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The map label for this gene is nahR [H]

Identifier: 150396674

GI number: 150396674

Start: 1543281

End: 1544303

Strand: Direct

Name: nahR [H]

Synonym: Smed_1461

Alternate gene names: 150396674

Gene position: 1543281-1544303 (Clockwise)

Preceding gene: 150396672

Following gene: 150396675

Centisome position: 40.81

GC content: 59.04

Gene sequence:

>1023_bases
ATGATAGATTATCATCGTAACCTGAACAGCATTCAGTTCGCGTGGATTGGCGCAGGATCGACCTCAATCTTCTCAAGGTG
CTGGCAGTTATGTTGGAAGAACGTAGCGTCGCTCGCTGCCGAACGCCTCTTTGTTTCTCCTTCTGCCGTCAGTCACGCGC
TCGCAAGGCTGAGAACGATGTTTTCGGATCCCCTGTTCGTCAGAACGGGAAGCGGGATGCTGCCAACCGCACGTGCACAA
AGCCTGGAGCGCTCGCTGTCGCTTCTGAAAGCGCTGCTGGCCGCCGAGCTGGAAACAGATCGAGTGAGTGCGACAGAGGT
GCCATTCGAACCCGGCGAATCGGTGCGCGACGTTCGAATCGTCTCCCCAGGGGCCCTGGAGCTCTCGCTCCTGCCGACGT
TGGCGACGATGTTGCGAGCGCGGGCGCCGCAGTGGTCGCTCACGATCGAACCGTTCGAGCGGCGCAGCTACGAGACCGAT
CTCGCCACAGGCCGGGTCGACTTCGTCCTTTCGGTCGGAGGCACAACACCCATCGGACAACTCGTCGATGCTGACGTCCT
ATGGGAGGATGAATTCGTTGTCCTGGCCGGTCCGCGCTCGGTGCTTCATGAAGGTTTCGATCGGATTTCGACCGAGCTCT
ACCTGGCGCAGCAACACATCTATCCGCTTCCCTGGCCGACTTCACAGAACTACCTTGATGTAGAGCTCGCTCGAGCCGGC
AGACACCGCAAGATTGCCTTCTCCGTGCCGAGTTATGCCGCCCTGGGTTACGTACTCGATACCACGGACCTCATAGCTTC
GATGCCGGACCGGTCGGCACGAGCCCTGATGTGCTGCCATCCCGATTTGAGGCTCATTCACCTTGACCCTCCCCGAAAGT
CACAGCTTTCCTTGCTTTGGGGTATATCTGCCTTGCGAGAGCCGGCGATTTCGTGGGTCCGAACCATAATTCGAAACGCC
GCAGCCGCATATGACGGCGCCGACGGAGGAACCATCCGGAGCATCAACAGCGATCAAGTCTAG

Upstream 100 bases:

>100_bases
AAGTGTGACCGCAGCGGCCAGCCTAACGCCCTTTGACATGATTTCACCAGTTTGAGGATGTGGTCGAGACGTTATTGCCA
CATCATAAAAACTGAGCCAA

Downstream 100 bases:

>100_bases
ATTACGATGCTTTTAGATCGGATCGACCTAAAAACAGGATTGTGATCGATGCCAATCAACAGATGTCGTGTAGATGCAAA
CGTATCATCGTGGGGCGCGT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MIDYHRNLNSIQFAWIGAGSTSIFSRCWQLCWKNVASLAAERLFVSPSAVSHALARLRTMFSDPLFVRTGSGMLPTARAQ
SLERSLSLLKALLAAELETDRVSATEVPFEPGESVRDVRIVSPGALELSLLPTLATMLRARAPQWSLTIEPFERRSYETD
LATGRVDFVLSVGGTTPIGQLVDADVLWEDEFVVLAGPRSVLHEGFDRISTELYLAQQHIYPLPWPTSQNYLDVELARAG
RHRKIAFSVPSYAALGYVLDTTDLIASMPDRSARALMCCHPDLRLIHLDPPRKSQLSLLWGISALREPAISWVRTIIRNA
AAAYDGADGGTIRSINSDQV

Sequences:

>Translated_340_residues
MIDYHRNLNSIQFAWIGAGSTSIFSRCWQLCWKNVASLAAERLFVSPSAVSHALARLRTMFSDPLFVRTGSGMLPTARAQ
SLERSLSLLKALLAAELETDRVSATEVPFEPGESVRDVRIVSPGALELSLLPTLATMLRARAPQWSLTIEPFERRSYETD
LATGRVDFVLSVGGTTPIGQLVDADVLWEDEFVVLAGPRSVLHEGFDRISTELYLAQQHIYPLPWPTSQNYLDVELARAG
RHRKIAFSVPSYAALGYVLDTTDLIASMPDRSARALMCCHPDLRLIHLDPPRKSQLSLLWGISALREPAISWVRTIIRNA
AAAYDGADGGTIRSINSDQV
>Mature_340_residues
MIDYHRNLNSIQFAWIGAGSTSIFSRCWQLCWKNVASLAAERLFVSPSAVSHALARLRTMFSDPLFVRTGSGMLPTARAQ
SLERSLSLLKALLAAELETDRVSATEVPFEPGESVRDVRIVSPGALELSLLPTLATMLRARAPQWSLTIEPFERRSYETD
LATGRVDFVLSVGGTTPIGQLVDADVLWEDEFVVLAGPRSVLHEGFDRISTELYLAQQHIYPLPWPTSQNYLDVELARAG
RHRKIAFSVPSYAALGYVLDTTDLIASMPDRSARALMCCHPDLRLIHLDPPRKSQLSLLWGISALREPAISWVRTIIRNA
AAAYDGADGGTIRSINSDQV

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790147, Length=305, Percent_Identity=27.5409836065574, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081766, Length=290, Percent_Identity=25.5172413793103, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 37572; Mature: 37572

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDYHRNLNSIQFAWIGAGSTSIFSRCWQLCWKNVASLAAERLFVSPSAVSHALARLRTM
CCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
FSDPLFVRTGSGMLPTARAQSLERSLSLLKALLAAELETDRVSATEVPFEPGESVRDVRI
HCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEE
VSPGALELSLLPTLATMLRARAPQWSLTIEPFERRSYETDLATGRVDFVLSVGGTTPIGQ
ECCCCEEEHHHHHHHHHHHHCCCCCEEEECHHHCCCCCCCCCCCCEEEEEECCCCCCHHH
LVDADVLWEDEFVVLAGPRSVLHEGFDRISTELYLAQQHIYPLPWPTSQNYLDVELARAG
HHCCCEEECCCEEEEECCHHHHHHHHHHHHHHHEEHHHCCCCCCCCCCCCEEEEEHHCCC
RHRKIAFSVPSYAALGYVLDTTDLIASMPDRSARALMCCHPDLRLIHLDPPRKSQLSLLW
CCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEECCCCCHHHHHHH
GISALREPAISWVRTIIRNAAAAYDGADGGTIRSINSDQV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCC
>Mature Secondary Structure
MIDYHRNLNSIQFAWIGAGSTSIFSRCWQLCWKNVASLAAERLFVSPSAVSHALARLRTM
CCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
FSDPLFVRTGSGMLPTARAQSLERSLSLLKALLAAELETDRVSATEVPFEPGESVRDVRI
HCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEE
VSPGALELSLLPTLATMLRARAPQWSLTIEPFERRSYETDLATGRVDFVLSVGGTTPIGQ
ECCCCEEEHHHHHHHHHHHHCCCCCEEEECHHHCCCCCCCCCCCCEEEEEECCCCCCHHH
LVDADVLWEDEFVVLAGPRSVLHEGFDRISTELYLAQQHIYPLPWPTSQNYLDVELARAG
HHCCCEEECCCEEEEECCHHHHHHHHHHHHHHHEEHHHCCCCCCCCCCCCEEEEEHHCCC
RHRKIAFSVPSYAALGYVLDTTDLIASMPDRSARALMCCHPDLRLIHLDPPRKSQLSLLW
CCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEECCCCCHHHHHHH
GISALREPAISWVRTIIRNAAAAYDGADGGTIRSINSDQV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]