| Definition | Sinorhizobium medicae WSM419 chromosome, complete genome. |
|---|---|
| Accession | NC_009636 |
| Length | 3,781,904 |
Click here to switch to the map view.
The map label for this gene is kduD [H]
Identifier: 150397648
GI number: 150397648
Start: 2530702
End: 2531493
Strand: Reverse
Name: kduD [H]
Synonym: Smed_2448
Alternate gene names: 150397648
Gene position: 2531493-2530702 (Counterclockwise)
Preceding gene: 150397649
Following gene: 150397647
Centisome position: 66.94
GC content: 67.55
Gene sequence:
>792_bases ATGTCGACCAGTTCATCCGCTGACGGGCGGACCCGCGCGACCGGCAGTCCCGCCGCCTTCCTGCGCCCCGGCCTTTTCGA AGGGCGGCAGGTGCTGGTGAGCGGCGGGACCTCAGGTATCGGCGCTGCGATCTGCGAGGCCTTCGCCGCGCTCGGGGCCG ATGTCCTCGCAACGGGCATCACCGAGGCGGAGATTGCCGCCGCCGGAAGCCGGCCCGGACTTCAGGACGTGCAGTTCGCC ACGCTCGACGTGCGCGACAGGTCTGCCGTGGATGCTCTGGTCGCCGGCCTGCCGCGGCTGGACCACGTGGTGAACTGCGC CGGCGTGATCCGCCGCAATGACGAACTCGAGCCGGATGTGTTCGCCGACGTCGTCGATATCAATCTCAACGGCTCCATGC GCGTCTGCGCGGCAGCCCGTCCACGGCTTGCGGAAACCGGCGGCACGATCGTCAATACCGCCTCCATGCTGTCGTTCTTC GGCGGTGGCCTGGTGCCCGGCTATTCCGCATCGAAGGGCGGCATCGCCCAGCTCACCAAATCGCTGGCGATCGCCTATGC GGCCGATGCAATCCGGGTGAATGCCATCGCGCCGGGTTGGATCGCGACACCCCTGACGAAGGCGCTACGGGAGAGCCCGG AGCGCAACGCGGCCATTCTCGGCCGCACGCCGCTCAATCGCTGGGGAGAGCCGGCGGAAGTCGCCGGTGGCGTTCTTTAT CTGTCCTCGCCGCTTGCAAGCTTCGTTACCGGCAGCGTGCTGGTCATCGATGGCGGCTATCTGATCATGTGA
Upstream 100 bases:
>100_bases TATGTCGACGCCTTCGGCGAGCCGCTCGGCTTCGAGGACGTCTTCACCAAGATCGATATGTGTCGCGCGCATTACGAAGC GGTCGGACTGGGGGCGGATT
Downstream 100 bases:
>100_bases GGCACGATATGAAAGCCATTGTTCTCCCCGGACCGCAGGCGCAAATTGACAACGTGACACTGACCGACCTGCCGACCCCG GAGCCCGGGCCGGGCGAACT
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: 2-keto-3-deoxygluconate 5-dehydrogenase; 2-keto-3-deoxygluconate oxidoreductase; KDG oxidoreductase [H]
Number of amino acids: Translated: 263; Mature: 262
Protein sequence:
>263_residues MSTSSSADGRTRATGSPAAFLRPGLFEGRQVLVSGGTSGIGAAICEAFAALGADVLATGITEAEIAAAGSRPGLQDVQFA TLDVRDRSAVDALVAGLPRLDHVVNCAGVIRRNDELEPDVFADVVDINLNGSMRVCAAARPRLAETGGTIVNTASMLSFF GGGLVPGYSASKGGIAQLTKSLAIAYAADAIRVNAIAPGWIATPLTKALRESPERNAAILGRTPLNRWGEPAEVAGGVLY LSSPLASFVTGSVLVIDGGYLIM
Sequences:
>Translated_263_residues MSTSSSADGRTRATGSPAAFLRPGLFEGRQVLVSGGTSGIGAAICEAFAALGADVLATGITEAEIAAAGSRPGLQDVQFA TLDVRDRSAVDALVAGLPRLDHVVNCAGVIRRNDELEPDVFADVVDINLNGSMRVCAAARPRLAETGGTIVNTASMLSFF GGGLVPGYSASKGGIAQLTKSLAIAYAADAIRVNAIAPGWIATPLTKALRESPERNAAILGRTPLNRWGEPAEVAGGVLY LSSPLASFVTGSVLVIDGGYLIM >Mature_262_residues STSSSADGRTRATGSPAAFLRPGLFEGRQVLVSGGTSGIGAAICEAFAALGADVLATGITEAEIAAAGSRPGLQDVQFAT LDVRDRSAVDALVAGLPRLDHVVNCAGVIRRNDELEPDVFADVVDINLNGSMRVCAAARPRLAETGGTIVNTASMLSFFG GGLVPGYSASKGGIAQLTKSLAIAYAADAIRVNAIAPGWIATPLTKALRESPERNAAILGRTPLNRWGEPAEVAGGVLYL SSPLASFVTGSVLVIDGGYLIM
Specific function: Catalyzes the reduction of 2,5-diketo-3-deoxygluconate (DKII or 4,6-dihydroxy-2,5-dioxohexanoate) into 2-keto-3- deoxygluconate (KDG or 2-dehydro-3-deoxygluconate) with a concomitant oxidation of NADH [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI40254992, Length=242, Percent_Identity=37.603305785124, Blast_Score=110, Evalue=2e-24, Organism=Homo sapiens, GI10190704, Length=254, Percent_Identity=33.4645669291339, Blast_Score=100, Evalue=2e-21, Organism=Homo sapiens, GI66933014, Length=246, Percent_Identity=31.7073170731707, Blast_Score=96, Evalue=3e-20, Organism=Homo sapiens, GI7705925, Length=241, Percent_Identity=29.8755186721992, Blast_Score=94, Evalue=9e-20, Organism=Homo sapiens, GI19923817, Length=264, Percent_Identity=29.1666666666667, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI59889578, Length=192, Percent_Identity=34.375, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI15277342, Length=252, Percent_Identity=30.5555555555556, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI4758504, Length=254, Percent_Identity=32.2834645669291, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI32483357, Length=240, Percent_Identity=31.25, Blast_Score=79, Evalue=6e-15, Organism=Homo sapiens, GI4503301, Length=258, Percent_Identity=27.5193798449612, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI5031737, Length=246, Percent_Identity=26.0162601626016, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI83715985, Length=255, Percent_Identity=30.1960784313725, Blast_Score=67, Evalue=2e-11, Organism=Escherichia coli, GI1789208, Length=251, Percent_Identity=37.4501992031873, Blast_Score=146, Evalue=1e-36, Organism=Escherichia coli, GI87082160, Length=247, Percent_Identity=32.3886639676113, Blast_Score=135, Evalue=3e-33, Organism=Escherichia coli, GI1790717, Length=245, Percent_Identity=33.8775510204082, Blast_Score=134, Evalue=5e-33, Organism=Escherichia coli, GI1787335, Length=245, Percent_Identity=33.8775510204082, Blast_Score=119, Evalue=2e-28, Organism=Escherichia coli, GI87082100, Length=260, Percent_Identity=33.4615384615385, Blast_Score=103, Evalue=8e-24, Organism=Escherichia coli, GI2367175, Length=248, Percent_Identity=31.8548387096774, Blast_Score=86, Evalue=2e-18, Organism=Escherichia coli, GI1786812, Length=251, Percent_Identity=29.8804780876494, Blast_Score=85, Evalue=5e-18, Organism=Escherichia coli, GI1789378, Length=257, Percent_Identity=31.1284046692607, Blast_Score=82, Evalue=4e-17, Organism=Escherichia coli, GI1788459, Length=246, Percent_Identity=28.8617886178862, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI2367365, Length=250, Percent_Identity=32.4, Blast_Score=80, Evalue=2e-16, Organism=Escherichia coli, GI1787905, Length=250, Percent_Identity=28.4, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI1787820, Length=180, Percent_Identity=30, Blast_Score=67, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17555706, Length=258, Percent_Identity=34.1085271317829, Blast_Score=117, Evalue=5e-27, Organism=Caenorhabditis elegans, GI25147288, Length=246, Percent_Identity=33.3333333333333, Blast_Score=111, Evalue=4e-25, Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=32.2709163346614, Blast_Score=107, Evalue=6e-24, Organism=Caenorhabditis elegans, GI71994604, Length=249, Percent_Identity=32.5301204819277, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17561402, Length=249, Percent_Identity=29.3172690763052, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17538182, Length=250, Percent_Identity=30, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17544670, Length=260, Percent_Identity=27.3076923076923, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17536025, Length=266, Percent_Identity=28.9473684210526, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17536651, Length=255, Percent_Identity=29.4117647058824, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17560676, Length=241, Percent_Identity=29.4605809128631, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI17538480, Length=263, Percent_Identity=27.3764258555133, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI115534694, Length=244, Percent_Identity=27.4590163934426, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17559104, Length=265, Percent_Identity=28.6792452830189, Blast_Score=80, Evalue=7e-16, Organism=Caenorhabditis elegans, GI17560150, Length=258, Percent_Identity=25.1937984496124, Blast_Score=80, Evalue=8e-16, Organism=Caenorhabditis elegans, GI17562990, Length=260, Percent_Identity=26.5384615384615, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17561272, Length=263, Percent_Identity=30.4182509505703, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17562910, Length=266, Percent_Identity=27.0676691729323, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI72000259, Length=258, Percent_Identity=26.3565891472868, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17563726, Length=256, Percent_Identity=27.34375, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17551412, Length=262, Percent_Identity=25.5725190839695, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17562904, Length=260, Percent_Identity=24.6153846153846, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17562906, Length=264, Percent_Identity=28.030303030303, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17560220, Length=258, Percent_Identity=25.968992248062, Blast_Score=74, Evalue=7e-14, Organism=Caenorhabditis elegans, GI193204405, Length=262, Percent_Identity=27.4809160305344, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17531453, Length=260, Percent_Identity=28.0769230769231, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17562908, Length=266, Percent_Identity=28.1954887218045, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17565030, Length=269, Percent_Identity=25.6505576208178, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17560332, Length=265, Percent_Identity=26.7924528301887, Blast_Score=67, Evalue=9e-12, Organism=Caenorhabditis elegans, GI17538486, Length=263, Percent_Identity=23.9543726235741, Blast_Score=64, Evalue=8e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=273, Percent_Identity=32.2344322344322, Blast_Score=111, Evalue=1e-25, Organism=Saccharomyces cerevisiae, GI6322861, Length=192, Percent_Identity=29.1666666666667, Blast_Score=73, Evalue=4e-14, Organism=Drosophila melanogaster, GI24643142, Length=235, Percent_Identity=33.6170212765957, Blast_Score=112, Evalue=3e-25, Organism=Drosophila melanogaster, GI23397609, Length=244, Percent_Identity=32.7868852459016, Blast_Score=107, Evalue=1e-23, Organism=Drosophila melanogaster, GI24639444, Length=247, Percent_Identity=31.5789473684211, Blast_Score=99, Evalue=2e-21, Organism=Drosophila melanogaster, GI21357041, Length=260, Percent_Identity=32.6923076923077, Blast_Score=94, Evalue=1e-19, Organism=Drosophila melanogaster, GI28571526, Length=253, Percent_Identity=31.6205533596838, Blast_Score=94, Evalue=1e-19, Organism=Drosophila melanogaster, GI21355319, Length=251, Percent_Identity=29.8804780876494, Blast_Score=88, Evalue=5e-18, Organism=Drosophila melanogaster, GI24644339, Length=261, Percent_Identity=31.0344827586207, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI24644337, Length=171, Percent_Identity=35.0877192982456, Blast_Score=86, Evalue=3e-17, Organism=Drosophila melanogaster, GI17737361, Length=254, Percent_Identity=32.2834645669291, Blast_Score=84, Evalue=1e-16,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011286 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.127 [H]
Molecular weight: Translated: 26825; Mature: 26694
Theoretical pI: Translated: 5.04; Mature: 5.04
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.1 %Cys (Translated Protein) 1.5 %Met (Translated Protein) 2.7 %Cys+Met (Translated Protein) 1.1 %Cys (Mature Protein) 1.1 %Met (Mature Protein) 2.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSTSSSADGRTRATGSPAAFLRPGLFEGRQVLVSGGTSGIGAAICEAFAALGADVLATGI CCCCCCCCCCCCCCCCCHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCHHHHHHCC TEAEIAAAGSRPGLQDVQFATLDVRDRSAVDALVAGLPRLDHVVNCAGVIRRNDELEPDV CHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCC FADVVDINLNGSMRVCAAARPRLAETGGTIVNTASMLSFFGGGLVPGYSASKGGIAQLTK EEEEEEEECCCCEEEEECCCCCHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHH SLAIAYAADAIRVNAIAPGWIATPLTKALRESPERNAAILGRTPLNRWGEPAEVAGGVLY HHHHHHHHCCEEEEEECCCHHHHHHHHHHHCCCCCCCEEEECCCHHHCCCHHHHHCCEEE LSSPLASFVTGSVLVIDGGYLIM EHHHHHHHHCCCEEEEECCEEEC >Mature Secondary Structure STSSSADGRTRATGSPAAFLRPGLFEGRQVLVSGGTSGIGAAICEAFAALGADVLATGI CCCCCCCCCCCCCCCCHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCHHHHHHCC TEAEIAAAGSRPGLQDVQFATLDVRDRSAVDALVAGLPRLDHVVNCAGVIRRNDELEPDV CHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCC FADVVDINLNGSMRVCAAARPRLAETGGTIVNTASMLSFFGGGLVPGYSASKGGIAQLTK EEEEEEEECCCCEEEEECCCCCHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHH SLAIAYAADAIRVNAIAPGWIATPLTKALRESPERNAAILGRTPLNRWGEPAEVAGGVLY HHHHHHHHCCEEEEEECCCHHHHHHHHHHHCCCCCCCEEEECCCHHHCCCHHHHHCCEEE LSSPLASFVTGSVLVIDGGYLIM EHHHHHHHHCCCEEEEECCEEEC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 8760912; 9384377 [H]