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The map label for this gene is yfhA [H]

Identifier: 150397692

GI number: 150397692

Start: 2577300

End: 2578277

Strand: Direct

Name: yfhA [H]

Synonym: Smed_2493

Alternate gene names: 150397692

Gene position: 2577300-2578277 (Clockwise)

Preceding gene: 150397691

Following gene: 150397693

Centisome position: 68.15

GC content: 59.82

Gene sequence:

>978_bases
ATGCGAAGCGTTCTCATCCTATCGGGCTTTTCGGTCGTCATACTGTTCTTGGCGCTTGCGATTGGTGACCACCATGTCAG
CATCGCACAAATCCTTGCAGTCCTCACCGACAGCCCGGCGGCGGATGCACAGTCCATACAGATTATCCGCGATATTCGTC
TTCCAAGGGTTATTTTGGGCTTCCTTGTTGGCGCATCGCTTGCCACTGCGGGTATGATTGCCCAGTCGGTGTTGCGAAAT
CCATTGGCGGAACCGGGTCTGATCGGTGTCAATGCCGGCGCTGCCCTTGCAGCGGTCATTGTCATCGTCAGGTTCGAGGT
GCCTCCCACACACCTGCTTTCGTGGCTGGCATTTGCCGGAGCCCTCACAATGTCCCTCGCGATCTATGCCTTGTCATGGA
ACAGCGGCAGTTCTTCGCTGCGCATCATTCTCATCGGCATCGGCCTCAGTTCGCTAGCCGGGGCCGGCGCAAACTTCATC
TCCACCTTCGGAAACCCCCAGGCCGTGCAGCGAGCGATGGTCTGGCTTTCCGGCAGCATCTACAACAGCACCTGGGATAA
AATCCGTACCCTCGCGACATGGCTCACGATAGGCATAGCGGGCAGTGCCCTGATCGCGCGGGAAATGGACCTGCTTATCC
TGGGGGACGAGACCGCAAGGGCGCGGGGGCAACCAGTAGAACTGATCCGAGCCGTCATGTTCGTCCTTTGCGCTGTCCTG
TCTGGCGCCGCAGTCGCTGCGGCAGGTCTGGTGGCATTCGTTGGTCTGATCGCACCGCACATTGCTCGCGCGCTCGTAGG
GCATTCCCACGGTCTCATGCTGCCGGTCACCGCGCTTGCCGGCGGACTTCTGGTGGTCGGAGCCGACCTTGCGGCGCGCA
CGTTGTTTACGCCAGCGCCGCTGCCCGTCGGATTGATGACGGCTATTCTGGGCGCGCCATTCTTTGCTTACCTCATGTGG
CGGAAGAAAAATGCCTGA

Upstream 100 bases:

>100_bases
GTTTGACGGGAATCGACGTTCCGGTTGGCGTGACGCTTGCCCTGGTGGGGGCTCCATTCTTCATCTGGCTGGCGCGGTTG
CGCGCCGGTGGGATTGGTTG

Downstream 100 bases:

>100_bases
ACAGCTTGCCCTTCCTATCCTTGAAACCCGCGCTGCCTCGATCGGATATGGCGCCAGGCTTATCCTGCGAGATCTCGACT
TATCCGTTCCAGAAGCTTCC

Product: transport system permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MRSVLILSGFSVVILFLALAIGDHHVSIAQILAVLTDSPAADAQSIQIIRDIRLPRVILGFLVGASLATAGMIAQSVLRN
PLAEPGLIGVNAGAALAAVIVIVRFEVPPTHLLSWLAFAGALTMSLAIYALSWNSGSSSLRIILIGIGLSSLAGAGANFI
STFGNPQAVQRAMVWLSGSIYNSTWDKIRTLATWLTIGIAGSALIAREMDLLILGDETARARGQPVELIRAVMFVLCAVL
SGAAVAAAGLVAFVGLIAPHIARALVGHSHGLMLPVTALAGGLLVVGADLAARTLFTPAPLPVGLMTAILGAPFFAYLMW
RKKNA

Sequences:

>Translated_325_residues
MRSVLILSGFSVVILFLALAIGDHHVSIAQILAVLTDSPAADAQSIQIIRDIRLPRVILGFLVGASLATAGMIAQSVLRN
PLAEPGLIGVNAGAALAAVIVIVRFEVPPTHLLSWLAFAGALTMSLAIYALSWNSGSSSLRIILIGIGLSSLAGAGANFI
STFGNPQAVQRAMVWLSGSIYNSTWDKIRTLATWLTIGIAGSALIAREMDLLILGDETARARGQPVELIRAVMFVLCAVL
SGAAVAAAGLVAFVGLIAPHIARALVGHSHGLMLPVTALAGGLLVVGADLAARTLFTPAPLPVGLMTAILGAPFFAYLMW
RKKNA
>Mature_325_residues
MRSVLILSGFSVVILFLALAIGDHHVSIAQILAVLTDSPAADAQSIQIIRDIRLPRVILGFLVGASLATAGMIAQSVLRN
PLAEPGLIGVNAGAALAAVIVIVRFEVPPTHLLSWLAFAGALTMSLAIYALSWNSGSSSLRIILIGIGLSSLAGAGANFI
STFGNPQAVQRAMVWLSGSIYNSTWDKIRTLATWLTIGIAGSALIAREMDLLILGDETARARGQPVELIRAVMFVLCAVL
SGAAVAAAGLVAFVGLIAPHIARALVGHSHGLMLPVTALAGGLLVVGADLAARTLFTPAPLPVGLMTAILGAPFFAYLMW
RKKNA

Specific function: Part of the ABC transporter complex yfiYZ/yfhA/yusV involved in import of the iron-hydroxamate siderophores schizokinen, arthrobactin and corprogen (Probable) [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=291, Percent_Identity=36.0824742268041, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1786804, Length=326, Percent_Identity=35.5828220858896, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1786347, Length=275, Percent_Identity=34.9090909090909, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1790741, Length=278, Percent_Identity=33.4532374100719, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1786805, Length=290, Percent_Identity=35.5172413793103, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1788004, Length=277, Percent_Identity=34.6570397111913, Blast_Score=115, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 33675; Mature: 33675

Theoretical pI: Translated: 10.71; Mature: 10.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSVLILSGFSVVILFLALAIGDHHVSIAQILAVLTDSPAADAQSIQIIRDIRLPRVILG
CCCEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCHHHHHHH
FLVGASLATAGMIAQSVLRNPLAEPGLIGVNAGAALAAVIVIVRFEVPPTHLLSWLAFAG
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
ALTMSLAIYALSWNSGSSSLRIILIGIGLSSLAGAGANFISTFGNPQAVQRAMVWLSGSI
HHHHHHHHHEEEECCCCCCEEEEEEECCHHHHHCCCCHHHHHCCCHHHHHHHHHHHCCCH
YNSTWDKIRTLATWLTIGIAGSALIAREMDLLILGDETARARGQPVELIRAVMFVLCAVL
HHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEEEECCCHHHCCCCHHHHHHHHHHHHHHHH
SGAAVAAAGLVAFVGLIAPHIARALVGHSHGLMLPVTALAGGLLVVGADLAARTLFTPAP
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHCCCEEEECHHHHHHHCCCCC
LPVGLMTAILGAPFFAYLMWRKKNA
CCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRSVLILSGFSVVILFLALAIGDHHVSIAQILAVLTDSPAADAQSIQIIRDIRLPRVILG
CCCEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCHHHHHHH
FLVGASLATAGMIAQSVLRNPLAEPGLIGVNAGAALAAVIVIVRFEVPPTHLLSWLAFAG
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
ALTMSLAIYALSWNSGSSSLRIILIGIGLSSLAGAGANFISTFGNPQAVQRAMVWLSGSI
HHHHHHHHHEEEECCCCCCEEEEEEECCHHHHHCCCCHHHHHCCCHHHHHHHHHHHCCCH
YNSTWDKIRTLATWLTIGIAGSALIAREMDLLILGDETARARGQPVELIRAVMFVLCAVL
HHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEEEECCCHHHCCCCHHHHHHHHHHHHHHHH
SGAAVAAAGLVAFVGLIAPHIARALVGHSHGLMLPVTALAGGLLVVGADLAARTLFTPAP
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHCCCEEEECHHHHHHHCCCCC
LPVGLMTAILGAPFFAYLMWRKKNA
CCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]