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The map label for this gene is dppC [H]

Identifier: 150395557

GI number: 150395557

Start: 361683

End: 362591

Strand: Direct

Name: dppC [H]

Synonym: Smed_0331

Alternate gene names: 150395557

Gene position: 361683-362591 (Clockwise)

Preceding gene: 150395556

Following gene: 150395558

Centisome position: 9.56

GC content: 63.48

Gene sequence:

>909_bases
ATGACCGAAGCTACCGCAACCACCGCCATATCGGCCGATCCGACGCGCCGGGCGCGCCTCGCCGAATTCTGGTATTATTT
CTCGGAGAACCGCGGCGCCGTCTTCGGCCTGTTCTTCTTCCTGTTCCTGGTGCTGCTCGCCATCTTCGCACCGCTCGTGG
CGCCGCATAACCCGACCATCCAGTTCGGCGACGCGCGACTGGTCCCGCCGGTCTGGCAGGAAGGTGGCCGCGCGACATTC
CTGCTCGGCACCGATGCCGTCGGCCGCGACATGCTCTCCCGTCTCATTTATGGAACACGCTTCTCACTCTTTATCGGCGT
TATCGTTACGGTCTTGTCTTTGACCGGCGGCATTCTGGTCGGCGTCATCGCCGGTTATTTCCGCGGATGGATCGACACGG
TCATCATGCGGCTGATGGACATCATCCTGGCTTTCCCGTCGCTCCTTCTGGCGCTTGTCCTCGTGGCGGTGCTGGGACCT
GGCCTTACCAATGCGATGATCGCGATCGCACTGGTCTTCCAGCCGCATTTCGTCCGTCTGACCCGAGCGGCGGTGATGAC
GGAGAAGACGCGCGATTACGTCGTGGCGGCGAAGGTCGCCGGAGCAGGCCATGCGAGGCTCATGTTCAAGACGATCCTGC
CGAACTGCATGGCGCCGCTCATCGTTCAGGCGACGCTGTCTTTCTCGAACGCGATCCTCGACGCGGCGGCGCTCGGCTTC
CTGGGCATGGGGGCGCAGCCGCCGACGCCGGAATGGGGAACCATGCTTGCGGAAGCACGCGAGTTCATCCTGCGTGCCTG
GTGGGTCGTCACGCTTCCGGGCCTCGCCATCCTGGTGACCGTCCTGGCCATCAATCTGATGGGCGATGGCCTGCGCGACG
CTCTCGATCCGAAGCTGAAGAGGTCCTGA

Upstream 100 bases:

>100_bases
GGGCTTCTGATCATCGCCGCGGTGATCATGCTGGTGAACCTCGCCGTGGATCTGCTCTACGGCCTGATCAATCCGCGCAT
CCGGCACTGAGGAGGGCGAT

Downstream 100 bases:

>100_bases
CATGGCGCTTCTCGAAATCGAAAATCTCGTCGTCGAATTCCAGACGGCGTCCGGGCCCTTCCGGGCGGTAGACGGCGTGT
CGCTCAAGGTGCATGAGAGC

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MTEATATTAISADPTRRARLAEFWYYFSENRGAVFGLFFFLFLVLLAIFAPLVAPHNPTIQFGDARLVPPVWQEGGRATF
LLGTDAVGRDMLSRLIYGTRFSLFIGVIVTVLSLTGGILVGVIAGYFRGWIDTVIMRLMDIILAFPSLLLALVLVAVLGP
GLTNAMIAIALVFQPHFVRLTRAAVMTEKTRDYVVAAKVAGAGHARLMFKTILPNCMAPLIVQATLSFSNAILDAAALGF
LGMGAQPPTPEWGTMLAEAREFILRAWWVVTLPGLAILVTVLAINLMGDGLRDALDPKLKRS

Sequences:

>Translated_302_residues
MTEATATTAISADPTRRARLAEFWYYFSENRGAVFGLFFFLFLVLLAIFAPLVAPHNPTIQFGDARLVPPVWQEGGRATF
LLGTDAVGRDMLSRLIYGTRFSLFIGVIVTVLSLTGGILVGVIAGYFRGWIDTVIMRLMDIILAFPSLLLALVLVAVLGP
GLTNAMIAIALVFQPHFVRLTRAAVMTEKTRDYVVAAKVAGAGHARLMFKTILPNCMAPLIVQATLSFSNAILDAAALGF
LGMGAQPPTPEWGTMLAEAREFILRAWWVVTLPGLAILVTVLAINLMGDGLRDALDPKLKRS
>Mature_301_residues
TEATATTAISADPTRRARLAEFWYYFSENRGAVFGLFFFLFLVLLAIFAPLVAPHNPTIQFGDARLVPPVWQEGGRATFL
LGTDAVGRDMLSRLIYGTRFSLFIGVIVTVLSLTGGILVGVIAGYFRGWIDTVIMRLMDIILAFPSLLLALVLVAVLGPG
LTNAMIAIALVFQPHFVRLTRAAVMTEKTRDYVVAAKVAGAGHARLMFKTILPNCMAPLIVQATLSFSNAILDAAALGFL
GMGAQPPTPEWGTMLAEAREFILRAWWVVTLPGLAILVTVLAINLMGDGLRDALDPKLKRS

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789964, Length=301, Percent_Identity=63.7873754152824, Blast_Score=333, Evalue=1e-92,
Organism=Escherichia coli, GI1787760, Length=298, Percent_Identity=41.6107382550336, Blast_Score=223, Evalue=1e-59,
Organism=Escherichia coli, GI1787054, Length=279, Percent_Identity=41.9354838709677, Blast_Score=219, Evalue=1e-58,
Organism=Escherichia coli, GI1787549, Length=272, Percent_Identity=41.9117647058824, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI1789889, Length=249, Percent_Identity=39.3574297188755, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1787498, Length=272, Percent_Identity=31.6176470588235, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1788505, Length=219, Percent_Identity=30.5936073059361, Blast_Score=104, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32736; Mature: 32605

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEATATTAISADPTRRARLAEFWYYFSENRGAVFGLFFFLFLVLLAIFAPLVAPHNPTI
CCCCCCCEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCE
QFGDARLVPPVWQEGGRATFLLGTDAVGRDMLSRLIYGTRFSLFIGVIVTVLSLTGGILV
EECCCCCCCHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVIAGYFRGWIDTVIMRLMDIILAFPSLLLALVLVAVLGPGLTNAMIAIALVFQPHFVRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
TRAAVMTEKTRDYVVAAKVAGAGHARLMFKTILPNCMAPLIVQATLSFSNAILDAAALGF
HHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGMGAQPPTPEWGTMLAEAREFILRAWWVVTLPGLAILVTVLAINLMGDGLRDALDPKLK
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCC
RS
CC
>Mature Secondary Structure 
TEATATTAISADPTRRARLAEFWYYFSENRGAVFGLFFFLFLVLLAIFAPLVAPHNPTI
CCCCCCEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCE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CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800; 8550458 [H]