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The map label for this gene is nudL [H]

Identifier: 150397473

GI number: 150397473

Start: 2348926

End: 2349558

Strand: Reverse

Name: nudL [H]

Synonym: Smed_2273

Alternate gene names: 150397473

Gene position: 2349558-2348926 (Counterclockwise)

Preceding gene: 150397474

Following gene: 150397472

Centisome position: 62.13

GC content: 60.66

Gene sequence:

>633_bases
ATGAGCAGTCGCCCATATTCCGCCGACGAGTTCCGTCGCCGTGCGCTGCAGCAGGCGGGAGGACCAATCGAAACCGCCTG
GCGCGATCACGGCGATTTCCTGCTGAACCCCGGGATCGTTCCCTATGTCGAGTCCCTGCATCTTAAGGATGCCGCGGTCC
TCGTTCCTGTTGTCGACGACGGGGACGATGCCAGCGTGATCTTCACGCAACGCACCTCCAATTTGCGCAAACATTCCGGC
CAGGTGGCTTTTCCGGGAGGCGCGGTGGATCCAGAGGACCTCTCTATCGAAGTGGCTGCGATCCGCGAGGCGGAGGAGGA
GATCGGCCTCGACCCGCGGTTCGTCGAAACGGTCGCGCGGCTGCCGCATTACATGGCGATGTCCGGTTTTCGTATCACGC
CGGTGCTTGCGGTGGTCCAGCCGGGTTTCGTGCTCGAACCGAATCCGCAGGAAGTGGAAAGCGTGTTCGACGTGCCGTTG
TCCTTCCTCATGAATCCGCAAAATCACGAACGCGGAAGCAGTCACTGGCAGGGCGCGGAGCGCCATTTCTACCGTATGCC
CTATGGCGAAAGAAACATCTGGGGGATCACCGCAGGGATCGTCCGCATGCTCTATGAAAGGCTCTATGCATGA

Upstream 100 bases:

>100_bases
GCCACACCGTCGCGGTCGGCGGCGTGGACATGTTCTGCATCAAATCGGCTGGAGCGGTCTTCCCGATCATGCCCGCGGCC
GAGCTGGAAGCGCTGTCTCG

Downstream 100 bases:

>100_bases
CTTCCATTGCCGCCGAGCCCTGGTTCCAGGCTCCTCAGCTTCGCCGCATATTCGACCTGTTGAATGCCGATGGCGGCGAG
GTTCGGATCGTCGGAGGGGC

Product: NUDIX hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 209

Protein sequence:

>210_residues
MSSRPYSADEFRRRALQQAGGPIETAWRDHGDFLLNPGIVPYVESLHLKDAAVLVPVVDDGDDASVIFTQRTSNLRKHSG
QVAFPGGAVDPEDLSIEVAAIREAEEEIGLDPRFVETVARLPHYMAMSGFRITPVLAVVQPGFVLEPNPQEVESVFDVPL
SFLMNPQNHERGSSHWQGAERHFYRMPYGERNIWGITAGIVRMLYERLYA

Sequences:

>Translated_210_residues
MSSRPYSADEFRRRALQQAGGPIETAWRDHGDFLLNPGIVPYVESLHLKDAAVLVPVVDDGDDASVIFTQRTSNLRKHSG
QVAFPGGAVDPEDLSIEVAAIREAEEEIGLDPRFVETVARLPHYMAMSGFRITPVLAVVQPGFVLEPNPQEVESVFDVPL
SFLMNPQNHERGSSHWQGAERHFYRMPYGERNIWGITAGIVRMLYERLYA
>Mature_209_residues
SSRPYSADEFRRRALQQAGGPIETAWRDHGDFLLNPGIVPYVESLHLKDAAVLVPVVDDGDDASVIFTQRTSNLRKHSGQ
VAFPGGAVDPEDLSIEVAAIREAEEEIGLDPRFVETVARLPHYMAMSGFRITPVLAVVQPGFVLEPNPQEVESVFDVPLS
FLMNPQNHERGSSHWQGAERHFYRMPYGERNIWGITAGIVRMLYERLYA

Specific function: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI157785656, Length=120, Percent_Identity=40, Blast_Score=97, Evalue=1e-20,
Organism=Escherichia coli, GI1788115, Length=161, Percent_Identity=38.5093167701863, Blast_Score=96, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17536993, Length=141, Percent_Identity=36.1702127659575, Blast_Score=74, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17510677, Length=128, Percent_Identity=39.84375, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI18859683, Length=168, Percent_Identity=33.9285714285714, Blast_Score=74, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR000059 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 23545; Mature: 23414

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSRPYSADEFRRRALQQAGGPIETAWRDHGDFLLNPGIVPYVESLHLKDAAVLVPVVDD
CCCCCCCHHHHHHHHHHHCCCCCCHHHCCCCCEEECCCCHHHHHHHCCCCCEEEEEEECC
GDDASVIFTQRTSNLRKHSGQVAFPGGAVDPEDLSIEVAAIREAEEEIGLDPRFVETVAR
CCCCEEEEECCHHHHHHHCCCEECCCCCCCCCCCEEEEHHHHHHHHHHCCCHHHHHHHHH
LPHYMAMSGFRITPVLAVVQPGFVLEPNPQEVESVFDVPLSFLMNPQNHERGSSHWQGAE
CHHHHHHCCCCHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHH
RHFYRMPYGERNIWGITAGIVRMLYERLYA
HHEEECCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SSRPYSADEFRRRALQQAGGPIETAWRDHGDFLLNPGIVPYVESLHLKDAAVLVPVVDD
CCCCCCHHHHHHHHHHHCCCCCCHHHCCCCCEEECCCCHHHHHHHCCCCCEEEEEEECC
GDDASVIFTQRTSNLRKHSGQVAFPGGAVDPEDLSIEVAAIREAEEEIGLDPRFVETVAR
CCCCEEEEECCHHHHHHHCCCEECCCCCCCCCCCEEEEHHHHHHHHHHCCCHHHHHHHHH
LPHYMAMSGFRITPVLAVVQPGFVLEPNPQEVESVFDVPLSFLMNPQNHERGSSHWQGAE
CHHHHHHCCCCHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHH
RHFYRMPYGERNIWGITAGIVRMLYERLYA
HHEEECCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA