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The map label for this gene is groES

Identifier: 150010352

GI number: 150010352

Start: 4616251

End: 4616520

Strand: Direct

Name: groES

Synonym: BDI_3786

Alternate gene names: 150010352

Gene position: 4616251-4616520 (Clockwise)

Preceding gene: 150010351

Following gene: 150010353

Centisome position: 95.94

GC content: 42.96

Gene sequence:

>270_bases
ATGAACATTAGACCATTAGCAGACCGCGTGCTGATTAAGCCGGCCGCTGCGGAAGAGAAAACATTAGGTGGAATTATTAT
TCCTGACTCAGCAAAGGAAAAGCCTTTAAAGGGTGAGATTGTAGCCGTAGGTAACGGAACGAAAGACGAGGAGATGGTTG
TAAAGGTTGGTGATAACGTATTGTATGGTAAGTATGCAGGTACGGAAATCGAACTAGATGGTGAGAAATACTTGATCATG
CGCCAAGCAGACGTTTTAGCTATTATCTAA

Upstream 100 bases:

>100_bases
GGGTGAATACGTTTGGCACACTATTCGCATAGACTTAGGCGTGAACACAAAGTTCATAAACTAAAAACGTAATATTATTA
ACATTTAAAATACCAAGAAA

Downstream 100 bases:

>100_bases
TTCATTTTTATAAACAACAATATTAAAAAGAAATACAATCATGGCAAAAGAGATTAAATACGATATGGATGCCCGCGACC
TTTTGAAGAAAGGTGTGGAT

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein; Protein Cpn10

Number of amino acids: Translated: 89; Mature: 89

Protein sequence:

>89_residues
MNIRPLADRVLIKPAAAEEKTLGGIIIPDSAKEKPLKGEIVAVGNGTKDEEMVVKVGDNVLYGKYAGTEIELDGEKYLIM
RQADVLAII

Sequences:

>Translated_89_residues
MNIRPLADRVLIKPAAAEEKTLGGIIIPDSAKEKPLKGEIVAVGNGTKDEEMVVKVGDNVLYGKYAGTEIELDGEKYLIM
RQADVLAII
>Mature_89_residues
MNIRPLADRVLIKPAAAEEKTLGGIIIPDSAKEKPLKGEIVAVGNGTKDEEMVVKVGDNVLYGKYAGTEIELDGEKYLIM
RQADVLAII

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family

Homologues:

Organism=Homo sapiens, GI4504523, Length=87, Percent_Identity=43.6781609195402, Blast_Score=63, Evalue=6e-11,
Organism=Escherichia coli, GI1790585, Length=95, Percent_Identity=45.2631578947368, Blast_Score=74, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17555568, Length=93, Percent_Identity=37.6344086021505, Blast_Score=70, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21356029, Length=93, Percent_Identity=39.7849462365591, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21358317, Length=90, Percent_Identity=36.6666666666667, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): CH10_PARD8 (A6LIF9)

Other databases:

- EMBL:   CP000140
- RefSeq:   YP_001305095.1
- ProteinModelPortal:   A6LIF9
- SMR:   A6LIF9
- STRING:   A6LIF9
- GeneID:   5308935
- GenomeReviews:   CP000140_GR
- KEGG:   pdi:BDI_3786
- eggNOG:   COG0234
- HOGENOM:   HBG703377
- OMA:   QDRIIVK
- ProtClustDB:   PRK00364
- BioCyc:   PDIS435591:BDI_3786-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00580
- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032
- Gene3D:   G3DSA:2.30.33.40
- PANTHER:   PTHR10772
- PRINTS:   PR00297
- SMART:   SM00883

Pfam domain/function: PF00166 Cpn10; SSF50129 GroES_like

EC number: NA

Molecular weight: Translated: 9608; Mature: 9608

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIRPLADRVLIKPAAAEEKTLGGIIIPDSAKEKPLKGEIVAVGNGTKDEEMVVKVGDNV
CCCCCCCCEEEECCCCCCCCCCCCEECCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCE
LYGKYAGTEIELDGEKYLIMRQADVLAII
EEEEECCCEEEECCCEEEEEECCEEEEEC
>Mature Secondary Structure
MNIRPLADRVLIKPAAAEEKTLGGIIIPDSAKEKPLKGEIVAVGNGTKDEEMVVKVGDNV
CCCCCCCCEEEECCCCCCCCCCCCEECCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCE
LYGKYAGTEIELDGEKYLIMRQADVLAII
EEEEECCCEEEECCCEEEEEECCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA