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The map label for this gene is trkA [H]

Identifier: 150396312

GI number: 150396312

Start: 1163153

End: 1164529

Strand: Direct

Name: trkA [H]

Synonym: Smed_1093

Alternate gene names: 150396312

Gene position: 1163153-1164529 (Clockwise)

Preceding gene: 150396311

Following gene: 150396313

Centisome position: 30.76

GC content: 61.58

Gene sequence:

>1377_bases
ATGAAGGTGATCATATGCGGGGCAGGTCAGGTCGGCTACGGGATCGCCGAGCGGCTGTCGCGCGAGAATAACGACGTTTC
GGTGATCGATACGTCCGCCGCGCTGATTGCCTCTATAACCGAGGCGCTGGACGTGCGCGGTTACGTCGGTCACGGGGCAC
ATCCGGACGTGTTGGCAAAGGCTGGGGCCGACCAGGCCGATATGTTGATCGCTGTGACACTTTATGACGAAGTCAACATC
GTCGCATGCGAAGTGGCGCATGCGATCTTCAACGTTCCGACCAAGGTCGCCCGCATCCGCGCGCAGAGCTATCTTGCGCC
GGAATATTCCGATCTCTTTTCGCGCGAGAACGTTCCGATCGACGTCACGATCTCTCCGGAGATAGAGGTAGGGCGGCTTG
TGCTTCGCCGCATTTCCTTTCCGGGCGCGACCGACGTGGTGCGCTTCGCGGATGACCGGATCGCGATGGTTGCGATCGAG
TGCATGGAAGATTGCCCCGTCGTCGACACGCCTTTGCAGCAGCTCAGCGAGCTCTTCCCCGATCTCCACGCGACGGTCAC
CGGTATCTTCCGGGACGGCGAACTGATCGTCCCGCATTCGTCCGACCAGTTGAAGACCGGCGATCTGGCCTATGTCGTCT
GCGACCGGGACCATGCCCGTCGCACGCTGGCGCTCTTCGGGCACGAAGAACAGGAGGCGCGGCGCATCATCATCCTGGGC
GCCGGTAACATCGGCTATTTCGTCGCCCGGATGATCGAAGAGCAGCAGCCGCGCATGCGGGTGAAGCTCATCGAGAACGA
TCGCGATCGCGCGGTGCTTGTCGCCGACAAGCTCAACAACACGGTCGTCCTCCACGGCTCGGCGATGGACCAGCGGATTC
TGGCGCAAGCGGATGTCCAGGAGGCGGATCTGGTCGTCGCGCTGACGAACAACGACCAGATCAACATCCTCGGCAGCATG
CTTGCAAGGAAGCAGGGTGCGAAATCGGCCCTGGTGCTGATCAATGAGCCGGCCTATCAGGACTTCGCCGGCGCCGCCGG
CGTCGACGCGTATATCAATCCGCGCGCAGTCACCATATCGCGCGTGTTGCAGCATGTCCGAAAGGGTCGTATCCGGTCGG
TCTACGCGGTTCAGAACGGTATGGCGGAGGTCATCGAGGCCGAAGCGCTCGAAACCTCTCCCTTGGTCGGCAAGGCGCTG
CGCGAACTCGAATTGCCCGACGGTATACGCATCGGCGCGCTTTATCGCGACAAGGCCTATGTTCGTCCCGATGGCGACAC
GCGGATCAAGGCCAAGGATCGCGTGGTACTGCTGGCGGCCGCCGAGACCGTCCGTCATGTCGAACAGCTCTTCCGCGTCA
GCATTCAATATTTCTGA

Upstream 100 bases:

>100_bases
GCTCTTCATCGCAAGCTGAAGTCGCTCGGCGTGTGATTATCCCGGTCGTGAATTCAATTTTCGGGCCAGCCGCAGAACCG
GCCAGACATAAGGAACAGCC

Downstream 100 bases:

>100_bases
GGGACTCAGCCATGCCGAGAATCGCCTATGTCAACGGCACTTATGTCCGGCACGCCGAGGCCGCCATTCACGTCGAGGAT
CGGGGCTATCAGTTTGCCGA

Product: potassium transporter peripheral membrane protein

Products: NA

Alternate protein names: K(+)-uptake protein trkA [H]

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MKVIICGAGQVGYGIAERLSRENNDVSVIDTSAALIASITEALDVRGYVGHGAHPDVLAKAGADQADMLIAVTLYDEVNI
VACEVAHAIFNVPTKVARIRAQSYLAPEYSDLFSRENVPIDVTISPEIEVGRLVLRRISFPGATDVVRFADDRIAMVAIE
CMEDCPVVDTPLQQLSELFPDLHATVTGIFRDGELIVPHSSDQLKTGDLAYVVCDRDHARRTLALFGHEEQEARRIIILG
AGNIGYFVARMIEEQQPRMRVKLIENDRDRAVLVADKLNNTVVLHGSAMDQRILAQADVQEADLVVALTNNDQINILGSM
LARKQGAKSALVLINEPAYQDFAGAAGVDAYINPRAVTISRVLQHVRKGRIRSVYAVQNGMAEVIEAEALETSPLVGKAL
RELELPDGIRIGALYRDKAYVRPDGDTRIKAKDRVVLLAAAETVRHVEQLFRVSIQYF

Sequences:

>Translated_458_residues
MKVIICGAGQVGYGIAERLSRENNDVSVIDTSAALIASITEALDVRGYVGHGAHPDVLAKAGADQADMLIAVTLYDEVNI
VACEVAHAIFNVPTKVARIRAQSYLAPEYSDLFSRENVPIDVTISPEIEVGRLVLRRISFPGATDVVRFADDRIAMVAIE
CMEDCPVVDTPLQQLSELFPDLHATVTGIFRDGELIVPHSSDQLKTGDLAYVVCDRDHARRTLALFGHEEQEARRIIILG
AGNIGYFVARMIEEQQPRMRVKLIENDRDRAVLVADKLNNTVVLHGSAMDQRILAQADVQEADLVVALTNNDQINILGSM
LARKQGAKSALVLINEPAYQDFAGAAGVDAYINPRAVTISRVLQHVRKGRIRSVYAVQNGMAEVIEAEALETSPLVGKAL
RELELPDGIRIGALYRDKAYVRPDGDTRIKAKDRVVLLAAAETVRHVEQLFRVSIQYF
>Mature_458_residues
MKVIICGAGQVGYGIAERLSRENNDVSVIDTSAALIASITEALDVRGYVGHGAHPDVLAKAGADQADMLIAVTLYDEVNI
VACEVAHAIFNVPTKVARIRAQSYLAPEYSDLFSRENVPIDVTISPEIEVGRLVLRRISFPGATDVVRFADDRIAMVAIE
CMEDCPVVDTPLQQLSELFPDLHATVTGIFRDGELIVPHSSDQLKTGDLAYVVCDRDHARRTLALFGHEEQEARRIIILG
AGNIGYFVARMIEEQQPRMRVKLIENDRDRAVLVADKLNNTVVLHGSAMDQRILAQADVQEADLVVALTNNDQINILGSM
LARKQGAKSALVLINEPAYQDFAGAAGVDAYINPRAVTISRVLQHVRKGRIRSVYAVQNGMAEVIEAEALETSPLVGKAL
RELELPDGIRIGALYRDKAYVRPDGDTRIKAKDRVVLLAAAETVRHVEQLFRVSIQYF

Specific function: Part of a potassium transport system [H]

COG id: COG0569

COG function: function code P; K+ transport systems, NAD-binding component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 RCK N-terminal domains [H]

Homologues:

Organism=Escherichia coli, GI1789685, Length=458, Percent_Identity=39.7379912663755, Blast_Score=324, Evalue=7e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006036
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 50250; Mature: 50250

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVIICGAGQVGYGIAERLSRENNDVSVIDTSAALIASITEALDVRGYVGHGAHPDVLAK
CEEEEECCCCCCHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
AGADQADMLIAVTLYDEVNIVACEVAHAIFNVPTKVARIRAQSYLAPEYSDLFSRENVPI
CCCCCCCEEEEEEEECCCCEEHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHCCCCCCE
DVTISPEIEVGRLVLRRISFPGATDVVRFADDRIAMVAIECMEDCPVVDTPLQQLSELFP
EEEECCCCHHHHHHHHHCCCCCCCCHHEECCCCEEEEEEEHHHCCCCCCCHHHHHHHHCC
DLHATVTGIFRDGELIVPHSSDQLKTGDLAYVVCDRDHARRTLALFGHEEQEARRIIILG
HHHHEEEEEEECCCEEECCCCCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCCEEEEEE
AGNIGYFVARMIEEQQPRMRVKLIENDRDRAVLVADKLNNTVVLHGSAMDQRILAQADVQ
CCCHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCCCEEEEECCCCCHHHHHHCCCC
EADLVVALTNNDQINILGSMLARKQGAKSALVLINEPAYQDFAGAAGVDAYINPRAVTIS
CCCEEEEEECCCCCHHHHHHHHHHCCCCEEEEEEECCCCHHHCCCCCCCCEECCCEEHHH
RVLQHVRKGRIRSVYAVQNGMAEVIEAEALETSPLVGKALRELELPDGIRIGALYRDKAY
HHHHHHHCCCCEEEEHHHHCHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEEEEEECCEE
VRPDGDTRIKAKDRVVLLAAAETVRHVEQLFRVSIQYF
ECCCCCCEEEECCCEEEEEHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKVIICGAGQVGYGIAERLSRENNDVSVIDTSAALIASITEALDVRGYVGHGAHPDVLAK
CEEEEECCCCCCHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
AGADQADMLIAVTLYDEVNIVACEVAHAIFNVPTKVARIRAQSYLAPEYSDLFSRENVPI
CCCCCCCEEEEEEEECCCCEEHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHCCCCCCE
DVTISPEIEVGRLVLRRISFPGATDVVRFADDRIAMVAIECMEDCPVVDTPLQQLSELFP
EEEECCCCHHHHHHHHHCCCCCCCCHHEECCCCEEEEEEEHHHCCCCCCCHHHHHHHHCC
DLHATVTGIFRDGELIVPHSSDQLKTGDLAYVVCDRDHARRTLALFGHEEQEARRIIILG
HHHHEEEEEEECCCEEECCCCCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCCEEEEEE
AGNIGYFVARMIEEQQPRMRVKLIENDRDRAVLVADKLNNTVVLHGSAMDQRILAQADVQ
CCCHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCCCEEEEECCCCCHHHHHHCCCC
EADLVVALTNNDQINILGSMLARKQGAKSALVLINEPAYQDFAGAAGVDAYINPRAVTIS
CCCEEEEEECCCCCHHHHHHHHHHCCCCEEEEEEECCCCHHHCCCCCCCCEECCCEEHHH
RVLQHVRKGRIRSVYAVQNGMAEVIEAEALETSPLVGKALRELELPDGIRIGALYRDKAY
HHHHHHHCCCCEEEEHHHHCHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEEEEEECCEE
VRPDGDTRIKAKDRVVLLAAAETVRHVEQLFRVSIQYF
ECCCCCCEEEECCCEEEEEHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]