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The map label for this gene is 150395657

Identifier: 150395657

GI number: 150395657

Start: 467665

End: 469209

Strand: Direct

Name: 150395657

Synonym: Smed_0432

Alternate gene names: NA

Gene position: 467665-469209 (Clockwise)

Preceding gene: 150395655

Following gene: 150395664

Centisome position: 12.37

GC content: 61.1

Gene sequence:

>1545_bases
ATGGAACTGGCTGAAGCAACCGGTGAGGCGCCGAGACGAACCCGGAGCGGGCGACCGCAGCGGCGCGAAGGCACCAAGAA
ACTCGGTGTCCCCTACATCGTCCGCAATATACCGGCCTATGACATCCTCGGCGAAGAAAATCTGGAGCGGATCGAGCGGG
TCGCCGACCGAATTCTTGCCGAAGTCGGCATCGAGTTTCGCGACGATCCGGTAGCACTCGAGCACTGGCGGGGTGCCGGT
GCGAAAATAGACGGTCTGCGCGTCACCTTCGAACCCGGCATGCTGAAGGAGATCGTCCGCTCGGCGCCGTCCCAATTCAC
GCAGCACGCCCGCAATCCGGCGCGCAGCGTCGAGATCGGCGGCCGAAACGTCGTATTCTCACCGGCTTACGGCTCACCCT
TCGTCATGGATCTGGATAAAGGCAGGCGCTACGGCACCATCGAGGATTTCCGCAATCTGGTGAAGCTCGCCCAGTCGAGC
CCATGGCTGCACCACTCCGGCGGCACCATCTGCGAACCGGTCGACGTGCCGGTAAACAAGCGCCATCTCGATATGGTCTA
CAGCCACGTCAGATATTCGGACCGTGCCTTCATGGGCTCGATCACCTCGGAAGAACGAGCCGAAGATTCGATCGAAATGG
CGCGCATCCTTTTCGGTGCCGATTTCGTGGACAGGAACTGCGTCATACTCGGTAACGTCAACGTCAACTCGCCGCTCGTC
TGGGACGGCACCATGACGAAGTCGCTGCGTGCCTATGCTCGTGCGAACCAGGCTGCGGTGATCGTACCGTTCATCCTCGG
CGGAGCGATGGGCCCGGTAACCAATGCGGGGGCGATTGCACAATCCTATGCCGAAACGCTTGCCGGCTGCGCGCTGACGC
AGCTCGAACGCAAGGGTGCGCCCGTCATATTCGGGAATTTTCTATCCTCCATGTCGCTCCGCTCCGGCTCGCCAACCTTC
GGTACGCCGGAGCCGGCGATCGGCAGCATGGTCGTCGGACAGCTCGCGCGCCGGCTCGGTCTGCCGTTGCGCTGCGCCGG
CAATTTCTCCAACTCGAAACGGCCCGATGCTCAGGCCATGCAGGAAGGGGTCATGTCGATGCTGTCGGCGGTCCATTGCG
GCGCCAATTTCGTCCTGCATTCGGCCGGCTTCGCCGACGGCCTGCTGGCGATGTCCTATGAGAAATTCATGATGGATATG
GATTTCTGCGGGGCGCTGCATTCCTACCTTGCTGGGGTGGTGATCGACGACAATACGCTCGCCATGGACGCTTTCCTGGA
GGTCGGCCCCGGCAGCCACTTCCTTGGCTGCGAGCACACGATGCGCAATTACCAGACTGCGTTCTGGGACAGTTCCCTTT
CCGACAACGAGCCCTTCGAGAAATGGGTCGAGCAGGGCGAGACGGACATGGCGCTTCGCGCCAACAGAAGCTGGAAGAAG
GCACTGGCGGAATATGAAGCGCCGCCTCTGGATATGGCGATCGACGATGCGTTGATTGACTATGTTGAAAGACGGAAGGG
CGAAATGCCCGATGCGTGGTACTAG

Upstream 100 bases:

>100_bases
GTTTTCCATAAGTACCATTTATATCATGCGTCGAATTTTTCCTGCGTTACAACAGCCTCTCTCGTCAATACCATCATCGC
AAATGATGGGAGAGTTGATC

Downstream 100 bases:

>100_bases
AGCGGAAAACTACGTGGGGGTTTCTGTCCGCATCGCGTGTCTTGAAGGCTCAAAAAAAGAGCGGCGCAATAAGCGCCGCT
CCTGTTGACCCGTTACAGTG

Product: trimethylamine methyltransferase

Products: NA

Alternate protein names: TMA methyltransferase [H]

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MELAEATGEAPRRTRSGRPQRREGTKKLGVPYIVRNIPAYDILGEENLERIERVADRILAEVGIEFRDDPVALEHWRGAG
AKIDGLRVTFEPGMLKEIVRSAPSQFTQHARNPARSVEIGGRNVVFSPAYGSPFVMDLDKGRRYGTIEDFRNLVKLAQSS
PWLHHSGGTICEPVDVPVNKRHLDMVYSHVRYSDRAFMGSITSEERAEDSIEMARILFGADFVDRNCVILGNVNVNSPLV
WDGTMTKSLRAYARANQAAVIVPFILGGAMGPVTNAGAIAQSYAETLAGCALTQLERKGAPVIFGNFLSSMSLRSGSPTF
GTPEPAIGSMVVGQLARRLGLPLRCAGNFSNSKRPDAQAMQEGVMSMLSAVHCGANFVLHSAGFADGLLAMSYEKFMMDM
DFCGALHSYLAGVVIDDNTLAMDAFLEVGPGSHFLGCEHTMRNYQTAFWDSSLSDNEPFEKWVEQGETDMALRANRSWKK
ALAEYEAPPLDMAIDDALIDYVERRKGEMPDAWY

Sequences:

>Translated_514_residues
MELAEATGEAPRRTRSGRPQRREGTKKLGVPYIVRNIPAYDILGEENLERIERVADRILAEVGIEFRDDPVALEHWRGAG
AKIDGLRVTFEPGMLKEIVRSAPSQFTQHARNPARSVEIGGRNVVFSPAYGSPFVMDLDKGRRYGTIEDFRNLVKLAQSS
PWLHHSGGTICEPVDVPVNKRHLDMVYSHVRYSDRAFMGSITSEERAEDSIEMARILFGADFVDRNCVILGNVNVNSPLV
WDGTMTKSLRAYARANQAAVIVPFILGGAMGPVTNAGAIAQSYAETLAGCALTQLERKGAPVIFGNFLSSMSLRSGSPTF
GTPEPAIGSMVVGQLARRLGLPLRCAGNFSNSKRPDAQAMQEGVMSMLSAVHCGANFVLHSAGFADGLLAMSYEKFMMDM
DFCGALHSYLAGVVIDDNTLAMDAFLEVGPGSHFLGCEHTMRNYQTAFWDSSLSDNEPFEKWVEQGETDMALRANRSWKK
ALAEYEAPPLDMAIDDALIDYVERRKGEMPDAWY
>Mature_514_residues
MELAEATGEAPRRTRSGRPQRREGTKKLGVPYIVRNIPAYDILGEENLERIERVADRILAEVGIEFRDDPVALEHWRGAG
AKIDGLRVTFEPGMLKEIVRSAPSQFTQHARNPARSVEIGGRNVVFSPAYGSPFVMDLDKGRRYGTIEDFRNLVKLAQSS
PWLHHSGGTICEPVDVPVNKRHLDMVYSHVRYSDRAFMGSITSEERAEDSIEMARILFGADFVDRNCVILGNVNVNSPLV
WDGTMTKSLRAYARANQAAVIVPFILGGAMGPVTNAGAIAQSYAETLAGCALTQLERKGAPVIFGNFLSSMSLRSGSPTF
GTPEPAIGSMVVGQLARRLGLPLRCAGNFSNSKRPDAQAMQEGVMSMLSAVHCGANFVLHSAGFADGLLAMSYEKFMMDM
DFCGALHSYLAGVVIDDNTLAMDAFLEVGPGSHFLGCEHTMRNYQTAFWDSSLSDNEPFEKWVEQGETDMALRANRSWKK
ALAEYEAPPLDMAIDDALIDYVERRKGEMPDAWY

Specific function: Catalyzes probably the transfer of a methyl group from trimethylamine to the corrinoid cofactor of mttC [H]

COG id: COG5598

COG function: function code H; Trimethylamine:corrinoid methyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trimethylamine methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010426 [H]

Pfam domain/function: PF06253 MTTB [H]

EC number: NA

Molecular weight: Translated: 56574; Mature: 56574

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELAEATGEAPRRTRSGRPQRREGTKKLGVPYIVRNIPAYDILGEENLERIERVADRILA
CCCHHHCCCCCHHHCCCCCHHHCCCHHCCCCHHHHCCCCHHCCCHHHHHHHHHHHHHHHH
EVGIEFRDDPVALEHWRGAGAKIDGLRVTFEPGMLKEIVRSAPSQFTQHARNPARSVEIG
HHCCCCCCCCCHHHHHCCCCCEECCEEEEECCHHHHHHHHHCHHHHHHHHCCCCCEEEEC
GRNVVFSPAYGSPFVMDLDKGRRYGTIEDFRNLVKLAQSSPWLHHSGGTICEPVDVPVNK
CCEEEEECCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCEECCCCCEECCCCCCCCH
RHLDMVYSHVRYSDRAFMGSITSEERAEDSIEMARILFGADFVDRNCVILGNVNVNSPLV
HHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCEE
WDGTMTKSLRAYARANQAAVIVPFILGGAMGPVTNAGAIAQSYAETLAGCALTQLERKGA
ECCHHHHHHHHHHHCCCCEEEHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
PVIFGNFLSSMSLRSGSPTFGTPEPAIGSMVVGQLARRLGLPLRCAGNFSNSKRPDAQAM
CEEEHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCHHHH
QEGVMSMLSAVHCGANFVLHSAGFADGLLAMSYEKFMMDMDFCGALHSYLAGVVIDDNTL
HHHHHHHHHHHHCCCHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCE
AMDAFLEVGPGSHFLGCEHTMRNYQTAFWDSSLSDNEPFEKWVEQGETDMALRANRSWKK
EEHHHHCCCCCCCEECHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCEEHHCCCHHHH
ALAEYEAPPLDMAIDDALIDYVERRKGEMPDAWY
HHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MELAEATGEAPRRTRSGRPQRREGTKKLGVPYIVRNIPAYDILGEENLERIERVADRILA
CCCHHHCCCCCHHHCCCCCHHHCCCHHCCCCHHHHCCCCHHCCCHHHHHHHHHHHHHHHH
EVGIEFRDDPVALEHWRGAGAKIDGLRVTFEPGMLKEIVRSAPSQFTQHARNPARSVEIG
HHCCCCCCCCCHHHHHCCCCCEECCEEEEECCHHHHHHHHHCHHHHHHHHCCCCCEEEEC
GRNVVFSPAYGSPFVMDLDKGRRYGTIEDFRNLVKLAQSSPWLHHSGGTICEPVDVPVNK
CCEEEEECCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCEECCCCCEECCCCCCCCH
RHLDMVYSHVRYSDRAFMGSITSEERAEDSIEMARILFGADFVDRNCVILGNVNVNSPLV
HHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCEE
WDGTMTKSLRAYARANQAAVIVPFILGGAMGPVTNAGAIAQSYAETLAGCALTQLERKGA
ECCHHHHHHHHHHHCCCCEEEHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
PVIFGNFLSSMSLRSGSPTFGTPEPAIGSMVVGQLARRLGLPLRCAGNFSNSKRPDAQAM
CEEEHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCHHHH
QEGVMSMLSAVHCGANFVLHSAGFADGLLAMSYEKFMMDMDFCGALHSYLAGVVIDDNTL
HHHHHHHHHHHHCCCHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCE
AMDAFLEVGPGSHFLGCEHTMRNYQTAFWDSSLSDNEPFEKWVEQGETDMALRANRSWKK
EEHHHHCCCCCCCEECHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCEEHHCCCHHHH
ALAEYEAPPLDMAIDDALIDYVERRKGEMPDAWY
HHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA