATCGACGTTCCGGTTGGCGTGACGCTT
GCCCTGGTGGGGGCTCCATTCTTCATCTGGCTGGCGCGGTTGCGCGCCGGTGGGATTGGTTGA

Upstream 100 bases:

>100_bases
TATCGAGTAGACGCAGGCACCTGGATAGAGTTCAACGGTCTGGCGTCGGCCAATAAGATTCTCGATGACATCGAGACTTA
CATCATCCCGAGGCCGTGAA

Downstream 100 bases:

>100_bases
TGCGAAGCGTTCTCATCCTATCGGGCTTTTCGGTCGTCATACTGTTCTTGGCGCTTGCGATTGGTGACCACCATGTCAGC
ATCGCACAAATCCTTGCAGT

Product: transport system permease

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: Ferric-citrate import system permease protein [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MVVIESARRNTPATRIFAFGLFALLLALLSLWSLTIGTTAIPLGDALRAIISEGTSHQDVVISTIRLPRVLTAIIVGSTL
GVAGALMQAVTNNPLASPDLLGISAGAAFAVVISIVFFDAQSPLVFLWFAFGGAAVAGILVYMVASTGVSGVTPVKLALS
GAVLSVFLGSVSASLLIFDMKAIDIIRLWSVGSLTGKDMAAVAAVAPFALAGVAATLLLAREVSTLSLGADVAQAVGQNV
LLWRLVSGALMVLMAGSSVALAGPIGFVGLVVPHIVRLSLGTDYRWILPFCAISGALLVVMADGLQRSLTGIDVPVGVTL
ALVGAPFFIWLARLRAGGIG

Sequences:

>Translated_340_residues
MVVIESARRNTPATRIFAFGLFALLLALLSLWSLTIGTTAIPLGDALRAIISEGTSHQDVVISTIRLPRVLTAIIVGSTL
GVAGALMQAVTNNPLASPDLLGISAGAAFAVVISIVFFDAQSPLVFLWFAFGGAAVAGILVYMVASTGVSGVTPVKLALS
GAVLSVFLGSVSASLLIFDMKAIDIIRLWSVGSLTGKDMAAVAAVAPFALAGVAATLLLAREVSTLSLGADVAQAVGQNV
LLWRLVSGALMVLMAGSSVALAGPIGFVGLVVPHIVRLSLGTDYRWILPFCAISGALLVVMADGLQRSLTGIDVPVGVTL
ALVGAPFFIWLARLRAGGIG
>Mature_340_residues
MVVIESARRNTPATRIFAFGLFALLLALLSLWSLTIGTTAIPLGDALRAIISEGTSHQDVVISTIRLPRVLTAIIVGSTL
GVAGALMQAVTNNPLASPDLLGISAGAAFAVVISIVFFDAQSPLVFLWFAFGGAAVAGILVYMVASTGVSGVTPVKLALS
GAVLSVFLGSVSASLLIFDMKAIDIIRLWSVGSLTGKDMAAVAAVAPFALAGVAATLLLAREVSTLSLGADVAQAVGQNV
LLWRLVSGALMVLMAGSSVALAGPIGFVGLVVPHIVRLSLGTDYRWILPFCAISGALLVVMADGLQRSLTGIDVPVGVTL
ALVGAPFFIWLARLRAGGIG

Specific function: Part of the ABC transporter complex yfmCDEF involved in citrate-dependent Fe(3+) import. Involved in the translocation of the substrate across the membrane (Probable) [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786805, Length=307, Percent_Identity=36.8078175895765, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1790740, Length=317, Percent_Identity=37.5394321766561, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1790741, Length=305, Percent_Identity=36.3934426229508, Blast_Score=137, Evalue=9e-34,
Organism=Escherichia coli, GI1788004, Length=291, Percent_Identity=35.3951890034364, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1786347, Length=282, Percent_Identity=32.9787234042553, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1786804, Length=257, Percent_Identity=32.6848249027237, Blast_Score=105, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 34713; Mature: 34713

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVIESARRNTPATRIFAFGLFALLLALLSLWSLTIGTTAIPLGDALRAIISEGTSHQDV
CEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHH
VISTIRLPRVLTAIIVGSTLGVAGALMQAVTNNPLASPDLLGISAGAAFAVVISIVFFDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHCC
QSPLVFLWFAFGGAAVAGILVYMVASTGVSGVTPVKLALSGAVLSVFLGSVSASLLIFDM
CCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEH
KAIDIIRLWSVGSLTGKDMAAVAAVAPFALAGVAATLLLAREVSTLSLGADVAQAVGQNV
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LLWRLVSGALMVLMAGSSVALAGPIGFVGLVVPHIVRLSLGTDYRWILPFCAISGALLVV
HHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
MADGLQRSLTGIDVPVGVTLALVGAPFFIWLARLRAGGIG
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVVIESARRNTPATRIFAFGLFALLLALLSLWSLTIGTTAIPLGDALRAIISEGTSHQDV
CEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHH
VISTIRLPRVLTAIIVGSTLGVAGALMQAVTNNPLASPDLLGISAGAAFAVVISIVFFDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHCC
QSPLVFLWFAFGGAAVAGILVYMVASTGVSGVTPVKLALSGAVLSVFLGSVSASLLIFDM
CCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEH
KAIDIIRLWSVGSLTGKDMAAVAAVAPFALAGVAATLLLAREVSTLSLGADVAQAVGQNV
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LLWRLVSGALMVLMAGSSVALAGPIGFVGLVVPHIVRLSLGTDYRWILPFCAISGALLVV
HHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
MADGLQRSLTGIDVPVGVTLALVGAPFFIWLARLRAGGIG
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377 [H]