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The map label for this gene is trpS [H]

Identifier: 150010033

GI number: 150010033

Start: 4208179

End: 4209231

Strand: Direct

Name: trpS [H]

Synonym: BDI_3452

Alternate gene names: 150010033

Gene position: 4208179-4209231 (Clockwise)

Preceding gene: 150010032

Following gene: 150010034

Centisome position: 87.46

GC content: 46.06

Gene sequence:

>1053_bases
ATGGAAACAGTAGTAAGTGGAATCAGACCAACAGGTAATCTGCATCTAGGCAATTACTTTGGTGCGGTAAAGAGTTTCTT
GCGGATGCAAGATGAGTATAATTGCTTCTTCTTTATCGCTGATTGGCATTCGTTGACTACTCACCCGCATCCTGACAATA
TACGAAATAGCGTAAAGACGATCCTCTCGGAATATCTGGCTTGTGGTATCGATCCGGAAAAAGCTACCATTTATATTCAG
AGCGATGTGCCGGAGGTGGTAGAGTTGTATCTATATTTGAATATGAACGCCGGTATCGGCGAGTTGATGCGTACGGCTTC
CTTTAAGGATAAGGCCCGTCAGCAGTTGCATATCAGCCGGGAAGGATGTGAAGGCGATGTAGAGAAAGAGATTTTTAATG
AAGGTAATAAACATAGCGTAAGCGCTGGTTTGTTGACTTACCCGACCTTGATGGCCGCCGATATTATTATCCATAAGGCG
TTGAAGGTTCCTGTAGGTAAGGATCAGGAGCAGAATATGGAAATGGCCCGTCGTTTCGCCCGCCGTTTCAATTCTACGTA
TGGCGTGGATTTCTTCCCGGAACCTGCGTCGTTCCATTTGGGCAATAAGTCCGTGAAAGTACCGGGCTTGGATGGCTCCG
GTAAGATGGGCAAGAGTGAGGGTAACGCGATCTATTTGATAGATGATGAGAAAACAATCAAGAAGAAGGTTATGAAAGCG
GTTTCCGATGCGGGACCAACCGAGCCGAATAGCGTGAAGCCCGAGCCGATCGCCAATTTATTCACGATGATGGAAATTGT
CTCCGAGAAAGAGACCTATGATTTCTTTAATGAGAAATACAACAATTGCGAGATCCGTTACGGCGATATGAAAAAGCAGT
TGGCCGAGGATATCAATAAGTTCTGCGCTCCGATCCGTGAGCGTATCTTGGATATGGCCGCCAATACGGAATATCTGGAT
AAGGTAGCCCGTATGGGTGCGGAGAAAGCTCGTGAGAGCGCTTCTAAGACTTTAAATGAGGTACGCCAGATTATCGGTTT
TCGTCCATATTGA

Upstream 100 bases:

>100_bases
GTTATAATAGGTGGTTAGGAGGATCTGCGGCATATAATATATGTATATTGTGAGAATATTACTATCTTTGCCGCCACTTG
AAAACTAAAAATAACAAGAC

Downstream 100 bases:

>100_bases
TGCTTATTAATTAAAAATAAGAAAAAGCGTTTAGGGATAAGTCCTTAAACGCTTTCTTTTTATTAAAACCATTATAAAGA
ACCTGAAAAGCGATTTGTTA

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
METVVSGIRPTGNLHLGNYFGAVKSFLRMQDEYNCFFFIADWHSLTTHPHPDNIRNSVKTILSEYLACGIDPEKATIYIQ
SDVPEVVELYLYLNMNAGIGELMRTASFKDKARQQLHISREGCEGDVEKEIFNEGNKHSVSAGLLTYPTLMAADIIIHKA
LKVPVGKDQEQNMEMARRFARRFNSTYGVDFFPEPASFHLGNKSVKVPGLDGSGKMGKSEGNAIYLIDDEKTIKKKVMKA
VSDAGPTEPNSVKPEPIANLFTMMEIVSEKETYDFFNEKYNNCEIRYGDMKKQLAEDINKFCAPIRERILDMAANTEYLD
KVARMGAEKARESASKTLNEVRQIIGFRPY

Sequences:

>Translated_350_residues
METVVSGIRPTGNLHLGNYFGAVKSFLRMQDEYNCFFFIADWHSLTTHPHPDNIRNSVKTILSEYLACGIDPEKATIYIQ
SDVPEVVELYLYLNMNAGIGELMRTASFKDKARQQLHISREGCEGDVEKEIFNEGNKHSVSAGLLTYPTLMAADIIIHKA
LKVPVGKDQEQNMEMARRFARRFNSTYGVDFFPEPASFHLGNKSVKVPGLDGSGKMGKSEGNAIYLIDDEKTIKKKVMKA
VSDAGPTEPNSVKPEPIANLFTMMEIVSEKETYDFFNEKYNNCEIRYGDMKKQLAEDINKFCAPIRERILDMAANTEYLD
KVARMGAEKARESASKTLNEVRQIIGFRPY
>Mature_350_residues
METVVSGIRPTGNLHLGNYFGAVKSFLRMQDEYNCFFFIADWHSLTTHPHPDNIRNSVKTILSEYLACGIDPEKATIYIQ
SDVPEVVELYLYLNMNAGIGELMRTASFKDKARQQLHISREGCEGDVEKEIFNEGNKHSVSAGLLTYPTLMAADIIIHKA
LKVPVGKDQEQNMEMARRFARRFNSTYGVDFFPEPASFHLGNKSVKVPGLDGSGKMGKSEGNAIYLIDDEKTIKKKVMKA
VSDAGPTEPNSVKPEPIANLFTMMEIVSEKETYDFFNEKYNNCEIRYGDMKKQLAEDINKFCAPIRERILDMAANTEYLD
KVARMGAEKARESASKTLNEVRQIIGFRPY

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=353, Percent_Identity=33.9943342776204, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI41352700, Length=196, Percent_Identity=40.8163265306122, Blast_Score=149, Evalue=3e-36,
Organism=Escherichia coli, GI1789786, Length=353, Percent_Identity=35.4107648725212, Blast_Score=206, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI71982800, Length=355, Percent_Identity=32.3943661971831, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI71982793, Length=355, Percent_Identity=32.3943661971831, Blast_Score=175, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6320474, Length=359, Percent_Identity=33.7047353760446, Blast_Score=174, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24666151, Length=349, Percent_Identity=33.810888252149, Blast_Score=175, Evalue=4e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 39541; Mature: 39541

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METVVSGIRPTGNLHLGNYFGAVKSFLRMQDEYNCFFFIADWHSLTTHPHPDNIRNSVKT
CCCHHCCCCCCCCEECHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHH
ILSEYLACGIDPEKATIYIQSDVPEVVELYLYLNMNAGIGELMRTASFKDKARQQLHISR
HHHHHHHCCCCCCCEEEEEECCCHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHH
EGCEGDVEKEIFNEGNKHSVSAGLLTYPTLMAADIIIHKALKVPVGKDQEQNMEMARRFA
CCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
RRFNSTYGVDFFPEPASFHLGNKSVKVPGLDGSGKMGKSEGNAIYLIDDEKTIKKKVMKA
HHHCCCCCCCCCCCCCCEECCCCEEECCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHH
VSDAGPTEPNSVKPEPIANLFTMMEIVSEKETYDFFNEKYNNCEIRYGDMKKQLAEDINK
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHH
FCAPIRERILDMAANTEYLDKVARMGAEKARESASKTLNEVRQIIGFRPY
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
METVVSGIRPTGNLHLGNYFGAVKSFLRMQDEYNCFFFIADWHSLTTHPHPDNIRNSVKT
CCCHHCCCCCCCCEECHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHH
ILSEYLACGIDPEKATIYIQSDVPEVVELYLYLNMNAGIGELMRTASFKDKARQQLHISR
HHHHHHHCCCCCCCEEEEEECCCHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHH
EGCEGDVEKEIFNEGNKHSVSAGLLTYPTLMAADIIIHKALKVPVGKDQEQNMEMARRFA
CCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
RRFNSTYGVDFFPEPASFHLGNKSVKVPGLDGSGKMGKSEGNAIYLIDDEKTIKKKVMKA
HHHCCCCCCCCCCCCCCEECCCCEEECCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHH
VSDAGPTEPNSVKPEPIANLFTMMEIVSEKETYDFFNEKYNNCEIRYGDMKKQLAEDINK
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHH
FCAPIRERILDMAANTEYLDKVARMGAEKARESASKTLNEVRQIIGFRPY
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12949112 [H]