Click here to switch to the map view.

The map label for this gene is blh [H]

Identifier: 150396819

GI number: 150396819

Start: 1704197

End: 1705087

Strand: Reverse

Name: blh [H]

Synonym: Smed_1610

Alternate gene names: 150396819

Gene position: 1705087-1704197 (Counterclockwise)

Preceding gene: 150396820

Following gene: 150396818

Centisome position: 45.09

GC content: 60.38

Gene sequence:

>891_bases
ATGGCTGCAGATGCAGCGGCACGACCAAGCGTCAAAGGCTTCTATGAAGCGCGCTCGGGAAGCATCCAATACGTCGTTGC
AGATCCGGTGACGAGGCGCTGTGCGATCATCGACCCGGTGCTCGATTTCGACGAGAAGTCGGGATCGATCGAGACCCGGC
AGGCGGAGCTCATCCTCGATCATGTCAAAAGGAACGAGCTGACGGTCGAGTGGATCCTCGACACTCATCCCCATGCGGAC
CATTTTTCTGCTGCCGCATATTTGAAGGAAATGACGCGGGCGCCGACCGGTATCGGCTGCGAGGTGGTCCGCGTCCAGAA
CCTCTGGAAAGGGATCTACAACTGGCCGGAGCTTGCAACGGATGGCTCGCAATGGGATCATCTTTTTGCGGACGGAGAGC
AGTTTTCCCTCGGTTCGCTCGAAGGTCGCGTGATCTACTCACCGGGCCACACGCTTGCTTCGATAACCTATGTCATCGGC
GATGCGGCGTTCGTGCACGATACGATCTTCATGCCGGACAGCGGCACCGCGCGTGCCGATTTCCCCGGAGGAGACGCCCG
GCAATTGTGGCGCTCCATAAATACCATTCTCGCATTGCCGGATGAAACCCGGATCTTCACCGGTCATGACTATCGGCCGA
ACGGGCGAGAGCCGCGGTGGGAAAGCACGGTGTACGAGGAGAAGAGCCGCAATTCCCATGTTGTCGGCATGACCGAAGAG
GCTTTCGTCGCGTTGCGCGAGGCGCGTGACAGGACGCTGCCGATGCCCAAGCTGATCCTTCACGCGCTGCAGGTCAACAT
TTGCGGCGGCCGCCTGCCGGAACCGGAGGCCAACGGCGCCCGTTACCTGAAGTTTCCACTGAACGCGCTCAAGGGAGCGG
CGTGGGGCTGA

Upstream 100 bases:

>100_bases
GGATTTCGTTTCGTGGCCGGACAATGGCCGGATAGACGAAACTTAGCAGCAAAAACGACATTCATTATATTTTATCGTAT
ACTTATAATGGAGACCGATC

Downstream 100 bases:

>100_bases
GGTCCTGTCATGGGAACGATTACCAAATTCCGGAACATTCGCCCTTGCATGAGAGAGCGGGCCGACGAGGCCGCGGCACT
GCTCAAGGCGGTTGCAAACG

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MAADAAARPSVKGFYEARSGSIQYVVADPVTRRCAIIDPVLDFDEKSGSIETRQAELILDHVKRNELTVEWILDTHPHAD
HFSAAAYLKEMTRAPTGIGCEVVRVQNLWKGIYNWPELATDGSQWDHLFADGEQFSLGSLEGRVIYSPGHTLASITYVIG
DAAFVHDTIFMPDSGTARADFPGGDARQLWRSINTILALPDETRIFTGHDYRPNGREPRWESTVYEEKSRNSHVVGMTEE
AFVALREARDRTLPMPKLILHALQVNICGGRLPEPEANGARYLKFPLNALKGAAWG

Sequences:

>Translated_296_residues
MAADAAARPSVKGFYEARSGSIQYVVADPVTRRCAIIDPVLDFDEKSGSIETRQAELILDHVKRNELTVEWILDTHPHAD
HFSAAAYLKEMTRAPTGIGCEVVRVQNLWKGIYNWPELATDGSQWDHLFADGEQFSLGSLEGRVIYSPGHTLASITYVIG
DAAFVHDTIFMPDSGTARADFPGGDARQLWRSINTILALPDETRIFTGHDYRPNGREPRWESTVYEEKSRNSHVVGMTEE
AFVALREARDRTLPMPKLILHALQVNICGGRLPEPEANGARYLKFPLNALKGAAWG
>Mature_295_residues
AADAAARPSVKGFYEARSGSIQYVVADPVTRRCAIIDPVLDFDEKSGSIETRQAELILDHVKRNELTVEWILDTHPHADH
FSAAAYLKEMTRAPTGIGCEVVRVQNLWKGIYNWPELATDGSQWDHLFADGEQFSLGSLEGRVIYSPGHTLASITYVIGD
AAFVHDTIFMPDSGTARADFPGGDARQLWRSINTILALPDETRIFTGHDYRPNGREPRWESTVYEEKSRNSHVVGMTEEA
FVALREARDRTLPMPKLILHALQVNICGGRLPEPEANGARYLKFPLNALKGAAWG

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=267, Percent_Identity=29.2134831460674, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17538952, Length=274, Percent_Identity=28.4671532846715, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI221330176, Length=262, Percent_Identity=29.7709923664122, Blast_Score=100, Evalue=9e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 32931; Mature: 32800

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAADAAARPSVKGFYEARSGSIQYVVADPVTRRCAIIDPVLDFDEKSGSIETRQAELILD
CCCCCCCCCCCHHHHHCCCCCEEEEEECCCCCHHEEECHHHCCCCCCCCCCHHHHHHHHH
HVKRNELTVEWILDTHPHADHFSAAAYLKEMTRAPTGIGCEVVRVQNLWKGIYNWPELAT
HHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHCCCCHHCC
DGSQWDHLFADGEQFSLGSLEGRVIYSPGHTLASITYVIGDAAFVHDTIFMPDSGTARAD
CCCCCCCEECCCCEEEECCCCCEEEECCCCCHHHHHHHHCCHHHHEEEEEECCCCCCCCC
FPGGDARQLWRSINTILALPDETRIFTGHDYRPNGREPRWESTVYEEKSRNSHVVGMTEE
CCCCHHHHHHHHHHHEEECCCCCEEEECCCCCCCCCCCCCCHHHHHHHCCCCEEEEECHH
AFVALREARDRTLPMPKLILHALQVNICGGRLPEPEANGARYLKFPLNALKGAAWG
HHHHHHHHHCCCCCHHHHHHHHHHHEECCCCCCCCCCCCCEEEEECHHHHCCCCCC
>Mature Secondary Structure 
AADAAARPSVKGFYEARSGSIQYVVADPVTRRCAIIDPVLDFDEKSGSIETRQAELILD
CCCCCCCCCCHHHHHCCCCCEEEEEECCCCCHHEEECHHHCCCCCCCCCCHHHHHHHHH
HVKRNELTVEWILDTHPHADHFSAAAYLKEMTRAPTGIGCEVVRVQNLWKGIYNWPELAT
HHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHCCCCHHCC
DGSQWDHLFADGEQFSLGSLEGRVIYSPGHTLASITYVIGDAAFVHDTIFMPDSGTARAD
CCCCCCCEECCCCEEEECCCCCEEEECCCCCHHHHHHHHCCHHHHEEEEEECCCCCCCCC
FPGGDARQLWRSINTILALPDETRIFTGHDYRPNGREPRWESTVYEEKSRNSHVVGMTEE
CCCCHHHHHHHHHHHEEECCCCCEEEECCCCCCCCCCCCCCHHHHHHHCCCCEEEEECHH
AFVALREARDRTLPMPKLILHALQVNICGGRLPEPEANGARYLKFPLNALKGAAWG
HHHHHHHHHCCCCCHHHHHHHHHHHEECCCCCCCCCCCCCEEEEECHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]