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The map label for this gene is fabF [H]

Identifier: 150009419

GI number: 150009419

Start: 3370701

End: 3371966

Strand: Direct

Name: fabF [H]

Synonym: BDI_2827

Alternate gene names: 150009419

Gene position: 3370701-3371966 (Clockwise)

Preceding gene: 150009417

Following gene: 150009420

Centisome position: 70.06

GC content: 46.68

Gene sequence:

>1266_bases
ATGGAATTAAAAAGAGTTGTAGTAACAGGTCTTGGAGCTATTACTCCTCTTGGTAATACCCTCCCCGAAACATGGGAAGG
TATTATCAACGGAAAAAGTGGCGCTGGACCTATTACTCAGTTTGATGCATCCAAATTCAAGACACAATTTGCATGCGAAG
TTAAAGGCTTCGATCCGTTGAAAGTTATGGATCGTAAGGAAGCCCGCAAGTGTGATCGTTATAGCTTATTCGCGATCGAT
GCGGCGAAACAAGCGATCGAGGACGCGGCAATGGACTTGGATAAAGAAGATAAGAACCGTATCGGCGTTATTTTCGCTTC
AGGTATCGGTGGTATCAAGACATTTGACGAGGAAGTATTGAGTTATGCGAAGATCAAGGATACGATCGGTCCGAAGTTTA
ACCCGTTCTTCATCCCGAAAATGATCTCGGATATCGCGGCTGGACATATTTCCATGCTTTATGGATTCCACGGCCCGAAC
TTTGCGACCGTCTCAGCTTGTGCATCTTCTACAAACGCTATCAGCGACGCATTCAATTATATCCGTTTAGGCAAGGCTAA
CGTCATCATCACCGGTGGAGCGGAAGCTGCTGTTTCTGAATCGGGTGTAGGTGGATTCAACTCCATGAACGCGTTATCGA
CACGTAACGATTCTCCCGAGACCGCATCTCGCCCGTTCAGCGCTAGCCGTGACGGATTCGTGATGGGTGAAGGTGGAGCT
TGCTTGGTATTGGAAGAAATGGAGCACGCATTGGCTCGTGGCGCTAAAATATATTGCGAGATCGCAGGAACCGGAATGTC
TGCCGATGCCTATCACTTGACCGCTTCTCATCCGGATGGTTTAGGAGCGAAGCTGGTTATGCGCAACGCATTGGAAGACG
CTGGAATGGCTCCGGAAGATATTGATTACATCAATGTTCATGGAACATCGACTCCCGTAGGCGATATCTCAGAGGTTAAG
GCGATCAAAGATGTGTTCGGAGAACATGCTTATCAACTGAATATCAGTTCCACAAAGTCAATGACCGGTCACTTGCTTGG
TGCTGCCGGAGCGGTAGAGGCGATCCTGTGTATTATGGCTATAAACGATGGTATTATCCCGCCGACCATTAACCATGCGG
AAGGCGACGATGATCCTGAAATAGATTATAAACTGAATTTCACATTCAATAAGGCTCAAAAGAGAGAAGTGAAAGCCGCT
TTATCGAATACGTTTGGTTTCGGTGGACACAACGCTTGCGCCATTGTTAAAAAATTCGTGAAATAA

Upstream 100 bases:

>100_bases
CTCAATTCCTGACGATCAAGCAGAAAAGATTACAACTGTAGGTGACGCTATCGCTTACATCGAGGCTAATGCGAAGTAAT
CAATCCTTTTAACTAAAGGT

Downstream 100 bases:

>100_bases
CGTGTTTAGAAAGCTATACAAACAGCTACATAAAAGAATAAGGCTCCTGCATAATAAAGGTAGGGAGCCTTATTTGTCTT
TATCAAAGATTCTAGGTTTT

Product: putative 3-oxoacyl-[acyl-carrier-protein] synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MELKRVVVTGLGAITPLGNTLPETWEGIINGKSGAGPITQFDASKFKTQFACEVKGFDPLKVMDRKEARKCDRYSLFAID
AAKQAIEDAAMDLDKEDKNRIGVIFASGIGGIKTFDEEVLSYAKIKDTIGPKFNPFFIPKMISDIAAGHISMLYGFHGPN
FATVSACASSTNAISDAFNYIRLGKANVIITGGAEAAVSESGVGGFNSMNALSTRNDSPETASRPFSASRDGFVMGEGGA
CLVLEEMEHALARGAKIYCEIAGTGMSADAYHLTASHPDGLGAKLVMRNALEDAGMAPEDIDYINVHGTSTPVGDISEVK
AIKDVFGEHAYQLNISSTKSMTGHLLGAAGAVEAILCIMAINDGIIPPTINHAEGDDDPEIDYKLNFTFNKAQKREVKAA
LSNTFGFGGHNACAIVKKFVK

Sequences:

>Translated_421_residues
MELKRVVVTGLGAITPLGNTLPETWEGIINGKSGAGPITQFDASKFKTQFACEVKGFDPLKVMDRKEARKCDRYSLFAID
AAKQAIEDAAMDLDKEDKNRIGVIFASGIGGIKTFDEEVLSYAKIKDTIGPKFNPFFIPKMISDIAAGHISMLYGFHGPN
FATVSACASSTNAISDAFNYIRLGKANVIITGGAEAAVSESGVGGFNSMNALSTRNDSPETASRPFSASRDGFVMGEGGA
CLVLEEMEHALARGAKIYCEIAGTGMSADAYHLTASHPDGLGAKLVMRNALEDAGMAPEDIDYINVHGTSTPVGDISEVK
AIKDVFGEHAYQLNISSTKSMTGHLLGAAGAVEAILCIMAINDGIIPPTINHAEGDDDPEIDYKLNFTFNKAQKREVKAA
LSNTFGFGGHNACAIVKKFVK
>Mature_421_residues
MELKRVVVTGLGAITPLGNTLPETWEGIINGKSGAGPITQFDASKFKTQFACEVKGFDPLKVMDRKEARKCDRYSLFAID
AAKQAIEDAAMDLDKEDKNRIGVIFASGIGGIKTFDEEVLSYAKIKDTIGPKFNPFFIPKMISDIAAGHISMLYGFHGPN
FATVSACASSTNAISDAFNYIRLGKANVIITGGAEAAVSESGVGGFNSMNALSTRNDSPETASRPFSASRDGFVMGEGGA
CLVLEEMEHALARGAKIYCEIAGTGMSADAYHLTASHPDGLGAKLVMRNALEDAGMAPEDIDYINVHGTSTPVGDISEVK
AIKDVFGEHAYQLNISSTKSMTGHLLGAAGAVEAILCIMAINDGIIPPTINHAEGDDDPEIDYKLNFTFNKAQKREVKAA
LSNTFGFGGHNACAIVKKFVK

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=424, Percent_Identity=41.5094339622642, Blast_Score=305, Evalue=4e-83,
Organism=Homo sapiens, GI223972627, Length=147, Percent_Identity=51.7006802721088, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI41872631, Length=440, Percent_Identity=25.4545454545455, Blast_Score=110, Evalue=2e-24,
Organism=Escherichia coli, GI1787337, Length=421, Percent_Identity=47.2684085510689, Blast_Score=347, Evalue=6e-97,
Organism=Escherichia coli, GI1788663, Length=420, Percent_Identity=38.5714285714286, Blast_Score=256, Evalue=2e-69,
Organism=Caenorhabditis elegans, GI71983541, Length=422, Percent_Identity=34.3601895734597, Blast_Score=243, Evalue=2e-64,
Organism=Caenorhabditis elegans, GI71983535, Length=259, Percent_Identity=40.1544401544402, Blast_Score=191, Evalue=7e-49,
Organism=Caenorhabditis elegans, GI212642053, Length=363, Percent_Identity=24.5179063360882, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17550940, Length=274, Percent_Identity=27.3722627737226, Blast_Score=91, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6320904, Length=449, Percent_Identity=34.075723830735, Blast_Score=246, Evalue=7e-66,
Organism=Drosophila melanogaster, GI24644341, Length=429, Percent_Identity=41.2587412587413, Blast_Score=315, Evalue=5e-86,
Organism=Drosophila melanogaster, GI19920632, Length=401, Percent_Identity=26.6832917705736, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI221330659, Length=404, Percent_Identity=26.7326732673267, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24581345, Length=406, Percent_Identity=23.3990147783251, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 44695; Mature: 44695

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELKRVVVTGLGAITPLGNTLPETWEGIINGKSGAGPITQFDASKFKTQFACEVKGFDPL
CCCHHEEHHCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHCEEEEEEECCCCCH
KVMDRKEARKCDRYSLFAIDAAKQAIEDAAMDLDKEDKNRIGVIFASGIGGIKTFDEEVL
HHHCCHHHHCCCCEEEEEEHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHHHH
SYAKIKDTIGPKFNPFFIPKMISDIAAGHISMLYGFHGPNFATVSACASSTNAISDAFNY
HHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHCCCHHHHHHHHH
IRLGKANVIITGGAEAAVSESGVGGFNSMNALSTRNDSPETASRPFSASRDGFVMGEGGA
HEECCCCEEEECCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCC
CLVLEEMEHALARGAKIYCEIAGTGMSADAYHLTASHPDGLGAKLVMRNALEDAGMAPED
EEEHHHHHHHHHCCCEEEEEEECCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCC
IDYINVHGTSTPVGDISEVKAIKDVFGEHAYQLNISSTKSMTGHLLGAAGAVEAILCIMA
CCEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
INDGIIPPTINHAEGDDDPEIDYKLNFTFNKAQKREVKAALSNTFGFGGHNACAIVKKFV
HCCCCCCCCCCCCCCCCCCCEEEEEEEEECHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
K
C
>Mature Secondary Structure
MELKRVVVTGLGAITPLGNTLPETWEGIINGKSGAGPITQFDASKFKTQFACEVKGFDPL
CCCHHEEHHCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHCEEEEEEECCCCCH
KVMDRKEARKCDRYSLFAIDAAKQAIEDAAMDLDKEDKNRIGVIFASGIGGIKTFDEEVL
HHHCCHHHHCCCCEEEEEEHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHHHH
SYAKIKDTIGPKFNPFFIPKMISDIAAGHISMLYGFHGPNFATVSACASSTNAISDAFNY
HHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHCCCHHHHHHHHH
IRLGKANVIITGGAEAAVSESGVGGFNSMNALSTRNDSPETASRPFSASRDGFVMGEGGA
HEECCCCEEEECCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCC
CLVLEEMEHALARGAKIYCEIAGTGMSADAYHLTASHPDGLGAKLVMRNALEDAGMAPED
EEEHHHHHHHHHCCCEEEEEEECCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCC
IDYINVHGTSTPVGDISEVKAIKDVFGEHAYQLNISSTKSMTGHLLGAAGAVEAILCIMA
CCEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
INDGIIPPTINHAEGDDDPEIDYKLNFTFNKAQKREVKAALSNTFGFGGHNACAIVKKFV
HCCCCCCCCCCCCCCCCCCCEEEEEEEEECHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]