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The map label for this gene is dppB [H]

Identifier: 150395556

GI number: 150395556

Start: 360668

End: 361672

Strand: Direct

Name: dppB [H]

Synonym: Smed_0330

Alternate gene names: 150395556

Gene position: 360668-361672 (Clockwise)

Preceding gene: 150395555

Following gene: 150395557

Centisome position: 9.54

GC content: 62.39

Gene sequence:

>1005_bases
ATGTTCCGATTCTTTCTGGGGCGCTTGGCAGTGCTGATCCCGACCTTCATCGGGGTTTCCATCATCGCCTTCTCCTTCAT
TCGTCTGCTTCCCGGCGACCCGGTGGCGCTGCTTTCCGGTGAACGGGTGATGTCGCCGGAGCGGCACGCCGAAATTTCTC
GCCAGCTGGGCTTCGACCGCCCGATCGTCATGCAGTACCTGGATTATCTCTGGGGCGTTCTGCAGGGCGATTTCGGCACG
TCGATCGTCACCAAGAGGCCGGTGATGGATCAGTTCCTGGAGCTCTTCCCGGCAACCGTCGAACTGTCGCTCTGCGCCAT
CATTTTCGCCGTCCTTGTCGGTATTCCCGCCGGTGTCGTCGCGGCGGTCAAGCGCGGGTCCATCTTCGACCAGATCATCA
TGGGCACCGCGCTCGTCGGCTTCTCGATGCCGATTTTCTGGTGGGGCCTGCTGCTGATCATGCTTGTCTCCGGTACGCTG
CAATGGACGCCGGTGTCCGGCCGGATTTCGCTGATGTTCTACTTCCCCTCAGTCACCGGCTTCATGCTGATCGACTCGCT
TTTGTCGGGACAGGAAGGTGCGTTCCGGTCGGCCCTCCACCACCTTATTCTGCCGACGATCGTACTCGGCACCATTCCGC
TCGCCGTCATCGCGCGCCAGACCCGCTCGGCAATGCTCGAGGTACTTTCCGAGGACTATGTCCGCACCGCGCGCGCCAAA
GGGCTCTCCACCTTCCGGGTGGTCGGCATCCACGCGCTGCGCAATGCGATGATCCCCGTCGTCACCACCATCGGCCTGCA
GATCGGCGTGATGCTGGCGGGCGCGATCCTGACGGAGACGATCTTCTCCTGGCCGGGGATCGGCAAATGGCTGCTCGATT
CGGTGTCCCGGCGCGACTATGCCGTCATCCAGGGCGGGCTTCTGATCATCGCCGCGGTGATCATGCTGGTGAACCTCGCC
GTGGATCTGCTCTACGGCCTGATCAATCCGCGCATCCGGCACTGA

Upstream 100 bases:

>100_bases
ATCGACTGATCCGAAGGGGGCGTTTGCCGCTGGCGAGCGCCCCTCTTCCTTTTTGCCAGTGCCGCCCCTTCTGCGGCCAC
CTTCGGCATGAGGTTTGACT

Downstream 100 bases:

>100_bases
GGAGGGCGATATGACCGAAGCTACCGCAACCACCGCCATATCGGCCGATCCGACGCGCCGGGCGCGCCTCGCCGAATTCT
GGTATTATTTCTCGGAGAAC

Product: nickel-transporting ATPase

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MFRFFLGRLAVLIPTFIGVSIIAFSFIRLLPGDPVALLSGERVMSPERHAEISRQLGFDRPIVMQYLDYLWGVLQGDFGT
SIVTKRPVMDQFLELFPATVELSLCAIIFAVLVGIPAGVVAAVKRGSIFDQIIMGTALVGFSMPIFWWGLLLIMLVSGTL
QWTPVSGRISLMFYFPSVTGFMLIDSLLSGQEGAFRSALHHLILPTIVLGTIPLAVIARQTRSAMLEVLSEDYVRTARAK
GLSTFRVVGIHALRNAMIPVVTTIGLQIGVMLAGAILTETIFSWPGIGKWLLDSVSRRDYAVIQGGLLIIAAVIMLVNLA
VDLLYGLINPRIRH

Sequences:

>Translated_334_residues
MFRFFLGRLAVLIPTFIGVSIIAFSFIRLLPGDPVALLSGERVMSPERHAEISRQLGFDRPIVMQYLDYLWGVLQGDFGT
SIVTKRPVMDQFLELFPATVELSLCAIIFAVLVGIPAGVVAAVKRGSIFDQIIMGTALVGFSMPIFWWGLLLIMLVSGTL
QWTPVSGRISLMFYFPSVTGFMLIDSLLSGQEGAFRSALHHLILPTIVLGTIPLAVIARQTRSAMLEVLSEDYVRTARAK
GLSTFRVVGIHALRNAMIPVVTTIGLQIGVMLAGAILTETIFSWPGIGKWLLDSVSRRDYAVIQGGLLIIAAVIMLVNLA
VDLLYGLINPRIRH
>Mature_334_residues
MFRFFLGRLAVLIPTFIGVSIIAFSFIRLLPGDPVALLSGERVMSPERHAEISRQLGFDRPIVMQYLDYLWGVLQGDFGT
SIVTKRPVMDQFLELFPATVELSLCAIIFAVLVGIPAGVVAAVKRGSIFDQIIMGTALVGFSMPIFWWGLLLIMLVSGTL
QWTPVSGRISLMFYFPSVTGFMLIDSLLSGQEGAFRSALHHLILPTIVLGTIPLAVIARQTRSAMLEVLSEDYVRTARAK
GLSTFRVVGIHALRNAMIPVVTTIGLQIGVMLAGAILTETIFSWPGIGKWLLDSVSRRDYAVIQGGLLIIAAVIMLVNLA
VDLLYGLINPRIRH

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=337, Percent_Identity=61.4243323442137, Blast_Score=435, Evalue=1e-123,
Organism=Escherichia coli, GI1787053, Length=338, Percent_Identity=42.0118343195266, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI1787761, Length=316, Percent_Identity=46.2025316455696, Blast_Score=238, Evalue=4e-64,
Organism=Escherichia coli, GI1787550, Length=266, Percent_Identity=40.9774436090226, Blast_Score=223, Evalue=1e-59,
Organism=Escherichia coli, GI1789888, Length=335, Percent_Identity=35.5223880597015, Blast_Score=207, Evalue=9e-55,
Organism=Escherichia coli, GI1787497, Length=335, Percent_Identity=34.9253731343284, Blast_Score=191, Evalue=4e-50,
Organism=Escherichia coli, GI1788504, Length=296, Percent_Identity=31.7567567567568, Blast_Score=138, Evalue=6e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 36596; Mature: 36596

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRFFLGRLAVLIPTFIGVSIIAFSFIRLLPGDPVALLSGERVMSPERHAEISRQLGFDR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHCCCHHHHHHHHHCCCCC
PIVMQYLDYLWGVLQGDFGTSIVTKRPVMDQFLELFPATVELSLCAIIFAVLVGIPAGVV
HHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHH
AAVKRGSIFDQIIMGTALVGFSMPIFWWGLLLIMLVSGTLQWTPVSGRISLMFYFPSVTG
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEEEEECHHHH
FMLIDSLLSGQEGAFRSALHHLILPTIVLGTIPLAVIARQTRSAMLEVLSEDYVRTARAK
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLSTFRVVGIHALRNAMIPVVTTIGLQIGVMLAGAILTETIFSWPGIGKWLLDSVSRRDY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCH
AVIQGGLLIIAAVIMLVNLAVDLLYGLINPRIRH
HHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MFRFFLGRLAVLIPTFIGVSIIAFSFIRLLPGDPVALLSGERVMSPERHAEISRQLGFDR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHCCCHHHHHHHHHCCCCC
PIVMQYLDYLWGVLQGDFGTSIVTKRPVMDQFLELFPATVELSLCAIIFAVLVGIPAGVV
HHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHH
AAVKRGSIFDQIIMGTALVGFSMPIFWWGLLLIMLVSGTLQWTPVSGRISLMFYFPSVTG
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEEEEECHHHH
FMLIDSLLSGQEGAFRSALHHLILPTIVLGTIPLAVIARQTRSAMLEVLSEDYVRTARAK
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLSTFRVVGIHALRNAMIPVVTTIGLQIGVMLAGAILTETIFSWPGIGKWLLDSVSRRDY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCH
AVIQGGLLIIAAVIMLVNLAVDLLYGLINPRIRH
HHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]